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Lateral lymph node dissection

Jeffrey P Gross, Sean Sachdev, Irene B Helenowski, David Lipps, John P Hayes, Eric D Donnelly, Jonathan B Strauss
PURPOSE: The occurrence of upper extremity lymphedema after regional nodal irradiation (RNI) for breast cancer treatment varies significantly based on patient and treatment factors. The relationship between the radiation therapy (RT) field design and lymphedema risk is not well-characterized. The present study sought to correlate the variations in RT field design with lymphedema outcomes. METHODS AND MATERIALS: Women with stage II-IV breast cancer receiving RNI after breast surgery that included sentinel lymph node biopsy or axillary dissection were identified...
September 1, 2018: International Journal of Radiation Oncology, Biology, Physics
Arkadiusz P Wysocki, Skyle Murphy, Ingrid Baade
Introduction Expert opinion recommends that surgeons perform a laparoscopic cholecystectomy (LC) in a standardized manner by dissecting the hepatobiliary triangle lateral to the cystic artery lymph node (LN) to minimize the rate of a major bile duct injury. Methods To determine whether surgeons performed a laparoscopic cholecystectomy in a standardized manner, the study assessed the variability in the frequency of an LN excision. All LCs that were performed at a single hospital were identified from a prospective dataset...
June 7, 2018: Curēus
Songphol Malakorn, Akira Ouchi, Tarik Sammour, Brian K Bednarski, George J Chang
No abstract text is available yet for this article.
September 2018: Diseases of the Colon and Rectum
Xi Zhang, Li Zhang, Shuai Xue, Peisong Wang, Guang Chen
BACKGROUND: Solitary papillary thyroid microcarcinoma (PTMC) without gross extrathyroidal extension (ETE) were the main candidates for active surveillance (AS). Predictive factors of lateral lymph node metastasis (LLNM) in solitary PTMC without gross ETE were essential but still unknown. METHODS: Altogether, 171 patients of solitary PTMC without gross ETE were enrolled in our study and divided into two groups. Group A: 123 patients without lateral lymph node dissection (LLND) were considered to be LLNM negative because there was no lateral recurrence by at least 8-year follow up for all patients...
August 3, 2018: Asian Journal of Surgery
Takashi Iguchi, Shimpei Yamashita, Satoshi Nishizawa, Akinori Iba, Yasuo Kohjimoto, Isao Hara
A 51-year-old man visited our hospital since he had noticed remarkable increase in size of left scrotal contents. Computed tomography revealed left testicular swelling, retroperitoneal, pelvic and left inguinal lymph nodes. Serum testicular tumor markers (α fetoprotein, β-human chorionic gonadotropin, lactate dehydrogenase) were elevated. Low left orchiectomy was performed due to swelling of the left inguinal lymph node. The excised specimen weighed 3,400g. Pathological findings were non-seminoma. Although there was no operation history of scrotal groin, there was metastasis in the left inguinal lymph node ; therefore, the stage of disease was T2N3M1a...
June 2018: Hinyokika Kiyo. Acta Urologica Japonica
Mitsuhiro Katagiri, Keisuke Miwa, Susumu Shimomura, Takatou Yomoda, Kensuke Tajiri, Sachiko Nagasu, Shinya Fujino, Kenichi Koushi, Fumihiko Fujita, Tetsushi Kinugasa, Yoshito Akagi
The case involved a 44-year-old man who underwent intersphincteric resection and lateral lymph node dissection for rectal cancer. Pathological diagnosis revealed a well-differentiated adenocarcinoma comprising KRAS wild type, and pT2N0M0 (pathological Stage I). CapeOX (capecitabine plus oxaliplatin[L-OHP]), and bevacizumab therapy was initiated because of local recurrence. Although a partial response (PR) was observed, the therapy was terminated after 6 courses because of the development of hand-foot syndrome...
May 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Jehan Belal Yahya, Daniel O Herzig, Matthew Joseph Farrell, Catherine R Degnin, Yiyi Chen, John Holland, Simon Brown, Jerry Jaboin, Vassiliki Liana Tsikitis, Kim Lu, Charles R Thomas, Timur Mitin
Background: Management of rectal cancer with involved lateral pelvic lymph nodes (LPLNs) at the time of diagnosis-the stage we refer institutionally to as Stage 3.5-is controversial. The American Joint Committee on Cancer's 7th edition classifies internal iliac lymph nodes (LNs) as regional (Stage III), but both external and common iliac LNs as metastatic (Stage IV). However, in many Asian countries all LPLNs are considered regional and patients are treated with curative intent, with literature supporting improved outcomes with LPLN dissection...
