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Age more than 16

Wendy C King, Amanda S Hinerman, Steven H Belle, Abdus S Wahed, Anita P Courcoulas
Importance: Estimates of weight regain following bariatric surgery vary widely. Objective: To describe weight regain after reaching nadir weight following Roux-en-Y gastric bypass (RYGB) surgery and compare weight regain measures for association with outcomes. Design, Setting, and Participants: Prospective cohort study of 2458 adults who underwent bariatric surgery at 10 hospitals in 6 US cities between March 2006 and April 2009. Assessments were conducted within 30 days' presurgery, at 6 months' postsurgery, and then annually until January 2015...
October 16, 2018: JAMA: the Journal of the American Medical Association
G Nina Lu, Mark R Villwock, Clinton D Humphrey, J David Kriet, Andrés M Bur
Importance: Facial reanimation procedures share the same surgical field as a parotidectomy and are most easily accomplished at the time of facial nerve sacrifice. Early reanimation would also reduce the duration of paralysis and may lead to better functional outcomes. Objective: To assess the incidence and types of facial nerve reanimation performed concurrently with total parotidectomy and facial nerve sacrifice using the American College of Surgeons National Surgical Quality Improvement Project (ACS-NSQIP) database...
September 20, 2018: JAMA Facial Plastic Surgery
Frances Rice, Lucy Riglin, Ajay K Thapar, Jon Heron, Richard Anney, Michael C O'Donovan, Anita Thapar
Importance: Depression often first manifests in adolescence. Thereafter, individual trajectories vary substantially, but it is not known what shapes depression trajectories in youth. Adult studies suggest that genetic risk for schizophrenia, a psychiatric disorder with a neurodevelopmental component, may contribute to an earlier onset of depression. Objective: To test the hypothesis that there are distinct trajectories of depressive symptoms and that genetic liability for neurodevelopmental psychiatric disorders (eg, schizophrenia, attention deficit/hyperactivity disorder [ADHD]), as well as for major depressive disorder (MDD), contribute to early-onset depression...
October 14, 2018: JAMA Psychiatry
Po-Hong Liu, Kana Wu, Kimmie Ng, Ann G Zauber, Long H Nguyen, Mingyang Song, Xiaosheng He, Charles S Fuchs, Shuji Ogino, Walter C Willett, Andrew T Chan, Edward L Giovannucci, Yin Cao
Importance: Colorectal cancer (CRC) incidence and mortality among individuals younger than 50 years (early-onset CRC) are increasing. The reasons for such increases are largely unknown, although the increasing prevalence of obesity may be partially responsible. Objective: To investigate prospectively the association between obesity and weight gain since early adulthood with the risk of early-onset CRC. Design, Setting, and Participants: The Nurses' Health Study II is a prospective, ongoing cohort study of US female nurses aged 25 to 42 years at study enrollment (1989)...
October 11, 2018: JAMA Oncology
Andrew G Herzog, Hannah B Mandle, Devon B MacEachern
Importance: If unintended pregnancy is common among women with epilepsy and is associated with increased risk of spontaneous fetal loss (SFL), it is important to develop guidelines for safe and effective contraception for this community. Objective: To assess whether planned pregnancy is a determinant of SFL in women with epilepsy. Design, Setting, and Participants: The Epilepsy Birth Control Registry conducted this web-based, retrospective survey between 2010 and 2014...
October 15, 2018: JAMA Neurology
Kelvin Robertson, Laurence A G Marshman, David Plummer, Elena Downs
Importance: Optimal pharmacologic treatment for chronic sciatica (CS) is currently unclear. While gabapentin (GBP) and pregabalin (PGB) are both used to treat CS, equipoise exists. Nevertheless, pharmaceutical regulation authorities typically subsidize one drug over the other. This hinders interchange wherever the favored drug is either ineffective or ill-tolerated. Objective: To assess GBP vs PGB head to head for the treatment of CS. Design, Setting, and Participants: A preplanned interim analysis of a randomized, double-blind, double-dummy crossover trial of PGB vs GBP for management of CS at half the estimated final sample size was performed in a single-center, tertiary referral public hospital...
October 15, 2018: JAMA Neurology
Christine E Haugen, Courtenay M Holscher, Jacqueline Garonzik-Wang, Marcos Pozo, Fatima Warsame, Mara McAdams-DeMarco, Dorry L Segev
OBJECTIVES: To explore trends in liver transplantation (LT) and outcomes for older recipients for evaluation, counseling, and appropriate referral of this vulnerable group of older adults. DESIGN: Prospective national cohort study. SETTING: Scientific Registry of Transplant Recipients (January 1, 2003-December 31, 2016). PARTICIPANTS: Older (aged ≥ 65) deceased donor liver-only transplant recipients (n=8,627). MEASUREMENTS: We evaluated temporal changes in recipient, donor, and transplant characteristics and post-LT length of stay (LOS), acute rejection, graft loss, and mortality using logistic regression and Cox proportional hazards...
