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https://www.readbyqxmd.com/read/30341960/impact-of-ige-sensitization-and-rhinitis-on-inflammatory-biomarkers-and-lung-function-in-adolescents-with-and-without-asthma
#1
Jenny Hallberg, Natalia Ballardini, Catarina Almqvist, Marit Westman, Marianne van Hage, Gunnar Lilja, Anna Bergström, Inger Kull, Erik Melén
BACKGROUND: Both allergic and non-allergic rhinitis are associated with worse asthma control. However, it is unclear how IgE sensitization and/or rhinitis are associated to lung function. We therefore evaluated the effect of rhinitis and sensitization on lung function, including the periphery of the airway system, and inflammatory biomarkers in individuals with and without asthma. METHODS: Participants in the BAMSE longitudinal birth cohort study underwent measures of spirometry, impulse oscillometry and FeNO at age 16 years...
October 20, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/30341118/assessing-the-chronic-respiratory-health-risk-associated-with-inhalation-exposure-to-powdered-toner-for-printing-in-actual-working-conditions-a-cohort-study-on-occupationally-exposed-workers-over-10-years
#2
Toshio Nakadate, Yuko Yamano, Takenori Yamauchi, Shigeko Okubo, Daichi Nagashima
BACKGROUND: Little epidemiological evidence exists regarding the chronic respiratory effects of inhaled powdered toner exposure in humans, although several case reports have suggested the existence of lung disorders that might be related to exposure to toner dust. OBJECTIVE: We aimed to estimate the chronic health risk to humans associated with routine toner dust exposure in copier industry workers under current actual work conditions. DESIGN: A prospective observational cohort study of occupational population...
October 18, 2018: BMJ Open
https://www.readbyqxmd.com/read/30340648/effectiveness-implementation-of-copd-case-finding-and-self-management-action-plans-in-low-and-middle-income-countries-global-excellence-in-copd-outcomes-geco-study-protocol
#3
Trishul Siddharthan, Suzanne L Pollard, Shumonta A Quaderi, Andrew J Mirelman, Maria Kathia Cárdenas, Bruce Kirenga, Natalie A Rykiel, J Jaime Miranda, Laxman Shrestha, Ram K Chandyo, Adithya Cattamanchi, Susan Michie, Julie Barber, William Checkley, John R Hurst
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the end result of a susceptible individual being exposed to sufficiently deleterious environmental stimuli. More than 90% of COPD-related deaths occur in low- and middle-income countries (LMICs). LMICs face unique challenges in managing COPD; for example, deficient primary care systems present challenges for proper diagnosis and management. Formal diagnosis of COPD requires quality-assured spirometry, which is often limited to urban health centres...
October 19, 2018: Trials
https://www.readbyqxmd.com/read/30340565/adherence-to-inhaled-therapy-and-its-impact-on-chronic-obstructive-pulmonary-disease-copd
#4
Magdalena Humenberger, Andreas Horner, Anna Labek, Bernhard Kaiser, Rupert Frechinger, Constanze Brock, Petra Lichtenberger, Bernd Lamprecht
BACKGROUND: COPD is a treatable disease with increasing prevalence worldwide. Treatment aims to stop disease progression, to improve quality of life, and to reduce exacerbations. We aimed to evaluate the association of the stage of COPD on adherence to inhaled therapy and the relationship between adherence and COPD exacerbations. METHODS: A retrospective analysis of patients hospitalized for acute exacerbation of COPD in a tertiary care hospital in Upper Austria and discharged with a guideline conform inhaled therapy was performed...
October 19, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/30339770/remotely-monitored-therapy-and-nitric-oxide-suppression-identifies-non-adherence-in-severe-asthma
#5
Liam G Heaney, John Busby, Peter Bradding, Rekha Chaudhuri, Adel H Mansur, Robert Niven, Ian D Pavord, John T Lindsay, Richard W Costello
Rationale Poor adherence is common in difficult-to-control asthma. Distinguishing patients with difficult-to-control asthma who respond to inhaled corticosteroids (ICS) from refractory asthma is an important clinical challenge. Objectives Suppression of fractional exhaled nitric oxide (FeNO) with directly observed ICS therapy over 7 days can identify non-adherence to ICS treatment in difficult-to-control asthma. We examined the feasibility and utility of FeNO suppression testing in routine clinical care within UK severe asthma centres using remote monitoring technologies...
