keyword
https://read.qxmd.com/read/38024078/exploring-the-indications-levels-and-outcomes-of-lower-extremity-amputation-at-a-tertiary-care-hospital-in-pakistan
#1
JOURNAL ARTICLE
Malik Amna Khatoon, Syed Muhammad Khalid Karim, Laraib Khan, Sundas Karimi, Umar Farooq Abro
BACKGROUND: Lower extremity amputation (LEA) is a surgical procedure performed to remove either a part or the entire lower limb due to medical conditions such as trauma, infection, peripheral vascular disease, or malignancy. The procedure is becoming increasingly common in Pakistan, with a bulk of patients presenting from rural areas in tertiary care centers. Understanding the indications, levels, and outcomes of LEA is essential for improving patient care and adopting preventive strategies, especially in developing countries...
November 2023: Curēus
https://read.qxmd.com/read/37772210/assessment-of-type-2-diabetes-awareness-and-knowledge-in-the-non-medical-bahraini-population
#2
JOURNAL ARTICLE
Saeed H Khalaf, Aysha S Waheed, Noora A Ali, Noor J AlNajem, Rawan M Abdulrahman, Zainab J Hasan
Background With type 2 diabetes (T2D) posing an escalating health challenge to the Kingdom of Bahrain, enhancing public awareness becomes instrumental in mitigating disease outcomes. This study aimed to appraise the level of T2D awareness among the non-medical Bahraini population by evaluating their understanding of the disease, its risk factors, symptoms, complications, monitoring, and prevention methods. Methods We conducted a cross-sectional study from March 2022 to June 2022. The study employed an electronic survey using Google® Forms (Google LLC, Mountain View, California, USA) targeting non-healthcare workers aged 15 and above...
August 2023: Curēus
https://read.qxmd.com/read/37641775/euglycemic-diabetic-ketoacidosis-in-a-patient-with-urinary-tract-infection
#3
Sridhar Reddy Patlolla, Janaki Devara, Muhammad Atif Ameer, Prasanthy Reddy Patlolla, Madhusudhan Ponnala
Diabetes Mellitus (DM) is a complex metabolic disease primarily associated with elevated blood glucose levels in the body. Diabetic ketoacidosis (DKA) is the most feared acute presentation of diabetes mellitus (DM) in both type 1 and type 2 diabetes mellitus. Furthermore, euglycemic diabetic ketoacidosis (EDKA) is a relatively rare complication of DM in which the blood glucose levels are usually less than 250 mg/dl with an elevated anion gap metabolic acidosis. It can be a diagnostic challenge due to normal blood glucose levels and often can be overlooked...
July 2023: Curēus
https://read.qxmd.com/read/36381918/unique-case-of-a-refractory-esophageal-peptic-stricture-in-an-uncontrolled-diabetic
#4
Vincent Wong, Anjella Manoharan, Dayna Panchal, Weizheng Wang
Esophageal strictures can lead to the narrowing of the esophagus and dysphagia. They are termed peptic strictures when caused by acid reflux and usually measure less than two centimeters in the lower esophagus. Peptic strictures can be treated with proton pump inhibitors, endoscopic dilation, and esophagectomy. We present a unique case of a young diabetic who developed progressive dysphagia and was found to have a 5-centimeter esophageal peptic stricture refractory to treatment. His symptoms were secondary to gastroparesis and acid reflux from uncontrolled diabetes...
October 2022: Curēus
https://read.qxmd.com/read/36303801/effect-of-dolutegravir-on-plasma-glucose-among-human-immunodeficiency-virus-patients-in-a-community-health-center-setting
#5
JOURNAL ARTICLE
Foud Bahamdain
Background Dolutegravir has become one of the initial backbones in antiretroviral therapy regimens for most patients with HIV in several recent clinical guidelines. However, dolutegravir has been associated with severe cases of hyperglycemia and the new-onset of diabetes in multiple case reports and clinical trials. A community health center noticed an increasing number of new-onset hyperglycemia incidences in patients on dolutegravir. Method Retrospective chart review of patients who started on dolutegravir or dolutegravir combination regimen (Triumreq®, Juluca®, GlaxoSmithKline (GSK), Research Triangle Park, NC) between the dates of January 1st, 2013 and January 1st, 2018 who have been treated in community healthcare centers...
