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https://www.readbyqxmd.com/read/30110686/whole-body-plethysmography-and-blood-gas-analysis-in-patients-with-acute-myocardial-infarction-undergoing-percutaneous-coronary-intervention
#1
Michael Dreher, Ayham Daher, András Keszei, Nikolaus Marx, Tobias Müller, Christian Cornelissen, Vincent Brandenburg
BACKGROUND: Chronic obstructive pulmonary disease (COPD) and coronary heart disease (CHD) often occur together. However, COPD is underdiagnosed among CHD patients. OBJECTIVES: This study investigated the prevalence of COPD and relevant pulmonary function test (PFT) impairments in patients with acute myocardial infarction (AMI). METHODS: Patients undergoing coronary angiography for AMI were prospectively included. Body plethysmography, lung diffusing capacity, blood gas analysis, and echocardiography were performed...
August 15, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/30110675/obstructive-sleep-apnea-increases-sudden-cardiac-death-in-incident-hemodialysis-patients
#2
Eric S Kerns, Esther D Kim, Lucy A Meoni, Stephen M Sozio, Bernard G Jaar, Michelle M Estrella, Rulan S Parekh, Ghada Bourjeily
BACKGROUND: Mortality in end-stage renal disease (ESRD) occurs predominantly from cardiovascular disease (CVD) and sudden cardiac death (SCD). Obstructive sleep apnea (OSA) is characterized by periodic airflow limitation associated with sleep arousal and oxygen desaturation and is prevalent in patients with ESRD. Whether OSA increases the risk for SCD, cardiovascular and all-cause mortality among hemodialysis patients remains unknown. METHODS: In a prospective cohort of 558 incident hemodialysis patients, we examined the association of OSA with all-cause mortality, cardiovascular mortality, and SCD using Cox proportional hazards models controlling for traditional CVD risk factors...
August 15, 2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/30110189/a-case-of-neurologically-intact-survival-after-2-hours-and-50-minutes-of-euthermic-cardiac-arrest-treated-with-mechanical-cpr-and-intra-arrest-percutaneous-coronary-intervention
#3
Aaron Michael Burnett, Ralph J Frascone, Johannes Brechtken, David Warren, Brian Roach, Andrew R Zinkel
We report a case of a 56 year old male in ventricular fibrillation (VF) cardiac arrest for a total of 2 hours and 50 minutes who was diagnosed with ST elevation myocardial infarction (STEMI) during a brief 10 min period of ROSC. The patient underwent successful percutaneous coronary intervention (PCI) while receiving mechanical chest compressions for ongoing VF. Our case demonstrates the potential for neurologically intact survival in VF cardiac arrest patients despite prolonged periods of VF who are treated with mechanical CPR and intra-arrest PCI...
August 15, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/30109863/the-utility-of-high-sensitivity-c-reactive-protein-levels-in-patients-with-moderate-coronary-lesions-and-gray-zone-fractional-flow-reserve
#4
Lin Li, Qi Wei Liu, Zhe Li, Li Wang, Jian Hong Wang, Lei Song, Bin Li
OBJECTIVE: It remains controversial whether patients with fractional flow reserve (FFR) values of 0.75-0.80 (gray-zone) should be treated with percutaneous coronary intervention (PCI). This study aimed to evaluate the prediction of high-sensitivity C-reactive protein (hs-CRP) levels to guide treatment selection in gray-zone patients. METHODS: This prospective interventional trial was conducted between January 2015 and March 2016. A total of 785 patients with stable angina and single-vessel stenosis with moderate coronary lesions were admitted to hospital in this period...
August 15, 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/30109827/prevention-of-cardiovascular-diseases-with-anti-inflammatory-and-anti-oxidant-nutraceuticals-and-herbal-products-an-overview-of-pre-clinical-and-clinical-studies
#5
Sajal Jain, Harpal S Buttar, Meena Chintameneni, Ginpreet Kaur
BACKGROUND: Inflammation-induced endothelial abnormalities, dietary habits, and tobacco smoking are considered to be the primary risk factors for causing atherosclerosis and cardiovascular diseases (CVDs), including coronary heart disease (CHD), cerebrovascular disorders, peripheral arterial disease, rheumatic heart disease, congenital heart defects, deep vein thrombosis and pulmonary embolism. Prevention of CVDs with anti-inflammatory and anti-oxidant agents has been a challenging task for decades...
