keyword
MENU ▼
Read by QxMD icon Read
search

carotid body

keyword
https://www.readbyqxmd.com/read/30102783/fitting-ntcp-models-to-sbrt-dose-and-carotid-blowout-syndrome-data
#1
Panayiotis Mavroidis, Jimm Grimm, Mustafa Cengiz, Shiva Das, Xianming Tan, Gozde Yazici, Gokhan Ozyigit
PURPOSE: To estimate the radiobiological parameters of three popular NTCP models, which describe the dose-response relations of carotid blowout syndrome (CBOS) after stereotactic body radiotherapy (SBRT). To evaluate the goodness-of-fit and the correlation of those models with CBOS. METHODS: The study included 61 patients with inoperable locally recurrent head and neck cancer treated with SBRT using CyberKnife (Accuray, Sunnyvale, CA) at the Department of Radiation Oncology, Hacettepe University, Ankara, Turkey between June 2007 and March 2011...
August 13, 2018: Medical Physics
https://www.readbyqxmd.com/read/30101218/immunohistochemistry-of-the-circadian-clock-in-mouse-and-human-vascular-tissues
#2
Ciprian B Anea, Ana M Merloiu, David J R Fulton, Vijay Patel, R Dan Rudic
Aim: The circadian clock is a molecular network that controls the body physiological rhythms. In blood vessels, the circadian clock components modulate vascular remodeling, blood pressure, and signaling. The goal in this study was to determine the pattern of expression of circadian clock proteins in the endothelium, smooth muscle, and adventitia of the vasculature of human and mouse tissues. Methods: Immunohistochemistry was performed in frozen sections of mouse aorta, common carotid artery, femoral artery, lung, and heart at 12 AM and 12 PM for Bmal1, Clock, Npas2, Per and other clock components...
2018: Vessel plus
https://www.readbyqxmd.com/read/30099048/association-of-serum-sestrin2-level-with-metabolic-risk-factors-in-newly-diagnosed-drug-na%C3%A3-ve-type-2-diabetes
#3
Hye Soo Chung, Hwan-Jin Hwang, Soon Young Hwang, Nam Hoon Kim, Ji-A Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi, Hye Jin Yoo
AIMS: Previous in-vitro and in-vivo experimental studies have shown that Sestrin2 attenuates oxidative stress and the pro-inflammatory pathway, resulting in improving metabolic homeostasis. However, the relationship between circulating Sestrin2 concentration and cardiometabolic risks in humans has not been explored. METHODS: Sestrin2 concentration was measured in 240 subjects (46 without diabetes and 194 with diabetes), and the associations between Sestrin2 level and various cardiometabolic risk factors including body composition, insulin resistance, and atherosclerosis was assessed...
August 9, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/30091539/-effect-of-catgut-implantation-on-spatial-learning-memory-ability-expression-of-hippocampal-protein-kinase-c-interacting-protein-1-and-glur-2-and-ca-2-content-in-rats-with-chronic-ischemic-cognitive-impairment
#4
Shuai Li, Jie Tan, Hong Zhang, Gui-Lan Huang, Duo-Xi Deng, Kui-Kui Guo, Jia-Qing Liu, Tong-Yan Liu, Yun-Yun Wu
OBJECTIVE: To observe the effect of catgut embedment at "Baihui" (GV 20), "Dazhui" (GV 14), etc. on learning-memory ability, expression of hippocampal protein kinase C interacting protein 1 (PICK 1) and glutamate receptor 2 (GluR 2) proteins and level of calcium ions, so as to explore its mechanism underlying improvement of vascular cognitive impairment. METHODS: A total of 56 male SD rats were randomly divided into sham operation, model, catgut embedment and medication groups ( n =14 in each)...
June 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/30091538/-electroacupuncture-combined-with-intracerebral-injection-of-vegf-improves-neurological-dysfunction-possibly-by-down-regulating-expression-of-endoplasmic-reticulum-stress-related-proteins-atf-6-etc-in-cerebral-ischemia-reperfusion-injury-rats
#5
Jia-Peng Wu, Xue-Zhi Li, Ying Wang, Lin Ma, Tai-Wan Yao, Yong-Yue Zhang, Fei Long
OBJECTIVE: To observe the effect of electroacupuncture (EA) and EA combined with intracerebral injection of vascular endothelial growth factor (VEGF) on endoplasmic reticulum stress (ERS) related proteins and genes as activating transcription factor (ATF 6), inositol requiring enzyme-1 (IRE 1), CCAAT/enhancer binding protein homologous protein (CHOP), X box-binding protein-1 (XBP 1) of cerebral ischemia reperfusion injury (CIRI) rats, so as to study its repair effect for CIRI. METHODS: Forty male SD rats were equally and randomly divided into 5 groups: sham operation, model, EA, VEGF and EA+VEGF groups ( n =8)...