October 16, 2018: Journal of the American Geriatrics Society
Rim Charfi, Ramla Mizouri, Mouna Ben Sassi, Hanene Eljebari, Nadia Jebabli, Fatma Ben Salem, Sarra Zerei, Ali Mrabet, Riadh Daghfous, Anis Klouz, Issam Salouage, Emna Gaies, Sameh Trabelsi
OBJECTIVE: In this study, we aimed to analyze the trough plasmatic levels (C0) of the antiepileptic drugs (AED) administered by nasogastric tubes (NGT) in comatose patients and to draw up recommendations for therapeutic drug monitoring (TDM) and for the modalities of AED administration by NGT. METHODS: We conducted a retrospective study on comatose patients addressed over six years and 10 months in Clinical Pharmacology for C0 measurement of AED administered by NGT...
February 2018: La Tunisie Médicale
Sanni Yaya, Ruoxi Wang, Tang Shangfeng, Bishwajit Ghose
Abstract: Heavy consumption of alcohol has shown to be associated with sleep disturbances among adult and elderly people in high income settings. So far, the relationship between alcohol drinking and sleeping pattern has not been studied in an African setting. Therefore, in this study we investigated whether alcohol consumption has any influence on sleeping hours among adult men and women in Ghana. Methods: Data for this survey were extracted from Ghana Demographic and Health Survey (GDHS 2008)...
2018: PeerJ
Ichiro Okano, Yuki Midorikawa, Natsuki Midorikawa, Yushi Hoshino, Takatoshi Sawada, Tomoaki Toyone, Katsunori Inagaki
Study design: Single-center, retrospective case-control study. Objectives: This study aimed to determine the risk factors for progression of neurological symptoms after anterior fusion for cervical spine trauma with no or incomplete spinal cord injury. Setting: Community-based hospital with an acute care center in Japan. Methods: We retrospectively reviewed 54 consecutive unstable subaxial cervical spine fracture/dislocation cases that had undergone surgical treatment...
2018: Spinal Cord Series and Cases
Youngsuk Lim, Chorong Kim, Haeryun Park, Sooyoun Kwon, Oksun Kim, Heeyoung Kim, Youngmi Lee
BACKGROUND/OBJECTIVES: The objective of this study was to determine dysphagia risk among community-dwelling elderly people living at home. We also examined the impact of socio-demographic variables on dysphagia risk as well as the relationship between dysphagia risk and dietary characteristics. SUBJECTS/METHODS: The study sample included 568 community-dwelling individuals, aged 65 years and above, who were living independently in their own home in Seoul, Gyeonggi, or Gwangju in South Korea...
October 2018: Nutrition Research and Practice
Alva Tang, Natalie Slopen, Charles A Nelson, Charles H Zeanah, Michael K Georgieff, Nathan A Fox
BACKGROUND: Reduced prenatal growth followed by rapid postnatal weight gain are risk factors for developing metabolic and cardiovascular disease. Children reared in institutions experience a similar pattern of growth restriction followed by catch-up growth after removal. We explored whether patterns of catch-up growth affect metabolic and cardiovascular outcomes in previously institutionalized adolescents. METHOD: A longitudinal study of institutionalized infants randomized to care as usual (n = 68) or foster care intervention (n = 68), and never institutionalized controls (n = 127)...
October 1, 2018: Pediatric Research
Claudia N Orozco-González, Laura Cortés-Sanabria, Alfonso M Cueto-Manzano, Beatriz Corona-Figueroa, Héctor R Martínez-Ramírez, Jorge López-Leal, Fabiola Martín-Del-Campo, Enrique Rojas-Campos, Benjamín Gómez-Navarro
OBJECTIVE: Pica could be strongly implicated in nutritional status of patients on dialysis; however, very scarce data are currently available. The objective of this study was to evaluate the prevalence of pica and its association with nutritional status in dialysis patients. DESIGN AND METHODS: This is a cross-sectional study in a tertiary care teaching hospital. Four-hundred patients on dialysis, without previous pica diagnosis or transplant, pregnancy, mental illness, or infection, were included in the study...
October 12, 2018: Journal of Renal Nutrition
Damien Subtil, Gilles Brabant, Emma Tilloy, Patrick Devos, Frédérique Canis, Annie Fruchart, Marie-Christine Bissinger, Jean-Charles Dugimont, Catherine Nolf, Christophe Hacot, Sophie Gautier, Jérôme Chantrel, Marielle Jousse, David Desseauve, Jean Louis Plennevaux, Christine Delaeter, Sylvie Deghilage, Anne Personne, Emmanuelle Joyez, Elisabeth Guinard, Eric Kipnis, Karine Faure, Bruno Grandbastien, Pierre-Yves Ancel, François Goffinet, Rodrigue Dessein
BACKGROUND: Preterm delivery during pregnancy (<37 weeks' gestation) is a leading cause of perinatal mortality and morbidity. Treating bacterial vaginosis during pregnancy can reduce poor outcomes, such as preterm birth. We aimed to investigate whether treatment of bacterial vaginosis decreases late miscarriages or spontaneous very preterm birth. METHODS: PREMEVA was a double-blind randomised controlled trial done in 40 French centres. Women aged 18 years or older with bacterial vaginosis and low-risk pregnancy were eligible for inclusion and were randomly assigned (2:1) to three parallel groups: single-course or triple-course 300 mg clindamycin twice-daily for 4 days, or placebo...
