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https://www.readbyqxmd.com/read/30512990/effects-of-obesity-and-exercise-on-colon-cancer-induction-and-hematopoiesis-in-mice
#1
Russell Emmons, Guanying Xu, Diego Hernandez-Saavedra, Adam Kriska, Yuan-Xiang Pan, Hong Chen, Michael De Lisio
Obesity-induced inflammation associated with increased risk for colorectal cancer (CRC). The role of diet and exercise in modulating increased CRC risk in obesity, and the potential role of altered hematopoiesis as a contributor to these effects remain unknown. The purpose of this study was to examine how weight loss induced during CRC induction with or without exercise alter CRC initiation and their relationship to altered hematopoiesis. Mice consumed either a control (CON) or high fat diet to induce obesity...
December 4, 2018: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30501480/effects-of-guided-reflection-on-diabetes-self-care-a-randomized-controlled-trial
#2
Jennifer A Fearon-Lynch, Kristen A Sethares, Marilyn E Asselin, Kristine Batty, Caitlin M Stover
The purpose of this study was to evaluate the effects of guided reflection on self-care behaviors, confidence scores, and diabetes knowledge among adults with diabetes. A randomized controlled trial with a pre/posttest design was used to generate data from a convenience sample of 62 adults with diabetes recruited from a single site. After viewing a 30-minute video on how to manage diabetes, participants were randomized to a control group (CG) (usual care) or an intervention group (IG). The IG further engaged in a reflection educational session...
December 3, 2018: Diabetes Educator
https://www.readbyqxmd.com/read/30498836/pre-frail-80-multifactorial-intervention-to-prevent-progression-of-pre-frailty-to-frailty-in-the-elderly
#3
L Gené Huguet, M Navarro González, B Kostov, M Ortega Carmona, C Colungo Francia, M Carpallo Nieto, A Hervás Docón, R Vilarrasa Sauquet, R García Prado, A Sisó-Almirall
OBJECTIVES: Preventing or delaying frailty has important benefits in the elderly, and in health and social services. Studies have demonstrated the effectiveness of multifactorial interventions in the frail elderly, but there are fewer studies on community-dwelling pre-frail individuals. Identifying pre-frail individuals susceptible to intervention could prevent or delay frailty and its consequences and associated disability and might reverse the state from pre-frail to robust. To evaluate a multifactorial, interdisciplinary primary care intervention in community-dwelling pre-frail elderly patients aged ≥ 80 years...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/30470803/the-effect-of-a-very-low-calorie-diet-on-subjective-depressive-symptoms-and-anxiety-meta-analysis-and-systematic-review
#4
REVIEW
Natalie Ein, Bonnie Armstrong, Kristin Vickers
There are conflicting findings regarding the effect very low calorie diets (VLCDs) have on self-reported depressive symptoms and anxiety levels. Some studies have reported decreased subjective depressive symptoms and anxiety post-diet, whereas other studies have not. Further complicating matters, the protocol for VLCDs vary substantially across studies, which could account for the mixed findings. The primary goal of this meta-analysis and systematic review was to determine the effect VLCDs have on subjective depressive symptoms and anxiety pre- to post-diet...
November 23, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/30465443/exercise-augments-the-modulatory-effects-of-vitamin-e-on-pre-diabetes-induced-aortopathy-a-potential-role-of-adiponectin
#5
Mohammad A Dallak, Bahjat Al-Ani, Abbas O El Karib, Mohamed Abd Ellatif, Refaat A Eid, Rihab Al-Ani, Hesham M Mahmoud, Mohamed A Haidara
BACKGROUND: We tested the hypothesis that vitamin E may protect against pre-diabetes-induced aortic injury (aortopathy), and exercise can augment the action of vitamin E. MATERIAL AND METHODS: Rats were either fed with a high fat and fructose diet (HFD) (model group) or a standard laboratory chow (control group) for 15 weeks before being sacrificed. The three protective groups were treated with vitamin E (HFD + Vit E), swimming exercises (HFD + Ex), and vitamin E plus swimming exercises (HFD + VitE + Ex), respectively...
November 22, 2018: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/30456780/effects-of-a-topical-lotion-containing-aminophylline-caffeine-yohimbe-l-carnitine-and-gotu-kola-on-thigh-circumference-skinfold-thickness-and-fat-mass-in-sedentary-females
#6
Guillermo Escalante, Patrick Bryan, Juan Rodriguez
BACKGROUND AND OBJECTIVE: Topical aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola (Centella asiatica) may aid in reducing body fat. Lipoxyderm™ contains these ingredients and was used to test if fat loss of the thigh, in conjunction with a low intensity exercise program and restricted calorie intake, was enhanced via the topical application of this lotion. METHODS: This was a double-blind, placebo-controlled, within-group study that investigated the effects of Lipoxyderm™ on thigh fat mass, circumference, and skinfold thickness...
