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Calgary depression scale schizophrenia

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https://www.readbyqxmd.com/read/30098383/in-schizophrenia-serum-level-of-neurotrophin-3-nt-3-is-increased-only-if-depressive-symptoms-are-present
#1
Jaśmina Arabska, Anna Łucka, Dominik Strzelecki, Adam Wysokiński
AIM: Neurotrophin-3 (NT-3) is a neurotrophic factor responsible for promoting development, survival and function of neurons. NT-3 may be involved in the etiopathology of schizophrenia and mood disorders. However it must be cleared up if changes of NT-3 level are associated with schizophrenia itself or are secondary to certain symptoms (e.g. negative or depressive). The aim of this study was to examine whether the presence of negative or depressive symptoms affects peripheral NT-3 concentration in patients with schizophrenia...
August 8, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/30081208/consequences-of-persistent-depression-and-apathy-in-first-episode-psychosis-a-one-year-follow-up-study
#2
Siv Hege Lyngstad, Erlend Strand Gardsjord, Carmen Simonsen, Magnus Johan Engen, Kristin Lie Romm, Ingrid Melle, Ann Færden
BACKGROUND: Apathy and depression are prevalent in first-episode psychosis (FEP), have overlapping clinical features and are linked to social dysfunction, with indications that persisting symptoms have an even more negative impact. Our objective was to investigate the prevalence of persisting depression (PD), persisting apathy (PA), to what extent they overlap and their relative associations to functioning during a one-year follow-up. METHODS: One hundred and twenty-five participants with a FEP were recruited, and 88 (70%) were reassessed at follow-up...
July 29, 2018: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/30078128/hypovitaminosis-d-is-associated-with-negative-symptoms-suicide-risk-agoraphobia-impaired-functional-remission-and-antidepressant-consumption-in-schizophrenia
#3
G Fond, M Faugere, C Faget-Agius, M Cermolacce, R Richieri, L Boyer, C Lançon
Hypovitaminosis D has been associated with, respectively, major depressive disorder, schizophrenia (SZ), and cognitive disorders in the general population, and with positive and negative symptoms and metabolic syndrome in schizophrenia. The objective was to determine the prevalence of hypovitaminosis D and associated factors in a non-selected multicentric sample of SZ subjects in day hospital. Hypovitaminosis D was defined by blood vitamin D level < 25 nM. Depressive symptoms were assessed by the Calgary Depression Rating Scale Score and Positive and Negative Syndrome Scale Score...
August 4, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/30040794/-psychopathological-features-of-affective-disorders-in-schizotypal-disorder
#4
N N Ivanets, E N Efremova
AIM: To explore psychopathological features of affective disorders in the structure of schizotypal disorder. MATERIAL AND METHODS: The study included 102 patients with schizotypal disorder, aged from 18 to 60 years. Assessment was done using clinical/ psychopathological method and psychometric scales - Calgary depression scale in patients with schizophrenia (CDSS), General Clinical Impression scale (CGI), Yang's mania scale (YMRS). RESULTS AND CONCLUSION: Affective disorders are noted in the majority of inpatients with schizotypal disorder...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/30007120/toward-a-transdiagnostic-tool-to-evaluate-depressive-symptoms-across-mental-disorders-validation-of-the-calgary-depression-rating-scale-in-patients-with-major-depressive-disorder
#5
Jean-Arthur Micoulaud-Franchi, Mélanie Faugere, Sebastien Weibel, Catherine Faget, Christophe Lancon, Raphaëlle Richieri, Michel Cermolacce
The severity of depressive symptoms across two discrete mental disorders should be evaluated with the same psychometrically validated tools. In patients with schizophrenia the Calgary Depression Rating Scale (CDSS) is recommended for evaluating depressive symptoms. The aim of this study was to validate the CDSS in patients with major depressive disorder. The CDSS exhibit satisfactory psychometric properties for evaluating depressive symptoms in major depressive disorder. Clinicians and researchers now have a validated scale at their disposal to evaluate depressive symptoms in various mental disorders using a transdiagnostic approach...