June 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/30091061/effect-of-atorvastatin-on-dyslipidemia-and-carotid-intima-media-thickness-in-children-with-refractory-nephrotic-syndrome-a-randomized-controlled-trial
#6
Pankaj Hari, Priyanka Khandelwal, Amit Satpathy, Smriti Hari, Ranjeet Thergaonkar, R Lakshmy, Aditi Sinha, Arvind Bagga
BACKGROUND: Dyslipidemia is an important cardiovascular risk factor in steroid-resistant nephrotic syndrome (SRNS). Efficacy of statins for treatment of hyperlipidemia in children with SRNS is unclear. METHODS: This prospective, randomized, double-blind, placebo-controlled, parallel-group clinical trial enrolled 30 patients with SRNS, aged 5-18 years, with serum low-density lipoprotein cholesterol (LDL-C) levels between 130 and 300 mg/dl, to receive a fixed dose of atorvastatin (n = 15, 10 mg/d) or placebo (n = 15) by block randomization in a 1:1 ratio...
August 8, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/30087079/inflammation-coupling-between-unstable-carotid-plaque-and-spleen-a-18-f-fluorodeoxyglucos-positron-emission-tomography-study
#7
Daina Kashiwazaki, Shusuke Yamamoto, Naoki Akioka, Naoya Kuwayama, Kyo Noguchi, Satoshi Kuroda
BACKGROUND AND PURPOSE: This study was aimed to assess the hypothesis that unstable plaque formation in the carotid artery is one of phenotypes of chronic and systemic inflammation. METHODS: This study included 8 symptomatic patients with internal carotid stenosis (ICS) and 7 healthy controls. All subjects underwent 18 F-fluorodeoxyglucos positron emission tomography (18 F-FDG PET) of whole body. Plaque vulnerability was evaluated on magnetic resonance imaging (MRI)...
August 4, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30086385/h-2-s-mediates-carotid-body-response-to-hypoxia-but-not-anoxia
#8
Ying-Jie Peng, Vladislav V Makarenko, Anna Gridina, Irina Chupikova, Xiuli Zhang, Ganesh K Kumar, Aaron P Fox, Nanduri R Prabhakar
The role of cystathionine-γ-lyase (CSE) derived H2 S in the hypoxic and anoxic responses of the carotid body (CB) were examined. Experiments were performed on Sprague-Dawley rats, wild type and CSE knockout mice on C57BL/6 J background. Hypoxia (pO2  = 37 ± 3 mmHg) increased the CB sensory nerve activity and elevated H2 S levels in rats. In contrast, anoxia (pO2  = 5 ± 4 mmHg) produced only a modest CB sensory excitation with no change in H2 S levels. DL-propargylglycine (DL-PAG), a blocker of CSE, inhibited hypoxia but not anoxia-evoked CB sensory excitation and [Ca2+ ]i elevation of glomus cells...
August 4, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/30076407/impaired-hdl-cholesterol-efflux-capacity-in-patients-with-non-alcoholic-fatty-liver-disease-is-associated-with-subclinical-atherosclerosis
#9
Reza Fadaei, Hossein Poustchi, Reza Meshkani, Nariman Moradi, Taghi Golmohammadi, Shahin Merat
Non-alcoholic fatty liver disease (NAFLD) is associated with a substantial increased risk of atherosclerotic cardiovascular disease (ASCVD), which is partly related to dyslipidemia and low HDL-C level. The cardioprotective activity of HDL in the body is closely connected to its role in promoting cholesterol efflux, which is determined by cholesterol efflux capacity (CEC). Hitherto, the role of HDL, as defined by CEC has not been assessed in NAFLD patients. In this research study, we present the results of a study of cAMP-treated J774 CEC and THP-1 macrophage CEC in ApoB-depleted plasma of 55 newly diagnosed NAFLD patients and 30 controls...
