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https://www.readbyqxmd.com/read/28740902/urinary-quality-of-life-outcomes-in-men-who-were-treated-with-image-guided-intensity-modulated-radiation-therapy-for-prostate-cancer
#1
Simpa S Salami, Edward Obedian, Shawn Zimberg, Carl A Olsson
PURPOSE: Quality of life (QoL) outcomes play a major role in the treatment selection for prostate cancer (CaP). We evaluated the urinary QoL outcomes in men who were treated with image-guided intensity-modulated radiation therapy (IG-IMRT) for CaP. METHODS AND MATERIALS: We enrolled men who were diagnosed with CaP and underwent IG-IMRT in a large urological group practice into a prospectively maintained database. The typical radiation treatment dosage to prostates and seminal vesicles was 8100 cGy in 45 fractions...
October 2016: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28731510/the-association-of-lower-urinary-tract-symptoms-with-incidental-falls-and-fear-of-falling-in-later-life-the-community-health-survey
#2
Kyu Shik Kim, Ji Won Nam, Bo Youl Choi, Hong Sang Moon
AIM: To evaluate the association between lower urinary tract symptoms (LUTS) and incidental falls and fear of falling. METHODS: We used data obtained from the 2011 Korean Community Health Survey (KCHS) conducted between August and October 2011 in South Korea. The survey was carried out to estimate patterns of disease prevalence and morbidity in men >40 years old. The trained interviewers performed face-to-face sociodemographic questionnaires using computer-assisted personal interviewing (CAPI) software, the International Prostate Symptom Score (IPSS), the Quality of Life score (EQ-5D), and a questionnaire about past falls and fear of falling...
July 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28728990/long-term-testosterone-therapy-improves-urinary-and-sexual-function-and-quality-of-life-in-men-with-hypogonadism-results-from-a-propensity-matched-subgroup-of-a-controlled-registry-study
#3
Karim Sultan Haider, Ahmad Haider, Gheorghe Doros, Abdulmaged Traish
OBJECTIVES: To investigate the effects of long-term testosterone (T) therapy (TTh) on urinary and sexual functions and quality of life (QoL) in hypogonadal men. PATIENTS AND METHODS: Observational, prospective, cumulative registry study in 656 men (age: 60.7 ± 7.2 years) with total T levels ≤12.1 nmol/L and symptoms of hypogonadism. In the T-treated group, men (n = 360) received parenteral T undecanoate (TU) 1000 mg/12 weeks for up to 10 years. Men who opted against TTh (n= 296) served as controls...
July 17, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28721281/safety-and-efficacy-of-tamsulosin-alfuzosin-or-silodosin-as-monotherapy-for-luts-in-bph-a-double-blind-randomized-trial
#4
Chikka Moga Siddaiah Manohar, Mahadevappa Nagabhushana, Vilvapathy Senguttuvan Karthikeyan, Ramachandra Pudakalkatti Sanjay, Ananth Janardhan Kamath, Ramaiah Keshavamurthy
INTRODUCTION: Currently alpha1-adrenoceptor blockers (AB) are widely used as first-line therapy to improve lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). We compared the efficacy and safety profile of tamsulosin, alfuzosin and silodosin in LUTS due to BPH. MATERIAL AND METHODS: Consecutive consenting male patients (N = 269) undergoing medical management of BPH with AB from February 2012 to October 2015 were enrolled. Patients were randomized to a 0...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28717651/comparison-of-nonspherical-polyvinyl-alcohol-particles-and-microspheres-for-prostatic-arterial-embolization-in-patients-with-benign-prostatic-hyperplasia
#5
Jin Ho Hwang, Sang Woo Park, Il Soo Chang, Sung Il Jung, Hae Jeong Jeon, Yong Soo Lho, Hyeong Gon Kim, Sung Hyun Paick, Hyoung Keun Park
PURPOSE: To report early results following prostatic artery embolization (PAE) and compare outcomes between nonspherical polyvinyl alcohol (PVA) particles and microspheres to treat lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). METHODS: PAE was performed in nine patients (mean age: 78.1 years) with symptomatic BPH. Embolization was performed using nonspherical PVA particles (250-355 μm) in four patients and microspheres (300-500 μm) in five patients...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28717543/outcome-analysis-of-transurethral-resection-versus-potassium-titanyl-phosphate-photo-selective-vaporization-of-the-prostate-for-the-treatment-of-benign-prostatic-hyperplasia-a-randomized-controlled-trial-with-4-years-follow-up
#6
Bimalesh Purkait, Rahul Janak Sinha, Krishna Swamy A Srinivas, Ankur Bansal, Ashok Kumar Sokhal, Vishwajeet Singh
