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Urinary leakage

Pattarin Tangtanatakul, Siriwan Klinchanhom, Pimpayao Sodsai, Thitima Sutichet, Chutipha Promjeen, Yingyos Avihingsanon, Nattiya Hirankarn
BACKGROUND: The contents of exosomes determine their biological functions and represent a new class of epigenetic modulation of renal cells considering as novel class of biomarker. OBJECTIVE: Our study aims to investigate the expression of microRNAs (miRNA), including miR-10a/b, let-7a, and miR-21, in urinary exosomes isolated from patients with active lupus nephritis (LN) compared to inactive LN. METHODS: The exosomes were obtained from long-term follow up LN patients during active and 4 months after treatment (n = 3)...
August 13, 2018: Asian Pacific Journal of Allergy and Immunology
Felix Cheung, Jaspreet S Sandhu
PURPOSE OF REVIEW: Urinary dysfunction is a common entity in patients undergoing radical pelvic surgery for non-urologic malignancies. These dysfunctions may manifest as lower urinary tract symptoms (LUTS) or signs such as urinary retention or leakage. Review of current literature is performed to describe the differing urinary dysfunctions that manifest after colorectal resection, hysterectomy, and sacrectomy. RECENT FINDINGS: Conventional radical surgery for pelvic malignancies often will result in debilitating functional problems...
August 6, 2018: Current Urology Reports
Daniel Sagalovich, Juan Garisto, Riccardo Bertolo, Nitin Yerram, Julien Dagenais, Jaya Sai Chavali, Georges-Pascal Haber, Jihad Kaouk, Robert Stein
OBJECTIVES: to describe robotic ureteroneocystostomy performed by bilateral Boari flap. METHODS: An 82 year-old female with bilateral mid ureteral strictures secondary to uterine cancer treated with radiation was managed with ureteral stenting and bilateral nephrostomy tubes. Nevertheless, patient had severe colic and recurrent urinary tract infections and thus agreed to undergo bilateral robotic ureteral reconstructive surgery. Patient positioning and ports placement were similar to those of robotic prostatectomy...
August 2, 2018: Urology
Michael X Jin, Anthony D Mohabir, Drew M Caplin, Igor Lobko, David N Siegel
This retrospective study presents three consecutive patients who underwent bilateral ureteral occlusion using the Amplatzer vascular plugs and N-butyl cyanoacrylate glue sandwich method. The patients were 63- and 65-year-old males and a 79-year-old female. Indications for the procedure included severe cystitis and complex vesicular fistulas unresponsive to urinary diversion. All three patients had immediate resolution of urinary leakage, resulting in symptom relief throughout the follow-up period. There were no procedure-related complications or side effects...
2018: Journal of Endourology Case Reports
Magdalena Hagovska, Jan Svihra, Alena Bukova, Agata Horbacz, Viera Svihrova
OBJECTIVE: The aim of this study was to determine the prevalence of SUI symptoms in sportswomen (with a high intensity of physical activity) and non-sportswomen (with a low intensity of physical activity), according to the estimated intensity of physical activity in metabolic equivalents using the IPAQ questionnaire. Another goal was to identify relationships between SUI symptoms, intensity of physical activity, and quality of life. STUDY DESIGN: A total of 1005 participants were enrolled into the study...
July 23, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Bulent Yazici, Aylin Oral, Aysegül Akgün
It is known that renal scintigraphy is the best imaging modality in the diagnosis of urinary leakage. Usually, only planar images are diagnostic but sometimes they are unclear when urinoma is small and adjacent to kidney or bladder. In other respects, planar images can be false-positive in the case of increased blood flow of abdominal wall. We suggested using SPECT/CT in differential diagnosis. An atlas of SPECT/CT is presented, which includes 3 cases that urinoma was diagnosed by SPECT/CT, which were unclear on planar images, and one case that urinary leakage suspicion on planar image was ruled out by SPECT/CT...
July 27, 2018: Clinical Nuclear Medicine
Ozer Ural Cakici, Abdullah Erdem Canda
OBJECTIVES: We investigated the use of bidirectional barbed suture only versus poliglecaprone suture with posterior rhabdosphincter reconstruction for urethro-vesical anastomosis(UVA) during robotic radical prostatectomy(RARP) on cystographic leakage, duration of catheterization and early urinary continence. METHODS: Bidirectional double-armed barbed suture only was used for UVA(n=50) in Group-1. Two 3/0 poliglecaprone 25 sutures were tied to each other to form a double-armed suture used for UVA with posterior rhabdosphincter reconstruction in Group-2(n=50)...