June 2018: Journal of Gastrointestinal Oncology
Aeris Jane D Nacion, Youn Young Park, Seung Yoon Yang, Nam Kyu Kim
Despite innovative advancements, the management of distally located rectal cancer (RC) remains a formidable endeavor. The critical location of the tumor predisposes it to a circumferential resection margin that tends to involve the sphincters and surrounding organs, pelvic lymph node metastasis, and anastomotic complications. In this regard, colorectal surgeons should be aware of issues beyond the performance of total mesorectal excision (TME). For decades, abdominoperineal resection had been the standard of care for low-lying RC; however, its association with high rates of tumor recurrence, tumor perforation, and poorer survival has stimulated the development of novel surgical techniques and modifications, such as extralevator abdominoperineal excision...
August 2018: Yonsei Medical Journal
Tsutomu Namikawa, Nobuko Ishida, Sachi Tsuda, Kazune Fujisawa, Eri Munekage, Jun Iwabu, Masaya Munekage, Sunao Uemura, Shigehiro Tsujii, Hiromichi Maeda, Hiroyuki Kitagawa, Michiya Kobayashi, Kazuhiro Hanazaki
BACKGROUND: Although a recent randomized clinical trial has demonstrated that the objective response rate to nivolumab for metastatic gastric cancer was 11.2%, there was no patients confirmed complete response. Herein, we report on a case of liver metastasis arising from early gastric cancer in which a complete clinical response was achieved to nivolumab as third-line therapy. CASE PRESENTATION: A 77-year-old man was referred to Kochi Medical School Hospital for the treatment of liver metastases from gastric cancer...
July 5, 2018: Surgical Case Reports
Taha Numan Yıkılmaz, Erdem Öztürk, Nurullah Hamidi, Halil Başar, Önder Yaman
OBJECTIVE: Obturator nerve injuries may be seen during pelvic lymph node dissection in oncological surgery and although not common it is an important complication. According to the shape and location of the injury, tingling and loss of sensation may develop on the inner surface of the leg, together with loss of motor function of the adductor muscles. In this study an evaluation was made of these complications encountered in our clinic and the management strategies applied to these patients...
May 21, 2018: Turkish Journal of Urology
Soichiro Ishihara, Kazushige Kawai, Toshiaki Tanaka, Keisuke Hata, Hiroaki Nozawa
BACKGROUND: Lateral pelvic lymph node (LLN) dissection is suggested to improve the prognosis of rectal cancer patients; however, accurate diagnosis of LLN metastasis is challenging, especially after preoperative chemoradiotherapy (CRT). The aim of this study was to clarify the diagnostic value of LLN size in rectal cancer patients treated with CRT in terms of metastasis. METHODS: A total of 204 LLNs dissected from 29 rectal cancer patients treated with CRT were examined...
July 5, 2018: ANZ Journal of Surgery
Bobo Zheng, Nan Wang, Tao Wu, Qing Qiao, Li Gong, Shuai Zhou, Bo Zhang, Ying Yang, Ke Wang, Yulong Zhai, Xianli He
OBJECTIVE: To investigate the application value of the clearance of No.253 lymph nodes with priority to fascial space and preserving left colic artery (LCA) in patients undergoing laparoscopic radical proctectomy. METHODS: From August 2015 to August 2016, 97 consecutive middle-low rectal cancer patients underwent laparoscopic radical proctectomy using the clearance of No.253 lymph nodes with priority to fascial space and preserving LCA at Department of General Surgery, Tangdu Hospital...
June 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Nelson N Stone, Richard G Stock
To report the long-term results of prostate brachytherapy followed by external beam irradiation (EBRT) in men with a positive seminal vesicle biopsy (+SVB). Materials and Methods 1981 men with localized prostate cancer were treated with permanent brachytherapy of which 615 had staging SVB and 53 (9.4%) were positive. Higher stage, Gleason score and PSA were associated with a positive SVB (p<0.001). Patients with +SVB and negative laparoscopic pelvic lymph node dissection, bone and CT scans had 3 months of androgen deprivation therapy (ADT) followed by Pd-103 implant to the prostate (dose 100 Gy) and proximal SVs and 2 months later 45 Gy EBRT...
June 29, 2018: BJU International
Kazushige Kawai, Teppei Morikawa
PURPOSE: Although several studies have demonstrated that the size of harvested lymph nodes can be a prognostic predictor in colorectal cancer patients, some considered the size of freshly harvested nodes and others assessed the size after formalin fixation. Because the size change of lymph nodes during fixation has not been fully investigated, we conducted the present study comparing the size of lateral lymph nodes that were surgically harvested from rectal cancer patients, before and after formalin fixation...
