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spirometer OR spirometry

Katharina Schütz, Diana Alecsandru, Bodo Grimbacher, Jamanda Haddock, Annemarie Bruining, Gertjan Driessen, Esther de Vries, Peter M van Hagen, Ieneke Hartmann, Francesco Fraioli, Cinzia Milito, Milica Mitrevski, Isabella Quinti, Goffredo Serra, Peter Kelleher, Michael Loebinger, Jiri Litzman, Vera Postranecka, Vojtech Thon, Judith Babar, Alison M Condliffe, Andrew Exley, Dinakantha Kumararatne, Nick Screaton, Alison Jones, Maria P Bondioni, Vassilios Lougaris, Alessandro Plebani, Annarosa Soresina, Cesare Sirignano, Giuseppe Spadaro, Nermeen Galal, Luis I Gonzalez-Granado, Sabine Dettmer, Robert Stirling, Helen Chapel, Mary Lucas, Smita Patel, Claire-Michele Farber, Isabelle Meyts, Arpan K Banerjee, Scott Hackett, John R Hurst, Klaus Warnatz, Benjamin Gathmann, Ulrich Baumann
Studies of chest computed tomography (CT) in patients with primary antibody deficiency syndromes (ADS) suggest a broad range of bronchial pathology. However, there are as yet no multicentre studies to assess the variety of bronchial pathology in this patient group. One of the underlying reasons is the lack of a consensus methodology, a prerequisite to jointly document chest CT findings. We aimed to establish an international platform for the evaluation of bronchial pathology as assessed by chest CT and to describe the range of bronchial pathologies in patients with antibody deficiency...
December 13, 2018: Journal of Clinical Immunology
Jann Mortensen, Ronan M G Berg
Ventilation-perfusion scintigraphy is a functional imaging biomarker that has the potential of captivating the heterogeneity of chronic obstructive pulmonary disease (COPD). It specifically images the distribution of ventilation and perfusion within the lungs, which is a critical pathophysiological component of COPD. The extent of ventilation defects and ventilation inhomogeneity, as well as the ventilation-perfusion ratio distribution thus correlate with severity of disease. Furthermore, specific scintigraphic patterns, such as the "stripe sign" may detect centrilobular emphysematous lesions with a higher sensitivity than other imaging techniques...
January 2019: Seminars in Nuclear Medicine
Henrik Watz, Kay Tetzlaff, Helgo Magnussen, Achim Mueller, Roberto Rodriguez-Roisin, Emiel F M Wouters, Claus Vogelmeier, Peter M A Calverley
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with loss of lung function and poor outcomes for patients. However, there are limited data on the time course of changes in forced expiratory volume in 1 s (FEV1 ) preceding the first reported symptom and after the start of an exacerbation. METHODS: WISDOM was a multinational, randomized, double-blind, active-controlled, 52-week study in patients with severe-to-very severe COPD...
December 13, 2018: Respiratory Research
Alexandra Lenoir, Jean-William Fitting, Pedro-Manuel Marques-Vidal, Peter Vollenweider, Laurent P Nicod
BACKGROUND: Reduced lung function predicts increased mortality, but its prevalence may vary depending on definition considered, use of bronchodilation and applied reference values. We aimed to assess lung function abnormalities in Lausanne, Switzerland, and their association with clinical history. METHODS: In a general population sample, spirometry was performed and bronchodilation applied if the ratio forced expiratory volume in 1 s (FEV1) / forced vital capacity (FVC) or the FVC was below the lower limit of normal (LLN) according to Global Lung Function Initiative 2012 references...
December 13, 2018: Respiratory Research
Antonello D'Andrea, Anna Agnese Stanziola, Rajan Saggar, Rajeev Saggar, Simona Sperlongano, Marianna Conte, Michele D'Alto, Francesco Ferrara, Luna Gargani, Patrizio Lancellotti, Eduardo Bossone
BACKGROUND: The most important determinant of long term survival in idiopathic pulmonary fibrosis (IPF) patients is the adaptation of the right ventricle (RV) to the increased pulmonary vascular resistance. Our aim was to explore RV contractile reserve during stress echocardiography (SE) in early stage IPF. METHODS: 50 early stage IPF patients and 50 healthy controls underwent rest and SE, including RV 2-dimensional Speckle Tracking Echocardiography (2DSTE). At peak exertion blood gas analysis and spirometry were also assessed...
December 10, 2018: Chest
Mariarita Stendardo, Melissa Bonci, Valeria Casillo, Rossella Miglio, Giulia Giovannini, Marco Nardini, Gianluca Campo, Alessandro Fucili, Piera Boschetto
OBJECTIVES: Return to work after acute myocardial infarction (AMI), a leading cause of death globally, is a multidimensional process influenced by clinical, psychological, social and occupational factors, the single impact of which, however, is still not well defined. The objective of this study was to investigate these 4 factors on return to work (RTW) within 365 days after AMI in a homogeneous cohort of patients who had undergone an urgent coronary angioplasty. PARTICIPANTS: We studied 102 patients, in employment at the time of AMI (88...
