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Ecg Strain

Jarren C Kay, Gerald C Claghorn, Zoe Thompson, Thomas G Hampton, Theodore Garland
Changes in cardiac function that occur with exercise training have been studied in detail, but those accompanying evolved increases in the duration or intensity of physical activity are poorly understood. To address this gap, we studied electrocardiograms (ECGs) of mice from an artificial selection experiment in which four replicate lines are bred for high voluntary wheel running (HR) while four non-selected lines are maintained as controls (C). ECGs were recorded using an ECGenie (Mouse Specifics, Inc.) both before and after six days of wheel access (as used in the standard protocol to select breeders)...
November 30, 2018: Physiology & Behavior
Mikko Jalanko, Tiina Heliö, Pirjo Mustonen, Jorma Kokkonen, Heini Huhtala, Mika Laine, Pertti Jääskeläinen, Mika Tarkiainen, Kirsi Lauerma, Petri Sipola, Markku Laakso, Johanna Kuusisto, Kjell Nikus
OBJECTIVES: The sensitivity and specificity of the conventional 12-lead ECG to identify carriers of hypertrophic cardiomyopathy (HCM) - causing mutations without left ventricular hypertrophy (LVH) has been limited. We assessed the ability of novel electrocardiographic parameters to improve the detection of HCM mutation carriers. METHODS: We studied 140 carriers (G+) of the TPM1-Asp175Asn or MYBPC3-Gln1061X pathogenic variants for HCM: The G+/LVH+ group (n = 98) consisted of mutation carriers with LVH and the G+/LVH- group (n = 42) without LVH...
November 2018: Journal of Electrocardiology
Daniel X Augustine, Liz Howard
PURPOSE OF REVIEW: The changes that occur in athlete's heart are influenced by a number of factors including age, gender, ethnicity and the type of cardiovascular training. It is therefore important that the clinician is able to integrate all of these factors when assessing athletes to be able to guide investigations appropriately and to distinguish pathology from physiology. This review discusses the potential diagnostic conundrums when trying to differentiate physiological left ventricular hypertrophy from pathological hypertrophic cardiomyopathy in athletes...
October 26, 2018: Current Treatment Options in Cardiovascular Medicine
Jacek Kurzawski, Agnieszka Janion-Sadowska, Andrzej Gackowski, Marianna Janion, Łukasz Zandecki, Magdalena Chrapek, Marcin Sadowski
To determine the left atrial longitudinal strain discrimination threshold of atrial fibrillation (AF) in patients with dilated cardiomyopathy (DCM). A total of 100 DCM patients and LVEF < 25% were included. Of them, 50 had sinus rhythm (SR), and 50 had AF. Patients with significant valvular disease, cardiac pacemakers and prosthetic valves were excluded. Speckle tracking echocardiography was performed to visualize the inferior and lateral walls of the left atrium as well as the interatrial septum. The Q-Analysis software was used to assess left atrial contractile strain (εCT ) during the atrial systole and left atrial conduit strain (εCD ) during the atrial filling...
October 19, 2018: International Journal of Cardiovascular Imaging
Diana Rivero, Mohammad Alhamaydeh, Ziad Faramand, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Barbara Drew, Salah Al-Zaiti
BACKGROUND: Nonspecific ST-T repolarization (NST) abnormalities alter the ST-segment for reasons often unrelated to acute myocardial ischemia, which could contribute to misdiagnosis or inappropriate treatment. We sought to define the prevalence of NST patterns in patients with chest pain and evaluate how such patterns correlate with the eventual etiology of chest pain and course of hospitalization. METHODS: This was a prospective observational study that included consecutive prehospital chest pain patients from three tertiary care hospitals in the U...
October 8, 2018: Heart & Lung: the Journal of Critical Care
Elizabeth Iffrig, John S Wilson, Xiadong Zhong, John N Oshinski
BACKGROUND: Knowledge of tissue properties of the abdominal aorta can improve understanding of vascular disease and guide interventional approaches. Existing MRI methods to quantify aortic wall displacement and strain are unable to discern circumferential heterogeneity. PURPOSE: To assess regional variation in abdominal aortic wall displacement and strain as a function of circumferential position using spiral cine displacement encoding with stimulated echoes (DENSE)...
October 8, 2018: Journal of Magnetic Resonance Imaging: JMRI
Ravi Vijapurapu, Sabrina Nordin, Shanat Baig, Boyang Liu, Stefania Rosmini, Joao Augusto, Michel Tchan, Derralynn A Hughes, Tarekegn Geberhiwot, James C Moon, Richard Paul Steeds, Rebecca Kozor
INTRODUCTION: Detecting early cardiac involvement in Fabry disease (FD) is important because therapy may alter disease progression. Cardiovascular magnetic resonance (CMR) can detect T1 lowering, representing myocardial sphingolipid storage. In many diseases, early mechanical dysfunction may be detected by abnormal global longitudinal strain (GLS). We explored the relationship of early mechanical dysfunction and sphingolipid deposition in FD. METHODS: An observational study of 221 FD and 77 healthy volunteers (HVs) who underwent CMR (LV volumes, mass, native T1, GLS, late gadolinium enhancement), ECG and blood biomarkers, as part of the prospective multicentre Fabry400 study...