August 15, 2018: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/30109826/physiological-consequences-of-coronary-arteriolar-dysfunction-and-its-influence-on-cardiovascular-disease
#6
Hassan Allaqaband, David D Gutterman, Andrew O Kadlec
To date, the major focus of diagnostic modalities and interventions to treat coronary artery disease has been the large epicardial vessels. Despite substantial data showing that microcirculatory dysfunction is a strong predictor of future adverse cardiovascular events, very little research has gone into developing techniques for in vivo diagnosis and therapeutic interventions to improve microcirculatory function. In this review, we will discuss the pathophysiology of coronary arteriolar dysfunction, define its prognostic implications, evaluate the diagnostic modalities available, and provide speculation on current and potential therapeutic opportunities...
September 1, 2018: Physiology
https://www.readbyqxmd.com/read/30109764/are-component-endpoints-equal-a-preference-study-into-the-practice-of-composite-endpoints-in-clinical-trials
#7
Melissa C W Vaanholt, Marlies M Kok, Clemens von Birgelen, Marieke G M Weernink, Janine A van Til
OBJECTIVES: To examine patients' perspectives regarding composite endpoints and the utility patients put on possible adverse outcomes of revascularization procedures. DESIGN: In the PRECORE study, a stated preference elicitation method Best-Worst Scaling (BWS) was used to determine patient preference for 8 component endpoints (CEs): need for redo percutaneous coronary intervention (PCI) within 1 year, minor stroke with symptoms <24 hours, minor myocardial infarction (MI) with symptoms <3 months, recurrent angina pectoris, need for redo coronary artery bypass grafting (CABG) within 1 year, major MI causing permanent disability, major stroke causing permanent disability and death within 24 hours...
August 14, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/30109454/the-association-of-right-ventricular-dysfunction-with-in-hospital-and-1-year-outcomes-in-anterior-myocardial-infarction
#8
Muhammed Keskin, Ahmet Okan Uzun, Mert İlker Hayıroğlu, Adnan Kaya, Tufan Çınar, Ömer Kozan
In anterior ST-segment elevation myocardial infarction (STEMI), attention paid mainly to the left ventricle. The predictive significance of right ventricular (RV) dysfunction in patients with anterior STEMI has been frequently neglected. In this study, we evaluated the prognostic effect of RV dysfunction on in-hospital and long-term outcomes in patients with first anterior STEMI. A total of 350 patients without known coronary artery disease with first anterior STEMI and treated with primary percutaneous coronary intervention were prospectively enrolled in this study...
August 14, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/30108660/effectiveness-and-safety-of-compound-chinese-medicine-plus-routine-western-medicine-in-in-stent-restenosis-a-meta-analysis-and-systematic-review
#9
REVIEW
Lu Liu, Jing Liu, Qun Gao, Yang Wu, Jinjin Lu, Jie Wan, Yan Li, Xiaoyun Cui, Kun Zhou, Wenhao Jia, Yanchao Huang, Wenbai Qu, Qian Lin
Objective: To examine the effects and safety of oral compound Chinese medicine (CCM) plus routine western medicine (RWM) in in-stent restenosis (ISR). Methods: Various electronic databases (CBM, CNKI, VIP, Wanfang, PubMed, EMBASE, and Cochrane Library) were searched until April 2017. The quality of the included studies was evaluated, and meta-analyses were performed using RevMan5.3 and STATA 12.0 software. Moreover, funnel plot and Egger's publication bias plots were analysed to identify publication bias and adverse reactions were reported...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/30108641/distal-accesses-in-the-hand-two-novel-techniques-for-percutaneous-coronary-angiography-and-intervention
#10
Farshad Roghani-Dehkordi, Omid Hashemifard, Masoumeh Sadeghi, Rohollah Mansouri, Mehdi Akbarzadeh, Asieh Dehghani, Mojtaba Akbari
BACKGROUND: Trans-radial and trans-ulnar accesses have been practiced and recommended as default and alternative techniques for coronary angiography and angioplasty in recent years. In this study, we present new innovative approaches using more distal access points, i.e. trans-snuff box and trans-palmar approaches. METHODS: We conducted dorsal hand access (trans-snuff box) for angiography and/or angioplasty on 235 patients, and trans-palmar access (superficial palmar branch of ulnar artery) on 175 patients in 3 hospitals in Isfahan City, Iran...