July 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29942132/structural-equation-modeling-approach-between-salience-network-dysfunction-depressed-mood-and-subjective-quality-of-life-in-schizophrenia-an-ica-resting-state-fmri-study
#6
Masashi Ohta, Masahito Nakataki, Tomoya Takeda, Shusuke Numata, Takeo Tominaga, Naomi Kameoka, Hiroko Kubo, Makoto Kinoshita, Kanae Matsuura, Maki Otomo, Naoya Takeichi, Masafumi Harada, Tetsuro Ohmori
Purpose: Quality of life (QOL) is an important clinical outcome for patients with schizophrenia, and recent studies have focused on subjective QOL. We evaluated the causal relationship between psychosocial aspect of subjective QOL, symptoms, cognitive functions, and salience network (SN) dysfunction in schizophrenia using structural equation modeling (SEM). Patients and methods: We performed a cross-sectional study of 21 patients with symptomatically stabilized schizophrenia and 21 age-, sex-, and education level-matched healthy controls who underwent resting-state functional magnetic resonance imaging...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29890508/trajectories-of-depressive-symptoms-in-the-acute-phase-of-psychosis-implications-for-treatment
#7
E Kjelby, R Gjestad, I Sinkeviciute, R A Kroken, E-M Løberg, H A Jørgensen, E Johnsen
Depression is common in schizophrenia and associated with negative outcomes. Previous studies have identified heterogeneity in treatment response in schizophrenia. We aimed to investigate different trajectories of depression in patients suffering from psychosis and predictors of change in depressive symptoms during antipsychotic treatment. Two hundred and twenty-six patients >18 years acutely admitted due to psychosis were consecutively included and the follow-up was 27 weeks. The Calgary Depression Scale for Schizophrenia (CDSS) sum score was the primary outcome...
August 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29804925/factor-structure-of-the-positive-and-negative-syndrome-scale-panss-in-people-at-ultra-high-risk-uhr-for-psychosis
#8
Zixu Yang, Keane Lim, Max Lam, Richard Keefe, Jimmy Lee
INTRODUCTION: The Positive and Negative Syndrome Scale (PANSS), a comprehensive psychopathology assessment scale used in the evaluation of psychopathology in schizophrenia, is also often used in the Ultra-High-Risk (UHR) population. This paper examined the dimensional structure of the PANSS in a UHR sample. METHODS: A total of 168 individuals assessed to be at UHR for psychosis on the Comprehensive Assessment of At-Risk Mental States (CAARMS) were evaluated on the PANSS, Calgary Depression Scale for Schizophrenia (CDSS), Beck Anxiety Inventory (BAI), Brief Assessment of Cognition in Schizophrenia (BACS), and Global Assessment of Functioning (GAF)...
May 24, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29730871/the-relationship-of-insight-with-psychopathology-and-neuropsychological-functioning-in-patients-with-schizophrenia
#9
Ahmet Tiryaki, Aykut Karahan, Filiz Civil Arslan
OBJECTIVE: The aim of this study was to investigate the relationship of the different dimensions of insight with clinical variables, symptom severity, and cognitive functions in patients with schizophrenia. METHOD: In this cross-sectional descriptive study,  66  out  patients that applied to the Karadeniz Technical University, Psychiatry Clinic and were diagnosed with schizophrenia according to DSM-IV were evaluated. The patients were evaluated with Structured Clinical Interview for DSM (SCID-I), the Positive and Negative Syndrome Scale (PANSS), the Calgary Depression Scale for Schizophrenia (CDSS), and the Schedule for Assessing the Three Components of Insight (SAI)...
2018: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/29721726/association-between-serum-lipid-levels-osteoprotegerin-and-depressive-symptomatology-in-psychotic-disorders
#10
Sherif M Gohar, Ingrid Dieset, Nils Eiel Steen, Ragni H Mørch, Trude S Iversen, Vidar M Steen, Ole A Andreassen, Ingrid Melle
Although the relationship between positive and negative symptoms of psychosis and dyslipidemia has been thoroughly investigated in recent studies, the potential link between depression and lipid status is still under-investigated. We here examined the association between lipid levels and depressive symptomatology in patients with psychotic disorders, in addition to their possible inflammatory associations. Participants (n = 652) with the following distribution: schizophrenia, schizophreniform and schizoaffective disorder (schizophrenia group, n = 344); bipolar I, II, NOS, and psychosis NOS (non-schizophrenia group, n = 308) were recruited consecutively from the Norwegian Thematically Organized Psychosis (TOP) Study...
