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https://www.readbyqxmd.com/read/29221643/respiratory-and-cardiovascular-responses-to-walking-down-a-traffic-polluted-road-compared-with-walking-in-a-traffic-free-area-in-participants-aged-60-years-and-older-with-chronic-lung-or-heart-disease-and-age-matched-healthy-controls-a-randomised-crossover
#1
Rudy Sinharay, Jicheng Gong, Benjamin Barratt, Pamela Ohman-Strickland, Sabine Ernst, Frank Kelly, Junfeng Jim Zhang, Peter Collins, Paul Cullinan, Kian Fan Chung
BACKGROUND: Long-term exposure to pollution can lead to an increase in the rate of decline of lung function, especially in older individuals and in those with chronic obstructive pulmonary disease (COPD), whereas shorter-term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic heart disease and exacerbations of COPD. We aimed to assess the effects on respiratory and cardiovascular responses of walking down a busy street with high levels of pollution compared with walking in a traffic-free area with lower pollution levels in older adults...
December 5, 2017: Lancet
https://www.readbyqxmd.com/read/29221328/uncontrolled-and-under-diagnosed-asthma-in-a-damascus-shelter-during-the-syrian-crisis
#2
Yousser Mohammad, Shaaban Rafea, Youssef Latifeh, Ali Khaddam, Bisher Sawaf, Mhd Ismael Zakaria, Mohammad Sadek Al Masalmeh, Yaser Fawaz, Abdoulraouf Allaham, Imad Almani, Hiba El-Tarcheh, Ayham Ghazal, Ali Zaher, Hala Rifai, Hamed Joumah, S Dresden Glockler-Lauf, Teresa To
Background: Studies have shown that poor shelter or dwelling conditions may lead to deteriorations in health. Those with asthma may be more susceptible to compromised living conditions and stress leading to a higher risk of asthma exacerbations. To describe the asthma control and quality of life of individuals with diagnosed asthma living in a shelter in Damascus, Syria and estimate the prevalence of respiratory symptoms in shelter dwellers without diagnosed asthma. Methods: In this cross-sectional study, all individuals 5 years and older living in Al-Herjalleh shelter with diagnosed asthma were recruited to complete a questionnaire, which included items related to their respiratory symptoms, asthma exacerbations, exposure to asthma triggers, medication use, and health-related quality of life before and since entering the shelter...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29219619/prenatal-and-early-life-fructose-fructose-containing-beverages-and-mid-childhood-asthma
#3
Lakiea S Wright, Sheryl L Rifas-Shiman, Emily Oken, Augusto A Litonjua, Diane R Gold
RATIONALE: Cross-sectional studies have linked intake of high fructose corn syrup sweetened beverages with asthma in school children. OBJECTIVE: To examine associations of maternal prenatal and early childhood intake of sugar sweetened beverages and fructose with current asthma in mid-childhood (median 7.7years). METHODS: We assessed maternal pregnancy (1st and 2nd trimester average) and child (median 3.3years) intake of sugar sweetened beverages and total fructose using food frequency questionnaires in 1068 mother-child pairs from Project Viva, a prospective pre-birth cohort...
December 8, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29217805/paint-in-the-pipe-an-unusual-foreign-body
#4
Neha Garg, Natasha Gupta, Dheeraj Shah, Piyush Gupta
BACKGROUND: Foreign bodies in the airway can be a diagnostic and therapeutic challenge. CASE CHARACTERISTICS: 30-month-old girl with complaints of noisy and fast breathing following fall over a pile of sand. Sand was suctioned out by direct bronchoscopy. The child improved initially but condition worsened in next four days with marked stridor and wheeze. OBSERVATION: Imaging revealed elongated sharp radiodense opacity in the cervical region, suggestive of foreign body...
November 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29217600/asthma-phenotypes-do-cough-and-wheeze-predict-exacerbations-in-persistent-asthma
#5
Jaymin B Morjaria, Alan S Rigby, Alyn H Morice
Little is known of the long-term symptom profile in uncontrolled asthma and whether symptoms can predict distinct phenotypes. The primary objective of these analyses was to assess diurnal profile of cough and wheeze in an uncontrolled asthma population. Secondary outcomes were to examine how these symptom profiles influence response to treatment.Twice-daily electronically recorded data from 1701 patients were examined in relation to the population demographics. Reliever treatment with salbutamol was then compared with extra-fine beclometasone/formoterol maintenance and reliever therapy (MART)...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29217598/phenotypes-of-symptomatic-airways-disease-in-china-and-new-zealand
#6
James Fingleton, Kewu Huang, Mark Weatherall, Yanfei Guo, Stefan Ivanov, Piet Bruijnzeel, Hong Zhang, Wei Wang, Richard Beasley, Chen Wang
It is uncertain whether phenotypes of asthma and chronic obstructive pulmonary disease (COPD) vary between populations with different genetic and environmental characteristics. Here, our objective was to compare the phenotypes of airways disease in two separate populations.This was a cross-sectional observational study in adult populations from New Zealand and China. Participants aged 40-75 years who reported wheeze and breathlessness in the last 12 months were randomly selected from the general population and underwent detailed characterisation...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29216193/community-prevalence-of-chronic-respiratory-symptoms-in-rural-malawi-implications-for-policy
#7
Hastings T Banda, Rachael Thomson, Kevin Mortimer, George A F Bello, Grace B Mbera, Rasmus Malmborg, Brian Faragher, S Bertel Squire
BACKGROUND: No community prevalence studies have been done on chronic respiratory symptoms of cough, wheezing and shortness of breath in adult rural populations in Malawi. Case detection rates of tuberculosis (TB) and chronic airways disease are low in resource-poor primary health care facilities. OBJECTIVE: To understand the prevalence of chronic respiratory symptoms and recorded diagnoses of TB in rural Malawian adults in order to improve case detection and management of these diseases...
2017: PloS One
https://www.readbyqxmd.com/read/29210195/hair-nicotine-at-15-months-old-tobacco-exposure-and-wheeze-or-asthma-from-15-months-to-6-years-old
#8
Philip K Pattemore, Karen M Silvers, Chris M Frampton, Kristin Wickens, Tristram Ingham, David Fishwick, Julian Crane, G Ian Town, Michael J Epton
OBJECTIVE: To investigate the relationship between hair nicotine levels at 15 months of age and prior parent-reported smoking exposure, and the risk of wheezing and current asthma from 15 months to 6 years of age. STUDY DESIGN: We measured hair nicotine levels at 15 months of age in 376 of 535 infants enrolled in a prospective birth cohort in Christchurch, New Zealand. We obtained detailed information from parents about smoking exposure during pregnancy and in the home at 3 and 15 months of age...
December 6, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29210034/a-novel-wheeze
#9
E Perritt, A Dunlop
No abstract text is available yet for this article.
January 2018: Anaesthesia
https://www.readbyqxmd.com/read/29208079/asthma-control-lung-function-symptoms-and-corticosteroid-sparing-after-omalizumab-initiation-in-patients-with-allergic-asthma
#10
(no author information available yet)
BACKGROUND: Omalizumab is approved in patients with moderate-to-severe allergic asthma with symptoms uncontrolled, despite the mainstay therapy. OBJECTIVE: Electronic medical records (EMR) were used to increase the knowledge of omalizumab effectiveness in areal-world setting. METHODS: Patients with uncontrolled moderate-to-severe allergic asthma, ages greater than or equal to 12 years old, initiated on omalizumab (index date), with greater than or equal to 12 months of pre- and postindex data, were identified in an EMR data base...
December 5, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29207697/effects-of-organophosphorus-pesticides-on-cardiorespiratory-parameters-among-the-farmers
#11
Udayakumar Karthika Priyadharshini, Radhakrishnan Latha, Ukkirapandian Kavitha, Natarajan Nirmala
Introduction: Indiscriminate use and improper handling of synthetic pesticides in agriculture have resulted in serious problems such as asthma, wheeze and chronic bronchitis among the farmers. Though number of studies have been done on pesticide exposure and its effect on cardiorespiratory parameters in Northern India, only few studies were done in Southern India, thus this study was chosen. Aim: To find the cardiorespiratory changes in farm workers exposed to organophosphorus pesticides...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29206851/role-of-viral-coinfections-in-asthma-development
#12
Maria Luz Garcia-Garcia, Cristina Calvo, Sara Ruiz, Francisco Pozo, Victoria Del Pozo, Laura Remedios, Nadia Exposito, Ana Tellez, Inmaculada Casas
BACKGROUND: Viral respiratory infections, especially acute bronchiolitis, play a key role in the development of asthma in childhood. However, most studies have focused on respiratory syncytial virus or rhinovirus infections and none of them have compared the long-term evolution of single versus double or multiple viral infections. OBJECTIVE: Our aim was to compare the frequency of asthma development at 6-8 years in children with previous admission for bronchiolitis associated with single versus double or multiple viral infection...
2017: PloS One
https://www.readbyqxmd.com/read/29205659/role-of-montelukast-in-management-of-episodic-viral-wheeze
#13
Tristan W Harding, Anton Gm Harding
No abstract text is available yet for this article.
