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https://www.readbyqxmd.com/read/30334228/moving-into-the-next-era-of-pet-myocardial-perfusion-imaging-introduction-of-novel-18-f-labeled-tracers
#1
REVIEW
Rudolf A Werner, Xinyu Chen, Steven P Rowe, Constantin Lapa, Mehrbod S Javadi, Takahiro Higuchi
The heart failure epidemic continues to rise with coronary artery disease as one of its main causes. Novel concepts for risk stratification to guide the referring cardiologist towards revascularization procedures are of significant value. Myocardial perfusion imaging using single-photon emission computed tomography (SPECT) agents has demonstrated high accuracy for the detection of clinically relevant stenoses. With positron emission tomography (PET) becoming more widely available, mainly due to its diagnostic performance in oncology, perfusion imaging with that modality is more practical than in the past and overcomes existing limitations of SPECT MPI...
October 17, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/30333058/obesity-alters-the-in-vivo-mechanical-response-and-biochemical-properties-of-cartilage-as-measured-by-mri
#2
Amber T Collins, Micaela L Kulvaranon, Hattie C Cutcliffe, Gangadhar M Utturkar, Wyatt A R Smith, Charles E Spritzer, Farshid Guilak, Louis E DeFrate
BACKGROUND: Obesity is a primary risk factor for the development of knee osteoarthritis (OA). However, there remains a lack of in vivo data on the influence of obesity on knee cartilage mechanics and composition. The purpose of this study was to determine the relationship between obesity and tibiofemoral cartilage properties. METHODS: Magnetic resonance images (3T) of cartilage geometry (double-echo steady-state) and T1rho relaxation of the knee were obtained in healthy subjects with a normal (n = 8) or high (n = 7) body mass index (BMI) before and immediately after treadmill walking...
October 17, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/30332549/high-intensity-interval-exercise-induces-greater-acute-changes-in-sleep-appetite-related-hormones-and-free-living-energy-intake-compared-to-moderate-intensity-continuous-exercise
#3
Penelope S Larsen, Frank Marino, Kerri Melehan, Kym J Guelfi, Rob Duffield, Melissa Skein
Compare the effect of high-intensity interval and moderate-intensity continuous exercise on sleep characteristics, appetite-related hormones and eating behaviour. 11 overweight, inactive men completed two consecutive nights of sleep assessments to determine baseline (BASE) sleep stages and arousals recorded by polysomnography (PSG). On separate afternoons (1400-1600h), participants completed a 30min exercise bout: 1) moderate-intensity continuous exercise (MICE; 60% V̇O2peak) or 2) high-intensity interval exercise (HIIE; 60s work at 100% V̇O2peak: 240s rest at 50% V̇O2peak), in a randomised order...
October 17, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/30332529/the-efficacy-of-frontline-near-peer-teaching-in-a-modern-medical-curriculum
#4
Charlotte H Harrison, Ahmad Elmansouri, William Parton, Matthew A Myers, Samuel Hall, Jonny R Stephens, Eleanor G Seaby, Scott Border
Within medical education a reduction in curriculum time for subjects, such as anatomy puts pressure on educators to ensure the same learning outcomes are conveyed in less time. This has the potential to impact negatively on student experience. Near-peer teaching (NPT) is often praised as an effective revision tool, but its use as a frontline teaching resource remains unreported. The study explores the potential for NPT to promote delivery of learning outcomes and maximize student experience within a neuroanatomy module for second year medical students...
October 17, 2018: Anatomical Sciences Education
https://www.readbyqxmd.com/read/30329052/community-based-interventions-for-prevention-of-type-2-diabetes-in-low-and-middle-income-countries-a-systematic-review
#5
Bishal Gyawali, Joakim Bloch, Abhinav Vaidya, Per Kallestrup
Type 2 diabetes is an increasing burden in low- and middle-income countries (LMICs). Knowledge of effective prevention programs in LMICs is thus important. The aim of this review was to establish an overview of studies evaluating the effectiveness of community-based interventions for prevention of Type 2 diabetes in LMICs. A literature review with searches in the databases using MEDLINE in Ovid (Ovid MEDLINE® In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily, Ovid MEDLINE and Version (R); Embase; PsycINFO; Global Health; and Google Scholar) between 1 January 2000 and 31 December 2015 was conducted...
