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https://www.readbyqxmd.com/read/30516532/can-flecainide-totally-eliminate-bidirectional-ventricular-tachycardia-in-pediatric-patients-with-andersen-tawil-syndrome
#1
Yakup Ergül, Senem Özgür, Sertaç Hanedan Onan, Volkan Tuzcu
Andersen-Tawil syndrome (ATS) is a disorder that causes episodes of muscle weakness (periodic paralysis), changes in heart rhythm, and developmental abnormalities. QT prolongation and ventricular arrhythmias, including bidirectional ventricular tachycardia (VT) and polymorphic VT, may occur. About 60% of all cases of the disorder arecaused by mutations in the KCNJ2 gene. A 13-year-old female patient was referred for frequent premature ventricular contractions. Suspicion of ATS due to dysmorphic findings, electrocardiogram changes, and periodic muscle weakness was genetically confirmed...
December 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/30447383/attitudes-beliefs-and-practices-of-pediatric-palliative-care-physicians-regarding-the-use-of-methadone-in-children-with-advanced-cancer
#2
Kevin Madden, Diane Liu, Eduardo Bruera
CONTEXT: Methadone is a long-acting opioid known for its unique pharmacokinetic and pharmacodynamic properties. Most research on methadone in children is limited to its effect on the prolongation of the corrected QT (QTc) interval. OBJECTIVES: To better understand the attitudes, beliefs, and practices of pediatric palliative care physicians regarding the use of methadone in children with advanced cancer. METHODS: A survey was sent to The American Academy of Pediatrics Section of Hospice and Palliative Medicine LISTSERV®...
November 14, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/30371107/lack-of-utility-in-performing-blood-glucose-measurement-and-electrocardiogram-in-the-outpatient-evaluation-of-benign-pediatric-syncope
#3
Ayush Gupta, William Bonadio
We aimed to determine the frequency of blood glucose and electrocardiogram (EKG) abnormalities in previously healthy children who present to an emergency department (ED) with a diagnosis of benign syncope. Chart review of consecutive children aged 5 to 18 years presenting to the pediatric ED from 2004 to 2014 with a discharge diagnosis of benign syncope was done. Of 969 patients, hypoglycemia (serum glucose <60 mg/dL) was present in only 3 cases (0.3%). Of 754 patients with EKG performed, only 4 cases (0...
October 29, 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/30351471/application-of-pediatric-appropriate-use-criteria-for-initial-outpatient-evaluation-of-asymptomatic-patients-with-abnormal-electrocardiograms
#4
Soham Dasgupta, Shae Anderson, Michael Kelleman, Ritu Sachdeva
INTRODUCTION: In the pediatric Appropriate Use Criteria (AUC), abnormal electrocardiogram (ECG) in an asymptomatic patient has been rated as an "Appropriate" indication for transthoracic echocardiogram (TTE). We hypothesized that the yield of abnormal findings on TTE for this indication will be low. METHODS: All asymptomatic patients (≤ 18 years) from January 1, 2015 to December 31, 2017 who underwent initial outpatient evaluation at our center and had a TTE ordered for an abnormal ECG, were included...
October 23, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/30335689/seizures-meds-and-vtach-a-journey-to-a-brugada-diagnosis
#5
David P Fitzgerald, Srikant Das, Matthew P Malone, B Shane Holland, Stephen M Schexnayder
Sudden cardiac arrest of cardiac etiology is rare in children and adolescents and most often occurs with exertion. Conversely, syncope is a common pediatric emergency department complaint but rarely is associated with a serious underlying cardiac disorder. This report describes a case of the channelopathy Brugada syndrome (BrS) as a cause of sudden cardiac arrest in a febrile preadolescent child taking medications known to affect cardiac conduction. The patient received cardiopulmonary resuscitation and was successfully defibrillated...
October 17, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/30333292/echocardiography-guided-percutaneous-closure-of-patent-ductus-arteriosus-without-arterial-access-feasibility-and-safety-for-a-new-strategy
#6
Weizhi Zhang, Lei Gao, Wancun Jin, Qin Wu, Shijun Hu, Yifeng Yang, Tianli Zhao
To evaluate the feasibility and safety of device closure of patent ductus arteriosus (PDA) using only venous access under echocardiography guidance alone.
 Methods: A total of 102 consecutive pediatric patients underwent transcatheter PDA closure without arterial access, under the guidance of only echocardiography. The patients were followed up by clinical examination, electrocardiogram, and echocardiogram at 1, 3, 6 12, and 24 months.
 Results: Transvenous PDA closure under echocardiographic guidance was successful in 99 (97...
September 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/30271014/predictors-of-abnormal-electrocardiograms-in-the-pediatric-emergency-department
#7
Shiv Gandhi, Miranda Lin, Sharon R Smith, Jesse J Sturm
Background: Electrocardiograms (ECGs) are ordered in the pediatric emergency room for a wide variety of chief complaints. Objectives: Criteria are lacking as to when physicians should obtain ECGs. This study uses a large retrospective cohort of 880 pediatric emergency department (ED) patients to highlight objective criteria including significant medical history and specific vital sign abnormalities to guide clinicians as to which patients might have an abnormal ECG...
