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https://www.readbyqxmd.com/read/30335689/seizures-meds-and-vtach-a-journey-to-a-brugada-diagnosis
#1
David P Fitzgerald, Srikant Das, Matthew P Malone, B Shane Holland, Stephen M Schexnayder
Sudden cardiac arrest of cardiac etiology is rare in children and adolescents and most often occurs with exertion. Conversely, syncope is a common pediatric emergency department complaint but rarely is associated with a serious underlying cardiac disorder. This report describes a case of the channelopathy Brugada syndrome (BrS) as a cause of sudden cardiac arrest in a febrile preadolescent child taking medications known to affect cardiac conduction. The patient received cardiopulmonary resuscitation and was successfully defibrillated...
October 17, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/30333292/echocardiography-guided-percutaneous-closure-of-patent-ductus-arteriosus-without-arterial-access-feasibility-and-safety-for-a-new-strategy
#2
Weizhi Zhang, Lei Gao, Wancun Jin, Qin Wu, Shijun Hu, Yifeng Yang, Tianli Zhao
To evaluate the feasibility and safety of device closure of patent ductus arteriosus (PDA) using only venous access under echocardiography guidance alone.
 Methods: A total of 102 consecutive pediatric patients underwent transcatheter PDA closure without arterial access, under the guidance of only echocardiography. The patients were followed up by clinical examination, electrocardiogram, and echocardiogram at 1, 3, 6 12, and 24 months.
 Results: Transvenous PDA closure under echocardiographic guidance was successful in 99 (97...
September 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/30327703/age-makes-a-difference-symptoms-in-pediatric-supraventricular-tachycardia
#3
Amanda Quattrocelli, Janet Lang, Andrew Davis, Andreas Pflaumer
Background: Supraventricular tachycardia is a group of rhythm disturbances that affect 1 in 300-1200 Australian children annually. The differentiation of supraventricular tachycardia (SVT) symptoms and age of onset according to their subtype is not well understood in the pediatric population. Most studies rely on ECG criteria only to characterize the subtype of the SVT, which is not applicable to all subtypes. The purpose of this study was to identify the symptoms and ages of onset of SVT subtypes, and to analyze whether ethnicity or severity correlated with the SVT subtype confirmed in an invasive Electrophysiology (EP) study...
October 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/30271014/predictors-of-abnormal-electrocardiograms-in-the-pediatric-emergency-department
#4
Shiv Gandhi, Miranda Lin, Sharon R Smith, Jesse J Sturm
Background: Electrocardiograms (ECGs) are ordered in the pediatric emergency room for a wide variety of chief complaints. Objectives: Criteria are lacking as to when physicians should obtain ECGs. This study uses a large retrospective cohort of 880 pediatric emergency department (ED) patients to highlight objective criteria including significant medical history and specific vital sign abnormalities to guide clinicians as to which patients might have an abnormal ECG...
September 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/30260996/can-smartphone-wireless-ecgs-be-used-to-accurately-assess-ecg-intervals-in-pediatrics-a-comparison-of-mobile-health-monitoring-to-standard-12-lead-ecg
#5
Melanie R F Gropler, Aarti S Dalal, George F Van Hare, Jennifer N Avari Silva
BACKGROUND: Arrhythmias in children are often paroxysmal, complicating the ability to capture the abnormal rhythm on routine ECG during an outpatient visit. The Alivecor Kardia Mobile (KM) device is a wireless mobile health (mHealth) device that generates a single lead ECG tracing with a FDA-approved algorithm for detection of atrial fibrillation in adults. OBJECTIVE: The goal of this study is to assess the accuracy of interval measurements on KM tracings by directly comparing to standard 12-lead ECGs in pediatric patients...
2018: PloS One
https://www.readbyqxmd.com/read/30254039/brugada-syndrome-associated-with-adolescent-loperamide-abuse
#6
Bryan Stefek, L Timothy Wolfe, Mark Cohen
We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram. He was treated for anxiety and withdrawal. There were no documented dysrhythmias. His Brugada pattern resolved by hospital day 5 and remained resolved 12 days postadmission. Genetic testing revealed a heterozygous missense mutation in the SCN5A gene (c. 5038G>A, p. Ala1680Thr), which has been reported in association with Brugada syndrome...