OBJECTIVE: Photovaporization of prostate (PVP) is a newer surgical modality of benign prostatic hyperplasia (BPH) which is gaining importance recently. There are a few randomized controlled trials that showed safety and efficacy of PVP in comparison with transurethral resection of prostate (TURP) with limited follow-up period (<2 years). Here, we are presenting a comparative study performed on potassium titanyl phosphate (KTP) PVP laser versus TURP for the treatment of BPH with long-term follow-up period...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28711920/baseline-factors-associated-with-response-to-ruxolitinib-an-independent-study-on-408-patients-with-myelofibrosis
#7
REVIEW
Francesca Palandri, Giuseppe Alberto Palumbo, Massimiliano Bonifacio, Mario Tiribelli, Giulia Benevolo, Bruno Martino, Elisabetta Abruzzese, Mariella D'Adda, Nicola Polverelli, Micaela Bergamaschi, Alessia Tieghi, Francesco Cavazzini, Adalberto Ibatici, Monica Crugnola, Costanza Bosi, Roberto Latagliata, Ambra Di Veroli, Luigi Scaffidi, Federico de Marchi, Elisa Cerqui, Barbara Anaclerico, Giovanna De Matteis, Marco Spinsanti, Elena Sabattini, Lucia Catani, Franco Aversa, Francesco Di Raimondo, Umberto Vitolo, Roberto Massimo Lemoli, Renato Fanin, Francesco Merli, Domenico Russo, Antonio Cuneo, Maria Letizia Bacchi Reggiani, Michele Cavo, Nicola Vianelli, Massimo Breccia
In patients with Myelofibrosis (MF) treated with ruxolitinib (RUX), the response is unpredictable at therapy start. We retrospectively evaluated the impact of clinical/laboratory factors on responses in 408 patients treated with RUX according to prescribing obligations in 18 Italian Hematology Centers. At 6 months, 114 out of 327 (34.9%) evaluable patients achieved a spleen response. By multivariable Cox proportional hazard regression model, pre-treatment factors negatively correlating with spleen response were: high/intermediate-2 IPSS risk (p=0...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28710830/prognostic-significance-of-a-comprehensive-histologic-evaluation-of-reticulin-fibrosis-collagen-deposition-and-osteosclerosis-in-primary-myelofibrosis-patients
#8
Umberto Gianelli, Stefano Fiori, Daniele Cattaneo, Anna Bossi, Ivan Cortinovis, Arturo Bonometti, Giulia Ercoli, Cristina Bucelli, Nicola Orofino, Gaetano Bulfamante, Alessandra Iurlo
AIMS: to evaluate whether a comprehensive histological evaluation of reticulin fibrosis, collagen deposition and osteosclerosis in bone marrow trephine biopsies (BMBs) of primary myelofibrosis (PMF) patients may have prognostic implications. METHODS: reticulin fibrosis, collagen deposition and osteosclerosis were graded from 0 to 3 in a series of 122 base-line BMBs. Then, we assigned to each case a comprehensive score (RCO score, ranging from 0 to 9) that allowed us to distinguish two groups of patients, with low-grade (RCO score 0-4) and high-grade (RCO score 5-9) stromal changes...
July 15, 2017: Histopathology
https://www.readbyqxmd.com/read/28701725/prospective-study-on-association-of-prostatic-calcifications-with-clinical-symptoms-and-results-of-treatment-in-men-with-type-iii-prostatitis
#9
Xiang Fei, Wei Jin, Shengyu Hua, Yan Song
The purpose is to investigate the clinical significance of prostatic calculi in patients with chronic prostatitis and to discuss the possible treatment.The data from 277 young males with CP/CPPS were analyzed prospectively. Symptom severity was measured using the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) and the International Prostatic Symptoms Score (IPSS). Sexual function was assessed by the International Index of Erectile Function (IIEF-5) questionnaire. After four weeks of therapy, the NIH-CPSI, IPSS, and IIEF-5 tests were repeated...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28687936/prevalence-of-lower-urinary-tract-symptoms-in-china-taiwan-and-south-korea-results-from-a-cross-sectional-population-based-study
#10
Christopher Chapple, David Castro-Diaz, Yao-Chi Chuang, Kyu-Sung Lee, Limin Liao, Shih-Ping Liu, Jianye Wang, Tag Keun Yoo, Romeo Chu, Budiwan Sumarsono
INTRODUCTION: Few population-based data are available evaluating the prevalence of lower urinary tract symptoms (LUTS) in Asia. The objective of our study was to determine LUTS prevalence in China, Taiwan, and South Korea using International Continence Society (ICS) 2002 criteria. METHODS: An Internet-based self-administered survey among individuals aged at least 40 years with the ability to use a computer and to read the local language. Survey questions included ICS symptom definitions and the international prostate symptom score (IPSS)...