October 16, 2018: Health Promotion International
https://www.readbyqxmd.com/read/30328169/does-exercise-during-pregnancy-impact-on-maternal-weight-gain-and-fetal-cardiac-function-a-randomized-controlled-study
#6
Maia Brik, Irene Fernández-Buhigas, Aránzazu Martin-Arias, Marina Vargas Terrones, Rubén Barakat, Belén Santacruz
OBJECTIVE: to evaluate differences in maternal weight gain and fetal cardiac function according to exercise during pregnancy METHODS: A randomized controlled trial was performed at Hospital de Torrejón, Madrid, including 120 pregnant women, allocated into Exercise Group (EG) and Control Group (CG). The primary outcome was maternal weight. Secondary outcomes included caesarean section, preterm delivery, induction of labor, birth weight and fetal cardiac function parameters. A sample size of 45 (90 both groups) was planned to detect differences in maternal weight gain of at least 1 Kg, with a power of >80% (>0...
October 17, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/30327403/cost-effectiveness-of-exercise-referral-schemes-enhanced-by-self-management-strategies-to-battle-sedentary-behaviour-in-older-adults-protocol-for-an-economic-evaluation-alongside-the-sitless-three-armed-pragmatic-randomised-controlled-trial
#7
Manuela Deidda, Laura Coll-Planas, Maria Giné-Garriga, Míriam Guerra-Balic, Marta Roqué I Figuls, Mark A Tully, Paolo Caserotti, Dietrich Rothenbacher, Antoni Salvà Casanovas, Frank Kee, Nicole E Blackburn, Jason J Wilson, Mathias Skjødt, Michael Denkinger, Katharina Wirth, Emma McIntosh
INTRODUCTION: Promoting physical activity (PA) and reducing sedentary behaviour (SB) may exert beneficial effects on the older adult population, improving behavioural, functional, health and psychosocial outcomes in addition to reducing health, social care and personal costs. This paper describes the planned economic evaluation of SITLESS, a multicountry three-armed pragmatic randomised controlled trial (RCT) which aims to assess the short-term and long-term effectiveness and cost-effectiveness of a complex intervention on SB and PA in community-dwelling older adults, based on exercise referral schemes enhanced by a group intervention providing self-management strategies to encourage lifestyle change...
October 15, 2018: BMJ Open
https://www.readbyqxmd.com/read/30325911/determinants-of-patients-preferring-complementary-and-alternative-medicine-attending-public-hospitals-in-lahore-pakistan
#8
Abdullah Hussain, Rohina Khizer Mufti, Maryam Shahid
OBJECTIVE: To find the frequency and determinants of patients preferring complementary and alternative medicine over registered medical doctors.. METHODS: This cross-sectional study was conducted at Services Hospital, Mayo Hospital and Jinnah Hospital in Lahore, Pakistan, from June 8 to August 20, 2017.A pre-tested self-administered questionnaire was used to collect data. SPSS 20 was used for data analysis. . RESULTS: Of the 385 subjects, 200(51...
June 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/30325889/spinal-manipulative-therapy-effects-in-autonomic-regulation-and-exercise-performance-in-recreational-healthy-athletes-a-randomized-controlled-trial
#9
Pedro L Valenzuela, Sara Pancorbo, Alejandro Lucia, Francisco Germain
STUDY DESIGN: Randomized, double blind, parallel groups, sham-controlled trial. OBJECTIVE: To analyse the acute effects of spinal manipulative therapy (SMT) on performance and autonomic modulation. SUMMARY OF BACKGROUND DATA: The use of SMT is progressively spreading from the clinical to the sporting context owing to its purported ergogenic effects. However, its effects remain unclear. METHODS: . 37 male recreational athletes (aged 37 ± 9 years) who had never received SMT were assigned to a sham (n = 19) or actual SMT group (n = 18)...