March 2018: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/30108190/feasibility-of-transradial-access-for-coronary-interventions-via-percutaneous-angioplasty-of-the-radial-artery-in-cases-of-functional-radial-occlusion
#11
Michael Schulte-Hermes, Oliver Klein-Wiele, Marc Vorpahl, Melchior Seyfarth
AIMS: Transradial access (TRA) has become a standard approach for cardiac catheterization. However, an obstacle to TRA is the risk of radial artery occlusion (RAO) after radial access in about 5%-10% of patients. We analyzed the safety and efficacy of getting vascular access after RAO by percutaneous transluminal angioplasty in cases of chronic radial occlusion. METHODS AND RESULTS: Chronic RAO was confirmed by Allen test and color Doppler in 8 patients. TRA was achieved by puncture in the distal tabatiere (anatomical snuffbox) using Seldinger's technique followed by insertion of a 5 Fr radial introducer sheath...
August 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/30107905/heart-rate-as-a-predictor-of-outcome-following-percutaneous-coronary-intervention
#12
Jessica O'Brien, Christopher M Reid, Nick Andrianopoulos, Andrew E Ajani, David J Clark, Henry Krum, Philippa Loane, Melanie Freeman, Martin Sebastian, Angela L Brennan, James Shaw, Anthony M Dart, Stephen J Duffy
Data from previous studies of patients with heart failure and coronary artery disease suggest that those with higher resting heart rates (HRs) have worse cardiovascular outcomes. We sought to evaluate whether HR immediately before percutaneous coronary intervention (PCI) is an independent predictor for 30-day outcome. We analyzed the outcome of 3,720 patients who had HR recorded before PCI from the Melbourne Interventional Group registry. HR and outcomes were analyzed by quintiles, and secondarily by dichotomizing into <70 or ≥70 beats/min...
July 4, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30107794/biodegradable-polymer-drug-eluting-stents-versus-second-generation-drug-eluting-stents-in-patients-with-and-without-diabetes-mellitus-a-single-center-study
#13
Xiao-Fang Tang, Yuan-Liang Ma, Ying Song, Jing-Jing Xu, Yi Yao, Chen He, Huan-Huan Wang, Ping Jiang, Lin Jiang, Ru Liu, Zhan Gao, Xue-Yan Zhao, Shu-Bin Qiao, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan
BACKGROUND: To improve outcomes in patients with diabetes mellitus (DM) undergoing percutaneous coronary intervention remain an unmet clinical need. The study aimed to evaluate the efficacy and safety of G2-DESs and BP-DESs in patients with and without DM in a single center in China. METHODS: A total of 7666 consecutive patients who exclusively had G2-DES or BP-DES implantation throughout 2013 in our center were studied. The primary efficacy endpoint was any target lesion revascularization (TLR), whereas the primary safety endpoint was a composite of death or myocardial infarction (MI) at 2-year follow-up...
August 14, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/30105763/st-segment-elevation-myocardial-infarction-possibly-caused-by-thromboembolism-from-left-atrial-appendage-thrombus-after-incomplete-surgical-ligation
#14
Ahmet Guner, Alev Kılıcgedik, Macit Kalçık, Mehmet Ozkan
Coronary embolism (CE) is the underlying cause of 3% of acute coronary syndromes but is frequently overlooked in the differential diagnoses of acute coronary syndromes. The CE may be direct (left sided from the native or prosthetic heart valve, the left atrium, left atrial appendage or pulmonary venous bed), paradoxical (from the venous circulation through a patent foramen ovale, atrial septal defect, ventricular septal defects, cyanotic congenital heart defects or pulmonary arteriovenous malformations), or iatrogenic (following cardiac interventions...
August 13, 2018: Echocardiography
https://www.readbyqxmd.com/read/30105467/determination-of-the-frequency-of-right-and-left-internal-mammary-artery-embolization-in-single-ventricle-patients-a-two-center-study
#15
Bassel Mohammad Nijres, Anas S Taqatqa, Lamya Mubayed, Gregory J Jutzy, Ra-Id Abdulla, Karim A Diab, Hoang H Nguyen, Brieann A Muller, Cyndi R Sosnowski, Joshua J Murphy, Joseph Vettukattil, Vishal R Kaley, Darcy N Marckini, Bennett P Samuel, Khaled Abdelhady, Sawsan Awad
Embolization of systemic to pulmonary artery collaterals to regulate pulmonary arterial flow or pressure of the cavopulmonary circulation in patients with single ventricle is a common practice. The relative incidence and impact of this practice on future interventions like coronary artery bypass grafting is poorly understood. This study aims to evaluate the frequency and implications of internal mammary artery (IMA) embolization in the single ventricle (SV) population. A retrospective chart review was performed of SV patients who underwent cardiac catheterization before and after Fontan procedure between February 2007 and 2017...