November 19, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/30357446/inhibition-of-osteocyte-membrane-repair-activity-via-dietary-vitamin-e-deprivation-impairs-osteocyte-survival
#7
Mackenzie L Hagan, Anoosh Bahraini, Jessica L Pierce, Sarah M Bass, Kanglun Yu, Ranya Elsayed, Mohammed Elsalanty, Maribeth H Johnson, Anna McNeil, Paul L McNeil, Meghan E McGee-Lawrence
Osteocytes experience plasma membrane disruptions (PMD) that initiate mechanotransduction both in vitro and in vivo in response to mechanical loading, suggesting that osteocytes use PMD to sense and adapt to mechanical stimuli. PMD repair is crucial for cell survival; antioxidants (e.g., alpha-tocopherol, also known as Vitamin E) promote repair while reactive oxygen species (ROS), which can accumulate during exercise, inhibit repair. The goal of this study was to determine whether depleting Vitamin E in the diet would impact osteocyte survival and bone adaptation with loading...
October 24, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/30356640/what-is-the-most-effective-exercise-protocol-to-improve-cardiovascular-fitness-in-overweight-and-obese-subjects
#8
Eliane Aparecida Castro, Ana Belén Peinado, Pedro Jose Benito, Mercedes Galindo, Marcela González-Gross, Rocío Cupeiro
Background: Increased peak oxygen consumption (VO2peak ) can reduce cardiovascular risks associated with obesity. Our aim was to analyze the effect of a weight loss program on cardiovascular fitness in overweight (W) and obese (O) subjects. Methods: One hundred and sixty-seven subjects (77 males and 90 females), aged 18-50 years, performed a modified Bruce protocol before (pre) and after (post) a weight loss program of 24 weeks. This program combined physical training (strength, S; endurance, E; combined strength + endurance, SE; or physical activity recommendation, PA) 3 times per week, with a 25%-30% caloric restriction diet...
December 2017: Journal of Sport and Health Science
https://www.readbyqxmd.com/read/30341593/adaptations-to-concurrent-training-in-combination-with-high-protein-availability-a-comparative-trial-in-healthy-recreationally-active-men
#9
Baubak Shamim, Brooke L Devlin, Ryan G Timmins, Paul Tofari, Connor Lee Dow, Vernon G Coffey, John A Hawley, Donny M Camera
BACKGROUND: We implemented a high-protein diet (2 g·kg-1 ·d-1 ) throughout 12 weeks of concurrent exercise training to determine whether interferences to adaptation in muscle hypertrophy, strength and power could be attenuated compared to resistance training alone. METHODS: Thirty-two recreationally active males (age: 25 ± 5 years, body mass index: 24 ± 3 kg·m-2 ; mean ± SD) performed 12 weeks of either isolated resistance (RES; n = 10) or endurance (END; n = 10) training (three sessions·w-1 ), or concurrent resistance and endurance (CET; n = 12) training (six sessions·w-1 )...
December 2018: Sports Medicine
https://www.readbyqxmd.com/read/30306296/non-alcoholic-fatty-liver-disease-and-obesity-the-role-of-the-gut-bacteria
#10
REVIEW
Katherine J P Schwenger, Colin M Bolzon, Carrie Li, Johane P Allard
Non-alcoholic fatty-liver disease (NAFLD) is now considered one of the leading causes of liver disease worldwide and is associated with metabolic syndrome and obesity. There are several factors contributing to the disease state. Recent research suggests that the intestinal microbiota (IM) and bacterial products may play a role through several mechanisms which include increased energy uptake, intestinal permeability and chronic inflammation. In addition to diet and exercise, treatment options targeting the IM are being investigated and include the use of pre-, pro- and synbiotics as well as the possibility of fecal microbial transfers...
