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Human milk fortified

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https://www.readbyqxmd.com/read/30339378/highly-sensitive-detection-of-bovine-%C3%AE-lactoglobulin-with-wide-linear-dynamic-range-based-on-platinum-nanoparticles-probe
#1
Shengfa He, Xin Li, Yong Wu, Shandong Wu, Zhihua Wu, Anshu Yang, Ping Tong, Juanli Yuan, Jinyan Gao, Hongbing Chen
Cows' milk allergy is one of the most frequent and severe IgE-induce food allergies for children, demanding sensitive analytical methods, and β-lactoglobulin (BLG) can be as an important biomarker for detection of milk protein. In this study, a highly sensitive sandwich enzyme-linked immunosorbent assay (sELISA) based on a specific polyclonal antibody against human IgE linear epitopes of BLG and an anti-BLG polyclonal antibody-platinum nanoparticles probe was described for detection of BLG. This sELISA exhibited an ultra-wide linear range of 0...
October 19, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/30325750/nicu-discharge-feeding-bundle-improves-accuracy-of-postdischarge-feeding-preparation-and-potentially-prevents-readmission
#2
Kimberly Vollrath, Adam Rosenberg, Lisbeth Gabrielski, Jane Deacon, Susan Marshall, Andrew Rihn, Theresa Grover
BACKGROUND: Hospitalized infants often need fortified human milk and formulas for growth in the neonatal intensive care unit and postdischarge. Parents must learn how to properly mix infant feedings.At the initial Children's Hospital Colorado follow-up visit, baseline data revealed a 50% rate of mixing inaccuracy of discharge feeding recipes and identified the readmission of 2 infants with life-threatening hypernatremia. A gap in discharge teaching was identified. A quality improvement project was implemented at 2 affiliated neonatal intensive care units...
October 15, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/30320665/a-novel-donkey-milk-derived-human-milk-fortifier-in-feeding-preterm-infants-a-randomized-controlled-trial
#3
Enrico Bertino, Laura Cavallarin, Francesco Cresi, Paola Tonetto, Chiara Peila, Giulia Ansaldi, Melissa Raia, Alessia Varalda, Marzia Giribaldi, Amedeo Conti, Sara Antoniazzi, Guido E Moro, Elena Spada, Silvano Milani, Alessandra Coscia
OBJECTIVES: The purpose of the present randomized controlled clinical trial was to compare the use of donkey milk-derived fortifier with commercial bovine milk-derived fortifier in very preterm or very low-birthweight newborns, in terms of feeding tolerance. METHODS: This trial included 156 newborns born at <32 weeks of gestational age and/or with a birthweight ≤1500 g. Newborns were randomized 1:1 to receive enteral feeding with either a bovine milk-based fortifier (BF-arm), or a new, donkey milk-derived fortifier (DF-arm) for 21 days...
October 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/30320413/tolerance-of-hydrolyzed-liquid-protein-fortified-human-milk-and-effect-on-growth-in-premature-infants
#4
Fauzia Shakeel, Melanie Newkirk, Taymeyah Altoubah, Denise Martinez, Ernest K Amankwah
BACKGROUND: We evaluated tolerance of hydrolyzed liquid protein (LP) supplement added to fortified human milk (HM) to optimize protein intake in preterm infants. METHODS: A prospective observational study of 31 subjects compared with 31 historic controls, receiving mothers own milk (MOM) and/or donor milk (DM) to assess LP tolerance, growth, and risk for morbidities was conducted. Milk was analyzed for nutrient content. Feeding intolerance, defined as cessation of feedings for ≥48 hours, abdominal distension and/or residuals, necrotizing enterocolitis (NEC), and metabolic acidosis were used to assess safety, while weight and head circumference (HC) were used to evaluate growth...
October 15, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/30287775/evaluation-of-a-concentrated-preterm-formula-as-a-liquid-human-milk-fortifier-in-preterm-babies-at-increased-risk-of-feed-intolerance
#5
Anish Pillai, Susan Albersheim, Julie Matheson, Vikki Lalari, Sylvia Wei, Sheila M Innis, Rajavel Elango
There are concerns around safety and tolerance of powder human milk fortifiers to optimize nutrition in preterm infants. The purpose of this study was to evaluate the tolerance and safety of a concentrated preterm formula (CPF) as a liquid human milk fortifier (HMF) for premature infants at increased risk of feeding intolerance. We prospectively enrolled preterm infants over an 18-month period, for whom a clinical decision had been made to add CPF to human milk due to concerns regarding tolerance of powder HMF...