2018: PloS One
Hyekyun Rhee, Tanzy Love, Donald Harrington
Background: Sputum neutrophils are associated with severe asthma, poor pulmonary function and high body mass index (BMI) in adult patients. However, little is known about the relationships between blood neutrophils, BMI and asthma severity in pediatric patients. This brief report is to assess the predictive value of blood neutrophils for asthma severity, BMI and pulmonary function in adolescents with asthma. Methods: The study included 166 adolescents with physician diagnosed asthma for at least 1 year...
2018: JSM allergy and asthma
Ali Cevat Kutluk, Hasan Akin, Altan Ceritoglu, Celalettin Ibrahim Kocaturk, Salih Bilen, Yasar Sonmezoglu, Kemal Karapinar
PURPOSE: Lung cancer is one of the major sources of mortality in the elderly. This study was undertaken to assess the early and long-term results of surgical resection in patients older than 70 years of age by comparing the results of patients aged 70-79 years (group 1) with patients older than 80 years of age (group 2). METHODS: Data on patient age, gender, spirometry values, side, size, histology and stage of the tumor, surgical procedures, postoperative complications, Charlson comorbidity scores (CCS), and survival were collected...
December 11, 2018: Annals of Thoracic and Cardiovascular Surgery
I Rodríguez Clérigo, I Nieto Rojas, R Mota Santana, M J Abarca López, R Orueta Sánchez, F J Alonso Moreno, A Segura Fragoso
OBJECTIVE: To determine whether the baseline parameters of forced spirometry can influence the positivity of the bronchodilation test (BDT), and whether this could have an influence in future positivity criteria. MATERIAL AND METHODS: A descriptive, cross-sectional study was conducted in a Primary Care setting. It included all patients referred by their family doctor to perform a forced spirometry test due to smoking, respiratory symptoms, or follow-up of respiratory diseases, between the months of June 2015 and February 2017...
December 9, 2018: Semergen
Robert W V Flynn, Thomas M MacDonald, James D Chalmers, Stuart Schembri
BACKGROUND: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) severity stage classifies Chronic Obstructive Pulmonary Disease (COPD) into groups based on symptoms, exacerbations and forced expiratory volume in one second (FEV1 ). This allows patients to change to less severe COPD stages, a novel aspect of assessment not previously evaluated. We aimed to investigate the association between temporal changes in GOLD severity stage and outcomes in COPD patients. METHODS: This was a record-linkage study using patients registered with a Scottish regional COPD network 2000-2015...
December 12, 2018: Respiratory Research
Rodrigo Pereira de Souza, Márcio Vinícius Fagundes Donadio, João Paulo Heinzmann-Filho, Rafael Reimann Baptista, Leonardo Araújo Pinto, Matias Epifanio, Paulo José Cauduro Marostica
OBJECTIVE: To compare muscle thickness and subcutaneous fat in cystic fibrosis (CF) patients and healthy controls using ultrasonography (US), and to correlate US findings with nutritional, clinical and functional variables. METHODS: Patients aged 6 to 18 years old with a diagnosis of CF and healthy controls were included. Participants underwent anthropometric measurements, an ultrasonographic evaluation of muscle thickness and subcutaneous fat in the triceps, quadriceps, and gastrocnemius regions, and skinfold thickness measurements...
October 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Mekuriaw Mesfin Birhan, Yekoye Abebe
Background: Hypertension imposes stresses on many organs like heart and kidney. However, studies that show the effect of hypertension on the lungs are limited. Objective: To assess pulmonary function status of hypertensive patients aged 30-64 years at Zewditu Memorial Hospital, 2017. Methods: Hospital based comparative cross-sectional study was conducted on 61 hypertensive patients (cases) and 61 nonhypertensive clients (controls) aged 30-64 years...
2018: International Journal of Hypertension
Nguyen Truong Giang, Nguyen Van Nam, Nguyen Ngoc Trung, Le Viet Anh, Nguyen Manh Cuong, Ngo Van Dinh, Dinh Cong Pho, Phillip Geiger, Nguyen Trung Kien
Background: Paravertebral block has been proven to be an efficient method to provide post-thoracotomy pain management. This study aimed to compare patient-controlled paravertebral analgesia (PCPA) and intravenous patient-controlled analgesia (IVPCA) in terms of analgesic efficiency, respiratory function, and adverse effects after video-assisted thoracoscopic surgery (VATS) lobectomy. Patients and methods: The prospective randomized trial study was carried out on 60 patients who underwent VATS lobectomy (randomly allocated 30 patients in each group)...
