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Induction labor

Lu-Yao Wang, Wang-Sheng Wang, Ya-Wei Wang, Jiang-Wen Lu, Yi Lu, Chu-Yue Zhang, Wen-Jiao Li, Kang Sun, Hao Ying
Preterm premature rupture of fetal membranes precedes 30-40% of preterm births. Activation of matrix metalloproteases (MMPs) is the one of the major causes of extracellular matrix (ECM) degradation in membrane rupture. Increased cortisol, regenerated by 11β-hydroxysteroid dehydrogenase 1 in the amnion at parturition, is known to participate in a number of parturition-pertinent events. However, whether cortisol has a role in the regulation of MMPs in the membranes is not known. Here, we addressed this issue using human amnion tissue, the most tensile layer of the membranes...
October 10, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Eva Rydahl, Lena Eriksen, Mette Juhl
OBJECTIVE: The objective of this review was to identify, assess and synthesize the best available evidence on the effects of induction prior to post-term on the mother and fetus. Maternal and fetal outcomes after routine labor induction in low-risk pregnancies at 41+0 to 41+6 gestational weeks (prior to post-term) were compared to routine labor induction at 42+0 to 42+6 gestational weeks (post-term). INTRODUCTION: Induction of labor when a pregnancy exceeds 14 days past the estimated due date has long been used as an intervention to prevent adverse fetal and maternal outcomes...
October 5, 2018: JBI Database of Systematic Reviews and Implementation Reports
Alexandros Sotiradis, Stamatios Petousis, Basky Thilaganathan, Francesc Figueras, Wellington P Martins, Anthony O Odibo, Konstantinos Dinas, Jon Hyett
OBJECTIVE: The rate of maternal and perinatal complications increases after 39 weeks in both unselected and complicated pregnancies. The aim of this study was to synthesize quantitatively the evidence on the effect of elective induction of labor at term on the risk of Cesarean section, and maternal and perinatal outcome. METHODS: We searched PubMed, US Registry of Clinical Trials, SCOPUS and CENTRAL databases from inception to August 2018. We additionally searched the references of retrieved articles...
October 8, 2018: Ultrasound in Obstetrics & Gynecology
Z L Bao, J Zhang
Objective: To summarize and analyze the methods of termination of pregnancy in the first and second trimester of pregnancy with severe cardiovascular disease. Methods: A retrospective analysis of 27 cases of termination of pregnancy in the first and second trimester of pregnancy in Beijing Anzhen Hospital from January 1, 2016 to December 30, 2017. All of these pregnant women were pregnancy complicated with severe cardiovascular disease in grade Ⅴ pregnancy risk. Results: (1) The age of 27 pregnant women was 22-40 years, gestational age was 6-27 weeks; cardiac function grade before induced labor was: 5 cases of grade Ⅱ, 15 cases of grade Ⅲ, 7 cases of grade Ⅳ...
September 25, 2018: Zhonghua Fu Chan Ke za Zhi
Federico Migliorelli, Núria Baños, Martina Aida Angeles, Claudia Rueda, Laura Salazar, Eduard Gratacós, Montse Palacio
OBJECTIVE: To develop a model combining clinical and sonographic features to predict the risk of cesarean delivery after the induction of labor (IOL). METHODS: We designed a prospective observational study involving women admitted for IOL. The main outcome was defined as cesarean delivery due to failed IOL or arrest of labor. Several clinical and ultrasonographic variables were collected. Seventy percent of the sample was used to build the predictive model, using stepwise logistic regression, while the remaining sample was used for validation...
October 5, 2018: Fetal Diagnosis and Therapy
Kondou Aya, Haku Mari
The aim of this study was to clarify the experiences of husbands present at their wives' emergency cesarean sections. Semi-structured interviews were conducted for nine husbands who attended their wives' emergency cesarean sections. The results were analyzed using a qualitative inductive approach. Several categories such as [wife's labor pain will be unbearable if I look], [situation was beyond one's control], and [sense of relief experienced by midwife care] were extracted from the husbands' experiences the need for an emergency cesarean section was established...
