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https://www.readbyqxmd.com/read/29348901/prevalence-and-risk-factors-of-lower-urinary-tract-symptoms-in-chinese-adult-men-a-multicentre-cross-sectional-study
#1
Meng Rao, Huangfang Shangguan, Zhengyan Zeng, Yi Zheng, Huiping Zhang, Honggang Li, Wei Xia, Changhong Zhu, Chengliang Xiong, Huangtao Guan
There has been no previous population-based study reporting the prevalence and risk factors of male lower urinary tract symptoms (LUTS) among men in mainland China. This cross-sectional study was conducted from 2013 to 2014 in three representative provinces of China: Guangdong, Hubei and Jiangsu. 3250 individuals participated in the interviews, which involved a questionnaire covering sociodemographic characteristics, lifestyle, dietary patterns and the International Prostate Symptom Score (IPSS). Blood was collected for lipids, glucose, insulin and reproductive hormone tests...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29343910/urodynamic-outcomes-of-tamsulosin-in-the-treatment-of-primary-bladder-neck-obstruction-in-men
#2
Manoj K Sudrania, Anuj Deep Dangi, Santosh Kumar, Barath Kumar, Nitin S Kekre
Introduction: Alpha blockers are widely used in the treatment of primary bladder neck obstruction; however, evidence for objective urodynamic efficacy is scarce. We studied the effect of the uroselective α1-blocker tamsulosin on urodynamic parameters in male patients with type I primary bladder neck obstruction. Methods: A single center prospective observational study was carried out from July 2013 to February 2015. Male patients (18-50 years) with type 1 primary bladder neck obstruction were recruited...
January 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29341503/tadalafil-5-mg-once-daily-improves-lower-urinary-tract-symptoms-and-erectile-dysfunction-a-systematic-review-and-meta-analysis
#3
Yilin Wang, Yiping Bao, Jie Liu, Lijun Duan, Yuanshan Cui
OBJECTIVES: We carried out a systematic review and meta-analysis to assess tadalafil 5 mg once-daily for the treatment of lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). METHODS: A literature review was performed to identify all published randomized double-blind, placebo-controlled trials of tadalafil 5 mg once-daily for the treatment of LUTS and ED. The search included the following databases: MEDLINE, EMBASE, and the Cochrane Controlled Trials Register...
January 2018: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/29341501/tadalafil-improves-symptoms-erectile-function-and-quality-of-life-in-patients-with-lower-urinary-tract-symptoms-suggestive-of-benign-prostatic-hyperplasia-kyu-pro-study
#4
Ryosuke Takahashi, Minoru Miyazato, Hisae Nishii, Yasuhiro Sumino, Kazuo Takayama, Masako Onzuka, Takuma Oshiro, Seiichi Saito, Naohiro Fujimoto, Hiromitsu Mimata, Masatoshi Eto
OBJECTIVES: Effect of tadalafil on lower urinary tract symptoms (LUTS), erectile function and quality of life (QoL) were prospectively evaluated in patients with benign prostatic hyperplasia (BPH) at multicenter. METHODS: Eligible men were ≥40 years who had no treatment with alpha-blocker for BPH, with total International Prostate Symptom Score (IPSS) ≥8, IPSS-QOL ≥2 and prostate volume ≥20 mL. Data were collected on age, body mass index (BMI), and prostate specific antigen (PSA)...
January 2018: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/29333515/changes-in-autonomic-nervous-system-activity-after-treatment-with-alpha-blocker-in-men-with-lower-urinary-tract-symptoms
#5
Kang Hee Shim, Tae Woo Kim, Byung Ha Chung, Sung Won Lee, Jong Kwan Park, Kwangsung Park, Jun Cheon, Kyung Seop Lee, Hyung-Jee Kim, Do-Hwan Seong, Seung-June Oh, Sae Woong Kim, Ji Youl Lee, Seol Ho Choo, Jong Bo Choi
Purpose: To determine changes in autonomic nervous system activity after treatment in men with lower urinary tract symptoms (LUTS), we evaluated changes in patients' symptoms, uroflowmetry, and heart rate variability (HRV) after treatment with alpha-blockers for 12 weeks. Materials and Methods: Ninety-five men who had LUTS (International Prostate Symptom Score [IPSS] ≥8) were included in this study. We divided them into two groups on the basis of a low frequency/high frequency (LF/HF) ratio of 1...
