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Microsurgery

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https://www.readbyqxmd.com/read/27923103/noninvasive-microsurgery-using-aptamer-functionalized-magnetic-microdisks-for-tumor-cell-eradication
#1
Tatiana N Zamay, Galina S Zamay, Irina V Belyanina, Sergey S Zamay, Valery V Denisenko, Olga S Kolovskaya, Tatiana I Ivanchenko, Valentina L Grigorieva, Irina V Garanzha, Dmitry V Veprintsev, Yury E Glazyrin, Alexandr V Shabanov, Viktor Y Prinz, Vladimir A Seleznev, Alexey E Sokolov, Vladimir S Prokopenko, Petr D Kim, Ana Gargaun, Maxim V Berezovski, Anna S Zamay
Magnetomechanical cell disruption using nano- and microsized structures is a promising biomedical technology used for noninvasive elimination of diseased cells. It applies alternating magnetic field (AMF) for ferromagnetic microdisks making them oscillate and causing cell membrane disruption with cell death followed by apoptosis. In this study, we functionalized the magnetic microdisks with cell-binding DNA aptamers and guided the microdisks to recognize cancerous cells in a mouse tumor in vivo. Only 10 min of the treatment with a 100 Hz AMF was enough to eliminate cancer cells from a malignant tumor...
December 6, 2016: Nucleic Acid Therapeutics
https://www.readbyqxmd.com/read/27920937/conversion-technique-from-neuroendoscopy-to-microsurgery-in-ventricular-tumors-technical-note
#2
Pedro Henrique da C F Pinto, Flavio Nigri, Gabriel N Gobbi, Egas M Caparelli-Daquer
BACKGROUND: Ventricular tumors represent a major neurosurgical challenge, making endoscopic approach an invaluable tool as it gained importance due to technological advances. Nevertheless, the method is not exempt of risk and limitations, sometimes requiring an open surgery. Thus, initial measurements must be adopted in order to simplify an eventual need for conversion to open craniotomy. METHODS: Here, we describe a series of 6 patients with ventricular tumors approached by neuroendoscopy where the conversion to microsurgery turned out to be necessary...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27919114/a-low-cost-high-definition-video-system-for-microsurgical-hindlimb-replantation-in-rats
#3
Rui Sergio, Monteiro de Barros, Marcus Vinicius Henriques Brito, Rafael Aquino Leal, Renan Kleber Costa Teixeira, Marcelo Ferreia Sabbá, Vitor Nagai Yamaki, Marcos Vinicius Vieira Lemos
Background The surgical microscope is still essential for microsurgery, but several alternatives that show promising results are currently under development, such as endoscopes and laparoscopes with video systems; however, as yet, these have only been used for arterial anastomoses. The aim of this study was to evaluate the use of a low-cost video-assisted magnification system in replantation of the hindlimbs of rats. Methods Thirty Wistar rats were randomly divided into two matched groups according to the magnification system used: the microscope group, with hindlimb replantation performed under a microscope with an image magnification of 40× and the video group, with the procedures performed under a video system composed of a high-definition camcorder, macrolenses, a 42-in television, and a digital HDMI cable...
December 5, 2016: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/27916723/surgical-treatment-of-metallic-foreign-body-embolization-in-the-middle-cerebral-artery-case-report-and-literature-review
#4
Chuan Chen, Bo Hou, Lun Luo, Ying Guo
Intracranial artery embolization cases caused by foreign bodies are extremely clinically rare. Twenty-four cases in total have been reported in the literature; among them, 20 cases were caused by firearms, and only four cases originated from non-firearm injuries in daily life. Here, we report a fifth case of foreign body embolization in the cerebral artery caused by non-firearm injuries. We used microsurgery and successfully removed the metal piece that embolized the middle cerebral artery of a 30-year-old male patient in our center...
