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endoscopic treatment of reflux 2017

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https://www.readbyqxmd.com/read/30171395/persistent-dysphagia-is-a-rare-problem-after-laparoscopic-nissen-fundoplication
#1
Milena Nikolic, Katrin Schwameis, Georg Semmler, Reza Asari, Lorenz Semmler, Ariane Steindl, Berta O Mosleh, Sebastian F Schoppmann
BACKGROUND: Although around 30% of patients with gastroesophageal reflux disease (GERD) are insufficiently treated with medical therapy, only 1% opt for surgical therapy. One of the reasons behind this multifactorial phenomenon is the described adverse effect of long-term dysphagia or gastric bloating syndrome after surgical treatment. Aim of this study was to evaluate the most common side effects associated with anti-reflux surgery, as well as long-term outcomes in a large cohort of highly surgically standardized patients after laparoscopic Nissen fundoplication (LNF)...
August 31, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30146426/comparing-treatment-modalities-for-transplant-kidney-vesicoureteral-reflux-in-the-pediatric-population
#2
K R Sheth, J T White, I Stanasel, N Janzen, A Mittal, C J Koh, P F Austin, D R Roth, D D Tu, E T Gonzales, S Ryan, C Jorgez, A Seth
INTRODUCTION: Non-refluxing ureteral reimplantation is favored in pediatric renal transplantation to prevent complications, such as vesicoureteral reflux (VUR) in the transplant ureter. VUR resulting in febrile urinary tract infections remains a problem in this population, leading to repeated hospitalizations and increased morbidity. Revision of the vesicoureteral anastomosis can be a surgical challenge due to scar tissue and tenuous vascularity of the transplant ureter. Therefore, alternative options such as endoscopic injection of Deflux at the neo-orifice and surveillance with prophylactic antibiotics have emerged as potential treatment modalities for transplant ureter VUR...
July 24, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/30106416/efficacy-and-safety-of-endoscopic-dilatation-in-the-management-of-esophageal-strictures-in-children
#3
Ahmed A Al Sarkhy, Anjum Saeed, Yassin H Hamid, Mona M Al Asmi, Tariq I Altokhais, Anhar A Ullah, Asaad M Assiri
OBJECTIVES: To determine the outcomes  of endoscopic dilatation of esophageal strictures in children. METHODS: Children younger than 18 years of age diagnosed with esophageal strictures over a period of 7 years (June 2010 to June 2017) were reviewed and analyzed retrospectively. The study took place at King Khalid University Hospital, Riyadh, Saudi Arabia. The patients' clinical characteristics, endoscopic findings, and details of the strictures, treatment, and outcomes were documented...
August 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29915629/possible-risk-factors-for-candida-esophagitis-in-immunocompetent-individuals
#4
Yousef Nassar, Tony Eljabbour, Hwajeong Lee, Asra Batool
Background: Candida esophagitis (CE) is a condition typically diagnosed in patients who are immunocompromised. Risk factors leading to the development of CE in immunocompetent patients have not been entirely elucidated. This study set out to identify risk factors associated with the development of CE in immunocompetent patients. Methods: This study was a single-center retrospective chart review. Patients diagnosed with CE confirmed by endoscopic biopsy or brushings at our hospital between 2007 and 2017 were reviewed...
June 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29743599/crural-closure-improves-outcomes-of-magnetic-sphincter-augmentation-in-gerd-patients-with-hiatal-hernia
#5
Katrin Schwameis, Milena Nikolic, Deivis G Morales Castellano, Ariane Steindl, Sarah Macheck, M Riegler, Ivan Kristo, Barbara Zörner, Sebastian F Schoppmann
Magnetic sphincter-augmentation (MSA) has been proven effective in the treatment of GERD. No consensus exists on whether crural closure should be performed. Our aim was to assess the impact of cruroplasty on reflux-control and quality of life. MSA-Patients treated between 03/2012-03/2017 were classified into those without hiatal hernia ("NHH"), those post-MSA (NHR) and those post-MSA/hiatal repair (HR). GERD-symptoms, PPI-intake, GERD-Health-related-Quality-of-Life (GERD-HRQL) and Alimentary Satisfaction were assessed...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29725806/randomized-clinical-trial-between-polyacrylate-polyalcohol-copolymer-ppc-and-dextranomer-hyaluronic-acid-copolymer-dx-ha-as-bulking-agents-for-endoscopic-treatment-of-primary-vesicoureteral-reflux-vur
#6
L García-Aparicio, E Blázquez-Gómez, O Martin, S Pérez-Bertólez, J Arboleda, A Soria, X Tarrado
OBJECTIVE: To compare the radiological and clinical outcomes of endoscopic treatment of primary VUR using polyacrylate-polyalcohol copolymer (PPC-Vantris® ) or dextranomer-hyaluronic acid copolymer (Dx/HA-Deflux® ). MATERIALS AND METHODS: From October 2014 to April 2017, patients with primary VUR grade III to V that needed endoscopic treatment (ET) were eligible for this randomized clinical trial. We excluded toilet-trained patients with lower urinary tract symptoms...