January 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29330000/histotripsy-treatment-of-benign-prostatic-enlargement-using-the-vortx-rx-system-initial-human-safety-and-efficacy-outcomes
#6
T G Schuster, J T Wei, K Hendlin, R Jahnke, W W Roberts
OBJECTIVES: To assess clinical safety (primary) and efficacy (secondary) of histotripsy for treatment of symptomatic benign prostatic enlargement (BPE) in a first-in human study. METHODS: Twenty-five male subjects with moderate to severe lower urinary tract symptoms (LUTS), prostate size between 30 and 80 grams and no evidence of prostate cancer were enrolled at two sites in a prospective, single-arm study. Treatment consisted of acoustic energy delivery through the perineum with integrated real-time TRUS monitoring using the Vortx RX system...
January 9, 2018: Urology
https://www.readbyqxmd.com/read/29329896/open-prostatectomy-versus-180-w-xps-greenlight-laser-vaporization-long-term-functional-outcome-for-prostatic-adenomas-80%C3%A2-g
#7
C Lanchon, G Fiard, J-A Long, V Arnoux, D Carnicelli, Q Franquet, D Poncet, E Bey, J-B Lefrancq, S Grisard, N Peilleron, N Terrier, B Boillot, J-J Rambeaud, J-L Descotes, C Thuillier
INTRODUCTION: GreenLight photoselective vaporisation of the prostate (PVP) offers an endoscopic alternative to open prostatectomy (OP) for treatment of large adenomas. This study compares long-term functional outcome of both techniques in patients with Benign prostatic obstruction (BPO)>80g. MATERIAL AND METHOD: Data from patients who underwent surgical treatment for BPO>80g from January 2010 to February 2015 at our institution were retrospectively collected and compared according to surgical technique...
January 9, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29329895/long-term-outcomes-of-laser-prostatectomy-for-storage-symptoms-comparison-of-serial-5-year-follow-up-data-between-120w-hps-photo-selective-vaporization-of-the-prostate-and-holmium-laser-enucleation-of-the-prostate
#8
Min Chul Cho, Won Hoon Song, Juhyun Park, Sung Yong Cho, Hyeon Jeong, Seung-June Oh, Jae-Seung Paick, Hwancheol Son
PURPOSE: To compare long-term outcomes for storage symptoms between PVP-120W-HPS and HoLEP, and to find factors influencing postoperative improvement of storage symptoms in the long term. MATERIALS AND METHODS: A total of 266 men (PVP-120W-HPS group, 165; HoLEP group, 101), for whom 60-month follow-up data were available, were included in our study. Outcomes were assessed serially at 6-, 12- 24-, 36-, 48-, and 60-months postoperatively, using the IPSS, uroflowmetry, and serum PSA level...
January 9, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29319919/outcomes-and-toxicities-in-intermediate-risk-prostate-cancer-patients-treated-with-brachytherapy-alone-or-brachytherapy-and-supplemental-external-beam-radiation-therapy
#9
Emily Schlussel Markovic, Michael Buckstein, Nelson N Stone, Richard G Stock
OBJECTIVE: To evaluate the cancer control outcomes and long-term treatment-related morbidity of brachytherapy as well as combination brachytherapy and EBRT in patients with intermediate-risk prostate cancer. MATERIALS AND METHODS: A retrospective review was conducted in a prospectively collected database of patients with intermediate-risk prostate cancer who were treated either with brachytherapy or brachytherapy and EBRT, with or without ADT, from 1990-2014. Urinary and erectile dysfunction symptoms are measured using the International Prostate Symptom Score (IPSS) and the Mount Sinai erectile function scale, and the Sexual Health Inventory for Men (SHIM), respectively...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29319914/aquablation-therapy-for-symptomatic-benign-prostatic-hyperplasia-single-center-experience-in-47-patients
#10
Mihir M Desai, Abhishek Singh, Shashank Abhishek, Abhishek Laddha, Harshad Pandya, Akbar N Ashrafi, Arvind P Ganpule, Claus G Roehrborn, Andrew J Thomas, Mahesh Desai, Ravindra B Sabnis
OBJECTIVE: To report procedure process improvements and confirm preserved safety and short-term effectiveness of a second-generation Aquablation device for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) in 47 consecutive patients at a single institution. PATIENTS AND METHODS: Aquablation was performed in 47 patients with symptomatic BPH at a single institution. Baseline, perioperative and 3-month urinary function data were collected...
