Cheng Yin, Andrias O O'Reilly, Shao-Nan Liu, Tian-Hua Du, Pei-Pan Gong, Cheng-Jia Zhang, Xue-Gao Wei, Jing Yang, Ming-Jiao Huang, Bu-Li Fu, Jin-Jin Liang, Hu Xue, Jin-Yu Hu, Yao Ji, Chao He, He Du, Chao Wang, Rong Zhang, Qi-Mei Tan, Han-Tang Lu, Wen Xie, Dong Chu, Xu-Guo Zhou, Ralf Nauen, Lian-You Gui, Chris Bass, Xin Yang, You-Jun Zhang
Neonicotinoid insecticides, which target insect nicotinic acetylcholine receptors (nAChRs), have been widely and intensively used to control the whitefly, Bemisia tabaci, a highly damaging, globally distributed, crop pest. This has inevitably led to the emergence of populations with resistance to neonicotinoids. However, to date, there have been no reports of target-site resistance involving mutation of B. tabaci nAChR genes. Here we characterize the nAChR subunit gene family of B. tabaci and identify dual mutations (A58T&R79E) in one of these genes (BTβ1) that confer resistance to multiple neonicotinoids...
February 2024: PLoS Genetics