2018: Journal of Medical Investigation: JMI
F M Wærsted, K A Jensen, E Reinoso-Maset, L Skipperud
A method was developed for direct measurements of 226 Ra in water samples with triple quadrupole inductively coupled plasma mass spectrometry (ICP-QQQ). The limit of detection was 0.42 pg L-1 226 Ra (15 mBq L-1 , 0.42 pCi L-1 ), which is compliant with the specifications for methods used for routine analysis of drinking water quality according to European and U.S. regulations. The use of N2 O as reaction gas ensured that no separation before analysis was necessary. Water samples with high total dissolved solids (conductivity >100 mS cm-1 ) were also successfully analyzed after a simple dilution, yet the associated detection limit was higher (17 pg L-1 , 0...
October 3, 2018: Analytical Chemistry
Jodie G Katon, Erica W Ma, George Sayre, Laurie C Zephyrin, Kristina M Cordasco, Elizabeth M Yano, John C Fortney
INTRODUCTION: Little is known about women veterans' experiences accessing and using Department of Veterans Affairs (VA) maternity care, which is nearly all purchased from non-VA providers. OBJECTIVE: To understand women veterans' experiences, preferences, and challenges using VA maternity care. METHODS: We conducted 27 semistructured interviews with women veterans who used VA maternity care during fiscal year 2016. To capture a wide variety of experiences, we randomly sampled veterans from urban and rural VA facilities with higher and lower volumes of VA paid deliveries...
September 29, 2018: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
Elizabeth M Coviello, Sara N Iqbal, Katherine L Grantz, Chun-Chih Huang, Helain J Landy, Uma M Reddy
BACKGROUND: The optimal route of delivery in early onset preeclampsia before 34 weeks is debated, as many clinicians are reluctant to proceed with induction for perceived high risk of failure. OBJECTIVE: Our objective was to investigate labor induction success rates and compare maternal and neonatal outcomes, by intended mode of delivery in women with early preterm preeclampsia. METHODS: We identified 914 singleton pregnancies with preeclampsia in the Consortium on Safe Labor study for analysis who delivered between 24 0/7 and 33 6/7 weeks...
September 28, 2018: American Journal of Obstetrics and Gynecology
Dana Vitner, Inna Bleicher, Einav Kadour-Peero, Liron Borenstein-Levin, Amir, Kugelman, Shlomi Sagi, Ron Gonen
BACKGROUND: The macrosomic fetus predisposes a variety of adverse maternal and perinatal outcomes. Although older studies have shown no benefit in inducing women of suspected macrosomic fetuses, more updated studies show different information. OBJECTIVES: The aim of our study was to compare induction of labor versus expectant management among women with macrosomic neonates weighing more than 4000 g at term (between 370/7 and 416/7 weeks' gestation). STUDY DESIGN: This was a retrospective cohort study of all live-born singleton pregnancies with macrosomic newborns who were delivered at our institution between 1 January, 2000 and 1 June, 2015...
October 1, 2018: Journal of Maternal-fetal & Neonatal Medicine
Olof Stephansson, Kari Johansson, Jonas Söderling, Ingmar Näslund, Martin Neovius
BACKGROUND: Obesity increases the risk of adverse delivery outcomes. Whether weight loss induced by bariatric surgery influences these risks remains to be determined. The objective was to investigate the risk of adverse delivery outcomes among post-surgery women compared with women without bariatric surgery history but with similar characteristics. METHODS AND FINDINGS: We identified 801,443 singleton live-born term births (≥37 gestational weeks) in the Swedish Medical Birth Register between 1 January 2006 and 31 December 2013, of which 1,929 were in women with a history of bariatric surgery and a pre-surgery weight available from the Scandinavian Obesity Surgery Registry...
September 2018: PLoS Medicine
Hyun Joo Shin, Sa Ra Lee, A-Mi Roh, Young-Mee Lim, Kyung Ah Jeong, Hye-Sung Moon, Hye Won Chung
Misoprostol is widely used in daily practice for induction of labor and cervical dilatation prior to intrauterine procedures, including dilatation and curettage or hysteroscopy. Anaphylactic shock to intravaginal misoprostol can occur not only in pregnant women, as reported in 2 previous cases, but also in a non-pregnant, perimenopausal woman, as in the case described herein. A 49-year-old woman received vaginal misoprostol for cervical ripening prior to hysteroscopic myomectomy and experienced anaphylactic shock...
