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outpatient chemotherapy

Danbee Kang, Im-Ryung Kim, Eun-Kyung Choi, Young Hyuck Im, Yeon Hee Park, Jin Seok Ahn, Jeong Eon Lee, Seok Jin Nam, Hae Kwang Lee, Ji-Hye Park, Dong-Youn Lee, Mario E Lacouture, Eliseo Guallar, Juhee Cho
BACKGROUND: Although chemotherapy-induced alopecia (CIA) is considered temporary, some patients report persistent alopecia several years after chemotherapy. There is, however, a paucity of long-term prospective data on the incidence and impact of permanent CIA (PCIA). The objective of our study was to estimate the long-term incidence of PCIA in a cohort of patients with breast cancer whose hair volume and density were measured prior to chemotherapy and who were followed for 3 years after chemotherapy...
August 17, 2018: Oncologist
Astha Koolwal Kapoor, Sushma Bhatnagar
Suicide risk is very high in the patients suffering from advanced cancer. Around 60% of patients with advanced cancer suffer from cancer related pain and this further accentuates the risk of psychiatric disorders as well as suicide. A fifty year old male who was a known case of carcinoma of floor of mouth, post chemotherapy and post radiotherapy came in the outpatient clinic with complains of throat pain which increased on swallowing. On further probing, it was revealed, that he consumed poison in the recent past while being agitated and upset with the severe throat pain...
July 2018: Indian Journal of Palliative Care
Yuko Sato, Mitsunori Miyashita, Kazuki Sato, Kenji Fujimori, Koichi Benjamin Ishikawa, Hiromasa Horiguchi, Kiyohide Fushimi, Chikashi Ishioka
Background: End-of-life (EOL) cancer care in Japanese acute care hospitals has not been well described. Methods: We aimed to assess the aggressiveness of EOL care and examine common treatments administered to cancer patients using a health administrative database. Subjects are adult cancer patients who died at acute care hospitals between April 2011 and March 2014. Data from the Japanese Diagnosis Procedure Combination database were analysed to measure the aggressiveness of care (chemotherapy, intensive care unit [ICU] admission and cardiopulmonary resuscitation [CPR]) and describe procedures and prescriptions administered in the last 14 and 30 days of life, disaggregated by hospital case volume: high, intermediate and low volumes...
August 13, 2018: Japanese Journal of Clinical Oncology
Takayuki Oishi, Kazuki Sato, Tatsuya Morita, Jennifer W Mack, Hideki Shimodaira, Masanobu Takahashi, Shin Takahashi, Akira Inoue, Yasuko Murakawa, Masanori Kawahara, Chikashi Ishioka, Mitsunori Miyashita
Background: Although reports have described the perceptions of curability among patients with unresectable/recurrent cancer and the quality of death and dying, the association between patients' perceptions and physicians' disclosures of incurability remained unexplored. This survey aimed to evaluate the association between patients' perceptions of curability and physicians' disclosures of incurability. Methods: In this cross-sectional, multicenter, observational study in Japan, we asked outpatients with unresectable/recurrent solid cancers about their perceptions of incurability...
August 9, 2018: Japanese Journal of Clinical Oncology
Florence Van Ryckeghem, Chloë Haverbeke, Wim Wynendaele, Guy Jerusalem, Luc Somers, Anke Van den Broeck, Sofie Vingerhoedt, Simon Van Belle
PURPOSE: To prevent febrile neutropenia (FN), European Organisation for Research and Treatment of Cancer (EORTC) guidelines recommend primary prophylaxis with granulocyte colony-stimulating factors (PPG) for patients at high risk (≥ 20%) of FN. In Belgium, the use of PPG is restricted by specific reimbursement criteria. The impact of these criteria on PPG use and adherence to guidelines is unknown. METHODS: This multicentre, cross-sectional, observational study aimed to describe PPG use by FN risk category in breast cancer patients who were scheduled to receive myelosuppressive chemotherapy in outpatient clinics in Belgium during a 2-week period between 13 October and 12 December 2014...
August 11, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Asaranti Kar, Bharat Satapathy, Kaumudee Pattnaik, Prafulla K Dash
Preoperative pathologic diagnosis of pelvic tumors is mandatory for proper management of patients like neoadjuvant chemotherapy and interval debulking. Currently there are many minimally invasive methods available which include fine-needle aspiration cytology (FNAC) and trucut biopsy, mostly complimentary to each other. FNAC is a cheap, rapid and sensitive method for diagnosis of pelvic tumors. It can be done as an outpatient procedure without complications. But with it, the tissue architecture cannot be seen...