October 2022: Curēus
https://read.qxmd.com/read/35755551/diabetes-mellitus-and-related-admission-factors-among-hospitalized-patients-in-king-abdul-aziz-university-hospital-in-jeddah-saudi-arabia
#6
JOURNAL ARTICLE
Yasamen A Shikdar, Hala H Mosli, Nasrin A Shikdar, Rajaa M Alshanketi, Noorah A Shikdar, Raghdaa M Malebary, Wedyan M Aboznadah, Mohammad A Shikdar
Background Diabetes mellitus (DM) is a rapidly increasing serious health problem that affects the population all over the world. The increasing prevalence of DM in Saudi Arabia is reflected in our hospital admissions as well. This study aimed to assess the proportion of DM (including type 1 and type 2 diabetes) among hospitalized patients and the reasons for admissions to the medical unit at King Abdul-Aziz University Hospital (KAUH) in Jeddah, Saudi Arabia. Methods We conducted a hospital record-based cross-sectional study at KAUH from January to April 2021...
May 2022: Curēus
https://read.qxmd.com/read/35371807/linear-growth-and-final-height-in-people-with-type-1-diabetes-a-study-from-karachi-pakistan
#7
JOURNAL ARTICLE
Wajid Shaikh, Musarrat Riaz, Saima Askari, Abdul Basit
Objective In this study, we aimed to determine the linear growth and final height in children/adolescents with type 1 diabetes mellitus (T1DM) at a tertiary care hospital. Methodology This observational study was conducted at the Baqai Institute of Diabetology and Endocrinology (BIDE), Baqai Medical University, Karachi, Pakistan. All children/adolescents diagnosed with T1DM of either gender aged between 8-18 years visiting the outpatient department of BIDE were included after obtaining informed consent. A predesigned questionnaire was developed to record data...
February 2022: Curēus
https://read.qxmd.com/read/34336528/incidence-and-predictors-of-in-hospital-mortality-among-diabetics-undergoing-transcatheter-aortic-valve-replacement
#8
JOURNAL ARTICLE
Jannat Malik, Jeet R Patel, Hajara Joundi, Kristal N Pereira, Amanpreet K Pannu, Goher Haneef, Khadija T Kubra, Keerthika Mathialagan, Temitope Ajibawo
Objectives The main goals of this study are to delineate the differences in demographics, comorbidities and hospital outcomes between diabetic and non-diabetic aortic stenosis (AS) patients, and next is to evaluate the predictors of in-hospital mortality in AS patients undergoing transcatheter aortic valve replacement (TAVR). Methods We conducted an observational cross-sectional study using the nationwide inpatient sample (NIS) and included 33,325 adult patients with a primary discharge diagnosis of AS who underwent TAVR during the hospitalization...
June 2021: Curēus
https://read.qxmd.com/read/30811546/longitudinal-changes-in-corneal-cell-and-nerve-fiber-morphology-in-young-patients-with-type-1-diabetes-with-and-without-diabetic-retinopathy-a-2-year-follow-up-study
#9
JOURNAL ARTICLE
Eszter A Deák, Eszter Szalai, Noémi Tóth, Rayaz A Malik, András Berta, Adrienne Csutak
Purpose: We have previously used in vivo corneal confocal microscopy (IVCCM) to demonstrate significant alterations in the corneal epithelial cells, stromal keratocytes, and subbasal nerves in young patients with type 1 diabetes mellitis (T1DM), especially those with diabetic retinopathy (DR). We have evaluated the change in corneal cellular and subbasal nerve morphology over 2 years in young patients with T1DM with or without DR. Methods: A total of 19 patients with T1DM, without (n = 12) and with (n = 7) DR and 19 age- and sex-matched healthy control subjects underwent quantification of corneal cellular and subbasal nerve plexus morphology by using IVCCM at baseline and after 2 years...
February 1, 2019: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/29725969/differences-in-glycemic-control-in-diabetic-and-non-diabetic-patients-with-parenteral-nutrition-using-a-basal-plus-correction-insulin-regimen-an-observational-retrospective-study
#10
JOURNAL ARTICLE
Analía Ramos, Fernanda Rabasa, Lilian Mendoza, Joana Cardenete, Pedro Gill, Alba Morilla, Daniel Cardona, Antonio Pérez
INTRODUCTION: Hyperglycemia is a frequent complication of parenteral nutrition (PN) in patients both with and without diabetes mellitis (DM). The aim of this study was to evaluate the quality of glucose control achieved with basal plus-correction insulin in surgical patients with and without a history of DM receiving PN. METHODS: Retrospective evaluation of a protocol applied during the period of January 2013-December 2015. The insulin dose was started at 0.4 and 0...