October 15, 2018: Spine
https://www.readbyqxmd.com/read/30325791/effects-of-prolonging-eccentric-phase-duration-in-parallel-back-squat-training-to-momentary-failure-on-muscle-cross-sectional-area-squat-one-repetition-maximum-and-performance-tests-in-university-soccer-players
#10
Keisuke Shibata, Kazuki Takizawa, Kazunori Nosaka, Masao Mizuno
Shibata, K, Takizawa, K, Nosaka, K, and Mizuno, M. Effects of prolonging eccentric phase duration in parallel back-squat training to momentary failure on muscle cross sectional area, squat one repetition maximum, and performance tests in university soccer players. J Strength Cond Res XX(X): 000-000, 2018-This study aimed to compare 2 squat training programs repeated until momentary failure with different eccentric phase duration (2 seconds vs. 4 seconds) on the changes in muscle cross-sectional area, squat 1 repetition maximum (1RM), squat jump (SJ), and countermovement jump (CMJ) height, agility (T-test), and Yo-Yo intermittent recovery test (YY-IR2)...
October 12, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/30325242/effects-of-match-play-and-training-on-circulating-s100b-concentration-in-professional-rugby-players
#11
Brendan O'Connell, Fiona Wilson, Noreen Boyle, Tom O'Dwyer, Karl Denvir, Garreth Farrell, Áine M Kelly
OBJECTIVES: Examine the effects of match play and a season of training on serum S100B concentration in male professional rugby players. To assess the influence of contact play, values were compared with age- and fitness-matched athletes not involved in a contact sport. METHODS: Over a 2-year period, blood samples were collected from 38 players in pre-season, end of season, and post-matches (within 2 h). A control group of rowers (n = 15) was assessed pre- and post-training...
October 16, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/30323770/high-intensity-interval-training-is-associated-with-alterations-in-blood-biomarkers-related-to-brain-injury
#12
Alex P Di Battista, Katherine A Moes, Maria Y Shiu, Michael G Hutchison, Nathan Churchill, Scott G Thomas, Shawn G Rhind
Purpose: Blood biomarkers are a useful tool to study concussion. However, their interpretation is complicated by a number of potential biological confounds, including exercise. This is particularly relevant in military and athletic settings where injury commonly occurs during physical exertion. The impact of high-intensity interval training (HIIT) on putative brain injury biomarkers remains under-examined. The purpose of this study was to observe the effects of HIIT on a panel of blood biomarkers associated with brain injury...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30322439/pulmonary-rehabilitation-reduces-emergency-admission-and-hospitalization-rates-of-patients-with-chronic-respiratory-diseases
#13
İpek Özmen, Elif Yıldırım, Murat Öztürk, Birsen Ocaklı, Reyhan Yıldız, Rüya Aydın, Meral Karakış, Özgür Yılmaz, Emine Aksoy
OBJECTIVES: Chronic respiratory diseases exert a global health burden with high health care costs, morbidity, and mortality. The aim of the present study was to investigate the effect of pulmonary rehabilitation (PR) on emergency admission and hospitalization rates of patients with chronic respiratory disease. MATERIALS AND METHODS: In this retrospective cohort study, hospitalization rates and emergency admissions of patients before (December 2014-December 2015) and after PR (January 2015-December 2016) were investigated...
September 13, 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/30321613/a-post-exercise-facilitation-of-executive-function-is-independent-of-aerobically-supported-metabolic-costs
#14
Matthew Heath, Andrea Petrella, Jonathan Blazevic, David Lim, Andre Pelletier, Glen Belfry
A single-bout of aerobic or resistance training facilitates executive function and is a benefit thought to be specific to exercise durations greater than 20minutes. We sought to determine whether an executive benefit is observed for a session as brief as 10-minutes, and whether distinct and participant-specific exercise intensities - and associated metabolic costs - influence the magnitude of the benefit. Participants completed exercise sessions - via cycle ergometer - at moderate (80% of lactate threshold [LT]), heavy (15% of the difference between LT and VO2 peak ) and very-heavy (50% of the difference between LT and VO2 peak ) intensities determined via an incremental ramp test to volitional exhaustion...
