keyword
https://read.qxmd.com/read/38546834/integrating-recombinase-polymerase-amplification-and-photosensitization-colorimetric-detection-in-one-tube-for-fast-screening-of-c-sakazakii-in-formula-milk-powder
#1
JOURNAL ARTICLE
Yanying Wang, Ting Zheng, Xianming Li, Peng Wu
Cronobacter sakazakii ( C. sakazakii ) is a widely existing opportunistic pathogen and thus threatens people with low immunity, especially infants. To prevent the outbreak, a rapid and accurate on-site testing method is required. The current standard culture-based method is time-consuming (3-4 days), while the nucleic acid amplification (PCR)-based detection is mostly carried out in central laboratories. Herein, isothermal recombinase polymerase amplification (RPA) coupled with a photosensitization colorimetric assay (PCA) was adopted for the on-site detection of C...
March 28, 2024: Analytical Chemistry
https://read.qxmd.com/read/38546762/estimated-glomerular-filtration-rate-applicability-of-creatinine-based-equations-in-african-children
#2
JOURNAL ARTICLE
Agathe Bikupe Nkoy, Therance Tobo Matoka, Justine Busanga Bukabau, Ernest Kiswaya Sumaili, Veerle Labarque, Lambertus P van den Heuvel, Elena Levtchenko, Etienne Cavalier, Pierre Delanaye, Pépé Mfutu Ekulu, Hans Pottel
BACKGROUND: The Schwartz equation is the most widely used serum creatinine (SCr)-based formula to estimate the glomerular filtration rate (GFR) in children of European descent, but whether this applies to African children is unclear. METHODS: In a cross-sectional study, 513 apparently healthy African children aged 6 to 16 years were randomly recruited in school area of Kinshasa, the Democratic Republic of Congo (DRC). SCr was measured using calibrated enzymatic method...
March 28, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38545269/symptomatic-hypercalcemia-in-an-infant-secondary-to-excessive-consumption-of-almond-milk-as-a-formula-alternative
#3
Whitney C Gulledge, Brittany M Gerald, Kathryn M Sumpter, Nathaniel G Rogers
A 4-month-old previously healthy female presented with persistent nonbloody, nonbilious emesis, decreased urine output, weight loss, fussiness, and lethargy. Serum levels of calcium were increased at 14.1 mg/dL, serum phosphate decreased at 1.6 mg/dL, and serum parathyroid hormone decreased at <4 pg/mL. The patient had been consuming unsweetened almond milk due to inability to find infant formula during a national infant formula shortage. Milk alternatives including almond milk are calorie-poor, low fat, low protein, and too high in free water and calcium to safely be the primary nutrition source for infants...
February 2024: JPGN reports
https://read.qxmd.com/read/38542810/tolerance-and-safety-of-an-anti-regurgitation-formula-containing-locust-bean-gum-pre-and-postbiotics-a-multi-country-multi-center-prospective-randomized-controlled-study-in-infants-with-regurgitation
#4
JOURNAL ARTICLE
Silvia Salvatore, Viktoriia Klymenko, Yuliia Karpushenko, Maria Durczak-Hilleman, Andrii Loboda, Viktoriia Petrashenko, Wiesław Olechowski, Gianluca Lista, Fabio Meneghin, Sonia Amodio, Anke Bongers, Thomas Ludwig, Yvan Vandenplas
This multi-center prospective randomized controlled trial was a tolerance and safety study investigating the thickener locust bean gum (LBG) in infants with regurgitation, to support the re-evaluation of the safety of LBG in infant formula. The primary objective was to demonstrate that after an 8-week intervention, stool consistency was not inferior (i.e., was not looser or more watery) in infants fed an anti-regurgitation (AR) formula containing LBG vs. the stool consistency of infants fed with an unthickened control formula...