October 10, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/30284241/a-pilot-study-of-cardiopulmonary-exercise-testing-and-cardiac-stress-positron-emission-tomography-before-major-non-cardiac-surgery
#11
M T Ferguson, M S Hofman, H Ismail, A Melville, K S K Yap, R J Hicks, S Wright, B Riedel
Cardiac events are a common cause of peri-operative morbidity. Cardiopulmonary exercise testing can objectively assess risk, but it does not quantify myocardial ischaemia. With appropriate dietary preparation to suppress basal myocardial glucose uptake, positron emission tomography with 18 F-fluorodeoxyglucose can identify post-ischaemic myocardium, providing an attractive complement to exercise testing. We aimed to investigate the feasibility of this diagnostic algorithm. Patients referred for cardiopulmonary exercise testing before major cancer surgery were prospectively recruited...
October 3, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30254498/preview-study-influence-of-a-behavior-modification-intervention-premit-in-over-2300-people-with-pre-diabetes-intention-self-efficacy-and-outcome-expectancies-during-the-early-phase-of-a-lifestyle-intervention
#12
Maija Huttunen-Lenz, Sylvia Hansen, Pia Christensen, Thomas Meinert Larsen, Finn Sandø-Pedersen, Mathijs Drummen, Tanja C Adam, Ian A Macdonald, Moira A Taylor, J Alfredo Martinez, Santiago Navas-Carretero, Svetoslav Handjiev, Sally D Poppitt, Marta P Silvestre, Mikael Fogelholm, Kirsi H Pietiläinen, Jennie Brand-Miller, Agnes Am Berendsen, Anne Raben, Wolfgang Schlicht
Purpose: Onset of type 2 diabetes (T2D) is often gradual and preceded by impaired glucose homeostasis. Lifestyle interventions including weight loss and physical activity may reduce the risk of developing T2D, but adherence to a lifestyle change is challenging. As part of an international T2D prevention trial (PREVIEW), a behavior change intervention supported participants in achieving a healthier diet and physically active lifestyle. Here, our aim was to explore the influence of this behavioral program (PREMIT) on social-cognitive variables during an 8-week weight loss phase...
2018: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/30242237/protein-synthesis-signaling-in-skeletal-muscle-is-refractory-to-whey-protein-ingestion-during-a-severe-energy-deficit-evoked-by-prolonged-exercise-and-caloric-restriction
#13
Marcos Martin-Rincon, Ismael Perez-Suarez, Alberto Pérez-López, Jesús Gustavo Ponce-González, David Morales-Alamo, Pedro de Pablos-Velasco, Hans-Christer Holmberg, Jose A L Calbet
BACKGROUND: Exercise and protein ingestion preserve muscle mass during moderate energy deficits. OBJECTIVE: To determine the molecular mechanisms by which exercise and protein ingestion may spare muscle mass during severe energy deficit (5500 kcal/day). DESIGN: Fifteen overweight, but otherwise healthy men, underwent a pre-test (PRE), caloric restriction (3.2 kcals/kg body weight/day) + exercise (45 min one-arm cranking + 8 h walking) for 4 days (CRE), followed by a control diet (CD) for 3 days, with a caloric content similar to pre-intervention while exercise was reduced to less than 10,000 steps per day...
September 21, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/30232854/-acupuncture-treatment-reduces-body-weight-possibly-by-down-regulating-insulin-and-leptin-resistance-and-up-regulating-soluble-leptin-receptor-level-in-prediabetic-patients
#14
Zhi-Ming Zhao, Chun-Li Liu, Qun-Yan Zhang, Bei-Bei Zhang, Jun-Hao Guo, Ai-Hong Yuan, Hui Cai
OBJECTIVE: To observe the effect of acupuncture of Feishu (BL 13), Pishu (BL 20), etc. on body weight, blood lipid, leptin (LP) and soluble leptin receptor (sOB-R) levels in prediabetic patients, so as to explore its mechanisms underlying treatment and prevention of prediabetes. METHODS: A total of 100 prediabetic patients were randomly assigned to medication (Metformin) group ( n =35), acupuncture group ( n =35) and simple lifestyle intervention group ( n =30) with random number table method...
August 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/30199540/effects-of-four-weeks-intermittent-hypoxia-intervention-on-glucose-homeostasis-insulin-sensitivity-glut4-translocation-insulin-receptor-phosphorylation-and-akt-activity-in-skeletal-muscle-of-obese-mice-with-type-2-diabetes
#15
Yun Wang, Li Wen, Shi Zhou, Yong Zhang, Xin-Hao Wang, You-Yu He, Allan Davie, Suzanne Broadbent
AIMS: The aims of this study were to determine the effects of four weeks of intermittent exposure to a moderate hypoxia environment (15% oxygen), and compare with the effects of exercise in normoxia or hypoxia, on glucose homeostasis, insulin sensitivity, GLUT4 translocation, insulin receptor phosphorylation, Akt-dependent GSK3 phosphorylation and Akt activity in skeletal muscle of obese mice with type 2 diabetes. METHODS: C57BL/6J mice that developed type 2 diabetes with a high-fat-diet (55% fat) (fasting blood glucose, FBG = 13...