December 1, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27916035/-microsurgical-management-and-outcomes-of-intramedullary-spinal-arteriovenous-malformations-a-report-of-14-cases
#5
L Zhang, W Q Jia, J Yang
Objective: To investigate the clinical features, microsurgical management and outcomes of intramedullary spinal arteriovenous malformations (AVM). Methods: A series of 14 patients (10 male, 4 female; mean age (39.1±17.2) years ranged from 16 to 72 years) with intramedullary spinal AVM who underwent microsurgical treatment from November 2008 to April 2015 in Department of Neurosurgery at Beijing Tiantan Hospital were retrospectively reviewed. The location of the AVM included cervical (n=6), thoracic (n=3), cervicothoracic (n=2), and conus medullaris (n=3)...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27913800/the-transvenous-pressure-cooker-technique-a-treatment-for-brain-arteriovenous-malformations
#6
Guang Zhang, Shiyi Zhu, Pei Wu, Shancai Xu, Huaizhang Shi
The treatment of brain arteriovenous malformations (AVMs) remains a significant challenge, especially hemorrhagic AVMs which are unsuitable for microsurgery or radiosurgery. We demonstrate an AVM located in the left basal ganglia area, supplied by slender arteries, and treated by the transvenous pressure cooker technique. Herein, we describe the procedure and outline the crucial points and indications for this technique.
December 2, 2016: Interventional Neuroradiology
https://www.readbyqxmd.com/read/27912820/modern-endodontic-microsurgery-concepts-a-clinical-update
#7
REVIEW
Spyros Floratos, Syngcuk Kim
Increased use of the surgical operating microscope in endodontic surgery has elucidated many shortcomings of previous techniques and along with microsurgical instruments and new more biologically acceptable root-end filling materials has started the new microsurgical era in surgical endodontics. Endodontic microsurgery is a minimally invasive technique that results in less postoperative pain and edema and faster wound healing. It offers a significantly higher success rate than traditional apical surgery technique...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27911236/patient-versus-physician-reported-facial-disability-in-vestibular-schwannoma-an-international-cross-sectional-study
#8
Øystein Vesterli Tveiten, Matthew L Carlson, Frederik Goplen, Erling Myrseth, Colin L W Driscoll, Rupavathana Mahesparan, Michael J Link, Morten Lund-Johansen
OBJECTIVE Patient-reported outcomes are increasingly used in studies of vestibular schwannoma (VS); however, few studies have examined self-evaluated facial nerve function and its relation to physician-reported outcomes. The primary objective of this study was to compare patient self-evaluations of facial disability with physician-evaluated facial nerve status and with self-evaluations of a healthy control group. The second objective was to provide insight into the controversial subject of the optimal initial management of small- and medium-sized VSs; consequently, the authors compared patient-reported facial nerve disability following treatment via observation (OBS), Gamma Knife surgery (GKS), or microsurgery (MS)...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27903180/results-of-volume-staged-fractionated-gamma-knife-radiosurgery-for-large-complex-arteriovenous-malformations-obliteration-rates-and-clinical-outcomes-of-an-evolving-treatment-paradigm
#9
Alberto Franzin, Pietro Panni, Giorgio Spatola, Antonella Del Vecchio, Alberto L Gallotti, Carmen R Gigliotti, Andrea Cavalli, Carmine A Donofrio, Pietro Mortini
OBJECTIVE There are few reported series regarding volume-staged Gamma Knife radiosurgery (GKRS) for the treatment of large, complex, cerebral arteriovenous malformations (AVMs). The object of this study was to report the results of using volume-staged Gamma Knife radiosurgery for patients affected by large and complex AVMs. METHODS Data from 20 patients with large AVMs were prospectively included in the authors' AVM database between 2004 and 2012. A staging strategy was used when treating lesion volumes larger than 10 cm(3)...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27903125/outcomes-in-transcranial-microsurgery-versus-extended-endoscopic-endonasal-approach-for-primary-resection-of-adult-craniopharyngiomas
#10
Todd J Wannemuehler, Kolin E Rubel, Benjamin K Hendricks, Jonathan Y Ting, Troy D Payner, Mitesh V Shah, Aaron A Cohen-Gadol
OBJECTIVE Craniopharyngiomas have historically been resected via transcranial microsurgery (TCM). In the last 2 decades, the extended endoscopic endonasal (transtuberculum) approach to these tumors has become more widely accepted, yet there remains controversy over which approach leads to better outcomes. The purpose of this study is to determine whether differences in outcomes were identified between TCM and extended endoscopic endonasal approaches (EEEAs) in adult patients undergoing primary resection of suprasellar craniopharyngiomas at a single institution...