December 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29205654/strategies-for-treatment-of-pre-schoolers-with-episodic-viral-wheeze
#14
Tristan W Harding, Corey Driscoll, Conor C Hensey
No abstract text is available yet for this article.
December 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29197835/kombucha-is-a-cup-of-tea-good-for-you
#15
Ailsa Holbourn, Judith Hurdman
A 54-year-old asthmatic woman presented to hospital with a 10-day history of breathlessness. On examination, she was tachypnoeic with mild wheeze. She had preserved peak flows and was saturating at 100% on room air. Investigations revealed severe metabolic lactic acidosis. On further questioning, it transpired that she drank kombucha tea, which has been linked to lactic acidosis. She made a full recovery with supportive management and cessation of the tea.
December 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29196348/the-value-of-the-physical-examination-in-clinical-practice-an-international-survey
#16
Andrew T Elder, I Chris McManus, Alan Patrick, Kichu Nair, Louella Vaughan, Jane Dacre
A structured online survey was used to establish the views of 2,684 practising clinicians of all ages in multiple countries about the value of the physical examination in the contemporary practice of internal medicine. 70% felt that physical examination was 'almost always valuable' in acute general medical referrals. 66% of trainees felt that they were never observed by a consultant when undertaking physical examination and 31% that consultants never demonstrated their use of the physical examination to them...
December 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29196148/circulating-il-17-producing-mucosal-associated-invariant-t-cells-mait-are-associated-with-symptoms-in-children-with-asthma
#17
Guillaume Lezmi, Rola Abou Taam, Céline Dietrich, Lucienne Chatenoud, Jacques de Blic, Maria Leite-de-Moraes
IL-17 and mucosal-associated invariant T (MAIT) cells have been involved in asthma pathogenesis. However, IL-17-producing MAIT cells (MAIT-17) were not evidenced. We aimed to determine whether circulating MAIT-17 were detectable in children with asthma, and whether they correlated with asthma symptoms or lung function. Children from the SPASM cohort of preschoolers with severe wheeze were reassessed for asthma at school age, and categorized as exacerbators (1 or more severe exacerbations in the previous 12months) or non-exacerbators...
November 28, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/29192573/-a-female-with-expiratory-wheezing-and-inspiratory-stridor
#18
I van der Lee, B J Borgstein
A 42-year-old woman was seen with an inspiratory stridor and expiratory wheezing. The wheezing responded quickly to asthma treatment. The stridor, however, was caused by a significant narrowing of the trachea between the branching of a tracheal bronchus ('bronchus suis' or ' pig bronchus') and the main carina.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29189674/concurrent-community-transmission-of-enterovirus-d68-with-human-rhinoviruses-and-respiratory-syncytial-virus-among-children-in-sendai-japan
#19
Takaya Metoki, Michiko Okamoto, Akira Suzuki, Setsuko Kitaoka, Hiroki Miyabayashi, Yuka Rokugo, Ryoichi Onuma, Suguru Ohmiya, Ko Sato, Hidekazu Nishimura, Hitoshi Oshitani, Satoru Kumaki, Rie Noguchi, Taiki Sato, Yohei Watanabe
BACKGROUND: In the autumn of 2015, we experienced a surge in the number of pediatric cases of wheeze in our hospital, which was suspected to be caused by enterovirus (EV)-D68 transmission in the community. Thus, we implemented an ad hoc retrospective surveillance for EV-D68. METHODS: Patients aged < 15 years old with acute respiratory infection were eligible for inclusion in this study. All enrolled patients underwent virus detection test. Additionally, neutralization tests (NTs) were performed using the stored serum samples of the enrolled patients to compare the antigenicity of the virus isolated in this study with that isolated in 2010 and evaluate the anti-EV-D68 antibody prevalence...
November 17, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29189373/incidental-case-of-relapsing-polychondritis-detected-by-18f-fdg-pet-ct
#20
Hayato Kaida, Kazunari Ishii, Soichiro Hanada, Yuji Tohda, Takamichi Murakami
A 78-year-old man had fever, persistent wheezing, and serum C-reactive protein elevation. Malignant lymphoma was suspected because of mediastinal lymph nodes swelling on CT and soluble interleukin 2 receptor elevation. Symmetric F-FDG uptake in the tracheobronchial tree and bilateral auricles was observed on PET/CT. He was finally diagnosed as having relapsing polychondritis by auricular cartilage biopsy. F-FDG PET/CT may have crucial role in evaluating the extent of inflammation and deciding the biopsy site of relapsing polychondritis...
November 17, 2017: Clinical Nuclear Medicine
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