October 2018: Pediatrics
https://www.readbyqxmd.com/read/30214250/rupatadine-oral-solution-for-2-5-year-old-children-with-allergic-rhinitis-a-safety-open-label-prospective-study
#7
Eva Santamaría, Iñaki Izquierdo, Marta Valle, Jan Vermeulen, Paul Potter
Background: There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and urticaria. In this study, AR symptoms were evaluated before and after daily 1 mg/mL rupatadine oral solution administration in 2-5-year-old children. Methods: A multicenter open-label study was carried out in 2-5-year-old children with AR. Safety assessments were collected during the study including spontaneous adverse events, vital signs, and electrocardiogram (QTc interval)...
2018: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/30188452/evaluation-of-a-magnetic-tracking-and-electrocardiogram-based-tip-confirmation-system-for-peripherally-inserted-central-catheters-in-pediatric-patients
#8
Nina Rosche, Wolfgang Stehr
The purpose of this study was to investigate whether a magnetic tracking and electrocardiogram-based tip confirmation system (TCS) (Sherlock 3CG Tip Confirmation System; Bard, Covington, GA) permits safe and correct placement of a peripherally inserted central catheter (PICC) in the pediatric population. A total of 144 PICCs were placed using the TCS. After excluding participants for various reasons, 112/121 (92.56%) of PICCs were appropriately placed using the TCS. The TCS confirmed tip location an average of 7 to 18 minutes faster than radiographic imaging...
September 2018: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/30152133/pediatric-noncompaction-patients-with-high-spatial-qrs-t-angles-are-at-increased-risk-for-ventricular-tachycardia
#9
Daniel Cortez, Nandita Sharma, Jason R Imundo
INTRODUCTION: Noncompaction cardiomyopathy (NCCM) patients may develop sustained ventricular arrhythmias (VA). Currently no known electrocardiogram (ECG) parameter has demonstrated predictive value for VA development. The spatial QRS-T angle has demonstrated ability to identify VA in other cardiomyopathy populations. METHODS: A total of 39 patients with NCCM, defined by compact to non-compact ratio of >2.3 by magnetic resonance imaging, were assessed. The first ECG taken at time of MRI was assessed utilizing the heart rate, the QRS duration (QRSd), the corrected QT interval (QTc), and the spatial QRS-T angle (SPQRS-T angle, three-dimensional angle between the QRS and T-wave vectors) were assessed...
August 27, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/30142610/depiction-of-the-native-coronary-arteries-during-ecg-triggered-high-pitch-dual-source-coronary-computed-tomography-angiography-in-children-determinants-of-image-quality
#10
Christian A Barrera, Hansel J Otero, Ammie M White, David Saul, David M Biko
OBJECTIVE: Assess the image quality of ECG-triggered High-Pitch Dual-Source CTA for the evaluation of native coronaries in children. MATERIALS AND METHODS: Between August 2014 and September 2017, 45 children with morphologically normal cardiac chambers had cardiac prospective ECG-triggered High-Pitch Dual-Source CTA. Two pediatric radiologists blinded to clinical data, independently reviewed each case. The coronary arteries were evaluated using a four-point scale quality score according to the coronary segment...
August 18, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/30131047/-key-points-of-the-2017-acc-aha-hrs-guideline-for-the-evaluation-and-management-of-patients-with-syncope
#11
G A Golovina, D V Duplyakov
The article presents key points of published in March 2017, Guideline for the Evaluation and Management of Patients With Syncope (A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society). This document contains summary and analysis of evidence base and accumulated experience in this field and reflect further development of the problem of the management of adult and pediatric patients with suspected syncope. Traditionally, the basis of diagnostic algorithm of these patients has been primary examination, and in the present guideline one can find strengthening of the importance of anamnestic criteria, and supplementation of ECG criteria of arrhythmic syncope...