October 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29674757/ten-initial-cases-of-peroral-endoscopic-myotomy-for-treatment-of-esophageal-motility-disorders-at-okayama-university-hospital
#7
Yuusaku Sugihara, Keita Harada, Ryo Kato, Kenji Yamauchi, Shiho Takashima, Daisuke Takei, Yasushi Yamasaki, Toshihiro Inokuchi, Masahiro Takahara, Sakiko Hiraoka, Hiroyuki Okada
Peroral endoscopic myotomy (POEM) for treatment of esophageal motility disorders has recently been reported to be highly effective and less invasive than other treatment. POEM was recently introduced in Okayama University Hospital under the supervision of a physician from a high-volume center. To verify the safety and efficacy of POEM during its introduction in our institution. We examined 10 cases in whom POEM was performed between January 2016 and April 2017. The patients included 7 men and 3 women, with a median age (range) of 49 years (17-74) and median symptom duration of 6 years (1-21)...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29625507/efficacy-of-transoral-incisionless-fundoplication-for-refractory-gastroesophageal-reflux-disease-a-systematic-review-and-meta-analysis
#8
Thomas R McCarty, Michael Itidiare, Basile Njei, Tarun Rustagi
BACKGROUND:  Given poor symptomatic response rates and rising awareness of the adverse events associated with the long-term use of proton pump inhibitors (PPIs), endoscopic modalities for treatment of refractory gastroesophageal reflux disease (GERD) have become more prominent. The aim of this study was to perform a systematic review and meta-analysis to evaluate feasibility, efficacy, and tolerability of transoral incisionless fundoplication (TIF) for the treatment of refractory GERD...
July 2018: Endoscopy
https://www.readbyqxmd.com/read/29619511/results-of-magnetic-sphincter-augmentation-for-gastroesophageal-reflux-disease
#9
Katrin Schwameis, Milena Nikolic, Deivis G Morales Castellano, Ariane Steindl, Sarah Macheck, Ivan Kristo, Barbara Zörner, Sebastian F Schoppmann
BACKGROUND: Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center. METHODS: A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up >3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed...
October 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29496268/peroral-endoscopic-myotomy-for-the-treatment-of-achalasia-and-other-esophageal-motor-disorders-short-term-and-medium-term-results-at-a-mexican-tertiary-care-center
#10
O V Hernández-Mondragón, O M Solórzano-Pineda, M A González-Martínez, J M Blancas-Valencia, C Caballero-Luengas
INTRODUCTION AND AIMS: Achalasia is characterized by the absence of lower esophageal sphincter relaxation and esophageal aperistalsis. Diagnosis is confirmed through high-resolution esophageal manometry. Laparoscopic myotomy is the standard treatment, but peroral endoscopic myotomy (POEM) is a safe and effective alternative, with good short-term and medium-term results. Our aim was to describe the short-term and medium-term experience with POEM at a tertiary care center. MATERIALS AND METHODS: The study was conducted within the time frame of November 2014 and February 2017...
February 26, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29492922/-safety-evaluation-on-initial-100-consecutive-procedures-of-self-pulling-and-latter-transected-esophagojejunostomy
#11
Hankun Hao, Jun Hong, Yaping Wang, Jian Wang, Yibing Bei, Luchun Hua
OBJECTIVE: To evaluate the feasibility and the short-term safety of self-pulling and latter transected esophagojejunostomy(SPLT) in totally laparoscopic total gastrectomy (TLTG). METHODS: One hundred patients with gastric cancer received TLTG-SPLT at General Surgery Department of Huashan Hospital (Fudan University) from June 2014 to January 2017(SPLT group). The clinicopathologic characteristics, surgical and postoperative outcomes were collected retrospectively and compared with the conventional group undergoing TLTG plus overlap or functional end-to-end anastomosis from October 2013 to December 2015...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29471155/early-results-of-magnetic-sphincter-augmentation-versus-fundoplication-for-gastroesophageal-reflux-disease-systematic-review-and-meta-analysis
#12
REVIEW
Alberto Aiolfi, Emanuele Asti, Daniele Bernardi, Gianluca Bonitta, Emanuele Rausa, Stefano Siboni, Luigi Bonavina
BACKGROUND: Laparoscopic Nissen and Toupet fundoplication (LF) are currently considered gold-standard surgical treatment for Gastroesophageal Reflux Disease (GERD). Magnetic Sphincter Augmentation (MSA) is an innovative surgical procedure that has been showed to be effective to control GERD symptoms and to reduce esophageal acid exposure. The aim of this systematic review and meta-analysis was to compare early outcomes of LF and MSA. MATERIALS AND METHODS: PubMed, MEDLINE, Embase, and Cochrane databases were consulted matching the terms "Gastroesophageal reflux or heartburn", "LINX or magnetic sphincter augmentation" and "fundoplication"...