October 19, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/30339699/lung-function-in-adults-born-preterm
#6
Pieta Näsänen-Gilmore, Marika Sipola-Leppänen, Marjaana Tikanmäki, Hanna-Maria Matinolli, Johan G Eriksson, Marjo-Riitta Järvelin, Marja Vääräsmäki, Petteri Hovi, Eero Kajantie
Very preterm birth, before the gestational age (GA) of 32 weeks, increases the risk of obstructed airflow in adulthood. We examined whether all preterm births (GA<37 weeks) are associated with poorer adult lung function and whether any associations are explained by maternal, early life/neonatal, or current life factors. Participants of the ESTER Preterm Birth Study, born between 1985 and 1989 (during the pre-surfactant era), at the age of 23 years participated in a clinical study in which they performed spirometry and provided detailed medical history...
2018: PloS One
https://www.readbyqxmd.com/read/30339304/asthma-related-outcomes-associated-with-indoor-air-pollutants-among-schoolchildren-from-four-informal-settlements-in-two-municipalities-in-the-western-cape-province-of-south-africa
#7
Toyib Olaniyan, Mohamed Aqiel Dalvie, Martin Röösli, Rajen Naidoo, Nino Künzil, Kees de Hoogh, Bhawoodien Parker, Joy Leaner, Mohamed Jeebhay
The health impact of indoor air pollution in informal settlement households has not been extensively studied in South Africa. This cross-sectional study investigated the association between asthma and common indoor exposures among schoolchildren from four informal settlements located in two municipalities in the Western Cape Province. A total of 590 children, aged 9 - 11 years, were recruited. The International Study of Asthma and Allergies in Children (ISAAC) questionnaire, was administered to caregivers. Pulmonary function assessment included spirometry and fractional-exhaled nitric oxide (FeNO)...
October 19, 2018: Indoor Air
https://www.readbyqxmd.com/read/30338578/prenatal-high-molecular-weight-phthalates-and-bisphenol-a-and-childhood-respiratory-and-allergic-outcomes
#8
Kimberly Berger, Brenda Eskenazi, John Balmes, Katie Kogut, Nina Holland, Antonia M Calafat, Kim G Harley
BACKGROUND: Asthma and allergy prevalence is increasing in United States children. In utero exposure to chemicals used in personal care products and plastics may contribute to increase in these diseases. METHODS: We quantified urinary concentrations of eight phthalate metabolites and bisphenol A in mothers twice during pregnancy in 1999-2000 in Salinas, California. We assessed probable asthma, aeroallergies, eczema, and spirometry in their age 7 children, and measured T helper 1 and T helper 2 cells in blood at ages 2, 5, and 7 (N=392)...
October 18, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/30336970/longitudinal-pulmonary-function-testing-outcome-measures-in-duchenne-muscular-dystrophy-long-term-natural-history-with-and-without-glucocorticoids
#9
Craig M McDonald, Heather Gordish-Dressman, Erik K Henricson, Tina Duong, Nanette C Joyce, Sanjay Jhawar, Mika Leinonen, Fengming Hsu, Anne M Connolly, Avital Cnaan, Richard T Abresch
We describe changes in pulmonary function measures across time in Duchenne muscular dystrophy patients treated with glucocorticoids (GCs) > 1 year compared to GC naïve patients in the Cooperative International Research Group Duchenne Natural History Study, a multicenter prospective cohort study. 397 participants underwent 2799 pulmonary function assessments over a period up to 10 years. Fifty-three GC naïve participants (< 1 month exposure) were compared to 322 subjects with > 1 year cumulative GC treatment...
August 29, 2018: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/30335595/occupational-exposure-to-trichloramine-and-trihalomethanes-adverse-health-effects-among-personnel-in-habilitation-and-rehabilitation-swimming-pools
#10
Jessica Westerlund, Ing-Liss Bryngelsson, Håkan Löfstedt, Kåre Eriksson, Håkan Westberg, Pål Graff
Personnel in swimming pool facilities typically experience ocular, nasal, and respiratory symptoms due to water chlorination and consequent exposure to disinfection by-products in the air. The aim of the study was to investigate exposure to trichloramine and trihalomethanes (chloroform, bromodichloromethane, dibromochloromethane, and bromoform) from the perspective of adverse health effects on the personnel at Swedish habilitation and rehabilitation swimming pools. The study included ten habilitation and rehabilitation swimming pool facilities in nine Swedish cities...