October 3, 2018: Heart: Official Journal of the British Cardiac Society
Lars Gunnar Klaeboe, Pål H Brekke, Øyvind H Lie, Lars Aaberge, Kristina H Haugaa, Thor Edvardsen
Aims: Left bundle branch block (LBBB) is a frequent conduction abnormality after transcatheter aortic valve implantation (TAVI). We aimed to investigate how TAVI procedure related conduction abnormalities influence ventricular mechanics and prognosis, with particular focus on new-onset persistent LBBB. Methods and results: A total of 140 consecutive patients with severe aortic stenosis (83 ± 8 years old, 49% women) undergoing TAVI in a single tertiary centre were included in a repeated measures study...
September 20, 2018: European Heart Journal Cardiovascular Imaging
Waldemar Elikowski, Małgorzata Małek-Elikowska, Monika Lisiecka, Zofia Trypuć, Iwona Mozer-Lisewska
Influenza is associated with a high prevalence of cardiac complications, including myocarditis and exacerbation of ischemic heart disease or heart failure (HF). However, only four cases of stress-induced takotsubo cardiomyopathy (TC), all of them triggered by virus A influenza, have been reported so far. Another two TC cases after anti-influenza vaccination are also available in the literature. The authors describe a new case of TC, this time provoked by influenza B. An 89-year-old female with a history of hypertension and chronic obstructive pulmonary disease (COPD) was admitted due to a fever (39oC), muscle aches and cough...
August 29, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Michal Fikrle, Tomas Palecek, Josef Marek, Petr Kuchynka, Ales Linhart
AIM OF THE STUDY: To assess the diagnostic utility of a simplified approach to relative apical sparing of longitudinal strain (RAS LS) using only an apical four-chamber view (A4C) in patients with AL amyloid cardiomyopathy (ALAC). METHODS: We retrospectively evaluated echocardiographic recordings of 20 patients with ALAC, 20 patients with Fabry disease-related cardiomyopathy (FD), and 20 patients with concentric hypertensive left ventricular hypertrophy (HLVH) matched for mean LV mean thickness...
September 17, 2018: Echocardiography
Serkan Fazlı Çelik, Emre Baratalı, Ahmet Sami Güven, Yasemin Altuner Torun
PURPOSE: Although there is a higher risk of structural cardiac disease in people with epilepsy, there is no detailed advanced analysis of cardiac functions in patients with epilepsy. This study aimed to determine early echocardiographic findings of Left Ventricular (LV) dysfunction using cardiac strain technique in seizure-free children with epilepsy. METHOD: The study investigated 60 children with epilepsy who had no seizures in the preceding 6 months, without any known cardiovascular disease and treated with one antiepileptic drug and 60 healthy subjects who underwent clinical evaluation including electrocardiography (ECG), standard echocardiography, tissue Doppler imaging (TDI) and two-dimensional Speckle Tracking Echocardiography (2DSTE)...
October 2018: Seizure: the Journal of the British Epilepsy Association
Sébastien Rubin, Antoine Cremer, Romain Boulestreau, Claire Rigothier, Sophie Kuntz, Philippe Gosse
BACKGROUND: Malignant hypertension, the most severe form of hypertension, is defined by high blood pressure and acute ischemic organ damage. It has a worse prognosis than other forms of hypertension, especially in black patients. New tools to assess organ damage, especially that of the heart and brain, are now available and may contribute to a better evaluation of these patients. This report improves knowledge of the characteristics of involved organs to facilitate diagnosis and to evaluate the effectiveness of our treatment protocol...
August 16, 2018: Journal of Hypertension
Alex Heyse, Florence Anne, Beatrice Lagae, Hilde Van Haver, Frederik Van Durme
We report a case of takotsubo syndrome (TTS) triggered by herpes encefalitis in the presence of significant triple vessel coronary artery disease (CAD). The typical ECG abnormalities, moderately elevated cardiac enzymes with disproportionally elevated brain natriuretic peptide (BNP) as well as the typical wall motion abnormalities on echocardiography and left ventricular (LV) angiography, were consistent with the diagnosis of TTS with concomitant CAD rather than an acute coronary syndrome. The normalization of the wall motion abnormalities, ejection fraction and longitudinal strain on serial echocardiography all support the diagnosis of takotsubo syndrome, especially in challenging cases...
