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Latest medical technology

H Liu, Y Yang, Y T Lu, L M Zhu, D Zhu, Y Q Guo, W Wang, L Wei, C S Wang
Objective: To report on the two years outcome of Chinese multi-center study of the treatment of high risk non-calcified pure aortic regurgitation with transcatheter heart valve replacement (TAVR) using domestic made J-Valve™ system. Methods: The national multi-center clinical study of the treatment of high risk non-calcified pure aortic regurgitation with transcatheter heart valve replacement using domestic made J-Valve™ system was conducted during the period from April 2014 to July 2015. The follow-up time was up to 2 years...
December 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Adhra Al-Mawali, Avinash Daniel Pinto, Ali Talib Al-Hinai
To address the demands of worldwide demographic and epidemiologic changes and globalization, as well as their effects on population health, the Ministry of Health in Oman developed a long-term plan for its health system called Health Vision 2050. The plan was shaped by international consultants, who sought to augment the vision with up-to-date evidence and achieve alignment with international standards. The Health Vision 2050 main document was anchored by 24 separate strategic studies covering different dimensions and pillars of the health system, one of which was the strategic study of medical equipment and healthcare technology (MEHT)...
November 2018: Biomedical Instrumentation & Technology
Ashkan Zand, Karim Ibrahim, Archana R Sadhu
PURPOSE OF REVIEW: In the rapidly evolving and complex field of inpatient diabetes, complex care teams of physicians, nurse practitioners, physician assistants, nurses, and pharmacists are challenged to remain well informed of the latest clinical treatments and health care trends. Traditional continuing medical education (CME) and continuing education unit (CEU) strategies that require travel and/or time away from work pose a major barrier. With advancements in technology, there are media and other electronic strategies for delivering CME/ CEU that may overcome these current challenges...
November 21, 2018: Current Diabetes Reports
George Simon, Courtney D DiNardo, Koichi Takahashi, Tina Cascone, Cynthia Powers, Rick Stevens, Joshua Allen, Mara B Antonoff, Daniel Gomez, Pat Keane, Fernando Suarez Saiz, Quynh Nguyen, Emily Roarty, Sherry Pierce, Jianjun Zhang, Emily Hardeman Barnhill, Kate Lakhani, Kenna Shaw, Brett Smith, Stephen Swisher, Rob High, P Andrew Futreal, John Heymach, Lynda Chin
BACKGROUND: Rapid advances in science challenge the timely adoption of evidence-based care in community settings. To bridge the gap between what is possible and what is practiced, we researched approaches to developing an artificial intelligence (AI) application that can provide real-time patient-specific decision support. MATERIALS AND METHODS: The Oncology Expert Advisor (OEA) was designed to simulate peer-to-peer consultation with three core functions: patient history summarization, treatment options recommendation, and management advisory...
November 16, 2018: Oncologist
Lukas Gritsch, Gioacchino Conoscenti, Vincenzo La Carrubba, Patcharakamon Nooeaid, Aldo R Boccaccini
In a large number of medical devices, a key feature of a biomaterial is the ability to successfully bond to living tissues by means of engineered mechanisms such as the enhancement of biomineralization on a bone tissue engineering scaffold or the mimicking of the natural structure of the extracellular matrix (ECM). This ability is commonly referred to as "bioactivity". Materials sciences started to grow interest in it since the development of bioactive glasses by Larry Hench five decades ago. As the main goal in applications of biomedical devices and tissue scaffolds is to obtain a seamless tissue-material interface, achieving optimal bioactivity is essential for the success of most biomaterial-based tissue replacement and regenerative approaches...
January 1, 2019: Materials Science & Engineering. C, Materials for Biological Applications
Sadhana A Samant, Vinodkumar Pillai, Mahesh Gupta
Many chronic diseases are associated with unintentional loss of body weight, which is termed as cachexia. Cachexia is a complex multifactorial syndrome associated with the underlying primary disease, and characterized by loss of skeletal muscle with or without loss of fat tissue. Patients with cachexia face dire symptoms like dyspnea, fatigue, edema, exercise-intolerance and low responsiveness to medical therapy, which worsen quality of life. Since cachexia is not a stand-alone disorder, treating primary disease, such as cancer, takes precedence for the physician, and it remains mostly a neglected illness...
