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Thomas Obinchemti Egbe, Therese Gaelle Badjang, Robert Tchounzou, Eta-Nkongho Egbe, Marcelin Ngowe Ngowe
OBJECTIVES: Uterine fibroids are common among the black race and associated with adverse outcomes in pregnancy. The aim of this study was to determine the prevalence, clinical presentation and maternal and foetal outcomes of birth among pregnant women with leiomyoma in two secondary care hospitals in Limbe and Buea, Cameroon. RESULTS: The prevalence of fibroid in pregnancy was 16.7%. Respondents with leiomyoma were older than those without (p < 0.001) and of low parity (p = 0...
December 13, 2018: BMC Research Notes
Joyce Wamoyi, Ana Maria Buller, Daniel Nyato, Nambusi Kyegombe, Rebecca Meiksin, Lori Heise
BACKGROUND: Age-disparate sex is associated with increased HIV risk among adolescent girls and young women (AGYW) in sub-Saharan Africa. However, little has been done to understand the dynamics of such relationships from the perspectives of either AGYW or older men, and the communities in which these relationships are embedded. This article explores the motivations and perceived benefits of such relationships for AGYW and older men, plus the social and sexual and reproductive health (SRH) consequences...
December 13, 2018: Reproductive Health
Hazel B Nichols, Minouk J Schoemaker, Jianwen Cai, Jiawei Xu, Lauren B Wright, Mark N Brook, Michael E Jones, Hans-Olov Adami, Laura Baglietto, Kimberly A Bertrand, William J Blot, Marie-Christine Boutron-Ruault, Miren Dorronsoro, Laure Dossus, A Heather Eliassen, Graham G Giles, Inger T Gram, Susan E Hankinson, Judy Hoffman-Bolton, Rudolf Kaaks, Timothy J Key, Cari M Kitahara, Susanna C Larsson, Martha Linet, Melissa A Merritt, Roger L Milne, Valeria Pala, Julie R Palmer, Petra H Peeters, Elio Riboli, Malin Sund, Rulla M Tamimi, Anne Tjønneland, Antonia Trichopoulou, Giske Ursin, Lars Vatten, Kala Visvanathan, Elisabete Weiderpass, Alicja Wolk, Wei Zheng, Clarice R Weinberg, Anthony J Swerdlow, Dale P Sandler
Background: Parity is widely recognized as protective for breast cancer, but breast cancer risk may be increased shortly after childbirth. Whether this risk varies with breastfeeding, family history of breast cancer, or specific tumor subtype has rarely been evaluated. Objective: To characterize breast cancer risk in relation to recent childbirth. Design: Pooled analysis of individual-level data from 15 prospective cohort studies. Setting: The international Premenopausal Breast Cancer Collaborative Group...
December 11, 2018: Annals of Internal Medicine
Alessandra Vecchié, Aldo Bonaventura, Federico Carbone, Davide Maggi, Antonella Ferraiolo, Beatrice Carloni, Gabriella Andraghetti, Laura Affinito Bonabello, Luca Liberale, Franco Dallegri, Fabrizio Montecucco, Renzo Cordera
Although essential for a successful pregnancy, a growing body of evidence suggests that maternal inflammation, when dysregulated, may represent a risk factor for both maternal and neonatal outcomes. Here, we assessed the accuracy of maternal C-reactive protein (CRP) concentrations at the middle phase of pregnancy in the identification of maternal adverse outcomes (MAO) until delivery. A correlation between CRP and a complicated pregnancy including both maternal and neonatal adverse outcomes has been investigated, too...
2018: BioMed Research International
Cauane Blumenberg, Daniela Zugna, Maja Popovic, Costanza Pizzi, Aluisio J D Barros, Lorenzo Richiardi
BACKGROUND: Web-based questionnaires are increasingly used in epidemiologic studies, as traditional methods are facing a decrease in response rates and an increase in costs. However, few studies have investigated factors related to the level of completion of internet-based epidemiologic questionnaires. OBJECTIVE: Our objective was to identify person-level characteristics and item design factors associated with breakoff (not finishing the questionnaire) and item nonresponse in a Web-based questionnaire...
December 7, 2018: Journal of Medical Internet Research
Antonia Scobie, Sanch Kanagarajah, Ross J Harris, Lisa Byrne, Corinne Amar, Kathie Grant, Gauri Godbole
Listeriosis is a foodborne illness that can result in septicaemia, Central Nervous System (CNS) disease, foetal loss and death in high risk patients. OBJECTIVES: To analyse the demographic trends, clinical features and treatment of non-perinatal listeriosis cases over a ten year period and identify mortality-associated risk factors. METHODS: Reported laboratory-confirmed non-pregnancy associated cases of listeriosis between 2006 and 2015 in England were included and retrospectively analysed...