June 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/27004352/euglycemic-diabetic-ketoacidosis-and-severe-acute-kidney-injury-secondary-to-off-label-use-of-sodium-glucose-cotransporter-2-inhibitor-in-a-type-1-diabetic-patient
#11
JOURNAL ARTICLE
Hassan Tahir, Adil Wani, Vistasp Daruwalla, Nour Daboul, Jahnavi Sagi
Sodium glucose Cotransporter-2 (SGLT2) inhibitors are a new class of drug approved for the treatment of type-2 diabetes; however they are also increasingly used off label in type-1 diabetic patients. SGLT2 Inhibitors work by increasing glucose excretion in urine. Euglycemic diabetic ketoacidosis (DKA) is potentially life threatening side effect as patients have normal glucose and minimal symptoms thus delaying diagnosis and treatment. Our case report highlights the risk of using SGLT2 inhibitors in type-1 diabetes and also supports the need for long term studies to define clear efficacy and complications of SGLT 2 inhibitors in both type-1 and type 2 diabetes mellitis...
October 2015: Journal of Ayub Medical College, Abbottabad: JAMC
https://read.qxmd.com/read/26111133/effects-of-osteopathic-manipulative-treatment-on-diabetic-gastroparesis
#12
JOURNAL ARTICLE
Valerie J Van Ravenswaay, Simeon J Hain, Sierra Grasso, Jay H Shubrook
As the number of diagnoses of diabetes mellitis continues to increase, so does the incidence of diabetic complications, such as gastroparesis. The current case report examines the effect of osteopathic manipulative treatment (OMT) on the symptoms of diabetic gastroparesis in a patient with type 1 diabetes mellitus. After a prescribed regimen of OMT, the patient's Gastroparesis Cardinal Symptom Index score improved from 13 to 8, and his hospitalization stays decreased from once every 6 to 8 weeks to once in 6 months...
July 2015: Journal of the American Osteopathic Association
https://read.qxmd.com/read/25077361/investigation-of-the-effects-of-propofol-and-vitamin-c-administration-on-erythrocyte-deformability-in-rats-with-streptozotocin-induced-diabetes-mellitis
#13
JOURNAL ARTICLE
F M Comu, L Ozturk, M Alkan, K Pampal, M Arslan, B Isik, M S Atac, D Yilmaz
PURPOSE: In the current study we aim to investigate the effects of vitamin C and profol on red blood cell deformability in diabetic rats. MATERIALS AND METHODS: Twenty- eight Wistar Albino rats were included in the study after streptozocin (60 mg/kg) treatment for 4 weeks of observation for diabetes presence. Twenty-eight rats were allocated to 4 groups. In group DP (n = 7) 150 mg.kg-1 of propofol was injected intraperitoneally. In group DP-vit C (n = 7) rats 100 mg/kg of vitamin C (Ascorbic acid, Redoxon® 1000 mg/5 mL - Roche) were applied one hour before administrating 150 mg...
2014: Bratislavské Lekárske Listy
https://read.qxmd.com/read/23677911/aspirin-half-maximal-inhibitory-concentration-value-on-platelet-cyclooxygenase1-in-severe-type-2-diabetes-mellitus-is-not-significantly-different-from-that-of-healthy-individuals
#14
JOURNAL ARTICLE
Yukio Kimura, Katsuhiro Takano, Kaneo Satoh, Kaoru Aida, Tetsuro Kobayashi, Yukio Ozaki
It is implicated that diabetic patients are more resistant to aspirin therapy than patients with other diseases or healthy individuals. We evaluated the inhibitory effects of aspirin on aggregation and the cyclooxygenase activity of platelets of 10 patients with severe type-2 diabetes mellitis (DM) and compared the results with those of healthy individuals. Although platelet aggregation had a tendency to be more resistant to aspirin with the DM group, there was no significant difference in half maximal inhibitory concentration 50 values of aspirin on the cyclooxygenase activity between the patients with DM and healthy individuals...