November 8, 2018: Canadian Journal of Physiology and Pharmacology
Aleksandra Baran-Kooiker, Marcin Czech, Coen Kooiker
Background: Multi-criteria decision analysis (MCDA) is a decision-making tool that can take into account multidimensional factors and enables comparison of (medical) technologies by combining individual criteria into one overall appraisal. The MCDA approach has slowly gained traction within Health Technology Assessment (HTA) and its elements are gradually being incorporated into HTA across Europe. Several groups of scientists have proposed MCDA approaches targeted toward orphan drugs and rare diseases by including criteria specific to rare diseases...
2018: Frontiers in Public Health
Huihui Wei, Xiaojie Duan, Wanhui Liu, Qingquan Huang, Zhaopeng Yang, Yumei Wang, Liming Xu
The reuse of high-cost single-use medical devices (SUD) is permitted in many countries, such as the United States, Germany and the United Kingdom, but strict regulatory requirements must be met. In addition to regulatory policies and regulations, such as market access mode and special requirements on Good Manufacture Practice (GMP), there are strict technical requirements on the potential risk control and quality assurance system. Therefore, effective risk assessment and risk control technology are the keys to ensure effective quality control and safe use of SUDs...
September 30, 2018: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
Eiji Kobayashi
Technological advances such as optical instruments and surgical tools have enabled the considerable contributions of microsurgery to surgical therapies. Accordingly, surgical therapeutics has provided the latest information across a wide range of medical specialties, including immunology and pharmacology, despite specialization according to organs and organ systems. The International Society for Experimental Microsurgery, an academic organization, has utilized experimental microsurgery technology in the identification of curative concepts for diseases that remain difficult to treat...
September 2018: Acta Cirúrgica Brasileira
Bhawna Dhruv, Neetu Mittal, Megha Modi
Medical field has highly evolved with advancements in the technologies which prove to be beneficial for radiologists and patients for better diagnosis. The era of medical science provides best healthcare solutions with the help of medical images. Till now, 2D MRIs played a prominent role in early detection of disease but with latest technologies taking over the charge, 3D MRIs are highly effective and great in demand now-a-days. With the aid of advanced techniques such as edge detection, segmentation and texture analysis on these images the disease detection may become much easier...
October 12, 2018: International Journal of Neuroscience
Roohi Jeelani, Gretchen G Collins, Angeline Beltsos, William G Kearns
Conferences serve an essential means of learning and staying up to date in all aspects of medicine. Reproductive endocrinology and infertility is a young and constantly evolving field. The Midwest Reproductive Symposium International (MRSi) is a yearly conference held in Chicago, IL, and is one of the most intimate yet influential conferences in the fertility world. This conference is geared towards all professions and roles in the fertility world such as physicians, geneticists, nurses, allied health professionals, basic scientists, mental health professionals, business administration professionals, reproductive endocrinology and infertility fellows, and obstetrics and gynecology residents alike...
September 27, 2018: Journal of Assisted Reproduction and Genetics
Pankaj Chandak, Nicholas Byrne, Andrew Coleman, Narayan Karunanithy, Jim Carmichael, Stephen D Marks, Jelena Stojanovic, Nicos Kessaris, Nizam Mamode
OBJECTIVE: The authors investigated a novel application of patient-specific three-dimensional (3D) printing, to enhance preoperative, multidisciplinary planning in complex, living-donor pediatric renal transplantation. SUMMARY BACKGROUND DATA: For children with end-stage kidney disease, the transplantation of adult-sized, living-donor kidneys into small recipients (<20 kg) with increasingly complex structural anomalies can be difficult. Establishing the operative feasibility in such cases demands a surgical understanding of anatomy to be derived from medical imaging...
September 20, 2018: Annals of Surgery
Qiusha Min, Zhifeng Wang, Neng Liu
Despite the fact that a large number of web applications are used in the medical community, there are still certain technological challenges that need to be addressed, for example, browser plug-ins and efficient 3D visualization. These problems make it necessary for a specific browser plug-in to be preinstalled on the client side when launching applications. Otherwise, the applications fail to run due to the lack of the required software. This paper presents the latest techniques in hypertext markup language 5 (HTML5) and web graphics library (WebGL) for solving these problems and an evaluation of the suitability of the combination of HTML5 and WebGL for the development of web-based medical imaging applications...