July 2018: Journal of Cytology
Fernando Meton de Alencar Camara Vieira, Ana Paula Ornellas de Souza Victorino, Daniel de Iracema Gomes Cubero, Carlos Augusto de Mendonça Beato, Eimy Minowa, Guilherme Silva Julian, Diego Novick
PURPOSE: In Brazil, patients with gastric cancer have not been systematically followed-up and evaluated, thus data regarding patterns of care and outcomes are scarce or missing. The objective of this study was to evaluate patterns of care of advanced gastric cancer in standard practice in Brazil. METHODS: This was an observational, multicenter, retrospective study, which included patients with metastatic and/or unresectable gastric cancer (MGC) who underwent at least one line of treatment...
August 4, 2018: Journal of Gastrointestinal Cancer
Catherine Copley-Merriman, Kendall Stevinson, Frank Xiaoqing Liu, Jingshu Wang, Josephine Mauskopf, Evelina A Zimovetz, Bartosz Chmielowski
BACKGROUND: Treatments for advanced melanoma are associated with different adverse events (AEs), which may be costly to manage. This study aimed to evaluate direct costs associated with managing treatment-related AEs for advanced melanoma through a systematic literature review. METHODS: Systematic searches were conducted of the PubMed, Embase, Cochrane, BIOSIS, and EconLit medical literature databases to identify studies providing estimates of direct costs and health care resource utilization for the management of AEs of melanoma treatments, published between January 1, 2007, and February 23, 2017...
August 2018: Medicine (Baltimore)
Ann M Dose, Pamela J McCabe, Catherine A Krecke, Jeff A Sloan
Dignity therapy is a psychosocial intervention provided at the end of life to improve patient outcomes, but many persons cannot complete it because of health decline. Patients also reprioritize their life plans as death becomes imminent. As part of meeting standards to provide psychosocial palliative care simultaneously with cancer treatment, we provided a dignity therapy/life plan intervention to 18 patients with advanced pancreatic or lung cancer receiving cancer treatment. The study aim was to evaluate patient-reported outcomes of dignity therapy/life plan...
August 2018: Journal of Hospice and Palliative Nursing: JHPN
Paul C Nathan, Karen E Bremner, Ning Liu, Sumit Gupta, Mark L Greenberg, Mary L McBride, Murray D Krahn, Claire de Oliveira
Background: Adolescents with cancer can receive care in pediatric or adult institutions. Survival often differs by locus, but little is known about relative health care utilization and costs. We estimated these in a population-based cohort of adolescents. Methods: All Ontario adolescents (15.0-17.9 years) diagnosed with cancer between 1995 and 2010 were identified from provincial cancer registries. We compared health care resource utilization (hospitalizations, emergency department visits, same-day surgeries, outpatient chemotherapy, radiation, diagnostic/laboratory tests, physician services, home care) and costs (2012 Canadian dollars) during four discrete care phases-prediagnosis (60 days), initial (360 days), continuing (variable), and terminal (360 days)-between adolescents treated in pediatric vs adult institutions, for the whole cohort and within seven diagnostic categories...
July 19, 2018: Journal of the National Cancer Institute
Michael S Broder, Beilei Cai, Eunice Chang, Tingjian Yan, Al B Benson Iii
OBJECTIVE: To assess first-line treatment adherence, healthcare resource utilization, and costs in lung NET patients initiating pharmacologic treatments. METHODS: In two US claims databases, patients aged ≥18 years with ≥1 inpatient or ≥2 outpatient lung NET claims within 12 months were identified. The first claim for pharmacologic treatments (e.g. somatostatin analogs [SSAs], cytotoxic chemotherapy [CC], targeted therapy [TT]) following diagnosis, between July 1, 2009-December 31, 2014, was defined as the index date...
August 10, 2018: Current Medical Research and Opinion
Yoshihisa Ishiura, Yasutaka Shiba, Yasushi Terasaki, Seiko Yoneyama, Kazutoshi Yamada, Yoshinobu Hinoue, Yoichi Ishida, Masataka Segawa, Yoshinori Doki, Kazuo Kasahara, Masaki Fujimura, Shinji Nakao, Takeshi Tamaki, Toshiki Shimizu, Shosaku Nomura
An increasing number of patients with lung cancer are undergoing outpatient chemotherapy, and thus, it is very important to maintain the quality of life(QOL)of these patients. Ninjin-Youei-To(TJ-108), a Japanese traditional medicine, has been reported to improve the QOL of patients with advanced cancer. However, the effect of TJ-108 in patients with lung cancer undergoing outpatient chemotherapy is unknown. Therefore, we conducted this study. To investigate factors influencing the QOL of these patients, we administered a QOL questionnaire,"The QOL Questionnaire for Cancer Patients Treated with Anticancer Drugs"(QOL-ACD)to 15 patients with non-small cell lung cancer...
July 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Semiha Akin, Canan Kas Guner
To explore the relationship between fatigue and self-efficacy, and quality of life (QoL) during chemotherapy of patients with breast, lung or gastrointestinal cancers. This study is a descriptive-correlational research. The study population comprised of patients with breast, lung and gastrointestinal cancer treated at the outpatient chemotherapy unit. Patients' self-efficacy and QoL were assessed using Functional Assessment of Chronic Illness Therapy-Fatigue scale and Strategies Used by Patients to Promote Health scale...