May 2, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29677621/depressive-symptoms-in-chinese-male-inpatients-with-schizophrenia-prevalence-and-clinical-correlates
#11
Yan-Min Xu, Fu Li, Xiao-Bo Liu, Bao-Liang Zhong
Depression is common in patients with schizophrenia and associated with serious consequences. However, previous studies have mixed findings on characteristics of depression in schizophrenia, partly because of the use of depressive symptom scales that are not specific to schizophrenia. This study examined the prevalence and correlates of depressive symptoms in Chinese patients with schizophrenia. A consecutive sample of 349 male inpatients with schizophrenia was recruited from the largest psychiatric specialty hospital in south-central China...
June 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29584866/levels-of-serum-brain-derived-neurotropic-factor-in-individuals-at-ultra-high-risk-for-psychosis-findings-from-the-longitudinal-youth-at-risk-study-lyriks
#12
Jie Yin Yee, Tih-Shih Lee, Jimmy Lee
Background: Identifying biomarkers to enrich prognostication and risk predictions in individuals at high risk of developing psychosis will enable stratified early intervention efforts. Brain-derived neurotrophic factor (BDNF) has been widely studied in schizophrenia and in first-episode psychosis with promising results. The aim of this study was to examine the levels of serum BDNF between healthy controls and individuals with ultra-high risk of psychosis (UHR). Methods: A sample of 106 healthy controls and 105 UHR individuals from the Longitudinal Youth at Risk Study was included in this study...
March 23, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29503230/effects-of-a-lifestyle-intervention-on-psychosocial-well-being-of-severe-mentally-ill-residential-patients-elips-a-cluster-randomized-controlled-pragmatic-trial
#13
Annemarie P M Stiekema, Anne Looijmans, Lisette van der Meer, Richard Bruggeman, Robert A Schoevers, Eva Corpeleijn, Frederike Jörg
Large studies investigating the psychosocial effects of lifestyle interventions in patients with a severe mental illness (SMI) are scarce, especially in residential patients. This large, randomized controlled, multicentre pragmatic trial assessed the psychosocial effects of a combined diet-and-exercise lifestyle intervention targeting the obesogenic environment of SMI residential patients. Twenty-nine sheltered and clinical care teams were randomized into intervention (n=15) or control (n=14) arm. Team tailored diet-and-exercise lifestyle plans were set up to change the obesogenic environment into a healthier setting, and team members were trained in supporting patients to make healthier choices...
March 1, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29421173/effects-of-chlorpromazine-on-sleep-quality-clinical-and-emotional-measures-among-patients-with-schizophrenia
#14
Qingli Meng, Rongqin Li, Feng Hou, Qiulan Zhang
OBJECTIVES: The present study was aimed to examine the effects of chlorpromazine on sleep quality, clinical and emotional measures in people suffering from schizophrenia. PATIENTS AND METHODS: Twenty-five patients with schizophrenia or schizoaffective disorder were enrolled in this study. Our study included a one-week running-in no-treatment period and two-month experimental period. Patients received chlorpromazine during the experimental period. The baseline and treatment outcome were recorded...
February 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29417623/serum-levels-of-interleukin-6-in-schizophrenic-patients-during-treatment-augmentation-with-sarcosine-results-of-the-pulsar-study
#15
Dominik Strzelecki, Małgorzata Urban-Kowalczyk, Adam Wysokiński
OBJECTIVE: Augmentation of sarcosine, a natural inhibitor of the glycine transporter type I, normalizes glutamatergic neurotransmission, having beneficial impact on primary negative symptoms in schizophrenia and may also influence immune system and interleukin 6 (IL-6) levels. AIM: Finding a relationship between initial IL-6 serum concentrations or its changes and severity of symptoms as a result of sarcosine addition to stable antipsychotic treatment. METHOD: Fifity-eight individuals with schizophrenia with predominantly negative symptoms completed a 6-month randomized, double-blind placebo-controlled prospective study...