December 5, 2018: Journal of Infection
Sebastian Kwiatkowski, Magdalena Bednarek-Jędrzejek, Joanna Ksel, Piotr Tousty, Ewa Kwiatkowska, Aneta Cymbaluk, Rafał Rzepka, Anita Chudecka-Głaz, Barbara Dołęgowska, Andrzej Torbè
We explored whether there was a relationship between the sFlt-1/PlGF ratio in early-late and late-onset SGA patients and whether it is associated with neonatal birth weight. MATERIAL/METHODS: 110 patients who were diagnosed with a fetal weight below the 10th percentile for gestational age and who at the same time delivered neonates with a birth weight below the 10th percentile for gestational age. For each of the patients sFlt-1, PlGF and the sFlt-1/PlGF ratio were studied and uterine artery (UtA) and umbilical artery (UA) Doppler were performed...
October 2018: Pregnancy Hypertension
Samer Tannus, Yoni Cohen, Sara Henderson, Na'ama Al Ma'mari, Tal Shavit, Weon-Young Son, Michael H Dahan
STUDY QUESTION: In IVF cycles in which the entire embryo cohort is slow growing, is it optimal to perform fresh transfer in Day 5 or to extend the culture and transfer in subsequent vitrified-warmed cycles? SUMMARY ANSWER: The outcomes depend on the degree of embryo development on Day 5. WHAT IS KNOWN ALREADY: Slow-growing blastocysts have lower implantation potential when transferred in fresh cycles. It has been suggested that embryo-endometrial asynchrony could explain this finding...
December 4, 2018: Human Reproduction
Ingrid Guerra Azevedo, Saionara Maria Aires da Câmara, Catherine McLean Pirkle, Álvaro Campos Cavalcanti Maciel, Elizabel de Souza Ramalho Viana
OBJECTIVE: Previous studies show that multiparity and a number of chronic conditions are correlated among women. Also, low respiratory muscle strength has been associated to adverse health outcomes such as chronic lung disease and early mortality. This study aimed to investigate associations between the number of lifetime pregnancies and maximal inspiratory/expiratory pressures. METHODS: In a cross-sectional study, 204 women ages 41-80 years-old, from the rural community of Santa Cruz, Brazil, provided data regarding demographics, socioeconomic characteristics, health behaviors, and number of lifetime pregnancies (≤3, 4-6 or ≥7)...
2018: PloS One
John N Chang, Everett F Magann, Sarah A Novotny, Chad E Cooley, C Heath Gauss, Marc R Parrish, John C Morrison
OBJECTIVE: To compare pregnancy outcomes in women with sickle cell disease from recent deliveries with a similar group delivered earlier. METHODS: During a 12-year period (2005-2016), data from pregnant women with hemoglobin SS or SC were collected from three university medical centers and compared with earlier studies (1979-2003) involving similar patients. The primary endpoints were maternal complications during pregnancy and newborn outcomes. RESULTS: There were 278 patients in the control group (1979-2003) compared with 150 patients in the study group (2005-2016)...
December 2018: Southern Medical Journal
Qiong Zhong, Chan Lu, Weishe Zhang, Xiangrong Zheng, Qihong Deng
BACKGROUND: Mounting evidence have linked high temperature with increased incidence of preterm birth (PTB), but which time period(s) of increase in temperature within a day and a year during pregnancy play an important role in PTB is not clarified. OBJECTIVE: This study aims to determine the critical time period(s) of heat exposure on the development of PTB by exploring the risk of PTB for temperature increase during 24 h of a whole day and each of four seasons during pregnancy...
December 2018: Journal of Thermal Biology
Yamnia I Cortés, Nisha Parikh, Matthew A Allison, Michael H Criqui, Natalie Suder, Emma Barinas-Mitchell, Christina L Wassel
OBJECTIVE: Reproductive events have been linked with increased cardiovascular risk in women, but whether they are associated with pre-clinical peripheral arterial disease (PAD) has been understudied. We evaluated associations between reproductive factors and later-life ankle-brachial index (ABI), femoral artery intima-media thickness (fIMT), and femoral plaques. METHODS: Cross-sectional analysis of 707 multiethnic women who participated in a follow-up exam of the San Diego Population Study in 2007-2011...
December 1, 2018: Journal of Women's Health
Uma Mariappen, Kevin N Keane, Peter M Hinchliffe, Satvinder S Dhaliwal, John L Yovich
Advanced age is an increasing trend for both males and females seeking in vitro fertilization (IVF). This retrospective cohort study investigated the outcomes of 1280 IVF-related treatment cycles, selecting the first treatment for couples utilizing autologous gametes and who underwent single fresh embryo transfer. Males aged 40-49 years had a 52% reduction in normal sperm motility, while it was markedly reduced by 79% at 50 years or older. However, neither semen parameters nor male age were predictive of clinical pregnancy or live birth chance...