January 10, 2018: BJU International
https://www.readbyqxmd.com/read/29315267/experimental-evaluation-of-uwb-indoor-positioning-for-sport-postures
#11
Matteo Ridolfi, Stef Vandermeeren, Jense Defraye, Heidi Steendam, Joeri Gerlo, Dirk De Clercq, Jeroen Hoebeke, Eli De Poorter
Radio frequency (RF)-based indoor positioning systems (IPSs) use wireless technologies (including Wi-Fi, Zigbee, Bluetooth, and ultra-wide band (UWB)) to estimate the location of persons in areas where no Global Positioning System (GPS) reception is available, for example in indoor stadiums or sports halls. Of the above-mentioned forms of radio frequency (RF) technology, UWB is considered one of the most accurate approaches because it can provide positioning estimates with centimeter-level accuracy. However, it is not yet known whether UWB can also offer such accurate position estimates during strenuous dynamic activities in which moves are characterized by fast changes in direction and velocity...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29307684/development-of-a-nationally-representative-coordinated-registry-network-for-prostate-ablation-technologies
#12
Ron Golan, Adrien Bernstein, Art Sedrakyan, Timothy J Daskivich, Dongyi T Du, Behfar Ehdaie, Benjamin Fisher, Michael A Gorin, Ivan Grunberger, Bradley Hunt, Hongying H Jiang, Hyung L Kim, Danica Marinac-Dabic, Leonard S Marks, Timothy D McClure, Jeffrey S Montgomery, Dipen J Parekh, Sanoj Punnen, Stephen Scionti, Charles J Viviano, John T Wei, Sven Wenske, James S Wysock, John Rewcastle, Mark Carol, Marc Oczachowski, Jim C Hu
BACKGROUND: The accumulation of data through a prospective, multi-center coordinated registry network (CRN) is a practical way to gather real world evidence on the performance of novel prostate ablation technologies. Urologic oncologists, targeted biopsy experts, industry representatives, and the Food and Drug Administration (FDA) convened to discuss the role, feasibility, and important data elements of a CRN to assess new and existing prostate ablation technologies. METHODS: A multi-round Delphi consensus approach was performed which included the opinion of 15 expert urologists, representatives of the FDA and leadership from HIFU device manufacturers...
January 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29307091/low-pressure-monopolar-electroresection-of-the-prostate-for-glands-sized%C3%A2-%C3%A2-70-vs-%C3%A2-%C3%A2-70%C3%A2-cc-performed-with-continuous-irrigation-and-suprapubic-suction-perioperative-and-long-term-outcome
#13
Konrad Wilhelm, Ioana Maria Cazana, Martin Schoenthaler, Arndt Katzenwadel, Johannes Spaeth, Arkadiusz Miernik
PURPOSE: To evaluate long-term efficacy and safety of low-pressure transurethral resection of the prostate for prostates < 70 cc (group 1) vs. > 70 cc (group 2). PATIENTS AND METHODS: In this study patients operated with monopolar TURP between 2009 and 2012 were evaluated retrospectively. During surgery a specially designed trocar (18 Fr) was placed suprapubically and connected to a suction pump to maintain stable low-pressure conditions. After sample size calculations, long-term follow-up was completed for 70 invited patients in each group up to 9/2015...
January 6, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29304808/prospective-longitudinal-outcomes-of-quality-of-life-after-laparoscopic-radical-prostatectomy-compared-with-retropubic-radical-prostatectomy
#14
Katsuyoshi Hashine, Toshio Kakuda, Shunsuke Iuchi, Tadanori Hosokawa, Iku Ninomiya
BACKGROUND: There have been few reports on health-related quality of life (HRQOL) after laparoscopic radical prostatectomy (LRP) in Japanese patients. The aim of this study is to assess changes in HRQOL during 36 months after LRP compared with retropubic radical prostatectomy (RRP). METHODS: The subjects were 105 consecutive patients treated with LRP between 2011 and 2012. HRQOL was evaluated using the International Prostate Symptom Score (IPSS), Medical Outcome Study 8-Items Short Form Health Survey (SF-8), and Expanded Prostate Cancer Index Composite (EPIC) at baseline and 1, 3, 6, 12 and 36 months after surgery...
January 5, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29296792/a-4-lncrna-scoring-system-for-prognostication-of-adult-myelodysplastic-syndromes
#15
Chi-Yuan Yao, Ching-Hsuan Chen, Huai-Hsuan Huang, Hsin-An Hou, Chien-Chin Lin, Mei-Hsuan Tseng, Chein-Jun Kao, Tzu-Pin Lu, Wen-Chien Chou, Hwei-Fang Tien
Long noncoding RNAs (lncRNAs) not only participate in normal hematopoiesis but also contribute to the pathogenesis of acute leukemia. However, their clinical and prognostic relevance in myelodysplastic syndromes (MDSs) remains unclear to date. In this study, we profiled lncRNA expressions in 176 adult patients with primary MDS, and identified 4 lncRNAs whose expression levels were significantly associated with overall survival (OS). We then constructed a risk-scoring system with the weighted sum of these 4 lncRNAs...