September 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/30254039/brugada-syndrome-associated-with-adolescent-loperamide-abuse
#8
Bryan Stefek, L Timothy Wolfe, Mark Cohen
We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram. He was treated for anxiety and withdrawal. There were no documented dysrhythmias. His Brugada pattern resolved by hospital day 5 and remained resolved 12 days postadmission. Genetic testing revealed a heterozygous missense mutation in the SCN5A gene (c. 5038G>A, p. Ala1680Thr), which has been reported in association with Brugada syndrome...
October 2018: Pediatrics
https://www.readbyqxmd.com/read/30214250/rupatadine-oral-solution-for-2-5-year-old-children-with-allergic-rhinitis-a-safety-open-label-prospective-study
#9
Eva Santamaría, Iñaki Izquierdo, Marta Valle, Jan Vermeulen, Paul Potter
Background: There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and urticaria. In this study, AR symptoms were evaluated before and after daily 1 mg/mL rupatadine oral solution administration in 2-5-year-old children. Methods: A multicenter open-label study was carried out in 2-5-year-old children with AR. Safety assessments were collected during the study including spontaneous adverse events, vital signs, and electrocardiogram (QTc interval)...
2018: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/30188452/evaluation-of-a-magnetic-tracking-and-electrocardiogram-based-tip-confirmation-system-for-peripherally-inserted-central-catheters-in-pediatric-patients
#10
Nina Rosche, Wolfgang Stehr
The purpose of this study was to investigate whether a magnetic tracking and electrocardiogram-based tip confirmation system (TCS) (Sherlock 3CG Tip Confirmation System; Bard, Covington, GA) permits safe and correct placement of a peripherally inserted central catheter (PICC) in the pediatric population. A total of 144 PICCs were placed using the TCS. After excluding participants for various reasons, 112/121 (92.56%) of PICCs were appropriately placed using the TCS. The TCS confirmed tip location an average of 7 to 18 minutes faster than radiographic imaging...
September 2018: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/30152133/pediatric-noncompaction-patients-with-high-spatial-qrs-t-angles-are-at-increased-risk-for-ventricular-tachycardia
#11
Daniel Cortez, Nandita Sharma, Jason R Imundo
INTRODUCTION: Noncompaction cardiomyopathy (NCCM) patients may develop sustained ventricular arrhythmias (VA). Currently no known electrocardiogram (ECG) parameter has demonstrated predictive value for VA development. The spatial QRS-T angle has demonstrated ability to identify VA in other cardiomyopathy populations. METHODS: A total of 39 patients with NCCM, defined by compact to non-compact ratio of >2.3 by magnetic resonance imaging, were assessed. The first ECG taken at time of MRI was assessed utilizing the heart rate, the QRS duration (QRSd), the corrected QT interval (QTc), and the spatial QRS-T angle (SPQRS-T angle, three-dimensional angle between the QRS and T-wave vectors) were assessed...
August 27, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/30080938/echocardiographic-diagnosis-of-atrial-flutter-in-a-neonate
#12
Samantha Low, Carmen Kiper, Aimee Armstrong, Clifford L Cua
A pregnant female presented at 37 weeks of gestation in labor. The fetus was noted to be tachycardic on fetal monitor. Postnatally, the male neonate was still noted to be tachycardic with heart rates in the low 200 bpm range. EKG was consistent with tachycardia, but rhythm diagnosis was not definitively made. Echocardiogram with M-mode analysis clearly demonstrated 2:1 atrial to ventricular contraction pattern consistent with atrial flutter. The neonate was subsequently transferred to a tertiary pediatric hospital where the diagnosis of atrial flutter was confirmed...
September 2018: Echocardiography
https://www.readbyqxmd.com/read/30054453/r-wave-modified-tissue-doppler-imaging-myocardial-performance-index-for-the-assessment-of-cardiac-function-in-children-with-congestive-heart-failure-a-feasibility-study
#13
Ying Tang, Shanliang Zhu, Jun Chen, Lichun Hua
BACKGROUND The aim of this study was to evaluate the feasibility of an R-wave modified tissue Doppler imaging (TDI) myocardial performance index (MPI), or MPI TDI-R, for the assessment of cardiac function in children with congestive heart failure (CHF). MATERIAL AND METHODS Forty children with CHF and 40 normal children were evaluated using the modified pediatric Ross heart failure grading system. TDI recorded the spectrum of diastolic function at the mitral valve annulus to measure the MPI. Twelve-lead electrocardiogram (ECG) measured the R-wave in the QRS complex, resulting in the modified MPI TDI-R...