March 20, 2024: Nutrients
https://read.qxmd.com/read/38541696/an-overview-of-the-possible-exposure-of-infants-to-microplastics
#5
REVIEW
Csilla Mišľanová, Martina Valachovičová, Zuzana Slezáková
Microplastics are small plastic pieces with sizes less than 5 mm. They are becoming a global concern due to the potential risk to human health. The potential risks of microplastics may be greater for infants because they do not have sufficiently developed metabolizing enzymes, have less ability to remove microplastics, and have highly sensitive target organs. Infants should be breastfed for the first six months of life. Breast milk is considered to be the most complete and suitable source of nutrition. However, if breastfeeding during this period is not possible, it is necessary to use formulas designed for infant initial feeding...
March 12, 2024: Life
https://read.qxmd.com/read/38541296/australian-women-s-experiences-of-establishing-breastfeeding-after-caesarean-birth
#6
JOURNAL ARTICLE
Sharon L Perrella, Sarah G Abelha, Philip Vlaskovsky, Jacki L McEachran, Stuart A Prosser, Donna T Geddes
Breastfeeding exclusivity and duration rates are lower after caesarean birth, yet the factors contributing to these are not well understood. This mixed-methods study used an anonymous online questionnaire to examine the facilitators and barriers to establishing breastfeeding as identified by Australian women after a caesarean birth. Quantitative data were reported using descriptive statistics, and multivariable models were used to determine the factors associated with breastfeeding outcomes including the timing of breastfeeding initiation, birth experience, and commercial infant formula use...
March 3, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38540861/diverse-genotypes-of-cronobacter-spp-associated-with-dairy-farm-systems-in-jiangsu-and-shandong-provinces-in-china
#7
JOURNAL ARTICLE
Hui Liu, Xing Ji, Haichang Sun, Craig Billington, Xiang Hou, Abbas Soleimani-Delfan, Ran Wang, Heye Wang, Lili Zhang
Cronobacter spp. are the most concerning foodborne pathogen in infant formula milk powder. Currently, there are many reports on the prevalence of Cronobacter spp. in infant formula milk and its processing environment, but there are few studies on the prevalence of Cronobacter spp. on dairy farms. We have, therefore, undertaken this study to investigate and track genomic epidemiology of Cronobacter spp. isolates from Chinese dairy farms in the provinces of Jiangsu and Shandong. In this study, forty Cronobacter spp...
March 13, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38540644/pollutants-in-breast-milk-a-scoping-review-of-the-most-recent-data-in-2024
#8
REVIEW
Raphaël Serreau, Yasmine Terbeche, Virginie Rigourd
Perinatal exposure to pollutants, including persistent organic pollutants (POPs) and heavy metals, poses significant risks to both mothers and children, marking this period as highly vulnerable. Despite the well-acknowledged benefits of breastfeeding, there exists a gap in comprehensive understanding regarding the impact of environmental pollutants on breast milk, underscoring the critical need for this study. Our research addresses this gap by exploring the intersection of environmental health and lactation, situated within the broader 'One Health' concept, thus contributing a novel perspective to the existing body of knowledge...
March 18, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38540103/maternal-foetal-infant-interactions-gut-microbiota-and-immune-health
#9
REVIEW
Ada Maria Adamczak, Alicja Werblińska, Małgorzata Jamka, Jarosław Walkowiak
In recent years, the number of scientific publications on the role of intestinal microbiota in shaping human health, as well as the occurrence of intestinal dysbiosis in various disease entities, has increased dynamically. However, there is a gap in comprehensively understanding the factors influencing a child's gut microbiota. This review discusses the establishment of gut microbiota and the immunological mechanisms regulating children's microbiota, emphasising the importance of prioritising the development of appropriate gut microbiota in a child from the planning stages of pregnancy...