October 12, 2018: Lancet
Catherine Arsenault, Keely Jordan, Dennis Lee, Girmaye Dinsa, Fatuma Manzi, Tanya Marchant, Margaret E Kruk
BACKGROUND: Emerging data show that many low-income and middle-income country (LMIC) health systems struggle to consistently provide good-quality care. Although monitoring of inequalities in access to health services has been the focus of major international efforts, inequalities in health-care quality have not been systematically examined. METHODS: Using the most recent (2007-16) Demographic and Health Surveys and Multiple Indicator Cluster Surveys in 91 LMICs, we described antenatal care quality based on receipt of three essential services (blood pressure monitoring and urine and blood testing) among women who had at least one visit with a skilled antenatal-care provider...
November 2018: Lancet Global Health
Laura Sommerauer, Alois Philipp, Matthias Lubnow, Thomas Müller, Dirk Lunz, Hans-Stefan Hofmann, Michael Ried
INTRODUCTION: Patients with severe respiratory failure and veno-venous extracorporeal membrane oxygenation (vv-ECMO) often require diagnostic or therapeutic thoracic surgery. METHODS: Retrospective analysis of prospectively collected data (Regensburg ECMO Registry) on all patients requiring vv-ECMO between December 2010 and December 2016 due to acute lung failure (ALF) with diagnostic or therapeutic thoracic surgery. Endpoints were the indications for thoracic surgery as well as postoperative morbidity and in-hospital mortality...
October 15, 2018: Zentralblatt Für Chirurgie
Victoria L Mango, Donna D'Alessio, Elizabeth A Morris, Richard Ha, Blanca Bernard-Davila, Maxine Jochelson
OBJECTIVE: Prior to stereotactic breast biopsy, some radiologists obtain a mammogram image with an overlying alphanumeric grid to mark the skin overlying the target. Our purpose is to determine if this grid image affects stereotactic biopsy efficiency and accuracy, including total images obtained, procedure time and need for retargeting. MATERIALS AND METHODS: IRB approved, HIPAA compliant retrospective review of prone stereotactic biopsy cases targeting calcifications 9/1/2015 to 9/1/2016 was performed...
October 6, 2018: Clinical Imaging
Andrew K G Tan, Steven T Yen, Xiangming Fang, Fu-Sung Chiang
Background: This study examined the factors associated with body mass index (BMI) categories of Malaysian adolescents by physical activity (PA) status. Methods: Data were obtained from the 2012 Malaysia Global School-based Student Health Survey. Generalized ordered logit regression analysis was conducted on 24 339 adolescents by PA status. Results: Early- (ages 11-13) and middle-stage (ages 14-16) adolescents were associated with higher overweight and obesity risks than their older peers (ages 17-18)...
October 15, 2018: International Health
Alby Elias, Tia Cummins, Regan Tyrrell, Fiona Lamb, Vincent Dore, Robert Williams, Jeffrey Rosenfeld, Malcolm Hopwood, Victor L Villemagne, Christopher C Rowe
BACKGROUND: An association between obstructive sleep apnea (OSA) and Alzheimer's disease has been suggested but little is known about amyloid-β and tau deposition in this syndrome. OBJECTIVE: To determine amyloid and tau burden and cognitive function in OSA in comparison to those without a diagnosis of OSA. METHODS: The status of OSA was determined by asking participants about history of polysomnographic diagnosis of OSA and the use of Continuous Positive Airway Pressure (CPAP)...
October 8, 2018: Journal of Alzheimer's Disease: JAD
Joana Ribeiro da Silva, Luísa Proença, Adélia Rodrigues, Rolando Pinho, Ana Ponte, Jaime Rodrigues, Mafalda Sousa, Rita Almeida, João Carvalho
Background: Obesity is an increasing worldwide problem associated with a vast number of comorbidities. Decreasing body weight by only 5-10% has been shown to slow and even prevent the onset of obesity-related comorbidities. Between pharmacological therapy and bariatric surgery a great variety of endoscopic techniques are available, the most common being intragastric balloon (IGB). The purpose of this study was to assess the safety, tolerance, and kinetics of IGBs in weight loss. The kinetics of weight loss were evaluated in 2 different contexts and phases: after the IGB's removal and after follow-up that varied between 6 and 12 months...
September 2018: GE Portuguese Journal of Gastroenterology
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