Sho Horikoshi, Itaru Miura, Yuhei Suzuki, Yuri Kobayashi, Yoichiro Hirata, Masayuki Goto, Mizue Ichinose, Shinnosuke Yamamoto, Keiko Kanno-Nozakio, Kenya Watanabe, Hirooki Yabe
STUDY OBJECTIVES: We conducted a retrospective study to investigate the efficacy and safety of switching from other hypnotics, including benzodiazepines, Z-drugs (BZDs), suvorexant, ramelteon, mirtazapine, trazodone, and antipsychotics to lemborexant (LEB), a dual orexin receptor antagonist, for 3 months (3M). METHODS: Clinical data obtained from the medical records of 61 patients treated at the Horikoshi Psychosomatic Clinic between December 2020 and February 2022 were analyzed, including the Athens Insomnia Scale (AIS), Epworth Sleepiness Scale (ESS), and Perceived Deficits Questionnaire-5 (PDQ-5)...
May 30, 2023: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine