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Emergency Blood transfusion

Shokei Matsumoto, Kyoungwon Jung, Alan Smith, Motoyasu Yamazaki, Mitsuhide Kitano, Raul Coimbra
Background: The National Trauma Data Bank (NTDB) has served as a global benchmark for trauma care quality and outcomes. Herein, we compared patient characteristics, trauma management, and outcomes between Japanese emergency and critical care centers and US level 1 trauma centers using the Japanese Trauma Data Bank (JTDB) and NTDB. Methods: A retrospective cohort matching (1:1) study was performed. Patients treated in 2013 with an Injury Severity Score ≥9 were included...
2018: Trauma surgery & acute care open
Sofia Araújo Xavier, Firmino João Machado, Joana Teixeira Magalhães, José Berkeley Cotter
AIM: Acute lower gastrointestinal bleeding (ALGIB) is a commongastroenterological emergency. Despite this outcomes are difficult to predict Onlyy STRATE and BLEED scores are readily available. The aim of this study was to identify risk factors for severe ALGIB and access the validity of available scores. METHODS: Emergency consecutive admissions for ALGIB in the last 7 years were retrospectively reviewed. Severe ALGIB was defined as transfusion of ≥2 units of blood and/or hematocrit decrease of ≥20% within the first 24h and/or recurrent bleeding after 24h of stability...
December 7, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Anders Schack, Jakob Ohm Oreskov, Sarah Ekeloef, Thorsten Brodersen, Sisse Rye Ostrowski, Ismail Gögenur, Jakob Burcharth
BACKGROUND: ABO dependent variation in von Willebrand factor (vWF) and factor VIII have an impact on hemostasis. Several contradictory studies have investigated the influence of ABO blood type in surgical hemorrhage. Emergency surgery is associated with an increased risk of perioperative hemorrhage leading to inferior clinical outcomes. The aim of this study was to investigate if patients with blood type O received more transfusions with blood components compared with non-O patients after major emergency abdominal surgery...
December 10, 2018: Transfusion
Marco Raber, Noor N P Buchholz, Augusto Vercesi, Nashaat A Hendawi, Vincenzo Inneo, Giuseppe Di Paola, Lorenzo Tessa, Ismail M Hassan
Objectives: To report our experience with the emerging technique of thulium laser enucleation of the prostate (ThuLEP) for the treatment for prostate hyperplasia. Patients and methods: Our inclusion criteria were an International Prostate Symptom Score (IPSS) of >15 and a quality-of-life (QoL) score of >3 in patients with confirmed bladder outflow obstruction, no longer responsive to medical therapy, with a significant post-void residual urine volume (PVR; >100 mL), with or without recurrent urinary tract infection and/or acute urinary retention...
December 2018: Arab Journal of Urology
F I Ibragimov
AIM: To decrease disability and mortality in patients with severe combined pelvic and abdominal trauma via applications of new progressive treatment tactics. MATERIAL AND METHODS: Retrospective and prospective analysis included 1033 patients with severe combined traumas (SCT) who were treated at the Clinical Hospital #3 in 2009-2015. Patients were divided into 2 groups - control (2009-2010) and main (2011-2015) group. Treatment in control group was similar to conventional approaches...
2018: Khirurgiia
Joanna E Oakeshott, Joanne E Griggs, Gary M Wareham, Richard M Lyon
BACKGROUND: Early transfusion of patients with major traumatic haemorrhage may improve survival. This study aims to establish the feasibility of freeze-dried plasma transfusion in a Helicopter Emergency Medical Service in the UK. PATIENTS AND METHODS: A retrospective observational study of major trauma patients attended by Kent, Surrey and Sussex Helicopter Emergency Medical Service and transfused freeze-dried plasma since it was introduced in April 2014. RESULTS: Of the 1873 patients attended over a 12-month period before its introduction, 79 patients received packed red blood cells (4...
December 7, 2018: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
Mohammad Hamidi, Muhammad Zeeshan, Narong Kulvatunyou, Eseoghene Adun, Terence O'Keeffe, El Rasheid Zakaria, Lynn Gries, Bellal Joseph
BACKGROUND: Exsanguinating trauma patients often require massive blood transfusion (defined as transfusion of 10 or more pRBC units within first 24 h). The aim of our study is to assess the outcomes of trauma patients receiving massive transfusion at different levels of trauma centers. METHODS: Two-y (2013-2014) retrospective analysis of the American College of Surgeons Trauma Quality Improvement Program. We included all adult trauma patients who received massive transfusion (MT) of blood...
February 2019: Journal of Surgical Research
Jeffrey Yates, Iris Perelman, Simonne Khair, Joshua Taylor, Jacinthe Lampron, Alan Tinmouth, Elianna Saidenberg
BACKGROUND: Tranexamic acid (TXA) is an inexpensive therapy effective at minimizing perioperative blood loss and transfusion. However, it remains underutilized due to safety concerns. To date, no evidence-based guidelines exist identifying which patients should not receive TXA therapy. This study determined patient groups for whom safety information regarding TXA is lacking due to common exclusion from perioperative TXA trials. STUDY DESIGN AND METHODS: A systematic review searching the databases Medline, EMBASE, CENTRAL, and Clinicaltrials...
December 5, 2018: Transfusion
C Margarido, J Ferns, V Chin, T Ribeiro, B Nascimento, J Barrett, E Herer, S Halpern, L Andrews, G Ballatyne, M Chapmam, J Gomes, J Callum
BACKGROUND: A structured approach to hemorrhagic emergencies in obstetrics has gained popularity with the implementation of massive hemorrhage protocols. The trauma literature suggests that routine quality reviews should be in place to improve patient outcomes. The aim of this study was to develop quality indicators and assess compliance by the clinical team. METHODS: A multidisciplinary team set the institutional quality indicators for the massive hemorrhage protocol review...
November 3, 2018: International Journal of Obstetric Anesthesia
Francesca Punzo, Chiara Tortora, Maura Argenziano, Maddalena Casale, Silverio Perrotta, Francesca Rossi
Chronic blood transfusions are responsible to cause iron overload, which leads to several complications to end organs and osteoporosis. Iron chelation is needed to remove iron excess and to contain bone-mass loss. Deferasirox is the most recent oral iron chelator that prevents transfusion related iron overload complications. Recently Eltrombopag (ELT) iron chelating properties are emerging. ELT is an agonist at Thrombopoietin receptor, used in treatment of thrombocytopenia. We tested ELT and Deferasirox in iron overloaded osteoclasts from thalassemic patients and donors measuring intracellular iron, TRAP expression and osteoclast activity...
2018: PloS One
Sabrina Nolan, Kristian B Filion, Renee Atallah, Emmanuel Moss, Pauline Reynier, Mark J Eisenberg
BACKGROUND: Hybrid coronary revascularization (HCR) has emerged as a potential alternative to complete coronary artery bypass graft (CABG) surgery. However, the efficacy and safety of HCR vs CABG remain unclear. We therefore conducted a systematic review and meta-analysis to compare these interventions. METHODS: We systematically searched PubMed, MEDLINE (via Ovid), EMBASE (via Ovid), Cochrane Library of Clinical Trials, and the Web of Science for studies comparing HCR to CABG in patients with multivessel coronary artery disease...
December 2018: Journal of Invasive Cardiology
Labrini V Athanasiou, Constantina N Tsokana, Dimitra Pardali, Katerina Adamama Moraitou
Histograms, which are an integral part of the automated complete blood count, are now available through most of the automatic hematology analyzers used in veterinary clinical practice. Data concerning the size and number of blood cells are graphically presented in histograms, and their variations are also illustrated. Important information that is not apparent from numerical results are sometimes provided by histograms. Histograms are also referred to as frequency distribution curves and are essentially graphs resulting from the placement of the sizes of cells on the x-axis and the number of cells on the y-axis...
December 2018: Topics in Companion Animal Medicine
Elise Springer, S Barron Frazier, Donald H Arnold, Adam A Vukovic
BACKGROUND: Computed tomography (CT) is frequently used to identify intra-abdominal injuries in children with blunt abdominal trauma (BAT). The Pediatric Emergency Care Applied Research Network (PECARN) proposed a prediction rule to identify children with BAT who are at very low risk for clinically-important intra-abdominal injuries (CIIAI) in whom CT can be avoided. OBJECTIVE: To determine the sensitivity of this prediction rule in identifying patients at very low risk for CIIAI in our pediatric trauma registry...
November 23, 2018: American Journal of Emergency Medicine
Beate Mayer, Julia Müller, María-José Candela-García, Annie-Claude Manteau, Christof Weinstock, Axel Pruß
Background: Transfusion emergencies and critical situations require specifically designed devices to simplify and optimize the standard procedures. In addition, matching antigens over and above ABO-Rh-K would be beneficial. Methods: Routine blood samples were collected in four immunohematology centers and tested with the new MDmulticard Basic Extended Phenotype for the simultaneous detection of the Duffy, Kidd, and Ss antigens, according to the principle of the lateral flow...
October 2018: Transfusion Medicine and Hemotherapy
Chao-Wei Lee, Hsin-I Tsai, Hao-Tsai Cheng, Wei-Ting Chen, Heng-Yuan Hsu, Chien-Chih Chiu, Yi-Ping Liu, Tsung-Han Wu, Ming-Chin Yu, Wei-Chen Lee, Miin-Fu Chen
BACKGROUND: Laparoscopic liver resection has been regarded as the standard treatment for liver tumors located at the left lateral liver sector. However, few studies have reported the results of laparoscopic left lateral sectionectomy (LLS) for HCC, not to mention the feasibility of this emerging technique for the less experienced liver surgeons. The current study would reappraise the Louisville statement by examining the outcome of LLS performed by a young liver surgeon. METHODS: We retrospectively reviewed two separate groups of patients who underwent open or laparoscopic left lateral sectionectomies at Chung Gung Memorial Hospital, Linkou...
November 28, 2018: BMC Gastroenterology
Mohamed Eldeiry, Christian Ghincea, Muhammad Aftab, Joseph C Cleveland, David Fullerton, Thomas Brett Reece
BACKGROUND: Innominate artery cannulation has gained some popularity over the last decade as an alternative to axillary artery cannulation for providing selective antegrade cerebral perfusion during repair of the ascending aorta and arch. Innominate artery cannulation provides several advantages including avoidance of an additional incision and use of a larger caliber artery to provide less resistance to high flow during bypass and selective antegrade cerebral perfusion. We hypothesize that these advantages make innominate artery cannulation superior to axillary artery cannulation as it can decrease operative times and potentially decrease blood loss...
December 2018: Journal of Surgical Research
Ibrahim Abdelazim, Ahmed Alanwar, Shikanova Svetlana, Kanshaiym Sakiyeva, Mohamed Farghali, Mohamed Mohamed, Gulmira Zhurabekova, Bakyt Karimova
BACKGROUND: The rate of multiple cesarean sections is persistently on the rise because of cultural demands for large families, and multiple cesarean sections are an important cause of maternal morbidity and mortality. OBJECTIVES: This study was designed to detect the complications associated with higher order compared to lower order cesarean sections. MATERIALS AND METHODS: The hospitals record of women who had a cesarean section performed after three or more previous cesarean sections, and those who had a cesarean section for the second time over 2 years reviewed...
November 21, 2018: Journal of Maternal-fetal & Neonatal Medicine
Marius Roman, Fausto Biancari, Aamer B Ahmed, Seema Agarwal, Leon Hadjinikolaou, Ali Al-Sarraf, Geoff Tsang, Aung Y Oo, M Field, Francesco Santini, Giovanni Mariscalco
BACKGROUND: Prothrombin complex concentrate (PCC) has recently emerged as effective alternative to fresh frozen plasma (FFP) in treating excessive perioperative bleeding. We performed a systematic review and meta-analysis to evaluate the safety and efficacy of PCC administration as first-line treatment for coagulopathy following adult cardiac surgery. METHODS: We searched PubMed/MEDLINE, EMBASE, and the Cochrane Library from inception to the end of March 2018 to identify eligible articles...
November 17, 2018: Annals of Thoracic Surgery
(no author information available yet)
BACKGROUND: Epistaxis is a common emergency presentation to ENT. The 'Epistaxis 2016: national audit of management' collected prospective data over a 30-day audit window in 113 centres. A 30-day all-cause mortality rate of 3.4 per cent was identified. This study examines in more detail the subgroup of patients who died during the audit period. METHODS: There were 985 eligible patients identified. Of these, 33 patients died within the audit period. World Health Organization bleeding score, Modified Early Warning System score, haemostasis time, source of referral, co-morbidities and cause of death were investigated from the dataset...
November 20, 2018: Journal of Laryngology and Otology
Johann P Hreinsson, Ragna Sigurdardottir, Sigrun H Lund, Einar S Bjornsson
OBJECTIVES: Lower gastrointestinal bleeding (LGIB) risk scores have mainly focused on identifying high-risk patients. A risk score aimed at predicting which patients will not require hospital-based intervention may reduce unnecessary hospital admissions. The aim of the current study was to develop such a risk score. MATERIAL AND METHODS: A retrospective, population-based study that included patients presenting to the emergency room (ER) with LGIB from 2010 to 2013...
November 20, 2018: Scandinavian Journal of Gastroenterology
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