August 2018: Kardiologiia
https://www.readbyqxmd.com/read/30056397/clinical-course-and-treatment-of-children-and-adolescents-with-the-preexcitation-syndrome-own-studies
#12
Aleksandra Stasiak, Katarzyna Niewiadomska-Jarosik, Piotr Kędziora
INTRODUCTION: Essentially, preexcitation syndrome is the presence of an accessory pathway in the heart, which can lead to serious consequences, ranging from atrioventricular reentrant tachycardia to sudden cardiac death. Wolff-Parkinson-White syndrome is the most common preexcitation syndrome. AIM OF THE STUDY: The aim of the study was to evaluate the clinical course of the disease, as well as the treatment of children and adolescents hospitalized in the Department of Pediatric Cardiology in the years 2008-2015...
2018: Developmental Period Medicine
https://www.readbyqxmd.com/read/30054453/r-wave-modified-tissue-doppler-imaging-myocardial-performance-index-for-the-assessment-of-cardiac-function-in-children-with-congestive-heart-failure-a-feasibility-study
#13
Ying Tang, Shanliang Zhu, Jun Chen, Lichun Hua
BACKGROUND The aim of this study was to evaluate the feasibility of an R-wave modified tissue Doppler imaging (TDI) myocardial performance index (MPI), or MPI TDI-R, for the assessment of cardiac function in children with congestive heart failure (CHF). MATERIAL AND METHODS Forty children with CHF and 40 normal children were evaluated using the modified pediatric Ross heart failure grading system. TDI recorded the spectrum of diastolic function at the mitral valve annulus to measure the MPI. Twelve-lead electrocardiogram (ECG) measured the R-wave in the QRS complex, resulting in the modified MPI TDI-R...
July 28, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29997001/evaluation-of-t-wave-alternans-in-pediatric-patients-with-chronic-renal-failure
#14
Olgu Hallioglu, Meryem Keceli, Gulcin Bozlu, Ali Delibas, Derya Karpuz, Hüseyin Selvi
INTRODUCTION: Microvolt T-wave alternans (TWA) is known to be useful in prediction of ischemia and sudden death in high-risk populations and there are no studies in children with chronic renal failure (CRF). Cardiac problems seem to be responsible for an important part of death in children and young adults with CRF. The aim of this study is to evaluate Holter microvolts TWA measurements in children with CRF comparing to the control group. METHODS: This prospective study included 40 patients with CRF and 48 healthy controls...
July 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29989175/evaluation-of-left-ventricular-false-tendons-in-children-with-idiopathic-left-ventricular-tachycardia
#15
Anthony Merlocco, David W Brown, Kimberlee Gauvreau, Douglas Y Mah, John K Triedman, Mark E Alexander, Edward P Walsh
BACKGROUND: Left ventricular false tendons (FT) traverse the ventricular cavity and are thought to have some association with idiopathic left ventricular tachycardia (ILVT). However, reported prevalence of FT varies widely, making correlation difficult. Superior echocardiographic windows of pediatric patients may permit better analysis of FT in ILVT. Our study describes the relationship between FT and ILVT in young patients. METHODS: Retrospective case-control study of 30 ILVT patients with 98 controls compared for FT...
September 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29958610/utilization-of-diagnostic-testing-for-pediatric-sensorineural-hearing-loss
#16
Carissa J Wentland, Evette A Ronner, Razan A Basonbul, Sandeep Pinnapureddy, Leila Mankarious, Donald Keamy, Daniel J Lee, Michael S Cohen
BACKGROUND/OBJECTIVE: Sensorineural hearing loss is a common diagnosis among children. The diagnostic workup varies widely among practitioners. This study's aim was to assess the utilization of diagnostic testing for SNHL and determine the yield of each test. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary care center. SUBJECTS: 827 patients with a diagnosis of SNHL from January 1, 2011 to January 1, 2015...