July 28, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29989175/evaluation-of-left-ventricular-false-tendons-in-children-with-idiopathic-left-ventricular-tachycardia
#14
Anthony Merlocco, David W Brown, Kimberlee Gauvreau, Douglas Y Mah, John K Triedman, Mark E Alexander, Edward P Walsh
BACKGROUND: Left ventricular false tendons (FT) traverse the ventricular cavity and are thought to have some association with idiopathic left ventricular tachycardia (ILVT). However, reported prevalence of FT varies widely, making correlation difficult. Superior echocardiographic windows of pediatric patients may permit better analysis of FT in ILVT. Our study describes the relationship between FT and ILVT in young patients. METHODS: Retrospective case-control study of 30 ILVT patients with 98 controls compared for FT...
September 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29958610/utilization-of-diagnostic-testing-for-pediatric-sensorineural-hearing-loss
#15
Carissa J Wentland, Evette A Ronner, Razan A Basonbul, Sandeep Pinnapureddy, Leila Mankarious, Donald Keamy, Daniel J Lee, Michael S Cohen
BACKGROUND/OBJECTIVE: Sensorineural hearing loss is a common diagnosis among children. The diagnostic workup varies widely among practitioners. This study's aim was to assess the utilization of diagnostic testing for SNHL and determine the yield of each test. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary care center. SUBJECTS: 827 patients with a diagnosis of SNHL from January 1, 2011 to January 1, 2015...
August 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29930156/electrocardiograms-in-healthy-north-american-children-in-the-digital-age
#16
Elizabeth V Saarel, Suzanne Granger, Jonathan R Kaltman, L LuAnn Minich, Martin Tristani-Firouzi, Jeffrey J Kim, Kathleen Ash, Sabrina S Tsao, Charles I Berul, Elizabeth A Stephenson, David G Gamboa, Felicia Trachtenberg, Peter Fischbach, Victoria L Vetter, Richard J Czosek, Tiffanie R Johnson, Jack C Salerno, Nicole B Cain, Robert H Pass, Ilana Zeltser, Eric S Silver, Joshua R Kovach, Mark E Alexander
BACKGROUND: Interpretation of pediatric ECGs is limited by lack of accurate sex- and race-specific normal reference values obtained with modern technology for all ages. We sought to obtain contemporary digital ECG measurements in healthy children from North America, to evaluate the effects of sex and race, and to compare our results to commonly used published datasets. METHODS: Digital ECGs (12-lead) were retrospectively collected for children ≤18 years old with normal echocardiograms at 19 centers in the Pediatric Heart Network...
July 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29866594/etiologies-and-yield-of-diagnostic-testing-in-children-presenting-to-the-emergency-department-with-altered-mental-status
#17
Katharine Button, Andrew Capraro, Michael Monuteaux, Rebekah Mannix
OBJECTIVES: To identify etiologies of altered mental status in pediatric patients presenting to the emergency department (ED) and to characterize the yield of diagnostic testing in these patients. STUDY DESIGN: Retrospective chart review of children aged 1-17 years presenting to a pediatric tertiary care ED between December 31, 2013 and December 31, 2014 with a chief complaint or International Classification of Disease, Ninth Edition code of altered mental status...
September 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29796952/cardiac-diagnostics-before-oral-propranolol-therapy-in-infantile-hemangioma-retrospective-evaluation-of-234-infants
#18
Giovanni Frongia, Ji-Oun Byeon, Raoul Arnold, Arianeb Mehrabi, Patrick Günther
BACKGROUND: The indication and extent of cardiac screening before oral propranolol therapy (OPT) in patients with infantile hemangioma (IH) has been challenged. In this study, we evaluated pre-OPT cardiac diagnostics in a pediatric IH cohort in our department. METHODS: Retrospective chart review of infants ≤ 12 months old with IH undergoing OPT. The diagnostics prior to OPT, occurrence of complications, and outcome were recorded. RESULTS: A total of 234 patients were evaluated...
June 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29794950/adolescent-seizure-in-the-emergency-department-due-to-concomitant-brugada-syndrome
#19
REVIEW
Beau Baum, Oscar Ingaramo, David Chao
Brugada syndrome is an increasingly discussed entity in the emergency medicine and cardiology literature. However, there are few cases reported in the pediatric population. Seizure is a presentation common to pediatric emergency departments. This case report describes the clinical course, workup, and differential diagnosis of a 15-year-old male adolescent with first-time seizure and Brugada pattern on electrocardiogram. A brief review of the literature follows the case presentation.
August 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29784491/neonatal-and-pediatric-arrhythmias-clinical-and-electrocardiographic-aspects
#20
REVIEW
Fabrizio Drago, Irma Battipaglia, Corrado Di Mambro
Arrhythmias have acquired a specific identity in pediatric cardiology, but for pediatric cardiologists it has always been difficult to recognize and treat them. Changes in anatomy and physiology result in electrocardiogram features that differ from the normal adult pattern and vary according to the age of the child. Sinus arrhythmia, ectopic atrial rhythm, "wandering pacemaker," and junctional rhythm can be normal characteristics in children (15%-25% of healthy children can have these rhythms on the electrocardiogram)...
June 2018: Cardiac Electrophysiology Clinics
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