July 28, 2018: Journal of Endourology
Kristine Concepcion, Yan Cheng, Kevin McGeechan, Sarah Robertson, Mary Stewart, Deborah Bateson, Jane Estoesta, Pauline Chiarelli
AIMS: The study was undertaken to investigate the prevalence of urinary leakage and its associated factors among a sample of females aged 45 years and over in New South Wales. METHODS: Data were obtained from the 45 and Up Study wherein urinary leakage is identified as women who reported being troubled by leaking urine. At baseline, 143 096 females (2006-2009) and 59 060 females in the follow-up survey (2012-2015) were included in the analysis. We estimated the prevalence, and identified the factors associated with urinary leakage using logistic regression models...
July 27, 2018: Neurourology and Urodynamics
Daniel Kuetting, Claus Christian Pieper
BACKGROUND: Lower urinary tract fistulas are currently a rather rare, but severe condition associated with considerable morbidity. Treatment is challenging, especially in fistulas caused by pelvic malignancy or radiation therapy. Surgical treatment attempts fail in a considerable number of patients, especially in those with pelvic malignancies/prior radiation therapy or are precluded altogether due to severe comorbidity. For such patients percutaneous approaches can provide alternative treatment...
August 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
Tsia-Shu Lo, Nagashu Shailaja, Sandy Chua, Ling-Hong Tseng, Chuan-Chi Kao, Ming-Ping Wu
STUDY OBJECTIVE: To evaluate the clinical outcome and identify risk factors for failure of Solyx™ single-incision sling (SIS) in the treatment of urodynamic stress incontinence (USI). DESIGN: Retrospective observational study (Canadian Task Force classification II-2) SETTING: Tertiary referral center PATIENTS: Patients diagnosed with USI without needing concurrent procedures that underwent continence surgery using the Solyx SIS from February 2015 to May 2017. INTERVENTIONS: Anti-incontinence surgery MEASUREMENTS AND MAIN RESULTS: The primary outcome of this study is the rate of objective cure defined as the absence of demonstrable leakage of urine on the cough stress test and a 1-hour pad test weight of less than two grams...
July 21, 2018: Journal of Minimally Invasive Gynecology
Rachel Pope, Prakash Ganesh, Chisomo Chalamanda, William Nundwe, Jeffrey Wilkinson
INTRODUCTION: Women with vesicovaginal fistulas often experience a disruption in their normal lives, including sexual relationships, because of urinary incontinence. AIM: Although surgery repairs the urinary leakage, it is not known how surgery might affect sexual function positively or negatively. METHODS: 119 women were enrolled before surgery and interviewed including a revised Female Sexual Distress Scale (FSDS-R) score and examined for vaginal length, caliber, and pelvic floor strength...
August 2018: Journal of Sexual Medicine
Mehmet Sarier, Ibrahim Duman, Yucel Yuksel, Sabri Tekin, Mustafa Ozer, Levent Yucetin, Asuman Havva Yavuz, Alper Demirbas, Erdal Kukul
OBJECTIVE: To report our experience on the outcomes of ex vivo ureteroscopy and ex vivo pyelolithotomy carried out on the donor kidney before living donor renal transplantation. METHODS: Between 2009 and 2016, 13 stone-bearing donor kidneys underwent ex vivo bench surgery after donor nephrectomy. Of these, six patients underwent ex vivo ureteroscopy and seven patients underwent ex vivo pyelolithotomy. Data were analyzed for technical feasibility, intraoperative and postoperative complications, stone clearance, and stone recurrence...
July 19, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
Hai Wang, Zheping Zhang, Guixing Qiu, Jianguo Zhang, Jianxiong Shen
BACKGROUNDS: Rare study has been conducted to detect risk factors of perioperative complications, which are closely related to preoperative status of the patients and surgical stress. The aim of this study is to detect these relationships in degenerative scoliosis (DS) patients. METHODS: Perioperative complications of 226 cases with DS (56 males and 170 females; 65.5 ± 8.1 years old), who accepted posterior fusion in our hospital from January, 2013 to July, 2017, were retrospectively reviewed...
July 19, 2018: BMC Musculoskeletal Disorders
Wai Lun Law, Dominic C C Foo
BACKGROUND: Robotic surgery and transanal minimally invasive surgery are the two recently developed techniques, which can overcome the difficult pelvic dissection in conventional laparoscopy. This study aimed to compare the early cases of robotic and transanal total mesorectal excision (taTME) using propensity score matching. METHODS: The first 40 cases of taTME and the first 80 sphincter-saving robotic total mesorectal resection for rectal cancer were selected from the prospectively collected database...