October 18, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/30329072/health-hazards-and-risks-for-musculoskeletal-problems-among-child-labourers-in-the-brickfield-sector-of-west-bengal-india
#11
Banibrata Das
Aims: The purpose of this study was to describe the health hazards among child labourers in brickfields, and to assess occupational health problems, together with physiological and respiratory stress, compared with child control subjects. Methods: A cross-sectional study was conducted on 112 child brickfield workers and 120 control subjects, and a modified Nordic Questionnaire was applied to assess the discomfort felt among both groups of workers. Physiological assessment of the workload was carried out by the measurement of heart rate, blood pressure and spirometry of the workers...
October 17, 2018: International Health
https://www.readbyqxmd.com/read/30328928/spirometry-in-patients-screened-for-coronary-artery-disease-is-it-useful
#12
Frederico Leon Arrabal Fernandes, Regina Maria Carvalho-Pinto, Rafael Stelmach, João Marcos Salge, Carlos Eduardo Rochitte, Eliane Cardoso Dos Santos Souza, Janaina Danielle Pessi, Alberto Cukier
OBJECTIVE: To determine the prevalence of spirometric abnormalities in patients screened for coronary artery disease (CAD) and the risk factors for lung function impairment. METHODS: Patients referred for cardiac CT underwent spirometry and were subsequently divided into two groups, namely normal lung function and abnormal lung function. The prevalence of spirometric abnormalities was calculated for the following subgroups of patients: smokers, patients with metabolic syndrome, elderly patients, and patients with obstructive coronary lesions...
July 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/30328036/prevalence-of-chronic-obstructive-pulmonary-disease-copd-among-congolese-cement-workers-exposed-to-cement-dust-in-kongo-central-province
#13
Etongola Papy Mbelambela, Masamitsu Eitoku, Sifa Marie Joelle Muchanga, Antonio F Villanueva, Ryoji Hirota, Tiffany Yuka Pulphus, Gedikondele Jérôme Sokolo, Kahoko Yasumitsu-Lovell, Kaori Komori, Narufumi Suganuma
Chronic exposure to cement dust may induce adverse health effects, including a significant decrease in lung function. The study investigated whether the prevalence of COPD and respiratory symptoms was associated with working at different tasks exposed to varying levels of cement dust. The cross-sectional study was carried out among 223 exposed and 156 less exposed workers from two cement factories from November 20 to December 15, 2016 in DRC. Workers completed a questionnaire and spirometry was performed. Multivariate analysis was performed to evaluate the association between occupation exposed to cement dust, COPD, and respiratory symptoms, after adjustment for confounders...
October 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/30327337/exercise-induced-oxygen-desaturation-as-a-predictive-factor-for-longitudinal-decline-in-6-minute-walk-distance-in-subjects-with-copd
#14
Shogo Misu, Masahiro Kaneko, Hideki Sakai, Yutaro Oki, Yukari Fujimoto, Akira Ishikawa, Rei Ono
BACKGROUND: There are limited longitudinal studies reporting predictive factors for decline in 6-min walk distance (6MWD) in patients with COPD. While previous studies have confirmed the association between air-flow limitation and decline in 6MWD, other factors have not been clarified. The objective of this study was to investigate whether exercise-induced oxygen desaturation (EID) could be a predictive factor for decline in 6MWD in patients with COPD. The interactive effect of air-flow limitation on the association between EID and decline in 6MWD was also investigated...
October 16, 2018: Respiratory Care
https://www.readbyqxmd.com/read/30327288/design-rationale-and-performance-evaluation-of-the-wavelet-health-wristband-benchtop-validation-of-a-wrist-worn-physiological-signal-recorder
#15
Onur Dur, Colleen Rhoades, Man Suen Ng, Ragwa Elsayed, Reinier van Mourik, Maulik D Majmudar
BACKGROUND: Wearable and connected health devices along with the recent advances in mobile and cloud computing provide a continuous, convenient-to-patient, and scalable way to collect personal health data remotely. The Wavelet Health platform and the Wavelet wristband have been developed to capture multiple physiological signals and to derive biometrics from these signals, including resting heart rate (HR), heart rate variability (HRV), and respiration rate (RR). OBJECTIVE: This study aimed to evaluate the accuracy of the biometric estimates and signal quality of the wristband...