August 13, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/30104982/effects-of-hypoxia-and-bed-rest-on-markers-of-cardiometabolic-risk-compensatory-changes-in-circulating-trail-and-glutathione-redox-capacity
#16
Gianni Biolo, Filippo G Di Girolamo, Adam McDonnell, Nicola Fiotti, Filippo Mearelli, Roberta Situlin, Arianna Gonelli, Barbara Dapas, Mauro Giordano, Mitja Lainscak, Gabriele Grassi, Giorgio Zauli, Paola Secchiero, Igor Mekjavic
In chronic diseases, hypoxia and physical inactivity are associated with atherosclerosis progression. In contrast, a lower mortality from coronary artery disease and stroke is observed in healthy humans residing at high altitude in hypoxic environments. Eleven young, male volunteers completed the following 10-day campaigns in a randomized order: hypoxic ambulatory, hypoxic bed rest and normoxic bed rest. Before intervention, subjects were evaluated in normoxic ambulatory condition. Normobaric hypoxia was achieved in a hypoxic facility simulating 4000 m of altitude...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30104697/comparison-of-radial-artery-occlusion-following-transradial-access-for-percutaneous-coronary-intervention-using-sheath-based-versus-sheathless-technique
#17
Ala Mohsen, Musab Alqasrawi, Ghanshyam Palamaner Subash Shantha, Chris DeZorzi, Sidakpal Panaich
We compared the risk of radial artery occlusion (RAO) in patients undergoing coronary intervention with introducer sheath (SG) or without introducer sheath (SLG). 1251 consecutive patients, from 2 tertiary care center in Pennsylvania, USA, undergoing percutaneous coronary interventions (PCI) between 2008-2013 formed the study cohort (SLG: 161 patients, SG: 1090 patients). Radial artery patency was assessed using plethysmography. The association between sheath use and RAO was assessed using unadjusted, adjusted and propensity macthed logistic regression analyses...
August 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30104395/heartbeat-the-ongoing-controversy-of-intervention-for-chronic-total-coronary-occlusions
#18
Catherine M Otto
No abstract text is available yet for this article.
September 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30103677/assessment-of-barriers-and-facilitators-in-the-implementation-of-appropriate-use-criteria-for-elective-percutaneous-coronary-interventions-a-qualitative-study
#19
Anne Lambert-Kerzner, Charles Maynard, Marina McCreight, Amy Ladebue, Katherine M Williams, Kelty B Fehling, Steven M Bradley
BACKGROUND: The use of inappropriate elective Percutaneous Coronary Intervention (PCI) has decreased over time, but hospital-level variation in the use of inappropriate PCI persists. Understanding the barriers and facilitators to the implementation of Appropriate Use Criteria (AUC) guidelines may inform efforts to improve elective PCI appropriateness. METHODS: All hospitals performing PCI in Washington State were categorized by their use of inappropriate elective PCI in 2010 to 2013...
August 13, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/30103241/genotype-phenotype-association-and-impact-on-outcomes-following-guided-de-escalation-of-anti-platelet-treatment-in-acute-coronary-syndrome-patients-the-tropical-acs-genotyping-substudy
#20
Lisa Gross, Dietmar Trenk, Claudius Jacobshagen, Anne Krieg, Meinrad Gawaz, Steffen Massberg, Monika Baylacher, Daniel Aradi, Fabian Stimpfle, Julia Hromek, Anja Vogelgesang, Martin Hadamitzky, Dirk Sibbing, Tobias Geisler
BACKGROUND:  Phenotype-guided de-escalation (PGDE) of P2Y12 -inhibitor treatment with an early switch from prasugrel to clopidogrel was identified as an effective alternative treatment strategy in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). The Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes (TROPICAL-ACS) Genotyping Substudy aimed to investigate whether CYP2C19 genotypes correlate with on-treatment platelet reactivity (PR) in ACS patients treated with clopidogrel or prasugrel and thus might be useful for guidance of early de-escalation of anti-platelet treatment...
August 13, 2018: Thrombosis and Haemostasis
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