September 2018: Obstetrics & Gynecology Science
Moti Tolera, Alula M Teklu, Abdurahman Ahmed, Abdiwahab Hashi, Lemessa Oljira, Zerihun Abebe, Wondimagegn Gezahegn, Kahasse Gebre Kidan
BACKGROUND: Maternal mortality is a critical indicator in assessing the quality of services provided by a health care system. Approximately 99% of all maternal deaths occur in developing countries; where a majority of the causes of these deaths are preventable. CASE PRESENTATION: A 25-year-old, married, multigravida, black woman who has had six live births presented to a health center with the chief compliant of abnormal body swelling of 2 days' duration and loss of consciousness...
September 26, 2018: Journal of Medical Case Reports
Ahmet Eser, Enis Ozkaya
BACKGROUND: A wide uterocervical angle >95° detected during the second trimester was associated with an increased risk for spontaneous preterm birth. OBJECTIVE: We aimed to determine whether an ultrasonographic marker, uterocervical angle, correlates with satisfactory response to labor induction. STUDY DESIGN: We conducted a prospective cohort study from May 2016 through December 2017 of singleton term gestations undergoing transvaginal ultrasound for cervical length screening and uterocervical angle measurement...
September 25, 2018: Journal of Maternal-fetal & Neonatal Medicine
Cecilia Villalain, Ignacio Herraiz, María Soledad Quezada, Paula Gómez Arriaga, Elisa Simón, Enery Gómez-Montes, Alberto Galindo
OBJECTIVE: To compare vaginal delivery rate and perinatal outcomes of fetuses with late-onset fetal growth restriction (FGR) undergoing labor induction, depending on the method for cervical ripening (dinoprostone vs. Foley balloon). MATERIAL AND METHODS: We conducted a retrospective cohort study of 148 consecutive singleton gestations diagnosed with stage I late-onset FGR and Bishop score < 7, in which labor induction was indicated at ≥37 + 0 weeks. Before January 2016, cervical ripening was achieved with 10 mg of vaginal dinoprostone (n = 77) and afterwards with Fo-ley balloon (n = 71)...
September 24, 2018: Fetal Diagnosis and Therapy
Cynthia Abraham
No abstract text is available yet for this article.
October 2018: Obstetrics and Gynecology
Jennifer Akuamoah-Boateng, Rachael Spencer
No abstract text is available yet for this article.
September 5, 2018: Midwifery
James A Sargent, Leah M Savitsky, Mekhala V Dissanayake, Jamie O Lo, Yvonne W Cheng, Aaron B Caughey
OBJECTIVE:  We sought to identify factors associated with a successful trial of labor (TOL) following two cesarean deliveries (CDs) in a contemporary North American cohort. STUDY DESIGN:  This is a retrospective cohort study of term, nonanomalous, singleton, vertex pregnancies attempting a vaginal birth after cesarean (VBAC) following a history of two previous CDs in the United States from 2012 to 2014. Maternal and intrapartum factors were analyzed using chi-square tests and multivariable logistic regression...
September 19, 2018: American Journal of Perinatology
Percy Pacora, Roberto Romero, Sunil Jaiman, Offer Erez, Gaurav Bhatti, Bogdan Panaitescu, Neta Benshalom-Tirosh, Eun Jung Jung, Chaur-Dong Hsu, Sonia S Hassan, Lami Yeo, Nicholas Kadar
Objectives To investigate mechanisms of in utero death in normally formed fetuses by measuring amniotic fluid (AF) biomarkers for hypoxia (erythropoietin [EPO]), myocardial damage (cardiac troponin I [cTnI]) and brain injury (glial fibrillary acidic protein [GFAP]), correlated with risk factors for fetal death and placental histopathology. Methods This retrospective, observational cohort study included intrauterine deaths with transabdominal amniocentesis prior to induction of labor. Women with a normal pregnancy and an indicated amniocentesis at term were randomly selected as controls...
September 19, 2018: Journal of Perinatal Medicine
Kristjana Einarsdóttir, Hjördís Ýr Bogadóttir, Ragnheiður Ingibjörg Bjarnadóttir, Þóra Steingrímsdóttir
INTRODUCTION: Obstetric interventions appear to increase with advancing maternal age, but limited supporting evidence exists, particularly for young women and specifically for prelabor and intrapartum cesarean birth. The aim of this study was to explore the association between obstetric interventions and maternal age in a low-risk population. METHODS: The study was restricted to all low-risk, nulliparous women with singleton, vertex, term births who gave birth in Iceland from 1997 to 2015, identified in the Icelandic Medical Birth Registry...
September 19, 2018: Journal of Midwifery & Women's Health
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