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https://read.qxmd.com/read/37456755/identifying-subgroups-of-patients-with-type-2-diabetes-based-on-real-world-traditional-chinese-medicine-electronic-medical-records
#1
JOURNAL ARTICLE
Shuai Zhao, Hengfei Li, Xuan Jing, Xuebin Zhang, Ronghua Li, Yinghao Li, Chenguang Liu, Jie Chen, Guoxia Li, Wenfei Zheng, Qian Li, Xue Wang, Letian Wang, Yuanyuan Sun, Yunsheng Xu, Shihua Wang
Introduction: Type 2 diabetes (T2D) is a multifactorial complex chronic disease with a high prevalence worldwide, and Type 2 diabetes patients with different comorbidities often present multiple phenotypes in the clinic. Thus, there is a pressing need to improve understanding of the complexity of the clinical Type 2 diabetes population to help identify more accurate disease subtypes for personalized treatment. Methods: Here, utilizing the traditional Chinese medicine (TCM) clinical electronic medical records (EMRs) of 2137 Type 2 diabetes inpatients, we followed a heterogeneous medical record network (HEMnet) framework to construct heterogeneous medical record networks by integrating the clinical features from the electronic medical records, molecular interaction networks and domain knowledge...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/25881421/-effect-of-algorithms-for-calibration-set-selection-on-quantitatively-determining-asiaticoside-content-in-centella-total-glucosides-by-near-infrared-spectroscopy
#2
JOURNAL ARTICLE
Xue-yan Zhan, Na Zhao, Zhao-zhou Lin, Zhi-sheng Wu, Rui-juan Yuan, Yan-jiang Qiao
The appropriate algorithm for calibration set selection was one of the key technologies for a good NIR quantitative model. There are different algorithms for calibration set selection, such as Random Sampling (RS) algorithm, Conventional Selection (CS) algorithm, Kennard-Stone(KS) algorithm and Sample set Portioning based on joint x-y distance (SPXY) algorithm, et al. However, there lack systematic comparisons between two algorithms of the above algorithms. The NIR quantitative models to determine the asiaticoside content in Centella total glucosides were established in the present paper, of which 7 indexes were classified and selected, and the effects of CS algorithm, KS algorithm and SPXY algorithm for calibration set selection on the accuracy and robustness of NIR quantitative models were investigated...
December 2014: Guang Pu Xue Yu Guang Pu Fen Xi, Guang Pu
https://read.qxmd.com/read/23297551/herbal-compatibility-of-traditional-chinese-medical-formulas-for-acquired-immunodeficiency-syndrome
#3
JOURNAL ARTICLE
Meng Cui, Jinghua Li, Haiyan Li, Chunxin Song
OBJECTIVE: Because herbal compatibility is one of the most important reasons why Traditional Chinese Medcine (TCM) formulas are effective for acquired immunodeficiency syndrome (AIDS), our study aimed to determine the compatibility of herbs based on published AIDS clinical research in Chinese periodicals. To achieve this aim, we designed a new data-mining algorithm according to TCM data characteristics. METHODS: We found 25 clinical AIDS studies, all using Chinese herbs for treatment, in the Traditional Chinese Medicine Database System, and information on diagnosis and treatment was extracted...
September 2012: Journal of Traditional Chinese Medicine
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