October 4, 2018: Nutrients
https://www.readbyqxmd.com/read/30252854/human-milk-enriched-with-human-milk-lyophilisate-for-feeding-very-low-birth-weight-preterm-infants-a-preclinical-experimental-study-focusing-on-fatty-acid-profile
#6
Vanessa S Bomfim, Alceu A Jordão, Larissa G Alves, Francisco E Martinez, José Simon Camelo
BACKGROUND: Human milk, with essential nutrients and long chain polyunsaturated fatty acids (LC-PUFAs) such as the omega 3 and 6 fatty acids is important for development of the central nervous system and the retina in very low birth weight infants (<1,500 g). However, breast milk may not be sufficient to meet these needs. The possibility of supplementing breast milk with a lyophilisate of human milk was explored in this study. The objectives of this study were to determine the total lipid content and the lipid profile of the Human Milk on Baseline (HMB) and that of the Concentrates with the Human Milk + lyophilisate (with lyophilisate of milk in the immediate period (HMCI), at 3 months (HMC3m), and at 6 months (HMC6m) of storage)...
2018: PloS One
https://www.readbyqxmd.com/read/30241780/osmolality-of-a-fortified-human-preterm-milk-the-effect-of-fortifier-dosage-gestational-age-lactation-stage-and-hospital-practices
#7
A Sauret, M-C Andro-Garçon, J Chauvel, A Ligneul, P Dupas, C Fressange-Mazda, P Le Ruyet, A Dabadie
OBJECTIVE: The purpose of this study was to evaluate the dose-dependent effect of human milk fortifier (HMF) on the osmolality of various preterm human milks (PHMs) at different gestational and lactation stages, and with different storage and treatment conditions that are routinely used in neonatal intensive care units (NICUs). STUDY DESIGN: Twenty-four mothers who had given birth to their baby before 28 or between 29 and 31 weeks of pregnancy participated in the study after 1-2 weeks or 3-4 weeks breastfeeding after delivery...
October 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/30237896/the-fortification-method-relying-on-assumed-human-milk-composition-overestimates-the-actual-energy-and-macronutrient-intakes-in-very-preterm-infants
#8
Israel Macedo, Luis Pereira-da-Silva, Manuela Cardoso
Background: To achieve recommended nutrient intakes in preterm infants, the target fortification method of human milk (HM) was proposed as an alternative to standard fortification method. We aimed to compare assumed energy and macronutrient intakes based on standard fortified HM with actual intakes relying on measured composition of human milk (HM), in a cohort of HM-fed very preterm infants. Methods: This study is a secondary retrospective analysis, in which assumed energy and macronutrient contents of daily pools of own mother's milk (OMM) from 33 mothers and donated HM (DHM) delivered to infants were compared with the measured values using a mid-infrared HM analyzer...
2018: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/30234121/best-practices-for-handling-and-administration-of-expressed-human-milk-and-donor-human-milk-for-hospitalized-preterm-infants
#9
REVIEW
Caroline Steele
The importance of human milk for the preterm infant is well established (1-3). However, the feeding of human milk to preterm infants is typically much more complicated than the mere act of breastfeeding (3, 4). The limited oral feeding skills of many preterm infants often results in human milk being administered via an enteral feeding tube (4). In addition, fortification is commonly required to promote optimal growth and development-particularly in the smallest of preterm infants (2, 4, 5). Consequently, a mother's own milk must be pumped, labeled, transported to the hospital, stored, tracked for appropriate expiration dates and times, thawed (if previously frozen), fortified, and administered to the infant with care taken at each step of the process to avoid microbial contamination, misadministration (the wrong milk for the wrong patient), fortification errors, and waste (1-5)...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/30215639/efficient-synthesis-of-riboflavin-imprinted-magnetic-nanoparticles-by-boronate-affinity-based-surface-imprinting-for-the-selective-recognition-of-riboflavin
#10
Daojin Li, Zijun Bie, Fangfang Wang, Enhui Guo
Riboflavin (vitamin B2), a cis-diol-containing compound, is an essential vitamin for maintaining human health mainly in energy metabolism and is a critical component of enzyme cofactors and flavoproteins. Thus, the determination of riboflavin in food products is essential in riboflavin-fortified foods. However, analysis of riboflavin at natural levels in foods or biological samples is difficult because of its very low concentration level and the presence of undesirable matrix effects which could interfere with the measuring system...