July 16, 2018: Surgical Endoscopy
Fin Biering-Sørensen, Michael Kennelly, Thomas M Kessler, Todd Linsenmeyer, Jürgen Pannek, Lawrence Vogel, Jean-Jacques Wyndaele
Study design: Revision, review, and presentation of the International Spinal Cord Injury (SCI) Lower Urinary Tract (LUT) Function Basic Data Set (version 2.0). Objectives: Describe the revision and review and present the data set. Setting: International. Methods: The first version of the data set was revised according to new knowledge and suggestions. The review included International SCI Data Sets Committee, American Spinal Injury Association (ASIA) board, International Spinal Cord Society (ISCoS) executive and scientific committees, major organizations, and interested individuals...
2018: Spinal Cord Series and Cases
Giulio M Mari, Jacopo Crippa, Eugenio Cocozza, Mattia Berselli, Lorenzo Livraghi, Pierluigi Carzaniga, Francesco Valenti, Francesco Roscio, Giovanni Ferrari, Michele Mazzola, Carmelo Magistro, Matteo Origi, Antonello Forgione, Walter Zuliani, Ildo Scandroglio, Raffaele Pugliese, Andrea T M Costanzi, Dario Maggioni
OBJECTIVES: The aim of the present study was to compare the incidence of genitourinary (GU) dysfunction after elective laparoscopic low anterior rectal resection and total mesorectal excision (LAR + TME) with high or low ligation (LL) of the inferior mesenteric artery (IMA). Secondary aims included the incidence of anastomotic leakage and oncological outcomes. BACKGROUND: The criterion standard surgical approach for rectal cancer is LAR + TME. The level of artery ligation remains an issue related to functional outcome, anastomotic leak rate, and oncological adequacy...
July 10, 2018: Annals of Surgery
Laurent Genser, Doriane Aguanno, Hédi A Soula, Liping Dong, Laurence Trystram, Karen Assmann, Joe-Elie Salem, Jean-Christophe Vaillant, Jean-Michel Oppert, Fabienne Laugerette, Marie-Caroline Michalski, Philippe Wind, Monique Rousset, Edith Brot-Laroche, Armelle Leturque, Karine Clément, Sophie Thenet, Christine Poitou
Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammation and metabolic impairments are linked with intestinal barrier damage. However, whether intestinal permeability is altered in human obesity remains to be investigated. In a cohort of 122 severely obese and non-obese patients, we analyzed intestinal barrier function combining in vivo and ex vivo investigations. We found tight junction impairments in the jejunal epithelium of obese patients, evidenced by a reduction of occludin and tricellulin...
July 9, 2018: Journal of Pathology
Ashley Vasseur, Karine Lepigeon, David Baud, Antje Horsch, Sylvain Meyer, Yvan Vial, Chahin Achtari
INTRODUCTION AND HYPOTHESIS: Since 2006, the Lausanne University Hospital (CHUV) has offered a 12-week post-partum perineum consultation for patients with third-/fourth-degree tears, providing advice for future deliveries. This study consisted of a retrospective follow-up of these patients, focused on subsequent deliveries and current urinary and anorectal incontinence symptoms. METHODS: Patients meeting eligibility criteria were invited to complete a questionnaire on their deliveries, along with validated questionnaires grading urinary (UDI-6 and IIQ-7) and anorectal (Wexner-Vaizey score) incontinence...
July 6, 2018: International Urogynecology Journal
Ali C M Johnson, Richard A Zager
BACKGROUND: Recent clinical data support the utility/superiority of a new AKI biomarker ("NephroCheck"), the arithmetic product of urinary TIMP × IGFBP7 concentrations. However, the pathophysiologic basis for its utility remains ill defined. METHODS: To clarify this issue, CD-1 mice were subjected to either nephrotoxic (glycerol, maleate) or ischemic AKI. Urinary TIMP2/IGFBP7 concentrations were determined at 4 and 18 hours postinjury and compared with urinary albumin levels...
August 2018: Journal of the American Society of Nephrology: JASN
Young Lee, Jasmine Bhinder, Sandeep Sirsi, Dhanan Etwaru, Armand Asarian, Philip Xiao
There is lack of information in the literature on long-term complications of suprapubic catheters. The most common complications include urinary tract infection, bladder calculi, urine leakage and neoplastic changes. We report a case of an unusual complication of bladder prolapse, with subsequent diagnosis of urothelial carcinoma, leading to a necrotizing soft tissue infection after a radical cystectomy in a patient with long-term catheterization and its management. Due to the rarity of this complication, its management has not been well studied...
June 2018: Journal of Surgical Case Reports
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