September 2014: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/23413688/-the-influence-of-afobazole-on-biochemical-and-histo-patho-morphological-parameters-of-endothelial-function-at-experimental-diabetes-mellitis-in-rats
#15
JOURNAL ARTICLE
S G Dzugkoev, K M Kozyrev, N G gumanova, F S Dzugkoeva
Oxidizing stress in rats with experimental diabetes mellitis is accompanied by endothelial dysfunction develops. Its biochemical markers are the increase of concentration of blood MDA, the impairments of cell antioxidant depence and a decrease in concentration of total metabolites of NO and expression of endothelial NO-synthetase (e-NOS). Biochemical changes are considered with histopathomorphologic impairments of aortic endothelium. Treatment with afobazole suppressed free-radical oxidation, increased activity of SOD and concentration of total metabolites of NO and a level of eNOS expression and also restored of a histologic pattern of aortic endothelium due to activation of nucleocytoplasmic regenerative processes...
July 2012: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://read.qxmd.com/read/21688766/photographic-diabetic-retinopathy-screening-in-an-urban-family-practice-clinic-effect-on-compliance-to-eye-examination
#16
JOURNAL ARTICLE
Sanket U Shah, JoAnn Seibles, Susanna S Park
BACKGROUND AND OBJECTIVE: This study assessed the effect of introduction of diabetic retinopathy screening using non-mydriatic digital fundus photography (nDFP) in an urban academic family practice clinic on patient compliance to recommended dilated eye examination (REE). PATIENTS AND METHODS: Two hundred four patients with diabetes mellitis who were noncompliant to annual REE were screened for diabetic retinopathy using nDFP. The images were electronically transmitted to the retinal specialist to triage them for follow-up REE based on the photographic findings...
September 2011: Ophthalmic Surgery, Lasers & Imaging
https://read.qxmd.com/read/21686831/late-diagnosis-of-a-rare-disease
#17
JOURNAL ARTICLE
Noha Mohamed El Hossainy
Rare diseases may be misdiagnosed if laboratory investigations show a common diagnosis instead. This is the story of 24-year-old male patient misdiagnosed as a case of hereditary spherocytosis at the age of 10 years. He received regular blood transfusions. Thorough investigations revealed microcytic anaemia, with results for all hereditary and acquired causes of haemolytic anemia negative, iron overload in the liver, stunted growth, insulin-dependent diabetes mellitis, hypercellular bone marrow and marked depletion of its iron stores...
2009: BMJ Case Reports
https://read.qxmd.com/read/20554929/previous-gestational-diabetes-impairs-long-term-endothelial-function-in-a-mouse-model-of-complicated-pregnancy
#18
JOURNAL ARTICLE
Joanna L Stanley, Sowndramalingam Sankaralingam, Philip N Baker, Sandra T Davidge
Women who develop gestational diabetes mellitis (GDM) display endothelial dysfunction up to 1 yr after pregnancy, despite a return to normoglycemia. It is unknown whether this dysfunction was preexisting or whether GDM pregnancy leads to long-term endothelial dysfunction. A mouse model that spontaneously develops GDM (Lepr(db/+)) was used to determine whether the endothelial dysfunction that develops during GDM is evident in later life. Heterozygous and wild-type (WT) controls were allowed to litter once, then age to 9-10 mo, and were compared with virgin controls...
September 2010: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/20257332/effect-of-diabetes-mellitis-on-foetus
#19
JOURNAL ARTICLE
H BAHRY
No abstract text is available yet for this article.
April 1947: Journal
https://read.qxmd.com/read/17870551/-how-to-evaluate-the-cardiovascular-and-renal-risk-at-the-individual-level
#20
JOURNAL ARTICLE
Thierry Schaeverbeke, Eric Vicaut, Ariel Cohen, Philippe Ravaud
The cardiovascular impact of the non-steroidal anti-inflammatory drugs and the higher cardiovas-cular mortality during treatment of inflammatory rheumatism impose a rigorous evaluation of the cardiovascular risk of rheumatic patients. Large epidemiological studies have identified risk factors for cardiovascular diseases such as the age, male gender, family history (infarct, stroke), tobacco consumption, systolic arterial pressure, renal insufficiency, hypercholesterolemia, diabetes mellitis, sedentariness, obesity and "electric" ventricular hypertrophy...
September 2006: La Presse Médicale
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