August 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30075120/evaluation-of-carotid-intima-media-thickness-and-factors-associated-with-cardiovascular-disease-in-children-and-adolescents-with-chronic-kidney-disease
#10
Renata Lopes, Mauro Batista de Morais, Fernanda Luisa Ceragioli Oliveira, Ana Paula Brecheret, Ana Lucia Cardoso Santos Abreu, Maria Cristina de Andrade
OBJECTIVE: To assess the carotid intima-media thickness and factors associated with cardiovascular disease in children and adolescents with chronic kidney disease. MATERIAL AND METHODS: Observational, cross-sectional study carried out at the Universidade Federal de São Paulo (chronic kidney disease outpatient clinics) with 55 patients (60% males) with a median age of 11.9 years (I25-I75: 9.2-14.8 years). Of the 55 patients, 43 were on conservative treatment and 12 were on dialysis...
July 31, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/30074003/subclinical-atherosclerosis-and-impaired-cardiac-autonomic-control-in-pediatric-patients-with-vitamin-b12-deficiency
#11
S F Celik, E Celik
Objective: Homocysteine (Hcy) is an independent risk factor for predisposing to atherosclerosis and endothelial dysfunction. Hcy levels increase with Vitamin B12 deficiency. The aim of this study was to investigate the association between carotid intima-media thickness (CIMT) and the autonomic modulation of heart rate variability (HRV) in early detection of atherosclerosis and impaired cardiac autonomic control in pediatric patients with Vitamin B12 deficiency. Materials and Methods: Sixty patients with Vitamin B12 deficiency (14...
August 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/30073874/carotid-intima-media-thickness-and-ankle-brachial-index-are-inversely-associated-in-subjects-with-and-without-diabetes
#12
Karoline Winckler, Niels Wiinberg, Andreas Kryger Jensen, Birger Thorsteinsson, Louise Lundby-Christensen, Berit Lilienthal Heitmann, Gorm Boje Jensen, Lise Tarnow
Carotid intima-media thickness (IMT) and ankle brachial index (ABI) are non-invasive indicators of generalised atherosclerosis. The aim was to determine the association between carotid IMT and ABI in subjects with and without diabetes mellitus (DM), and to analyse specific age change-points. We included 2744 subjects from the Copenhagen City Heart Study (mean age (SD) 56.6 (17.2) years, 56.8% women and body mass index (BMI) 25.4 (4.1) kg/m2 ). Carotid IMT and ABI measurements were performed during the fifth examination...
August 3, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/30065507/a-review-of-medical-doppler-ultrasonography-of-blood-flow-in-general-and-especially-in-common-carotid-artery
#13
REVIEW
Ammar A Oglat, M Z Matjafri, Nursakinah Suardi, Mohammad A Oqlat, Mostafa A Abdelrahman, Ahmad A Oqlat
Medical Doppler ultrasound is usually utilized in the clinical adjusting to evaluate and estimate blood flow in both the major (large) and the minor (tiny) vessels of the body. The normal and abnormal sign waveforms can be shown by spectral Doppler technique. The sign waveform is individual to each vessel. Thus, it is significant for the operator and the clinicians to understand the normal and abnormal diagnostic in a spectral Doppler show. The aim of this review is to explain the physical principles behind the medical Doppler ultrasound, also, to use some of the mathematical formulas utilized in the medical Doppler ultrasound examination...
January 2018: Journal of Medical Ultrasound
https://www.readbyqxmd.com/read/30064156/visceral-adiosity-index-as-a-useful-tool-for-the-assessment-of-cardiometabolic-disease-risk-in-women-aged-65-74-living-in-central-poland
#14
Tadeusz Dereziński, Dorota Zozulińska-Ziółkiewicz, Aleksandra Uruska, Mariusz Dąbrowski
BACKGROUND: The Visceral Adiposity Index (VAI) is considered to be a reliable indicator of adipose tissue dysfunction and cardiometabolic disease risk. The aim of this study was to evaluate its usefulness in assessing cardiometabolic risk in a sample of elderly women living in a rural-urban community in central Poland. METHODS: A total of 365 women aged 65-74 years were included in this cross-sectional study. All patients were interviewed to obtain their history of diabetes mellitus, myocardial infarction, stroke and revascularization...
July 31, 2018: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/30058080/acute-cardiovascular-adaptation-to-strenuous-exercise-an-integrative-ultrasound-study
#15
Elisabetta Bianchini, Rosa Maria Bruno, Nicole Di Lascio, Alessandra Vezzoli, Simona Mrakic-Sposta, Anca Irina Corciu, Mario Comassi, Lorenza Pratali
OBJECTIVES: The aim of this study was to evaluate the acute effects of participation in an Ironman distance triathlon competition on arterial function by ultrasound, in relation to cardiac function and body water content. METHODS: Twenty-eight male triathletes participating in an Ironman distance competition underwent carotid, femoral, and cardiac ultrasound examinations. Moreover, the presence of extravascular lung water was identified by lung echo B-lines (echogenic coherent wedge-shaped signal with a narrow origin from the hyperechoic pleural line) at rest and within 20 minutes of arrival...