March 2018: Human Psychopharmacology
https://www.readbyqxmd.com/read/29334657/relationship-of-obsessive-compulsive-symptoms-to-clinical-variables-and-cognitive-functions-in-individuals-at-ultra-high-risk-for-psychosis
#16
Ahmet Zihni Soyata, Selin Akışık, Damla İnhanlı, Handan Noyan, Alp Üçok
Few studies have investigated the relationship between obsessive-compulsive symptoms (OCS) and clinical variables, and cognition in individuals at ultra high-risk (UHR) for psychosis. The aim of this study was to evaluate the frequency of OCS and their relationship with clinical variables and cognitive functions in individuals at UHR. Eighty-four individuals at UHR for psychosis were administered the Brief Psychiatric Rating Scale, the Yale-Brown Obsession Compulsion Symptom Check List and, the Calgary Depression Scale for Schizophrenia...
March 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29224023/negative-symptoms-and-avoidance-of-social-interaction-a-study-of-non-verbal-behaviour
#17
RANDOMIZED CONTROLLED TRIAL
Elizabeth Worswick, Sara Dimic, Christiane Wildgrube, Stefan Priebe
BACKGROUND: Non-verbal behaviour is fundamental to social interaction. Patients with schizophrenia display an expressivity deficit of non-verbal behaviour, exhibiting behaviour that differs from both healthy subjects and patients with different psychiatric diagnoses. The present study aimed to explore the association between non-verbal behaviour and symptom domains, overcoming methodological shortcomings of previous studies. SAMPLING AND METHODS: Standardised interviews with 63 outpatients diagnosed with schizophrenia were videotaped...
2018: Psychopathology
https://www.readbyqxmd.com/read/29220783/a-study-to-compare-the-differences-between-genders-in-psychiatric-comorbidities-in-individuals-with-psychoses
#18
Praveen Das, Priya Sreedaran, Ashok Mv
BACKGROUND: Psychiatric comorbidities worsen the outcome and increase severity of suffering in psychotic disorders. Gender differences have also been found to impact the severity and outcome in psychoses. In this background, this study attempted to compare psychiatric comorbidity between genders. AIMS AND OBJECTIVES: The aim was to compare psychiatric co-morbidity between men and women with psychotic disorders. METHODOLOGY: A descriptive cross sectional study design was used...
February 2018: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29197359/cultural-adaptation-and-validity-of-the-malay-version-of-the-brief-psychiatric-rating-scale-bprs-m-among-patients-with-schizophrenia-in-a-psychiatric-clinic
#19
Anne Yee, Boon Seng Ng, Helenna Maria Hisham Hashim, Mahmoud Danaee, Huai Heng Loh
BACKGROUND: This study evaluates the psychometric properties of the Malay version of the Brief Psychiatric Rating Scale (BPRS-M) among patients with schizophrenia in a psychiatric outpatient clinic. METHODS: Ninety-nine schizophrenia outpatients were administered the Malay version of the Brief Psychiatric Rating Scale (BPRS-M), Malay version of Positive and Negative Syndrome Scale (PANSS), Malay version of Calgary Depression Scale for Schizophrenia (CDSS) and Malay version of World Health Organization Quality of Life - Brief Version (WHOQOL-BREF)...
December 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29195803/-validation-of-the-french-version-of-the-self-evaluation-of-negative-symptoms-sns
#20
C Hervochon, V Bourgeois, M Rotharmel, J-B Duboc, B Le Goff, P Quesada, D Campion, S Dollfus, O Guillin
INTRODUCTION: Schizophrenia is a disorder affecting 1% of the population and is associated with severe functional impairment. Negative symptoms are responsible for the majority of this impairment, and many patients with schizophrenia have negative symptoms. However, their evaluation is still a challenge. Thus, standardized assessments are needed to facilitate identification of these symptoms. Many tools have been developed, but most are based on observer ratings. Self-evaluation can provide an additional outcome measure and allow patients to be more engaged in their treatment...
November 28, 2017: L'Encéphale
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