September 14, 2018: Analyst
https://www.readbyqxmd.com/read/30195561/improved-outcomes-in-preterm-infants-fed-a-nonacidified-liquid-human-milk-fortifier-a-prospective-randomized-clinical-trial
#11
Richard J Schanler, Sharon L Groh-Wargo, Bridget Barrett-Reis, Robert D White, Kaashif A Ahmad, Jeffery Oliver, Geraldine Baggs, Larry Williams, David Adamkin
OBJECTIVE: To compare growth, feeding tolerance, and clinical and biochemical evaluations in human milk-fed preterm infants randomized to receive either an acidified or a nonacidified liquid human milk fortifier. STUDY DESIGN: This prospective, controlled, parallel, multicenter growth and tolerance study included 164 preterm infants (≤32 weeks of gestation, birth weight 700-1500 g) who were randomized to acidified or nonacidified liquid human milk fortifier from study day 1, the first day of fortification, through study day 29 or until hospital discharge...
September 5, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/30194887/improved-lung-function-at-age-6-in-children-born-very-preterm-and-fed-extra-protein-post-discharge
#12
Line Hedegaard Toftlund, Lone Agertoft, Susanne Halken, Gitte Zachariassen
BACKGROUND: In very preterm-born children alveolar maturation is challenged and lung function is often compromised during childhood. So far, very few studies have focused on type of early nutrition and lung function in children born preterm. METHODS: This study is a six years follow-up of 281 very preterm-born infants (VPI) with a gestational age (GA) < 32+0 weeks. Infants breastfed at discharge from hospital were randomized to unfortified (UHM) or fortified (FHM) mother's (human) milk, whereas those not breastfed received a preterm formula (PF)...
September 8, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/30149743/late-onset-hyponatremia-in-preterm-newborns-is-the-sodium-content-of-human-milk-fortifier-insufficient
#13
İsmail Kursad Gokçe, Serife Suna Oguz
INTRODUCTION: In this study, we aimed to define the incidence and time to detection of late onset hyponatremia (LOH) as well as factors affecting its development in preterm newborns. We also aimed to determine the daily sodium requirement of these patients. METHODS: We studied a total of 145 very low birth weight infants with a full or nearly full enteral diet and followed them up until discharge. We recorded demographic and clinic characteristics. We measured serum sodium (SNa) levels at least once a week after the second week...
September 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30148655/effects-of-refrigerated-and-frozen-storage-on-holder-pasteurized-donor-human-milk-a-systematic-review
#14
Hannah R Schlotterer, Maryanne T Perrin
BACKGROUND: Pasteurized donor human milk (PDHM) is the recommended feeding alternative for preterm infants when mother's own milk is not available. Use of PDHM in United States neonatal hospitals is increasing, although guidelines for the refrigerated and frozen storage are limited. OBJECTIVE: We aimed to review the current evidence for the storage of Holder PDHM (HPDHM) under refrigerated and frozen storage conditions. METHODS: A systematic review of the literature was conducted for studies published between 1985 and May 2018...
September 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/30100515/antioxidant-and-antigenotoxic-effect-of-dairy-products-supplemented-with-red-ginseng-extract
#15
Hanyeong Park, Minhee Lee, Kee-Tae Kim, Eunju Park, Hyun-Dong Paik
The purpose of this study was to evaluate the antioxidant and antigenotoxic effect of dairy products milk (M) and yogurt (Y) after the addition of 2% red ginseng extract to milk (RM) and to yogurt (RY). Total phenolic content, total flavonoid content, 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, oxygen radical absorbance capacity, and total radical trapping antioxidant potential were determined in the samples. Furthermore, antigenotoxic effect of samples was measured, using comet assay in human leukocytes...