August 22, 2017: Blood Advances
https://www.readbyqxmd.com/read/29286224/utility-of-5-methylcytosine-immunohistochemical-staining-to-assess-global-dna-methylation-and-its-prognostic-impact-in-mds-patients
#16
Dinesh Chandra, Seema Tyagi, Jasdeep Singh, Roopam Deka, Prabhu Manivannan, Pravas Mishra, Hara Prasad Pati, Renu Saxena
Background: DNA methylation plays a vital role in the pathogenesis of the myelodysplastic syndrome (MDS), a heterogeneous group of clonal hematopoietic stem cell (HSC) disorders. It is reported to be an independent prognostic factor affecting overall survival (OS). Our aim was to analyze the role of global DNA methylation using an anti-5-methylcytosine (5-MC) antibody by immunohistochemistry (IHC) of bone marrow biopsy (BM Bx) specimens in MDS patients, assessing correlations with various clinical and biological prognostic factors...
December 29, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29283083/the-risk-of-urinary-retention-following-robot-assisted-radical-prostatectomy-and-its-impact-on-early-continence-outcomes
#17
Mansour Alnazari, Marc Zanaty, Khaled Ajib, Assaad El-Hakim, Kevin C Zorn
INTRODUCTION: We aimed to evaluate the risk factors of acute urinary retention (AUR) following robot-assisted radical prostatectomy (RARP), as well as the relationship of AUR with early continence outcomes. METHODS: The records of 740 consecutive patients who underwent RARP by two experienced surgeons at our institution were retrospectively reviewed from a prospectively collected database. Multiple factors, including age, body mass index (BMI), international prostate symptom score (IPSS), prostate volume, presence of median lobe, nerve preservation status, anastomosis time, and catheter removal time (Day 4 vs...
December 22, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29282358/convective-radiofrequency-water-vapor-thermal-therapy-for-benign-prostatic-hyperplasia-a-single-office-experience
#18
Daniel Mollengarden, Kenneth Goldberg, Daniel Wong, Claus Roehrborn
BACKGROUND: Convective radiofrequency water vapor thermal therapy with the Rezūm system is a relatively new treatment for benign prostatic hyperplasia (BPH). We present results from a single surgeon in an office setting. METHODS: A retrospective review of 129 patients from a single surgeon who underwent the Rezūm procedure was performed. All patients were at least 4 months out from treatment. International prostate symptom scores (IPSS), maximum flow rates (Qmax), residual urine volumes, medication usage, and adverse events were monitored...
December 27, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/29275506/safety-and-efficacy-using-a-low-powered-holmium-laser-for-enucleation-of-the-prostate-holep-12-month-results-from-a-prospective-low-power-holep-series
#19
B Becker, A J Gross, C Netsch
PURPOSE: To analyze the 12-month outcomes of low-powered holmium laser enucleation of the prostate (LP-HoLEP) for patients with symptomatic benign prostatic obstruction (BPO). METHODS: A total of 54 patients with symptomatic BPO were treated with LP-HoLEP. All patients were treated by two experienced LP-HoLEP surgeons. A 50-W Ho:YAG laser was used at 39.6-W (2.2 J, 18 Hz). All patients were assessed preoperatively by International Prostate Symptom Score (IPSS), quality of life (QoL), maximum flow rate (Qmax), post-void residual urine (PVR), PSA, and whole prostate volume measurement by transrectal ultrasound...
December 23, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29239228/comparison-of-holmium-laser-enucleation-and-plasmakinetic-resection-of-prostate-a-randomized-trial-with-72-month-follow-up
#20
Meng Gu, Yan-Bo Chen, Chong Liu, Xiang Wan, Zhi-Kang Cai, Qi Chen, Zhong Wang
PURPOSE: To evaluate the long-term and flexible cystourethroscopy results of holmium laser enucleation of the prostate (HoLEP) and to compare them with those of plasmakinetic resection of the prostate (PKRP). METHODS: In the long-term follow-up, variables, including the international prostatic symptomatic score (IPSS), quality of life (QoL) scores, maximum flow rate (Qmax) and international index of erectile function (IIEF), and the adverse events, including the need for retreatment, were specifically assessed...
December 14, 2017: Journal of Endourology
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