2018: PloS One
https://www.readbyqxmd.com/read/30193589/a-systematic-search-and-qualitative-review-of-reporting-bias-of-lifestyle-interventions-in-randomized-controlled-trials-of-diabetes-prevention-and-management
#16
Natalie D Riediger, Andrea E Bombak, Adriana Mudryj, Jackson Bensley, Samuel Ankomah
BACKGROUND: Scholars have documented presumptions regarding the relationships between diet, exercise, weight, and type 2 diabetes. However, it is unclear to what extent researchers contribute to these presumptions, and how often these relationships are thoroughly delineated within the context of randomized controlled trials (RCTs). Thus, the aim was to conduct a systematic search and qualitative, thematic analysis of RCTs focusing on lifestyle interventions for diabetes prevention or management, to examine how researchers discuss body weight in 1) the rationale and design of their RCTs; and 2) their presentation and interpretation of their findings...
September 7, 2018: Nutrition Journal
https://www.readbyqxmd.com/read/30181005/-consensus-approach-prior-to-the-construction-of-an-evaluation-scale-of-risk-constipation-patients-hospitalized-for-nursing-practice
#17
V Berger, C Germain, R Lacomère, C Bader, O Gerbouin, A Bénard
BACKGROUND: Constipation is a frequent issue during hospitalization. Multiple causes such as the existence of irregular habits, lack of exercise as well as medical history have been identified. Drugs such as strong painkillers, central nervous system therapies and treatments of the digestive tract are a major cause of constipation. Additionally, unbalanced diet, fluid deficiency, and anxiety may aggravate constipation. The consideration of all these risk factors being under the responsibility of nurses...
September 2018: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/30172252/exercise-without-dietary-changes-alleviates-nonalcoholic-fatty-liver-disease-without-weight-loss-benefits
#18
Duck-Pil Ok, Kangeun Ko, Ju Yong Bae
BACKGROUND: This study aimed to analyze the effect of exercise and/or dietary change on improvement of non-alcoholic fatty liver disease (NAFLD) in chronic high-fat diet (HFD)-induced obese mice. METHODS: Forty male C57BL/6 (8 weeks old) mice were divided into normal diet (CO, n = 8) and high-fat diet (HF, n = 32) groups. The HF group was fed with 60% fat chow for 16 weeks to induce obesity. After the obesity induction period, the HF group was subdivided into HFD + sedentary (n = 8), HFD + training (HFT, n = 8), dietary change to normal-diet + sedentary (HFND, n = 8), and dietary change to normal-diet + training (HFNDT, n = 8) groups, and the mice in the training groups underwent treadmill training for 8 weeks, 5 times per week, 40 min per day...
September 1, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/30109788/achieving-the-recommended-gestational-weight-gain-in-high-risk-versus-low-risk-pregnancies
#19
Yeela Ben Naftali, Irit Chermesh, Ido Solt, Yolanda Friedrich, Lior Lowenstein
BACKGROUND: Abnormal gestational weight gain (GWG) has been associated with adverse outcomes for mothers and their offspring. OBJECTIVES: To compare the achievement of recommended GWG and lifestyle factors in women with high-risk versus normal-risk pregnancies. METHODS: Pregnant women hospitalized in a gynecological and obstetrics department and pregnant women who arrived at a community clinic for a routine checkup were interviewed and completed questionnaires relating to weight gain and lifestyle factors (e...
July 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/30104186/a-remote-intervention-to-prevent-or-delay-cognitive-impairment-in-older-adults-design-recruitment-and-baseline-characteristics-of-the-virtual-cognitive-health-vc-health-study
#20
Nicholas Bott, Shefali Kumar, Caitlyn Krebs, Jordan M Glenn, Erica N Madero, Jessie L Juusola
BACKGROUND: A growing body of evidence supports the use of lifestyle interventions for preventing or delaying the onset of Alzheimer disease and other forms of dementia in at-risk individuals. The development of internet-delivered programs would increase the scalability and reach of these interventions, but requires validation to ensure similar effectiveness to brick-and-mortar options. OBJECTIVE: We describe the study design, recruitment process, and baseline participant characteristics of the sample in the Virtual Cognitive Health (VC Health) study...
August 13, 2018: JMIR Research Protocols
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