2018: Local and Regional Anesthesia
Eugenia Quiros-Roldan, Maria Chiara Pezzoli, Marialma Berlendis, Elena Raffetti, Alice Ferraresi, Martina Properzi, Paola Rodari, Francesco Castelli
BACKGROUND: COPD screening guidelines in patients with HIV are lacking, and data about its under-diagnosis are still limited. This study aimed to determinate the feasibility of a case-finding program and the prevalence of COPD under-diagnosis in a large cohort of HIV-infected subjects. METHODS: All out-patients attending their routine visit for HIV monitoring at Spedali Civili General Hospital in Brescia, Italy, from February 2015 to January 2016, were enrolled...
December 11, 2018: Respiratory Care
In Suk Sol, Yoon Hee Kim, SooYeon Kim, Jong Deok Kim, Sun Ha Choi, Kyung Won Kim, Myung Hyun Sohn
BACKGROUND: Impulse oscillometry (IOS) measures respiratory resistance and reactance during tidal breaths and is a convenient tool for evaluation of lung function. Respiratory resistance and reactance can be measured separately during inspiration and expiration (inspiratory-expiratory analysis). OBJECTIVE: We investigated the differences in inspiratory-expiratory measurements obtained using IOS between children with and without asthma. METHODS: We analyzed 819 subjects aged 4-18 years, including asthmatic children (n = 600) and controls (n = 219)...
December 10, 2018: Pediatric Pulmonology
B Krishnamoorthy, W R Critchley, S Y Soon, R Birla, Z Begum, J Nair, N Devan, Ram Mohan, James Fildes, J Morris, C Fullwood, P Krysiak, I Malagon, R Shah
BACKGROUND: Thoracotomy is a common surgical procedure performed worldwide for lung disease. Despite major advances in analgesia, patients still experience severe shoulder, central back and surgical incision site pain in the postoperative period. This study aimed to assess whether intra-operative phrenic nerve infiltration reduces the incidence of postoperative pain and improves peak flow volume measurements during incentive spirometry. METHODS: 90 patients undergoing open lobectomy were randomly assigned to have phrenic nerve infiltration (n=46) or not (n=44)...
December 7, 2018: Seminars in Thoracic and Cardiovascular Surgery
Armando Almeida-Junior, Fernando Augusto Lima Marson, Celize Cruz Bresciani Almeida, Maria Ângela Gonçalves Oliveira Ribeiro, Ilma Aparecida Paschoal, Marcos Mello Moreira, José Dirceu Ribeiro
OBJECTIVE: To compare the values of the markers for volumetric capnography and spirometry and their ability to classify children and adolescents with asthma, cystic fibrosis (CF), and healthy controls. METHODS: This was a cross-sectional study that included 103 patients with controlled persistent allergic asthma, 53 with CF and a healthy control group with 40 volunteers (aged 6-15 years), of both sexes. The individuals underwent volumetric capnography and spirometry...
December 6, 2018: Jornal de Pediatria
Raquel Guimarães-Costa, Thomas Similowski, Isabelle Rivals, Capucine Morélot-Panzini, Marie-Cécile Nierat, Mai Thao Bui, David Akbar, Christian Straus, Norma Beatriz Romero, Patrick Pierre Michel, Fabrice Menegaux, François Salachas, Jésus Gonzalez-Bermejo, Gaëlle Bruneteau
Amyotrophic lateral sclerosis (ALS) patients show progressive respiratory muscle weakness leading to death from respiratory failure. However, there are no data on diaphragm histological changes in ALS patients and how they correlate with routine respiratory measurements.We collected 39 diaphragm biopsies concomitantly with laparoscopic insertion of intradiaphragmatic electrodes during a randomised controlled trial evaluating early diaphragm pacing in ALS (NCT01583088). Myofibre type, size, and distribution were evaluated by immunofluorescence microscopy and correlated with spirometry, respiratory muscle strength, and phrenic nerve conduction parameters...
December 5, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Carolina Bonfanti Mesquita, Caroline Knaut, Laura Miranda de Oliveira Caram, Renata Ferrari, Silmeia Garcia Zanati Bazan, Irma Godoy, Suzana Erico Tanni
OBJECTIVE: To determine the impact of adherence to long-term oxygen therapy (LTOT) on quality of life, dyspnea, and exercise capacity in patients with COPD and exertional hypoxemia followed for one year. METHODS: Patients experiencing severe hypoxemia during a six-minute walk test (6MWT) performed while breathing room air but not at rest were included in the study. At baseline and after one year of follow-up, all patients were assessed for comorbidities, body composition, SpO2, and dyspnea, as well as for anxiety and depression, having also undergone spirometry, arterial blood gas analysis, and the 6MWT with supplemental oxygen...
September 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
L Bugadze, N Manjavidze, L Jorjoliani
The aim of the study - low circulating vitamin D level maybe related to poor asthma control status and decreased lung function. The aim of our research is to establish correlation between serum vitamin D level, asthma control status and lung function. The study was performed in children aged 6-15 years old, including patients with asthma (n=50), who referred to Sachkhere medical center for a visit. The status of asthma control in the basic group was classified as controlled (n=31) and uncontrolled (n=19). The children underwent serum vitamin D and IgE level, spirometry and skin prick tests for the study...
October 2018: Georgian Medical News
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