February 22, 2024: Biomedicines
https://read.qxmd.com/read/38539300/sex-specific-differences-in-nutrient-intake-in-late-preterm-infants
#10
JOURNAL ARTICLE
Pradeep Alur, Sumana Ramarao, Addie Hitt, Simmy Vig, Radha Alur, Naveed Hussain
UNLABELLED: Challenging the assumption of uniform nutritional needs in preterm feeding, this study identifies crucial sex-specific disparities in formula milk intake and growth among late preterm infants. Premature infants have difficulty regulating their oral intake during feeds, which is why clinicians prescribe feeding volume, calories, and protein via the nasogastric route. However, premature male and female infants have different body compositions at birth, and, subsequently, there is no evidence to suggest that male and female preterm infants differ in their nutritional consumption once they begin feeding ad libitum...
February 20, 2024: Children
https://read.qxmd.com/read/38530054/microbiota-from-human-infants-consuming-secretors-or-non-secretors-mothers-milk-impacts-the-gut-and-immune-system-in-mice
#11
JOURNAL ARTICLE
Manoj Gurung, Brent Thomas Schlegel, Dhivyaa Rajasundaram, Renee Fox, Lars Bode, Tianming Yao, Stephen R Lindemann, Tanya LeRoith, Quentin D Read, Christy Simecka, Laura Carroll, Aline Andres, Laxmi Yeruva
UNLABELLED: Maternal secretor status is one of the determinants of human milk oligosaccharides (HMOs) composition, which, in turn, influences the gut microbiota composition of infants. To understand if this change in gut microbiota impacts immune cell composition, intestinal morphology, and gene expression, 21-day-old germ-free C57BL/6 mice were transplanted with fecal microbiota from infants whose mothers were either secretors (SMM) or non-secretors (NSM) or from infants consuming dairy-based formula (MFM)...
March 26, 2024: MSystems
https://read.qxmd.com/read/38529854/infant-formula-ingredients-updates-for-clinicians
#12
JOURNAL ARTICLE
Minna L Rodrigo, Heidi A Tymann, Heidi A Lochen, Darla R Shores
No abstract text is available yet for this article.
March 26, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38526809/alimentation-infantile-et-changements-climatiques%C3%A2-une-opportunit%C3%A3-prometteuse
#13
JOURNAL ARTICLE
Micheline Beaudry, Ray Bustinza, Isabelle Michaud-Létourneau
The method of infant feeding has consequences for the production of greenhouse gases (GHG) as well as for the risks to infants posed by climate change. Breastfeeding can reduce the carbon footprint associated with the use of commercial infant formula by nearly 50% while reducing its water footprint and waste. It is also an excellent way of coping with emergencies associated with climate change, such as water shortages, since breastfed children are better protected than those fed with formula. To ensure that the protection offered by breastfeeding can be realized, we present elements that can help decision-makers seize a promising opportunity: improve infant feeding support for women and families...
March 25, 2024: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://read.qxmd.com/read/38523370/self-reported-history-of-breastfeeding-in-relation-to-recalled-age-at-menarche-in-the-united-states
#14
JOURNAL ARTICLE
Claire L Gold, Elizabeth Bertone-Johnson
Menarche is a key life history event that shapes the female reproductive trajectory and is important to the study of human biology because of the associated epidemiological and social consequences later in life. Our question is whether breastfeeding is associated with the variation in timing of menarche. Using data from a college-aged female student population from Amherst, MA, we examined whether having been breastfed was associated with age at menarche. Of the 340 female participants with information on breastfeeding during infancy, we found that women who were breastfed (n = 286) had an adjusted mean age of menarche of 12...
March 24, 2024: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://read.qxmd.com/read/38520905/human-milk-sphingomyelin-function-metabolism-composition-and-mimicking
#15
REVIEW
Yuying Yuan, Junying Zhao, Qian Liu, Yan Liu, Yan Liu, Xiaoyan Tian, Weicang Qiao, Yanyan Zhao, Yanpin Liu, Lijun Chen
Human milk, which contains various nutrients, is the "gold standard" for infant nutrition. Healthy human milk meets all the nutritional needs of early infant development. Polar lipids mainly exist in the milk fat globule membrane, accounting for approximately 1-2% of human milk lipids; sphingomyelin (SM) accounts for approximately 21-24% of polar lipids. SM plays an important role in promoting the development of the brain and nervous system, regulating intestinal flora, and improving skin barriers. Though SM could be synthesized de novo, SM nutrition from dietary is also important for infants...