2018: Journal of Healthcare Engineering
Omar S Ahmad, Thomas S Bedwell, Cem Esen, Alvaro Garcia-Cruz, Sergey A Piletsky
Molecular imprinting is the process of template-induced formation of specific recognition sites in a polymer. Synthetic receptors prepared using molecular imprinting possess a unique combination of properties such as robustness, high affinity, specificity, and low-cost production, which makes them attractive alternatives to natural receptors. Improvements in polymer science and nanotechnology have contributed to enhanced performance of molecularly imprinted polymer (MIP) sensors. Encouragingly, recent years have seen an increase in high-quality publications describing MIP sensors for the determination of biomolecules, drugs of abuse, and explosives, driving toward applications of this technology in medical and forensic diagnostics...
September 18, 2018: Trends in Biotechnology
Vaia Florou, Antonio G Nascimento, Ashish Gulia, Gilberto de Lima Lopes
Sarcomas, rare and heterogenous malignancies that comprise less than 1% of all cancers, have poor outcomes in the metastatic and refractory setting. Their management requires a multidisciplinary approach that consists of medical and surgical oncologists, radiation oncologists, and pathologists as well as ancillary support. In addition to systemic treatments, most patients will require surgical resection and radiation therapy, which mandates the use of the latest technologies and specialized expertise. Management guidelines have been developed in high-income countries, but their applicability in low-income countries, where resources may be limited, remains a challenge...
May 23, 2018: American Society of Clinical Oncology Educational Book
S Joseph Sirintrapun, Ana Maria Lopez
Telemedicine uses telecommunications technology as a tool to deliver health care to populations with limited access to care. Telemedicine has been tested in multiple clinical settings, demonstrating at least equivalency to in-person care and high levels of patient and health professional satisfaction. Teleoncology has been demonstrated to improve access to care and decrease health care costs. Teleconsultations may take place in a synchronous, asynchronous, or blended format. Examples of successful teleoncology applications include cancer telegenetics, bundling of cancer-related teleapplications, remote chemotherapy supervision, symptom management, survivorship care, palliative care, and approaches to increase access to cancer clinical trials...
May 23, 2018: American Society of Clinical Oncology Educational Book
Ahmad Mobed, Mohammad Hasanzadeh, Mohammad Agazadeh, Ahad Mokhtarzadeh, Mohammad Ahangarzadeh Rezaee, Javid Sadeghi
Fastidious bacteria are group of bacteria that not only grow slowly but also have complex nutritional needs. In this review, recent progress made on development of biosensing strategies towards quantification of Legionella pneumophila as fastidious bacteria in microbiology was investigated. In coincidence with medical bacteriology, it is the most widely used bio-monitoring, biosensors based on DNA and antibody. Also, all of legionella pneumophila genosensors and immunosensors that developed in recent years were collected analyzed...
January 2019: International Journal of Biological Macromolecules
Mario Rothbauer, Julie M Rosser, Helene Zirath, Peter Ertl
Organ-on-a-chip technology offers the potential to recapitulate human physiology by keeping human cells in a precisely controlled and artificial tissue-like microenvironment. The current and potential advantages of organs-on-chips over conventional cell cultures systems and animal models have captured the attention of scientists, clinicians and policymakers as well as advocacy groups in the past few years. Recent advances in tissue engineering and stem cell research are also aiding the development of clinically relevant chip-based organ and diseases models with organ level physiology for drug screening, biomedical research and personalized medicine...
September 3, 2018: Current Opinion in Biotechnology
Gilles Sebastiaan van Tienderen, Marius Berthel, Zhilian Yue, Mark Cook, Xiao Liu, Stephen Beirne, Gordon G Wallace
INTRODUCTION: Epilepsy is a chronic brain disease characterized by unprovoked seizures, which can have severe consequences including loss of awareness and death. Currently, 30% of epileptic patients do not receive adequate seizure alleviation from oral routes of medication. Over the last decade, local drug delivery to the focal area of the brain where the seizure originates has emerged as a potential alternative and may be achieved through the fabrication of drug-loaded polymeric implants for controlled on-site delivery...
September 2018: Expert Opinion on Drug Delivery
Rosario Mendoza, Teresa Jáuregui, Maria Diaz-Nuñez, Mariana de la Sota, Alaitz Hidalgo, Marcos Ferrando, Lorea Martínez-Indart, Antonia Expósito, Roberto Matorras
Background: The number of multiple pregnancies has been significantly increased in the last decades due to assisted reproduction techniques development. Compared to singleton, twins and multiple pregnancies are associated to more complications and risks for both mother and children. The objective of this study was to examine the proportion of patients preferring a multiple birth over a singleton after an IVF/ICSI attempt, their reasons and the influence of socio-demographic and clinical parameters on their preference...
July 2018: Journal of Reproduction & Infertility
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