October 16, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/30325109/clinical-course-of-chronic-suppurative-lung-disease-and-bronchiectasis-in-alaska-native-children
#16
BreAnna Kinghorn, Rosalyn Singleton, Gabrielle B McCallum, Lisa Bulkow, Keith Grimwood, Leslie Hermann, Anne B Chang, Gregory Redding
INTRODUCTION: Alaska Native (AN) children from the Yukon Kuskokwim (YK) Delta region have high rates of chronic suppurative lung disease (CSLD), including bronchiectasis. We characterized the clinical progress of an AN adolescent cohort with CSLD/bronchiectasis, and estimated bronchiectasis prevalence trends in this region. METHODS: The original cohort comprised 41 AN children (originally aged 0.5-8 years) with CSLD/bronchiectasis, recruited between 2005 and 2008, with follow-up in 2015-2016...
October 16, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/30323577/validity-of-icd9-cm-codes-to-diagnose-chronic-obstructive-pulmonary-disease-from-national-health-insurance-claim-data-in-taiwan
#17
Te-Wei Ho, Sheng-Yuan Ruan, Chun-Ta Huang, Yi-Ju Tsai, Feipei Lai, Chong-Jen Yu
Purpose: Claim data from Taiwan's National Health Insurance (NHI) database have previously been utilized in the study of COPD. However, there are limited data on the positive predictive value of claim data for COPD diagnosis. Therefore, this study aimed to characterize and validate the COPD cohort identified from the NHI research database. Methods: This cross-sectional study compared records from claim data with those from a medical center. From 2007 to 2014, a COPD cohort was constructed from claim data using ICD9-CM codes for COPD...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/30323179/parasternal-intercostal-muscle-ultrasound-in-chronic-obstructive-pulmonary-disease-correlates-with-spirometric-severity
#18
Peter Wallbridge, Selina M Parry, Sourav Das, Candice Law, Gary Hammerschlag, Louis Irving, Mark Hew, Daniel Steinfort
In chronic obstructive pulmonary disease (COPD), loss of computed tomography (CT)-measured intercostal mass correlates with spirometric severity. Intercostal muscle ultrasound offers a repeatable and radiation-free alternative, however requires validation. We aimed to determine the reliability of parasternal intercostal muscle ultrasound, and the concurrent validity of parasternal ultrasound with clinicometric parameters. Twenty stable COPD patients underwent ultrasound measurement of thickness and echogenicity of 2nd and 3rd parasternal intercostal muscles, dominant pectoralis major and quadriceps, and diaphragm thickness; spirometry; and chest CT...
October 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30322444/causes-of-dyspnea-after-cardiac-surgery
#19
Ahmet Bolukçu, Sami İlhan, Ahmet Can Topçu, Rafet Günay, İlyas Kayacıoğlu
OBJECTIVES: Postoperative dyspnea is common after cardiac surgery, even in low-risk patients. Cardiac surgeons and anesthesiologists are familiar with patients suffering from dyspnea in the early postoperative period, but in some cases, conventional treatment strategies may be ineffective, and a consultation with a pulmonologist may be required. The aim of this study is to investigate the causes of dyspnea after cardiac surgery in this particular patient group. MATERIALS AND METHODS: The hospital database was searched for non-emergency cardiac surgery for the period January 2014-October 2015...
September 13, 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/30322439/pulmonary-rehabilitation-reduces-emergency-admission-and-hospitalization-rates-of-patients-with-chronic-respiratory-diseases
#20
İpek Özmen, Elif Yıldırım, Murat Öztürk, Birsen Ocaklı, Reyhan Yıldız, Rüya Aydın, Meral Karakış, Özgür Yılmaz, Emine Aksoy
OBJECTIVES: Chronic respiratory diseases exert a global health burden with high health care costs, morbidity, and mortality. The aim of the present study was to investigate the effect of pulmonary rehabilitation (PR) on emergency admission and hospitalization rates of patients with chronic respiratory disease. MATERIALS AND METHODS: In this retrospective cohort study, hospitalization rates and emergency admissions of patients before (December 2014-December 2015) and after PR (January 2015-December 2016) were investigated...
September 13, 2018: Turkish Thoracic Journal
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