April 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29367036/outcomes-after-laparoscopic-anti-reflux-surgery-related-to-obesity-a-systematic-review-and-meta-analysis
#13
REVIEW
T Abdelrahman, A Latif, D S Chan, H Jones, M Farag, W G Lewis, T Havard, X Escofet
BACKGROUND: Laparoscopic Anti-Reflux Surgery (LARS) is an established alternative treatment to pharmacological therapy for patients with Gastro Osophageal Reflux Disease (GORD), yet its safety and efficacy in obese patients is controversial. A systematic review and meta-analysis was performed to compare LARS related to obesity. METHODS: Embase, MEDLINE and the Cochrane Library (January 1970 to July 2017) were searched for studies reporting clinical outcomes of LARS in patient cohorts stratified by Body Mass Index (BMI)...
March 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29365373/-evaluation-and-treatment-of-children-s-laryngeal-clefts
#14
C Chen, L T Tan, Z M Xu
Objectives: To provide the experience about the diagnostic process and following management, and to discuss the outcome and predictors in children with laryngeal cleft (LC). Methods: A retrospective case study was conducted at an academic children's hospital. Thirty children were diagnosed as laryngeal cleft between January 2016 and April 2017.Airway evaluations were performed using both flexible and rigid endoscopy, and swallowing evaluations were performed using fiberoptic endoscopic examination of swallowing or modified barium swallow...
January 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29305934/efficacy-of-laparoscopic-nissen-fundoplication-vs-transoral-incisionless-fundoplication-or-proton-pump-inhibitors-in-patients-with-gastroesophageal-reflux-disease-a-systematic-review-and-network-meta-analysis
#15
REVIEW
Joel E Richter, Ambuj Kumar, Seth Lipka, Branko Miladinovic, Vic Velanovich
BACKGROUND & AIMS: The effects of transoral incisionless fundoplication (TIF) and laparoscopic Nissen fundoplication (LNF) have been compared with those of proton pump inhibitors (PPIs) or a sham procedure in patients with gastroesophageal reflux disease (GERD), but there has been no direct comparison of TIF vs LNF. We performed a systematic review and network meta-analysis of randomized controlled trials to compare the relative efficacies of TIF vs LNF in patients with GERD. METHODS: We searched publication databases and conference abstracts through May 10, 2017 for randomized controlled trials that compared the efficacy of TIF or LNF with that of a sham procedure or PPIs in patients with GERD...
April 2018: Gastroenterology
https://www.readbyqxmd.com/read/29250106/update-on-the-management-of-barrett-s-esophagus-in-austria
#16
M Riegler, I Kristo, M Nikolic, E Rieder, S F Schoppmann
Background: Barrett's esophagus (BE) is the premalignant manifestation of gastroesophageal reflux disease (GERD). Radiofrequency ablation (RFA) with and without endoscopic resection (ER) is a novel treatment for BE. Methods: Here we present a single-center update of the recommendations of a recent (June 2015) interdisciplinary expert panel meeting on the management of BE with dysplasia as well as cancer-positive and cancer-negative BE. We conducted a PubMed search of studies published in 2016 and 2017 on the topic of BE and RFA...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29102729/gerd-after-per-oral-endoscopic-myotomy-as-compared-with-heller-s-myotomy-with-fundoplication-a-systematic-review-with-meta-analysis
#17
REVIEW
Alessandro Repici, Lorenzo Fuccio, Roberta Maselli, Fabrizio Mazza, Loredana Correale, Daniele Mandolesi, Cristina Bellisario, Amrita Sethi, Mouen A Khashab, Thomas Rösch, Cesare Hassan
BACKGROUND AND AIMS: Per-oral endoscopic myotomy (POEM) represents a less invasive alternative to conventional laparoscopic Heller's myotomy (LHM) for patients with achalasia. It cannot be excluded, however, that the lack of fundoplication after POEM may result in a higher incidence of reflux disease, as compared with LHM. The aim of our study was to conduct a systematic review of prospective studies reporting the incidence of reflux disease developed after POEM and LHM. METHODS: A literature search with electronic databases was performed (up to February 2017) to identify full articles on the incidence of gastroesophageal reflux symptoms and endoscopic monitoring and pH monitoring findings after POEM and LHM (with fundoplication)...
April 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27618753/esophageal-adenocarcinoma-screening-surveillance-and-management
#18
REVIEW
Nabil M Mansour, Shawn S Groth, Sharmila Anandasabapathy
Esophageal adenocarcinoma (EAC) is a growing problem with a rapidly rising incidence. Risk factors include gastroesophageal reflux disease, central obesity, and smoking. The prognosis of EAC remains poor because it is usually diagnosed late, and many efforts have been made to improve prevention, early detection, and treatment. Acid suppression, nonsteroidal antiinflammatory drugs (NSAIDs), and statins may play a role in chemoprevention. Screening for Barrett's esophagus (BE), the only known precursor lesion of EAC, is indicated for individuals with increased risk...
January 14, 2017: Annual Review of Medicine
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