August 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29930156/electrocardiograms-in-healthy-north-american-children-in-the-digital-age
#17
Elizabeth V Saarel, Suzanne Granger, Jonathan R Kaltman, L LuAnn Minich, Martin Tristani-Firouzi, Jeffrey J Kim, Kathleen Ash, Sabrina S Tsao, Charles I Berul, Elizabeth A Stephenson, David G Gamboa, Felicia Trachtenberg, Peter Fischbach, Victoria L Vetter, Richard J Czosek, Tiffanie R Johnson, Jack C Salerno, Nicole B Cain, Robert H Pass, Ilana Zeltser, Eric S Silver, Joshua R Kovach, Mark E Alexander
BACKGROUND: Interpretation of pediatric ECGs is limited by lack of accurate sex- and race-specific normal reference values obtained with modern technology for all ages. We sought to obtain contemporary digital ECG measurements in healthy children from North America, to evaluate the effects of sex and race, and to compare our results to commonly used published datasets. METHODS: Digital ECGs (12-lead) were retrospectively collected for children ≤18 years old with normal echocardiograms at 19 centers in the Pediatric Heart Network...
July 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29908370/gender-differences-in-patients-with-brugada-syndrome-and-arrhythmic-events-data-from-a-survey-on-arrhythmic-events-in-678-patients
#18
Anat Milman, Jean-Baptiste Gourraud, Antoine Andorin, Pieter G Postema, Frederic Sacher, Philippe Mabo, Giulio Conte, Carla Giustetto, Georgia Sarquella-Brugada, Aviram Hochstadt, Sung-Hwan Kim, Jimmy J M Juang, Shingo Maeda, Yoshihide Takahashi, Tsukasa Kamakura, Takeshi Aiba, Eran Leshem, Yoav Michowitz, Michael Rahkovich, Yuka Mizusawa, Elena Arbelo, Zhengrong Huang, Isabelle Denjoy, Yanushi D Wijeyeratne, Carlo Napolitano, Ramon Brugada, Ruben Casado-Arroyo, Jean Champagne, Leonardo Calo, Jacob Tfelt-Hansen, Silvia G Priori, Masahiko Takagi, Christian Veltmann, Pietro Delise, Domenico Corrado, Elijah R Behr, Fiorenzo Gaita, Gan-Xin Yan, Josep Brugada, Antoine Leenhardt, Arthur A M Wilde, Pedro Brugada, Kengo F Kusano, Kenzo Hirao, Gi-Byoung Nam, Vincent Probst, Bernard Belhassen
BACKGROUND: There is limited information on gender differences in patients with Brugada syndrome (BrS) who experienced arrhythmic events (AEs). OBJECTIVE: The purpose of this study was to compare clinical, electrocardiographic (ECG), electrophysiological, and genetic characteristics between males and females in patients with BrS with their first AE. METHODS: The multicenter Survey on Arrhythmic Events in BRUgada Syndrome collected data on the first AE in 678 patients with BrS including 619 males (91...
October 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29866594/etiologies-and-yield-of-diagnostic-testing-in-children-presenting-to-the-emergency-department-with-altered-mental-status
#19
Katharine Button, Andrew Capraro, Michael Monuteaux, Rebekah Mannix
OBJECTIVES: To identify etiologies of altered mental status in pediatric patients presenting to the emergency department (ED) and to characterize the yield of diagnostic testing in these patients. STUDY DESIGN: Retrospective chart review of children aged 1-17 years presenting to a pediatric tertiary care ED between December 31, 2013 and December 31, 2014 with a chief complaint or International Classification of Disease, Ninth Edition code of altered mental status...
September 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29796952/cardiac-diagnostics-before-oral-propranolol-therapy-in-infantile-hemangioma-retrospective-evaluation-of-234-infants
#20
Giovanni Frongia, Ji-Oun Byeon, Raoul Arnold, Arianeb Mehrabi, Patrick Günther
BACKGROUND: The indication and extent of cardiac screening before oral propranolol therapy (OPT) in patients with infantile hemangioma (IH) has been challenged. In this study, we evaluated pre-OPT cardiac diagnostics in a pediatric IH cohort in our department. METHODS: Retrospective chart review of infants ≤ 12 months old with IH undergoing OPT. The diagnostics prior to OPT, occurrence of complications, and outcome were recorded. RESULTS: A total of 234 patients were evaluated...
June 2018: World Journal of Pediatrics: WJP
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