November 29, 2018: Reproductive Biology
Sheena L P Regan, Phil G Knight, John L Yovich, Frank Arfuso, Arun Dharmarajan
OBJECTIVE: To study the effect of aging and granulosa cell growth hormone receptor (GHR) expression, and the effect of growth hormone (GH) co-treatment during IVF on receptor expression. DESIGN: Laboratory study. SETTING: University. PATIENT(S): A total of 445 follicles were collected from 62 women undergoing standard infertility treatment. INTERVENTION(S): Preovulatory ovarian follicle biopsies of granulosa cells and follicular fluid...
December 2018: Fertility and Sterility
Paulina M Merino, Patricia Lopez, Abril Salinas, Carolina Pastene, Alex Muñoz, Fernando Cassorla, Ethel Codner
STUDY OBJECTIVE: To compare ovarian function between adolescents conceived using assisted reproductive technology (AcART) and adolescents who were conceived spontaneously (AcSP). DESIGN: Multicenter study of ovarian function in AcART due to male or tubal infertility. SETTING: University Hospital PARTICIPANTS: We evaluated 22 AcART and 53 AcSP at 1-2 years after menarche. The participants were born at term (>37 weeks of gestation) with normal birthweights (>2500 g) from singleton pregnancies...
November 28, 2018: Journal of Pediatric and Adolescent Gynecology
Masumeh Babayi, Mahmood-Reza Azghani, Sakineh Hajebrahimi, Bary Berghmans
AIMS: To evaluate the role of soft tissue and ligaments damage and level of pelvic muscles activation versus intra-abdominal pressure, on pelvic organ prolapse. METHODS: This was a computational modeling based on the finite element analysis. Three pelvic muscles, four pelvic ligaments, and three organs (urethra, vagina, and rectum) were simulated. The model was subjected to total 41 472 analysis cases including three intra-abdominal pressures, two damaging levels for the ligaments, three damaging levels for the muscles, and four intentional levels of activation for muscles...
November 29, 2018: Neurourology and Urodynamics
Janicke Visser, Milla H McLachlan, Nicola Maayan, Paul Garner
BACKGROUND: Supplementary feeding may help food insecure and vulnerable people by optimising the nutritional value and adequacy of the diet, improving quality of life and improving various health parameters of disadvantaged families. In low- and middle-income countries (LMIC), the problems supplementary feeding aims to address are entangled with poverty and deprivation, the programmes are expensive and delivery is complicated. OBJECTIVES: 1. To summarise the evidence from systematic reviews of supplementary feeding for food insecure, vulnerable and malnourished populations, including children under five years of age, school-aged children, pregnant and lactating women, people with HIV or tuberculosis (or both), and older populations...
November 9, 2018: Cochrane Database of Systematic Reviews
T S Send, S Bardtke, M Gilles, I A C Wolf, M W Sütterlin, C Kirschbaum, M Laucht, S H Witt, M Rietschel, F Streit, M Deuschle
Prenatal maternal stress is an established risk factor for somatic and psychological health of the offspring. A dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in offspring has been suggested as an important mechanism. However, the impact of prenatal stress on stress reactivity in preschool-aged children is not yet well understood. This is partly due to the fact that for this age group there is no stress test as well established as for older children and adults. In the present work a previously published stress test (Kryski et al...
November 5, 2018: Psychoneuroendocrinology
Vincent Guilamo-Ramos, Alex S Bowman, Adam Benzekri, Yumary Ruiz, Oscar Beltran
OBJECTIVE: The study describes maternal and adolescent perspectives on sexual decision-making and the role of mothers in shaping use of contraception for the prevention of unplanned pregnancies and STIs among older Latino adolescents. STUDY DESIGN: Researchers used a semi-structured interview guide to conduct focus group discussions with 21 mother-adolescent Latino dyads (n=42). Latino adolescents ages 17-19 were eligible for the study. We recruited families from the South Bronx, New York City using area sampling methodology...
November 21, 2018: Contraception
A Vejen Hansen, Z Ali, S S Malchau, J Blafoss, A Pinborg, C S Ulrik
Asthma has been linked with prolonged time to pregnancy. Our aim was to explore a possible association between asthma and need for fertility treatment among women with live births.All women enrolled in the Management of Asthma during Pregnancy (MAP) program at Hvidovre Hospital (HH), Denmark, (cases) were each matched with the three consecutive women giving birth at HH (controls). Information from the Danish National Assisted Reproductive Technology registry was cross-linked with the Danish Medical Birth registry to identify live births...
November 21, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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