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https://www.readbyqxmd.com/read/29666655/determinants-of-chronic-respiratory-symptoms-among-pharmaceutical-factory-workers
#1
Sahle Asfaw, Fikre Enquselassie, Yifokire Tefera, Muluken Gizaw, Samson Wakuma, Messay Woldemariam
Background: Chronic respiratory symptoms including chronic cough, chronic phlegm, wheezing, shortness of breath, and chest pain are manifestations of respiratory problems which are mainly evolved as a result of occupational exposures. This study aims to assess determinants of chronic respiratory symptoms among pharmaceutical factory workers. Methods: A case control study was carried out among 453 pharmaceutical factory workers with 151 cases and 302 controls. Data was collected using pretested and structured questionnaire...
2018: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29664908/a-new-model-of-wheezing-severity-in-young-children-using-the-validated-isaac-wheezing-module-a-latent-variable-approach-with-validation-in-independent-cohorts
#2
Steven M Brunwasser, Tebeb Gebretsadik, Diane R Gold, Kedir N Turi, Cosby A Stone, Soma Datta, James E Gern, Tina V Hartert
BACKGROUND: The International Study of Asthma and Allergies in Children (ISAAC) Wheezing Module is commonly used to characterize pediatric asthma in epidemiological studies, including nearly all airway cohorts participating in the Environmental Influences on Child Health Outcomes (ECHO) consortium. However, there is no consensus model for operationalizing wheezing severity with this instrument in explanatory research studies. Severity is typically measured using coarsely-defined categorical variables, reducing power and potentially underestimating etiological associations...
2018: PloS One
https://www.readbyqxmd.com/read/29661500/severity-of-eczema-and-mental-health-problems-in-japanese-schoolchildren-the-tommo-child-health-study
#3
Yasutaka Kuniyoshi, Masahiro Kikuya, Masako Miyashita, Chizuru Yamanaka, Mami Ishikuro, Taku Obara, Hirohito Metoki, Naoki Nakaya, Fuji Nagami, Hiroaki Tomita, Atsushi Hozawa, Ichiro Tsuji, Shigeo Kure, Nobuo Yaegashi, Masayuki Yamamoto, Shinichi Kuriyama
BACKGROUND: The association between eczema and mental health problems in schoolchildren has been underexplored. We aimed to investigate this association with the validated questionnaires. METHODS: Of 46,648 invited children, we analyzed 9954 (21.3%) in the 2nd to the 8th grades from the ToMMo Child Health Study conducted in 2014 and 2015, a cross-sectional survey in Miyagi Prefecture, Japan. We defined eczema status as "normal," "mild/moderate," or "severe," based on the presence of persistent flexural eczema and sleep disturbance, according to the International Study of Asthma and Allergies in Childhood (ISAAC) Eczema Symptom Questionnaire...
April 13, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29658810/early-changes-in-ediary-copd-symptoms-predict-clinically-relevant-treatment-response-at-12-weeks-analysis-from-the-crystal-study
#4
Konstantinos Kostikas, Maryam Aalamian-Mattheis, Veronica Anna Pagano, Xavier Nunez, Robert Fogel, Francesco Patalano, Andreas Clemens
Early detection of treatment response is important in the long-term treatment and management of patients with chronic obstructive pulmonary disease (COPD). This analysis evaluated whether early improvement in symptoms, recorded in the first 7 or 14 days via an electronic diary (eDiary) compared with baseline, can predict clinically meaningful treatment responders at 12 weeks. CRYSTAL was a 12-week, randomized, open-label study that demonstrated the increased effectiveness of indacaterol/glycopyrronium (IND/GLY) or glycopyrronium (GLY), after a direct switch from on-going baseline therapies, in patients with symptomatic COPD and moderate airflow obstruction...
April 16, 2018: COPD
https://www.readbyqxmd.com/read/29658448/-clinical-features-and-prognosis-of-preterm-infants-with-varying-degrees-of-bronchopulmonary-dysplasia
#5
Wen-Li Li, Fa-Lin Xu, Ming Niu, Meng-Di Liu, Hui-Fang Dong
OBJECTIVE: To study the clinical features and prognosis of preterm infants with varying degrees of bronchopulmonary dysplasia (BPD). METHODS: The clinical data of 144 preterm infants with a gestational age of <32 weeks who were admitted to the neonatal intensive care unit from March 2014 to March 2016 and were diagnosed with BPD were collected. According to the severity of BPD, these preterm infants were divided into mild group with 81 infants and moderate/severe group with 63 infants...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29655864/comparison-of-the-severity-of-respiratory-disease-in-children-testing-positive-for-enterovirus-d68-and-human-rhinovirus
#6
Esra Caylan, Ezra Weinblatt, John Welter, Allen Dozor, Guiqing Wang, Sheila M Nolan
OBJECTIVE: To compare the characteristics and severity of respiratory disease in children testing positive for enterovirus D68 (EV-D68) and for human rhinovirus (RhV). STUDY DESIGN: A retrospective single center study of children presenting with acute respiratory symptoms and positive polymerase chain reaction for RhV/EV from September 1, 2014 through October 31, 2014 was performed. Specimens were subsequently tested specifically for EV-D68 and specimens identified as RhV were subtyped when possible into RhV-A, RhV-B, and RhV-C species...