July 29, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/30055051/new-insights-into-arterial-baroreflex-function-during-acute-exercise-role-of-central-angiotensin-ii
#16
Kamila U Migdal, Austin T Robinson
The arterial baroreceptors, originating in the carotid bodies and aorta, are important in the rapid regulation of the cardiovascular system, buffering short-term changes in arterial blood pressure (BP). Beat-to-beat increases and decreases in BP cause conformational changes in the arterial baroreceptors, ultimately leading to changes in sympathetic efferent neuronal firing. During exercise, the arterial baroreflex resets in an intensity-dependent manner, enabling parallel increases in BP and heart rate (HR) to facilitate an increase in cardiac output...
July 28, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/30054892/wideband-external-pulse-recorded-during-cuff-blood-pressure-measurement-a-new-technique-for-cardiovascular-assessment
#17
Seymour G Blank, Gary D James, Mary J Roman
INTRODUCTION: The wideband external pulse (WEP) recorded during blood pressure measurement reveals three components (K1, K2, K3). K1 is recorded with cuff pressure (CP) above systolic (SP). AIM: To assess whether the K1 pattern contains information about the functional and structural properties of the cardiovascular system. METHODS: WEP analysis, echocardiography, carotid artery (CA) ultrasonography and applanation tonometry were conducted on 178 hypertensives...
July 27, 2018: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/30052805/testosterone-to-estradiol-ratio-reflects-systemic-and-plaque-inflammation-and-predicts-future-cardiovascular-events-in-men-with-severe-atherosclerosis
#18
Ian D van Koeverden, Marie de Bakker, Saskia Haitjema, Sander W van der Laan, Jean-Paul P M de Vries, Imo E Hoefer, Gert J de Borst, Gerard Pasterkamp, Hester M den Ruijter
Aims: The effects of testosterone on cardiovascular disease (CVD) as reported in literature have been ambiguous. Recently, the interplay between testosterone and estradiol as assessed by testosterone/estradiol (T/E2) ratio was suggested to be better informative on the normal physiological balance. Considering the role in CVD, we hypothesized that a low T/E2 ratio in men with CVD is associated with increased inflammation, a more unstable plaque and a worse cardiovascular outcome. Methods and results: Testosterone and estradiol concentrations were determined in blood samples of 611 male carotid endarterectomy patients included in the Athero-Express Biobank Study...
July 20, 2018: Cardiovascular Research
https://www.readbyqxmd.com/read/30051384/wave-intensity-analysis-sex-specific-differences-in-hemodynamic-and-ventilatory-responses-to-graded-exercise-echocardiographic-measurements
#19
Midori Tanaka, Motoaki Sugawara, Yasuo Ogasawara, Kiyomi Niki
BACKGROUND: The differences in hemodynamic and ventilatory responses to graded exercise between men and women have not been well documented. Using wave intensity (WI) analysis, which is useful for analyzing ventriculo-arterial interaction, we aimed to elucidate the sex-specific differences. METHODS: We enrolled 48 healthy subjects (24 men and 24 women, age 21.3 ± 1.6 and 20.5 ± 0.9 years, n.s. [not significant]). Using ultrasonic diagnostic equipment, we measured WI, arterial stiffness parameter (β), force-frequency relation (FFR) and other hemodynamic parameters in the carotid artery before and during graded bicycle exercise...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/30050461/contribution-of-oxidative-stress-and-inflammation-to-the-neurogenic-hypertension-induced-by-intermittent-hypoxia
#20
REVIEW
María P Oyarce, Rodrigo Iturriaga
Chronic intermittent hypoxia (CIH), the hallmark of obstructive sleep apnea, is the main risk factor to develop systemic hypertension. Oxidative stress, inflammation, and sympathetic overflow have been proposed as possible mechanisms underlying the CIH-induced hypertension. CIH potentiates the carotid body (CB) chemosensory discharge leading to sympathetic overflow, autonomic dysfunction, and hypertension. Oxidative stress and pro-inflammatory molecules are involved in neurogenic models of hypertension, acting on brainstem and hypothalamic nuclei related to the cardiorespiratory control, such as the nucleus of the solitary tract, which is the primary site for the afferent inputs from the CB...
2018: Frontiers in Physiology
keyword
keyword
162701
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"