July 24, 2018: European Journal of Cancer Care
Emily M Webster, William M Burke, Hannah M Ware, Bayley A Jones, Reena Vattakalam, Ana I Tergas, Jason D Wright, June Y Hou
OBJECTIVE: Patient reported outcomes (PRO) relating to treatment toxicities have been demonstrated to reliably evaluate adverse events in clinical trials. We assessed the user satisfaction of implementing a focused PRO questionnaire for patients with gynecologic cancers undergoing chemotherapy. METHODS: Patients with gynecologic cancers undergoing chemotherapy were prospectively identified after IRB approval from April 2017 to August 2017. We administered a 24-symptom questionnaire, adapted from the validated PRO version of the Common Terminology Criteria for Adverse Event, to enrolled participants at the beginning of two outpatient visits...
July 20, 2018: Gynecologic Oncology
Eliza A Hawkes, Zoe Loh, Ortis Estacio, Geoff Chong, Francis J Ha, Michael Gilbertson, Andrew Grigg
BACKGROUND: Patients with aggressive lymphoma achieving complete remission (CR) after first-line combination chemotherapy undergo regular surveillance to detect relapse. Current international guidelines recommend routine follow-up blood tests in this context, but evidence supporting this practice is limited. METHODS: We conducted a multi-centre retrospective analysis of all patients diagnosed with aggressive lymphoma treated with curative-intent chemotherapy who achieved CR for at least 3 months between 2000 and 2015...
July 23, 2018: British Journal of Cancer
Masaya Yokoyama, Kazuma Yamazaki, Masaaki Kodama, Satoru Kondo, Atsushi Yoshida, Yuzo Miyahara
A 50-year old male patient chose to have elective surgery for obstructive rectal cancer. Before undergoing surgery, he had a self-expandable metallic stent (SEMS) placed to relieve a colonic obstruction. He was discharged from our hospital after the elective surgery without surgical complications. In our outpatient clinic, he was prescribed UFT/LV for adjuvant chemotherapy. Eight months after surgery, he came back to the hospital complaining of abdominal distension, abdominal pain and constipation. A diagnosis of local recurrence of rectal cancer, peritoneal metastasis and metastatic liver cancer was confirmed...
May 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Akira Tokutome, Ryoo Taniguchi, Kenta Maeda, Yasuhiro Saito, Takahiro Ishii, Seiichi Minami, Yuji Wano, Tomoyuki Ota, Hiroshi Saitoh, Kiyotaka Takeda
As the number of patients undergoing outpatient chemotherapy has increased, there is concern that cancer patients' family members are unknowingly exposed to antineoplastic agents at home through cancer patients' excrement or other secreted materials. In this study, we created a pamphlet that introduces several methods to prevent exposure to antineoplastic agents at home and conducted a questionnaire survey to assess the usefulness of the pamphlet. The results indicated that more than 90% of patients believed that the pamphlet was "useful" or "very useful" for ensuring safety with respect to antineoplastic agents at home...
May 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Koichi Kawabuchi, Keiko Kajitani
Healthcare economics concerns with the way in which to distribute and allocate scarce resources that result in maximized outcome. When the expenditure on cancer medicine was examined using the macro data open to the public, it was found to have increased in parallel with the National Medical Care Expenditure. More specifically, the growth rates of the two showed a similar trend in the five years from 2011 to 2015. However, when looked more closely by excluding the patient share and separating the care settings, the result was different...
May 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Fay Wright, Laura B Dunn, Steven M Paul, Yvette P Conley, Jon D Levine, Marilyn J Hammer, Bruce A Cooper, Christine Miaskowski, Kord M Kober
BACKGROUND: Morning fatigue is a distinct symptom experienced during chemotherapy that demonstrates significant interindividual variability. OBJECTIVES: The aims of this study were to identify subgroups with distinct morning fatigue profiles and evaluate how these subgroups differed by demographic, clinical, and symptom characteristics. METHODS: Outpatients (N = 1332) with breast, gastrointestinal, gynecological, or lung cancer completed questionnaires 6 times over 2 cycles of chemotherapy...
July 17, 2018: Cancer Nursing
Yamini Kalidindi, Jeah Jung, Roger Feldman
OBJECTIVES: To compare Medicare spending on provider-administered chemotherapy in hospital outpatient departments (HOPDs) and physician offices after controlling for cancer type. STUDY DESIGN: Secondary data analysis. METHODS: We used 2010-2013 claims data for a random sample of Medicare fee-for-service beneficiaries who had cancer and received chemotherapy services either in physician offices or in HOPDs. We constructed 2 spending measures: (1) spending on chemotherapy drugs and (2) spending on chemotherapy administration...
July 2018: American Journal of Managed Care
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