April 11, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29650306/multichannel-lung-sound-analysis-for-asthma-detection
#7
Md Ariful Islam, Irin Bandyopadhyaya, Parthasarathi Bhattacharyya, Goutam Saha
BACKGROUND AND OBJECTIVE: Lung sound signals convey valuable information of the lung status. Auscultation is an effective technique to appreciate the condition of the respiratory system using lung sound signals. The prior works on asthma detection from lung sound signals rely on the presence of wheeze. In this paper, we have classified normal and asthmatic subjects using advanced signal processing of posterior lung sound signals, even in the absence of wheeze. METHODS: We collected lung sounds of 60 subjects (30 normal and 30 asthma) using a novel 4-channel data acquisition system from four different positions over the posterior chest, as suggested by the pulmonologist...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29643544/-bronchial-adenoid-cystic-carcinoma-masquerading-as-bronchial-asthma-a-case-report
#8
M Lu, M Wang, X Zhu, Y H Chen, W Z Yao
Here we reported a case of bronchial adenoid cystic carcinoma from Peking University Third Hospital. A 40-year-old female presented with dry cough for 1 year and nocturnal paroxysmal attacks of wheezing for 4 months. She was a non-smoker, and did not have past histories of asthma or allergy. On physical examination, no stridor, wheezing and cyanosis were present and the general appearance was good. The results of the laboratory analysis, including blood eosinophils count, immunoglobulin E level and chest X-ray were normal...
April 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29629404/marijuana-use-associations-with-pulmonary-symptoms-and-function-in-tobacco-smokers-enrolled-in-the-subpopulations-and-intermediate-outcome-measures-in-copd-study-spiromics
#9
Madeline A Morris, Sean R Jacobson, Gregory L Kinney, Donald P Tashkin, Prescott G Woodruff, Eric A Hoffman, Richard E Kanner, Christopher B Cooper, M Brad Drummond, R Graham Barr, Elizabeth C Oelsner, Barry J Make, MeiLan K Han, Nadia N Hansel, Wanda K O'Neal, Russell P Bowler
Background: Marijuana is often smoked via a filterless cigarette and contains similar chemical makeup as smoked tobacco. There are few publications describing usage patterns and respiratory risks in older adults or in those with chronic obstructive pulmonary disease (COPD). Methods: A cross-sectional analysis of current and former tobacco smokers from the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) study assessed associations between marijuana use and pulmonary outcomes. Marijuana use was defined as never, former (use over 30 days ago), or current (use within 30 days)...
January 24, 2018: Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation
https://www.readbyqxmd.com/read/29628597/anesthetic-management-in-pediatric-patient-for-percutaneous-endoscopic-gastrostomy-with-mitochondrial-myopathy-leigh-syndrome
#10
Ebru Tarikçi Kiliç, Nelgin Gerenli, Mehmet Salim Akdemir, Necmi Onur Tastan, Egemen Atag
Leigh syndrome (LS) is a rare disease mainly affecting the central nervous system due to the abnormalities of mitochondrial energy generation and seen in early childhood with progressive loss of movement, mental abilities, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Anesthesia and surgery exacerbate the risks of aspiration, wheezing, and breathing difficulties. Tracheal irritability can be stimulated with the efforts of intubation. We report the anesthetic management of a rare case of an 11-year-old boy with a severe form of LS for percutaneous endoscopic gastrostomy insertion...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29628377/lung-function-trajectories-from-pre-school-age-to-adulthood-and-their-associations-with-early-life-factors-a-retrospective-analysis-of-three-population-based-birth-cohort-studies
#11
Danielle C M Belgrave, Raquel Granell, Steve W Turner, John A Curtin, Iain E Buchan, Peter N Le Souëf, Angela Simpson, A John Henderson, Adnan Custovic
BACKGROUND: Maximal lung function in early adulthood is an important determinant of mortality and COPD. We investigated whether distinct trajectories of lung function are present during childhood and whether these extend to adulthood and infancy. METHODS: To ascertain trajectories of FEV1 , we studied two population-based birth cohorts (MAAS and ALSPAC) with repeat spirometry from childhood into early adulthood (1046 participants from 5-16 years and 1390 participants from 8-24 years)...
April 5, 2018: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29628073/wheezing-in-infants-a-pandemic-condition-that-need-to-be-treated-with-patience
#12
EDITORIAL
L Garcia-Marcos
No abstract text is available yet for this article.