August 9, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/30022761/-effects-of-different-feeding-patterns-on-the-growth-and-development-of-infants-with-very-extremely-low-birth-weight
#16
Qian-Qian Li, Qian Liu, Jun-Mei Yan, Xian Wang
OBJECTIVE: To investigate the growth and development of very low birth weight (VLBW)/extremely low birth weight (ELBW) preterm infants within the corrected age of 6 months and the effect of different feeding patterns on growth and development. METHODS: A total of 109 VLBW/ELBW preterm infants who were discharged from January 2016 to April 2017 and who had completed regular follow-up were enrolled, and their growth and development within the corrected age of 6 months were monitored...
July 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/30011395/catch-up-growth-rapid-weight-growth-and-continuous-growth-from-birth-to-6-years-of-age-in-very-preterm-born-children
#17
Line Hedegaard Toftlund, Susanne Halken, Lone Agertoft, Gitte Zachariassen
BACKGROUND: Breastfeeding promotes healthy growth in very-preterm-born infants (VPI), but extra nutritional supply is needed to ensure catch-up growth and brain development. OBJECTIVES: To investigate how different types of post-discharge nutrition affect growth until 6 years of age in children born VPI. METHODS: This was a 6-year follow-up study of 281 VPI. Median gestational age (GA) was 30 + 0 weeks (range 24-32 weeks). When breastfed at discharge, they were randomized to unfortified human milk (UHM) or fortified human milk (FHM)...
July 16, 2018: Neonatology
https://www.readbyqxmd.com/read/29992630/human-milk-fortification-with-bovine-colostrum-is-superior-to-formula-based-fortifiers-to-prevent-gut-dysfunction-necrotizing-enterocolitis-and-systemic-infection-in-preterm-pigs
#18
Jing Sun, Yanqi Li, Xiaoyu Pan, Duc Ninh Nguyen, Anders Brunse, Anders M Bojesen, Silvia Rudloff, Martin S Mortensen, Douglas G Burrin, Per T Sangild
BACKGROUND: Fortification of donor human milk (DHM) is required for optimal growth of very preterm infants, but there are concerns of more gut dysfunction and necrotizing enterocolitis (NEC) when using formula-based fortifiers (FFs), especially soon after birth. Intact bovine colostrum (BC) is rich in nutrients and bioactive factors, and protects against NEC in preterm pigs. We hypothesized that fortification of DHM with BC is superior to FFs to prevent gut dysfunction and infections when provided shortly after preterm birth...
July 10, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29978378/pharmacokinetics-of-vitamin-e-%C3%AE-oryzanol-and-ferulic-acid-in-healthy-humans-after-the-ingestion-of-a-rice-bran-enriched-porridge-prepared-with-water-or-with-milk
#19
Laura A Calvo-Castro, Nadine Sus, Christina Schiborr, Anja Bosy-Westphal, Maria Luisa Duran, Doris Fesenmeyer, Gerhard Fesenmeyer, Jan Frank
PURPOSE: In this study, we investigated the absorption and excretion kinetics of antioxidant dietary phytochemicals (vitamin E, γ-oryzanol, and ferulic acid) in healthy humans after the ingestion of an oatmeal porridge supplemented with rice bran extract (RBE) prepared with water or with whole milk, and we compared it with the intake of an equivalent dose of the rice bran content, in the form of RBE oil. METHODS: Twelve healthy volunteers (6 men and 6 women) orally ingested RBE oil (2 g) or RBE-enriched porridge (35 g, including 2-g RBE) with water or with milk, in a three-armed, crossover trial...
July 5, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29971449/-the-value-of-human-milk-for-preterm-infants-overview-and-practical-aspects
#20
REVIEW
Corinna Gebauer, Daniel Klotz, Skadi Springer
Over the last decades the immense benefit of human milk on the nutrition of preterm infants has become increasingly evident. Research has confirmed that human milk has significant advantages for the preterm infant in terms of host defense, gastrointestinal development and maturation, neurological development, reduction of necrotizing enterocolitis, retinopathy of prematurity and chronic lung disease as well as mental and physical benefits for the mother. Computing these factors into a health-cost-benefit equation, positive economic consequences for a national public health system were demonstrated...
August 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
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