July 7, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28685201/longitudinal-changes-in-erectile-function-after-thulium-yag-prostatectomy-for-the-treatment-of-benign-prostatic-obstruction-a-1-year-follow-up-study
#11
Jae Seung Chung, Sang Hyun Park, Cheol Kyu Oh, Seong Cheol Kim, Taek Sang Kim, Pil Moon Kang, Won Ik Seo, Wan Seok Kim, Jang Ho Yoon, Dong Ii Kang, Kweon Sik Min, Jae Ii Chung
This study aimed to evaluate the impact of thulium:yttrium-aluminum-garnet (Tm:YAG) (RevoLix®) laser prostatectomy for the treatment of benign prostatic obstructions on erectile function (EF). A total of 208 patients who underwent Tm:YAG laser prostatectomies participated in this study. All cases were evaluated preoperatively and at 3, 6, and 12 months postoperatively using the International Prostate Symptom Score (IPSS), quality of life (QoL) score, and the International Index of Erectile Function (IIEF-5) questionnaires...
July 6, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28677895/overall-survival-in-lower-ipss-risk-mds-by-receipt-of-iron-chelation-therapy-adjusting-for-patient-related-factors-and-measuring-from-time-of-first-red-blood-cell-transfusion-dependence-an-mds-can-analysis
#12
Heather A Leitch, Ambica Parmar, Richard A Wells, Lisa Chodirker, Nancy Zhu, Thomas J Nevill, Karen W L Yee, Brian Leber, Mary-Margaret Keating, Mitchell Sabloff, Eve St Hilaire, Rajat Kumar, Robert Delage, Michelle Geddes, John M Storring, Andrea Kew, April Shamy, Mohamed Elemary, Martha Lenis, Alexandre Mamedov, Jessica Ivo, Janika Francis, Liying Zhang, Rena Buckstein
Analyses suggest iron overload in red blood cell (RBC) transfusion-dependent (TD) patients with myleodysplastic syndrome (MDS) portends inferior overall survival (OS) that is attenuated by iron chelation therapy (ICT) but may be biassed by unbalanced patient-related factors. The Canadian MDS Registry prospectively measures frailty, comorbidity and disability. We analysed OS by receipt of ICT, adjusting for these patient-related factors. TD International Prognostic Scoring System (IPSS) low and intermediate-1 risk MDS, at RBC TD, were included...
July 5, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28675513/itaca-a-new-validated-international-erythropoietic-stimulating-agent-response-score-that-further-refines-the-predictive-power-of-previous-scoring-systems
#13
Rena Buckstein, Enrico Balleari, Richard Wells, Valeria Santini, Alessandro Sanna, Chiara Salvetti, Elena Crisà, Bernardino Allione, Paolo Danise, Carlo Finelli, Marino Clavio, Antonella Poloni, Flavia Salvi, Daniela Cilloni, Esther Natalie Oliva, Pellegrino Musto, Brett Houston, Nancy Zhu, Michelle Geddes, Heather Leitch, Brian Leber, Mitchell Sabloff, Thomas J Nevill, Karen Yee, John M Storring, Janika Francis, Luca Maurillo, Roberto Latagliata, Maria Antonietta Aloe Spiriti, Alessandro Andriani, Anna Lina Piccioni, Luana Fianchi, Susanna Fenu, Svitlana Gumenyuk, Francesco Buccisano
BACKGROUND: In 'real-life', the Nordic score guides ESA use in lower-risk MDS with predicted response rates of 25% or 74%. As new treatments emerge, a more discriminating score is needed. OBJECTIVES: To validate existing ESA predictive scores and develop a new score that identifies non-responders. METHODS: ESA-treated patients were identified in 3 MDS registries in Italy and Canada (FISM 555, GROM 233, MDS-CAN 208). Clinical and disease-related variables were captured...
July 4, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28674908/transperineal-reanastomosis-for-treatment-of-highly-recurrent-anastomotic-strictures-after-radical-retropubic-prostatectomy-extended-follow-up
#14
Victor Maximilian Schuettfort, Roland Dahlem, Luis Kluth, Daniel Pfalzgraf, Clemens Rosenbaum, Tim Ludwig, Margit Fisch, Christoph-Philip Reiss
OBJECTIVES: To re-evaluate safety and efficacy of transperineal reanastomosis (TPRA) as a viable therapeutic option in highly recurrent anastomotic strictures (AS) after radical retropubic prostatectomy (RRP). METHODS: Retrospective analysis by standardized questionnaire inquiring for recurrence of stricture, stress urinary incontinence (SUI), sexual function, satisfaction, and changes in quality of life (QoL) was performed in all patients undergoing TPRA. Validated questionnaires (ICIQ-UI, EQ-5D, and IPSS) were included...