August 27, 2018: Acta Clinica Belgica
Ingrid Anne Mandy Schierz, Mario Giuffrè, Ettore Piro, Maria Clara Leone, Giuseppa Pinello, Giovanni Corsello
BACKGROUND: Congenital space-occupying thoracic malformations and diaphragmatic hernia have in common pulmonary hypoplasia. Our study aims to assess cardiac involvement during post-natal adaptation. METHODS: A retrospective study was carried out on newborns with prenatally diagnosed intrathoracic mass. Gathering for respiratory distress syndrome (RDS), 35 neonates were compared for clinical course, cardiovascular enzymes, ECG, and ultrasound. RESULTS: The analysis revealed a high left heart defect rate in patients with severe RDS, without being influenced by the laterality...
August 22, 2018: Italian Journal of Pediatrics
Vicente Mora, Ildefonso Roldán, Elena Romero, Assumpció Saurí, Diana Romero, Jana Pérez-Gozalbo, Natalia Ugalde, Javier Bertolín, Melisa Rodriguez-Israel, Carmen Pérez-Olivares Delgado, Jorge A Lowenstein
BACKGROUND: According to the ventricular myocardial band model, the diastolic isovolumetric period is a contraction phenomenon. Our objective was to employ speckle-tracking echocardiography (STE) to analyze myocardial deformation of the left ventricle (LV) and to confirm if it supports the myocardial band model. METHODS: This was a prospective observational study in which 90 healthy volunteers were recruited. We evaluated different types of postsystolic shortening (PSS) from an LV longitudinal strain study...
August 9, 2018: Journal of Cardiovascular Development and Disease
Islam ElSayed Shehata, Cheng-I Cheng, Pei-Hsun Sung, Ahmed S Ammar, Islam Abd El-Moneem El-Sherbiny, Islam Ghanem Ahmed Ghanem
BACKGROUND: Following acute ST elevation myocardial infarction (STEMI), restoration of large-vessel patency does not mean complete perfusion recovery. Little is known regarding the predictors of successful myocardial reperfusion for the STEMI patients undergoing pharmacologic and mechanical reperfusion strategies. AIM OF THE WORK: The aim of this clinical study was to find out the predictors of myocardial functional recovery following reperfusion of acute STEMI, represented by 3-month global longitudinal strain (GLS) value assessed by speckle tracking echocardiography...
October 2018: Echocardiography
Mohammed Al-Hijji, Mohamad Alkhouli, Fahad Alqahtani, Vuyisile T Nkomo, Kevin L Greason, David R Holmes
Electrocardiographic (ECG) strain has been linked to excess cardiovascular morbidity and mortality in asymptomatic patients with aortic stenosis. We aim to determine the differential impact of baseline ECG-strain on long-term mortality after transcatheter aortic valve implantation (TAVI). Patients who underwent TAVI from January 2012 to March 2016 at Mayo Clinic were included. Left ventricular (LV) strain was defined as the presence of ≥1mm convex ST-segment depression with asymmetrical T-wave inversion in leads V5 to V6 on baseline ECG...
June 21, 2018: American Journal of Cardiology
Øyvind H Lie, Christine Rootwelt-Norberg, Lars A Dejgaard, Ida Skrinde Leren, Mathis K Stokke, Thor Edvardsen, Kristina H Haugaa
OBJECTIVES: This study aimed to identify clinical, electrocardiographic (ECG) and cardiac imaging predictors of first-time life-threatening ventricular arrhythmia in patients with arrhythmogenic cardiomyopathy (AC). BACKGROUND: The role of clinical, electrocardiographic, and cardiac imaging parameters in risk stratification of patients without ventricular arrhythmia is unclear. METHODS: We followed consecutive AC probands and mutation-positive family members with no documented ventricular arrhythmia from time of diagnosis to first event...
October 2018: JACC. Cardiovascular Imaging
Anders Svensson, Kerstin Cederlund, Torkel B Brismar, Raquel Themudo
Aortic subvalvular pseudoaneurysms (PSA) are particularly subjected to strain and shear stress forces from blood flow and therefore their size can vary along the heart cycle. Here we describe a case of an aortic subvalvular PSA that shows significant variation in size between systolic and diastolic phase during retrospective ECG-triggered cardiac computed tomography angiography.
June 2018: Acta Radiologica Open
Gary J Hodges, Steven Ah Ferguson, Stephen S Cheung
This study examined the effect of mild hypothermia (a 0.5°C decrease in rectal temperature) on heart rate variability (HRV), with the identical hypothermia protocol performed twice and compared using intraclass correlation coefficient (r) analysis to study the repeatability. Twelve healthy males each completed a Neutral (23°C) and two Cold (0°C) trials. In the Neutral trial participants sat quietly for 30 min. In the Cold trials, baseline data were obtained from a 5-min sample following 30 min of quiet sitting at 23°C, followed by passive exposure to 0°C; hypothermic measures were taken from a 5-min period immediately prior to rectal temperature decreasing by 0...
June 26, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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