June 21, 2018: International Journal of Colorectal Disease
T Zhang, Y Qu, L He, L Shao, D L Zhang, C Z Lü, P Zhang, H Zhang
Objective: To investigate the risk factors and preoperative evaluation of lymph nodes posterior to right recurrent laryngeal nerve (LN-prRLN) metastasis in papillary thyroid carcinoma (PTC). Methods: Clinical data of 301 patients with right or double lobes who underwent surgery between August 2015 and October 2016 in the Department of Thyroid Surgery, the First Hospital of China Medical University, were retrospectively analyzed. The relationships between LN-prRLN metastasis and clinical pathology data and other factors were analyzed...
June 12, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Kazushige Kawai, Keisuke Hata, Toshiaki Tanaka, Takeshi Nishikawa, Kensuke Otani, Koji Murono, Kazuhito Sasaki, Manabu Kaneko, Shigenobu Emoto, Hiroaki Nozawa
OBJECTIVE: This study aimed to assess the learning curve of robotic rectal surgery, a procedure that has gained increasing focus in recent years because it is expected that the advanced devices used in this approach provide advantages resulting in a shorter learning curve than that of laparoscopic surgery. However, no studies have assessed the learning curve of robotic rectal surgery, especially when lateral lymph node dissection is required. DESIGN: This was a nonrandomized, retrospective study from a single institution...
June 12, 2018: Journal of Surgical Education
Yuki Aisu, Shigeru Kato, Yoshio Kadokawa, Daiki Yasukawa, Yusuke Kimura, Yuichi Takamatsu, Taku Kitano, Tomohide Hori
BACKGROUND The feasibility of additional dissection of the lateral pelvic lymph nodes (LPLNs) in patients undergoing total mesorectal excision (TME) combined with neoadjuvant chemotherapy (NAC) for locally advanced rectal cancer (LARC) is controversial. The use of laparoscopic surgery is also debated. In the present study, we evaluated the utility of laparoscopic dissection of LPLNs during TME for patients with LARC and metastatic LPLNs after NAC, based on our experience with 19 cases. MATERIAL AND METHODS Twenty-five patients with LARC with swollen LPLNs who underwent laparoscopic TME and LPLN dissection were enrolled in this pilot study...
June 11, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Kapil Dev, K V Veerenderkumar, Swamyvelu Krishnamurthy
The lateral pelvic lymph node recurrence after curative resection in rectal cancer has been reported in more than 20% of cases and the lateral pelvic lymph node (LPLN) metastasis is an independent risk factor for local recurrence. A prospective cohort study with diagnosis of lower rectal cancer stages II and III performed to identify the factors with significant correlation with LPLN metastasis was categorised based on the number of positive factors and proposed a risk stratification model to uncover a possible benefit of LPLD in specific patient subgroups...
June 2018: Indian Journal of Surgical Oncology
Takeru Matsuda, Kimihiro Yamashita, Hiroshi Hasegawa, Taro Oshikiri, Masayoshi Hosono, Nobuhide Higashino, Masashi Yamamoto, Yoshiko Matsuda, Shingo Kanaji, Tetsu Nakamura, Satoshi Suzuki, Yasuo Sumi, Yoshihiro Kakeji
Because of recent advances in medical technology and new findings of clinical trials, treatment options for colorectal cancer are evolutionally changing, even in the last few years. Therefore, we need to update the treatment options and strategies so that patients can receive optimal and tailored treatment. The present review aimed to elucidate the recent global trends and update the surgical treatment strategies in colorectal cancer by citing the literature published in the last 2 years, namely 2016 and 2017...
March 2018: Annals of gastroenterological surgery
Takahide Shinagawa, Toshiaki Tanaka, Hiroaki Nozawa, Shigenobu Emoto, Koji Murono, Manabu Kaneko, Kazuhito Sasaki, Kensuke Otani, Takeshi Nishikawa, Keisuke Hata, Kazushige Kawai, Toshiaki Watanabe
Colorectal cancer (CRC) is one of the most common cancers globally as well as in Japan and has shown a pattern of increasing incidence and mortality rates. Therefore, guidelines for CRC are considered to be crucial for establishing standard medical treatment not only in Japan but also around the world. In this article, we explain the features of the representative guidelines in Japan (Japanese Society for Cancer of the Colon and Rectum [JSCCR]), the USA (National Comprehensive Cancer Network [NCCN]) and Europe (European Society for Medical Oncology [ESMO]) and review the differences among these guidelines for CRC...
January 2018: Annals of gastroenterological surgery
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