December 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27900036/management-of-pediatric-head-and-neck-rhabdomyosarcoma-a-case-series-of-36-patients
#11
Joanna Radzikowska, Wojciech Kukwa, Andrzej Kukwa, Anna M Czarnecka, Maciej Kawecki, Fei Lian, Cezary Szczylik, Antoni Krzeski
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric population. In 35% of cases, RMS develops in the head and neck (H&N) region, and only combined therapy is recognized as a curative treatment. However, recent advances in skull base and reconstructive surgery, along with microsurgery and endoscopic surgery, have strengthened the role of surgery as an important part of RMS treatment. In the present study, 36 pediatric RMS cases (24 males and 12 females) were analyzed after surgical treatment...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27896195/microsurgical-training-using-reusable-human-vessels-from-discarded-tissues-in-lymph-node-dissection
#12
Naohiro Ishii, Tomoki Kiuchi, Tomito Oji, Kazuo Kishi
The use of human vessels at the beginning of microsurgery training is highly recommended. But vessels with the appropriate length for training are not often obtained. Whether these vessels may be reused for training has not been reported. Accordingly, we harvested vessels from discarded tissues in lymph node dissection and demonstrated that vascular anastomosis training using the same human vessels several times is possible by placing the vessels in a freezer and defrosting them with hot water. Vascular walls can be stored for microsurgical training until about 4 years after harvest, as shown in the gross appearance and histologic findings of our preserved vessels...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27896018/development-and-preliminary-results-of-bimanual-smart-micro-surgical-system-using-a-ball-lens-coupled-oct-distance-sensor
#13
Dongwoo Koo, Hyun-Cheol Park, Peter L Gehlbach, Cheol Song
Bimanual surgery enhances surgical effectiveness and is required to successfully accomplish complex microsurgical tasks. The essential advantage is the ability to simultaneously grasp tissue with one hand to provide counter traction or exposure, while dissecting with the other. Towards enhancing the precision and safety of bimanual microsurgery we present a bimanual SMART micro-surgical system for a preliminary ex-vivo study. To the best of our knowledge, this is the first demonstration of a handheld bimanual microsurgical system...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27896003/kagome-fiber-based-ultrafast-laser-microsurgery-probe-delivering-micro-joule-pulse-energies
#14
Kaushik Subramanian, Ilan Gabay, Onur Ferhanoğlu, Adam Shadfan, Michal Pawlowski, Ye Wang, Tomasz Tkaczyk, Adela Ben-Yakar
We present the development of a 5 mm, piezo-actuated, ultrafast laser scalpel for fast tissue microsurgery. Delivery of micro-Joules level energies to the tissue was made possible by a large, 31 μm, air-cored inhibited-coupling Kagome fiber. We overcome the fiber's low NA by using lenses made of high refractive index ZnS, which produced an optimal focusing condition with 0.23 NA objective. The optical design achieved a focused laser spot size of 4.5 μm diameter covering a 75 × 75 μm(2) scan area in a miniaturized setting...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27894583/pre-expanded-supraclavicular-artery-perforator-flap
#15
REVIEW
Norbert Pallua, Bong-Sung Kim
The supraclavicular artery perforator (SAP) flap is a versatile flap for the reconstruction of head and neck defects. Recently, the authors have modified the SAP flap by using an anterior branch of the transverse cervical artery. The anterior SAP flap allows the harvest of a tissue island in the deltopectoral fossa, which is even thinner, is more pliable, and shows a superior color match to the face and neck compared with the original SAP flap. Pre-expansion increases flap size considerably, enabling the coverage of extended defects without the need of microsurgery...