July 3, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28673065/sociodemographic-factors-related-to-lower-urinary-tract-symptoms-in-men-a-korean-community-health-survey
#15
Jung Ki Jo, Kyu Shik Kim, Ji Won Nam, Bo Yul Choi, Hong Sang Moon
PURPOSE: This study estimated the prevalence of lower urinary tract symptoms (LUTS) in Korean men and the conditions for being diagnosed with or treated for LUTS/benign prostatic hyperplasia (BPH). METHODS: We analyzed cross-sectional data collected from 69,851 Korean men who were 40 years of age or older and had participated in the Korean Community Health Survey performed in 2011. Interviewers performed face-to-face surveys that included sociodemographic questions, the International Prostate Symptom Score (IPSS), and questions regarding whether the subjects had been diagnosed with or treated for LUTS/BPH...
June 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28669578/prognostic-evaluation-of-alip-and-cd34-immunostaining-in-ipss-r-subgroups-of-myelodysplastic-syndromes
#16
Bei Xiong, Yanbo Nie, Zehai Tang, Mei Xue, Xuelan Zuo
In order to evaluate the prognostic value of abnormal localisation of immature precursors (ALIP) and CD34 immunostaining in myelodysplastic syndromes (MDS), bone marrow histopathological features in 187 MDS patients were retrospectively analysed and the prognostic significance of ALIP and CD34 immunostaining on overall survival (OS) and progression to leukaemia-free survival (PFS) in total patients and different Revised-International Prognostic Scoring System (IPSS-R) subgroups were evaluated. In univariate analysis, age ≥60, ALIP, ≥5% CD34+ cells, CD34+ clusters and IPSS-R subgroups were associated with shorter OS (p = 0...
August 2017: Pathology
https://www.readbyqxmd.com/read/28666552/single-dose-high-dose-rate-brachytherapy-compared-to-two-and-three-fractions-for-locally-advanced-prostate-cancer
#17
Peter Hoskin, Ana Rojas, Peter Ostler, Robert Hughes, Roberto Alonzi, Gerry Lowe
BACKGROUND: Single-dose high-dose-rate brachytherapy (HDR-BT), in a Phase-II study, was compared to two or three fractions in intermediate and high-risk localized prostate cancer. PATIENTS AND METHODS: 293 patients received 1×19Gy or 1×20Gy (A=49), 2×13Gy (B=138), or 3×10.5Gy (C=106) and assessed with prospective measures of serum PSA, late genitourinary (GU) and gastrointestinal (GI) morbidity using RTOG scales and the International Prostate Symptom Score (IPSS)...
June 27, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28665320/dimension-reduced-analog-digital-mixed-measurement-method-of-inductive-proximity-sensor
#18
Yi-Xin Guo, Zhi-Biao Shao, Hui-Bin Tao, Kai-Liang Xu, Ting Li
Inductive proximity sensors (IPSs) present a unique no-contact advantage. They are widely preferred for displacement measurement in various industrial fields (e.g., aviation and aerospace), and they are improved continuously. When the inductance and resistance components of the IPS sensing core are separated, the influence of temperature drift on measurement can be eliminated. The complexity of online computation of component separation can be reduced using a two-dimensional look-up table method. However, this method exhibits disadvantages, such as large capacity of the look-up table, dependency on precision measurement of sensing core parameter, and nonlinear distribution of measurement resolution...
June 30, 2017: Sensors
https://www.readbyqxmd.com/read/28660750/urinary-manifestations-in-isaacs-s-syndrome-our-experience-in-8-cases
#19
Silvia N Gonzalez Primomo, Leandro Blas, Alicia C Bertotti, Carlos Ameri
INTRODUCTION: Isaacs's syndrome (IS), is a rare neurological disorder, characterized by sustained muscular activity, fasciculations, cramps, myokymia, excessive sweating, and occasional elevation of creatine phosphokinase (CPK) enzyme. AIM: To report our experience in patients with IS and urinary manifestations, describing clinical findings, test's results, and response to treatment. Methods An observational, retrospective analysis of patients with IS and urinary manifestations treated at German Hospital of Buenos Aires between 2001 and 2011 was done...
June 29, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28652878/randomized-controlled-trial-of-laser-vs-bipolar-plasma-vaporization-treatment-of-benign-prostatic-hyperplasia
#20
Thomas A A Skinner, Robert J Leslie, Stephen S Steele, J Curtis Nickel
INTRODUCTION: Prostate vaporization technology is becoming a standard of care for treatment of moderate, symptomatic benign prostatic hyperplasia (BPH). We compared two transurethral prostate vaporization technologies with respect to cost, efficiency, efficacy, safety, and surgical team satisfaction. METHODS: Fifty-five patients meeting standardized symptom criteria for BPH were randomized to either Olympus Plasma Button(TM) or Biolitec EVOLVE(®) diode laser vaporization...
June 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
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