May 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29627188/maternal-black-race-and-persistent-wheezing-illness-in-former-extremely-low-gestational-age-newborns-secondary-analysis-of-a-randomized-trial
#13
Katherine C Wai, Anna M Hibbs, Martina A Steurer, Dennis M Black, Jeanette M Asselin, Eric C Eichenwald, Philip L Ballard, Roberta A Ballard, Roberta L Keller
OBJECTIVE: To evaluate the relationship between maternal self-reported race/ethnicity and persistent wheezing illness in former high-risk, extremely low gestational age newborns, and to quantify the contribution of socioeconomic, environmental, and biological factors on this relationship. STUDY DESIGN: We assessed persistent wheezing illness determined at 18-24 months corrected (for prematurity) age in survivors of a randomized trial. Parents/caregivers were surveyed for wheeze and inhaled asthma medication use quarterly to 12 months, and at 18 and 24 months...
April 4, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29626974/a-young-man-with-hemoptysis-and-cavitary-lung-lesions
#14
Virginia A Brady, Andrey V Zinchuk, Mark D Siegel, Jennifer D Possick
A man in his 20s presented with 2 months of mild fatigue and intermittent hemoptysis of less than a tablespoon per episode. He was previously healthy and was on no medications. He denied fevers, night sweats, weight loss, wheezing, dyspnea, musculoskeletal symptoms, and rashes. He had emigrated from a South American country to the United States 3 years earlier. He worked as a groundskeeper but had no exposures to animals, mold, or dusts. He reported rare prior cigarette smoking with no history of alcohol or drug use...
April 2018: Chest
https://www.readbyqxmd.com/read/29624458/burden-of-asthma-among-patients-adherent-to-ics-laba-a-real-world-study
#15
Jill Davis, Frank Trudo, James Siddall, Mark Small
OBJECTIVES: Asthma is a chronic respiratory condition with a U.S. prevalence of 7.4%. Despite numerous treatment options, asthma remains poorly controlled in some patients. Uncontrolled asthma is associated with high healthcare resource utilization (HCRU) and reduced productivity. This study assessed symptoms, productivity, and HCRU of patients adherent to medium/high-dosage inhaled corticosteroid/long-acting beta2-agonist (ICS/LABA) treatment, and the relationship of asthma control with these parameters...
April 6, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29622672/viral-infections-in-wheezing-disorders
#16
REVIEW
Peter Le Souëf
Over the past year, studies into virus-induced wheeze in children have shifted towards investigations that examine the mechanisms by which respiratory viruses cause wheeze and an increase in studies examining the effects of novel interventions to reduce wheezing exacerbations. Studies on rhinovirus species (RV)-C infection have found that this is associated with a decrease in expression of CDHR3, the cellular receptor specific for this virus, and a decrease in interferon-β expression, both of which are likely to favour RV-C infection...
March 31, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29621411/the-southern-sweden-adolescent-allergy-cohort-prevalence-of-allergic-diseases-and-cross-sectional-associations-with-individual-and-social-factors
#17
Therese Sterner, Ada Uldahl, Åke Svensson, Jonas Björk, Cecilia Svedman, Christel Nielsen, Alf Tunsäter, Magnus Bruze, Hampus Kiotseridis
OBJECTIVES: Asthma and allergic diseases are the most frequent chronic diseases in childhood worldwide, and considered a burden for the affected children and their families. The diseases impose an economic burden on society if not diagnosed and treated properly and management of and these diseases are challenging for healthcare professionals. The aim of the present investigation was to assess the prevalence of allergic diseases in an unselected cohort of adolescents in southern Sweden...
April 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29618481/is-there-a-role-for-montelukast-in-the-management-of-viral-induced-wheeze-in-preschool-children
#18
Alisha Burman
No abstract text is available yet for this article.
April 4, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29617923/breastfeeding-and-childhood-wheeze-age-specific-analyses-and-longitudinal-wheezing-phenotypes-as-complimentary-approaches-to-the-analysis-of-cohort-data
#19
Maria A Quigley, Claire Carson, Yvonne Kelly
Systematic reviews suggest that breastfeeding is associated with a lower risk of asthma, although marked heterogeneity exists. Using UK Millennium Cohort Study data (n = 10,126 children born 2000-2001), we examined the association between breastfeeding duration and wheezing in the past year, first at each age-group separately (age 9 months, 3, 5, 7 and 11 years) and then as a longitudinal wheezing phenotype: 'early transient' (wheezing any time up to age 5 but not thereafter); 'late onset' (any time from age 7 but not beforehand); 'persistent' (any time up to age 5 and any time from age 7)...
April 3, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29617476/acute-lower-respiratory-infection-in-guarani-indigenous-children-brazil
#20
Patricia Gomes de Souza, Andrey Moreira Cardoso, Clemax Couto Sant'Anna, Maria de Fátima Bazhuni Pombo March
OBJECTIVE: To describe the clinical profile and treatment of Brazilian Guarani indigenous children aged less than five years hospitalized for acute lower respiratory infection (ALRI), living in villages in the states from Rio de Janeiro to Rio Grande do Sul. METHODS: Of the 234 children, 23 were excluded (incomplete data). The analysis was conducted in 211 children. Data were extracted from charts by a form. Based on record of wheezing and x-ray findings, ALRI was classified as bacterial, viral and viral-bacterial...
March 29, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
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