January 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/27893542/safety-and-suitability-of-finger-replantations-as-a-residency-training-procedure-a-retrospective-cohort-study-with-analysis-of-the-initial-postoperative-outcomes
#16
Dimitra Kotsougiani, Felicitas Ringwald, Caroline A Hundepool, Florian Neubrech, Thomas Kremer, Berthold Bickert, Ulrich Kneser, Christoph Hirche
Finger replantations demand technical excellence in microsurgery and hand trauma care. The objective of this study was to determine whether finger replantations constitute an appropriate and safe procedure for residency training. Additionally, the prognostic risk factors for the need to take a replanted finger back to the operation room and replant failure were analyzed.All patients who underwent finger replantation after complete amputation between 2007 and 2015 were included in a retrospective comparative study...
November 23, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27892668/transanal-endoscopic-microsurgery-in-the-treatment-of-large-rectal-adenomas
#17
Mario Guerrieri, Monica Ortenzi, Giovanni Lezoche, Stefano Mancini, Roberto Ghiselli
BACKGROUND: Transanal endoscopic microsurgery (TEM) is a minimally invasive technique allowing to excise large rectal adenomas by local approach. This study shows the feasibility and results of a long term experience of TEM applied in this field. METHODS: A retrospective investigation was performed in patients affected by rectal adenomas (5-11 cm in diameter) who had undergone transanal endoscopic microsurgery from 1992 to 2015. A series of 207 patients met the inclusion criteria and were analyzed for characteristics, intraoperative and postoperative results and long-term follow-up...
December 2016: Minerva Chirurgica
https://www.readbyqxmd.com/read/27890764/spontaneous-spinal-epidural-hematoma-a-study-of-55-cases-focused-on-the-etiology-and-treatment-strategy
#18
Jiaxing Yu, Jiang Liu, Chuan He, Liyong Sun, Sishi Xiang, Yongjie Ma, Lisong Bian, Tao Hong, Jian Ren, Pengyu Tao, Jingwei Li, Guilin Li, Feng Ling, Hongqi Zhang
BACKGROUND: Spontaneous spinal epidural hematoma (SSEH) is a rare neurological emergency of the spinal cord. Its etiology and treatment strategy remain controversial. This study aimed to evaluate a significant cause of SSEH and to discuss the treatment strategy according to the clinical outcomes of patients in two institutions. METHODS: Fifty-five cases of SSEH treated at our institutions between February 2002 and February 2016 were retrospectively analyzed. RESULT: The mean age of the first SSEH onset was 31...
November 24, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27888300/analysis-of-local-recurrences-after-transanal-endoscopic-microsurgery-for-low-risk-rectal-carcinoma
#19
Theodor Junginger, Ursula Goenner, Mirjam Hitzler, Tong T Trinh, Achim Heintz, Wilfried Roth, Maria Blettner, Daniel Wollschlaeger
AIM: Rates of local recurrence (LR) after transanal endoscopic microsurgery (TEM) for rectal carcinoma vary; the reasons remain unclear. We analyzed LR after TEM for low-risk pT1 (G1/2/X, L0/X) rectal carcinoma to investigate the influence of completeness of resection and occult lymph node metastasis on risk of LR. METHOD: LR location and stage, completeness of resection of primary carcinoma (minimal distance between tumor and resection line ≤1 mm vs >1 mm), and incidence of involved lymph nodes in resected LR specimens were collected, and tumor characteristics of LR were compared with primary carcinoma...
November 25, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27878799/microsurgery-robots-addressing-the-needs-of-high-precision-surgical-interventions
#20
Leonardo S Mattos, Darwin G Caldwell, Giorgio Peretti, Francesco Mora, Luca Guastini, Roberto Cingolani
Robotics has a significant potential to enhance the overall capacity and efficiency of healthcare systems. Robots can help surgeons perform better quality operations, leading to reductions in the hospitalisation time of patients and in the impact of surgery on their postoperative quality of life. In particular, robotics can have a significant impact on microsurgery, which presents stringent requirements for superhuman precision and control of the surgical tools. Microsurgery is, in fact, expected to gain importance in a growing range of surgical specialties as novel technologies progressively enable the detection, diagnosis and treatment of diseases at earlier stages...
2016: Swiss Medical Weekly
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