October 12, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/30320041/age-sex-and-weight-effects-on-lactate-and-leukocyte-response-to-exercise-in-children-and-adolescents
#15
Jen Jen Chen, Elizabeth Gendy, Sharon Leu, Frank Zaldivar, Pietro Gallassetti, Elieze Nussbaum, Dan Cooper, Shlomit Random-Aizik
Post-exercise leucocytosis has been found in children and adults in response to exercise. When normalized to the work performed, children demonstrate a lower lactate response to exercise than in adults. This study examines the association between leukocyte and lactate response in children following exercise. 148 healthy children participated in this study. Each subject performed a ramp exercise on a cycle ergometer followed by ten 2-minute bouts of constant work rate separated by 1-minute rest intervals. Lactate, leukocyte and leukocyte subtype levels were taken pre- and post-exercise...
2018: European journal of sports & exercise science
https://www.readbyqxmd.com/read/30319764/emerging-mechanisms-and-novel-applications-of-hydrogen-gas-therapy
#16
REVIEW
Nathanael Matei, Richard Camara, John H Zhang
Clinical and pre-clinical studies have reported a broad range of applications for hydrogen gas therapy. Classically, conventional antioxidant therapy is limited because it neutralizes both the detrimental and protective effects of reactive oxygen species. As a weak reducing agent, hydrogen gas avoids this paradox by reacting with strong oxidants while leaving other beneficial oxidants reactive. This review gathers a promising list of hydrogen gas applications that merit further mechanistic investigation and additional therapeutic trials...
July 2018: Medical Gas Research
https://www.readbyqxmd.com/read/30317013/safety-and-feasibility-of-high-speed-resistance-training-with-and-without-balance-exercises-for-knee-osteoarthritis-a-pilot-randomised-controlled-trial
#17
Levinger Pazit, Dunn Jeremy, Bifera Nancy, Butson Michael, Elias George, Keith D Hill
OBJECTIVES: People with knee osteoarthritis (OA) have increased risk of falling with impaired ability to rapidly respond and generate lower limb muscle power to arrest a fall. We examined the feasibility and safety of a high speed resistance training program with and without balance exercises. DESIGN: A randomised controlled pilot trial comparing pre and post 8 weeks intervention within 3 groups: control, high speed resistance training (HSRT), high speed resistance training plus balance exercises (HSRTB)...
October 3, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/30314547/development-and-evaluation-of-an-elective-course-that-incorporates-a-standard-medication-therapy-management-certificate-program
#18
Karleen Melody, Elizabeth M Harris, Anisha B Grover
BACKGROUND AND PURPOSE: To describe the development and evaluation of a medication therapy management (MTM) elective that incorporates a nationally recognized certificate training program (CTP) by assessing changes in perceived abilities and values among student pharmacists, knowledge of course material, and performance conducting MTM services. Student satisfaction with course content and delivery model was also evaluated. EDUCATIONAL ACTIVITY AND SETTING: University faculty developed a didactic elective course to provide third-professional year student pharmacists with the opportunity to meet the learning objectives of the American Pharmacists Association (APhA) "Delivering Medication Therapy Management Services" CTP...
August 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/30314542/interprofessional-education-through-a-telehealth-team-based-learning-exercise-focused-on-pharmacogenomics
#19
Kelly M Quesnelle, David R Bright, Lisa A Salvati
BACKGROUND: Traditional interprofessional educational (IPE) exercises are those where learning exists "about, from, and with" trainees in two or more professions in order to prepare health sciences professionals to work on interprofessional teams. One emerging difficulty with IPE is the paucity of health profession students at single institutions, and the geographic and financial constraints of multi-institutional collaboration. INTERPROFESSIONAL EDUCATION ACTIVITY: To circumvent these barriers, we developed a multi-institution telehealth team-based learning (TBL) event between medical and pharmacy students on the topic of pharmacogenomics (PGx)...
August 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/30311690/obstetric-fistula-the-role-of-physiotherapy-a-report-from-the-physiotherapy-committee-of-the-international-continence-society
#20
Gill Brook
AIMS: To discuss the role of physiotherapy in the management of women who have suffered an obstetric fistula, referring to research findings when appropriate and available, and the experiences of clinical specialists in the field. METHODS: The experiences of physiotherapists who have worked in countries where obstetric fistula is prevalent, and the limited literature available, were considered in producing this consensus document on behalf of the ICS Physiotherapy Committee...
October 12, 2018: Neurourology and Urodynamics
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