March 18, 2024: Food Chemistry
https://read.qxmd.com/read/38519198/optimizing-ara-and-dha-in-infant-formula-a-systematic-review-of-global-trends-regional-disparities-and-considerations-for-precision-nutrition
#16
REVIEW
Xinggang Ni, Zhiyi Zhang, Zeyuan Deng, Jing Li
In the context of precision nutrition, the addition of ARA and DHA in infant formula needs to consider more factors. This study conducted a comprehensive literature review, including 112 relevant Chinese and English articles, to summarize and analyze the global levels of ARA, DHA, and the ARA/DHA ratio in breast milk. The data were correlated with local aquatic products intake and children's IQ. The results indicated that the average level of DHA in breast milk across regions is lower than that of ARA. Variations in DHA content were identified as a primary factor influencing ARA/DHA ratio fluctuations...
April 2024: Food Research International
https://read.qxmd.com/read/38519033/survival-and-expression-of-rpos-and-grxb-of-cronobacter-sakazakii-in-powdered-infant-formula-under-simulated-gastric-conditions-of-newborns
#17
JOURNAL ARTICLE
Devita Kireina, Valeria R Parreira, Lawrence Goodridge, Jeffrey M Farber
Cronobacter sakazakii can cause severe illnesses in infants, predominantly in preterm newborns, with consumption of contaminated powdered infant formula (PIF) being the major vehicle of infection. Using a dynamic human gastrointestinal simulator called the SHIME, this study examined the effects of gastric acidity and gastric digestion time of newborns on the survival and expression of stress genes of C. sakazakii. Individual strains, inoculated at 7 log CFU/mL into reconstituted PIF, were exposed to gastric pH values of 4...
March 20, 2024: Journal of Food Protection
https://read.qxmd.com/read/38517006/compensation-in-neonatal-clinical-trials-a-perspective
#18
JOURNAL ARTICLE
Apoorva Mathur, Dilip Raja, Anju Sinha, Subodh S Gupta, Y K Gupta, Anand S Kawade, Ramesh Poluru
Well conducted clinical trials are the mainstay for generating evidence on preferred treatments. In order to adequately protect the interests of the trial participants, the Central Licensing Authority of India has formulated guidelines to determine the quantum of compensation in cases of regulatory clinical trial related injury or death. However, these guidelines do not address the nuances of trials recruiting children aged under 16 years, within which, neonates are the most vulnerable population. Thus, there is a need for addressing this lacuna in the current guidelines...
March 19, 2024: Indian Pediatrics
https://read.qxmd.com/read/38514864/global-and-regional-prevalence-of-cronobacter-sakazakii-in-powdered-milk-and-flour
#19
JOURNAL ARTICLE
Temitope C Ekundayo, Oluwatosin A Ijabadeniyi
Cronobacter sakazakii (Cz) infections linked with powdered milk/flour (PMF) are on the increase in recent times. The current study aimed at assessing worldwide and regional prevalence of Cz in PMF. Cz-PMF-directed data were conscientiously mined in four mega-databases via topic-field driven PRISMA protocol without any restriction. Bivariate analysis of datasets was conducted and then fitted to random-intercept logistic mixed-effects regressions with leave-one-study-out-cross-validation (LOSOCV). Small-study effects were assayed via Egger's regression tests...
March 22, 2024: Scientific Reports
https://read.qxmd.com/read/38513488/simulated-in-vitro-infant-digestion-and-lipidomic-analysis-to-explore-how-the-milk-fat-globule-membrane-modulates-fat-digestion
#20
JOURNAL ARTICLE
Yue Pan, Yibo Liu, Jiayi Zhao, Liqin Cui, Xiaodong Li, Lu Liu, Kouadio Jean Eric-Parfait Kouame, Zhong Wang, Xin Tan, Yanxi Jiang, Chao Gao
We hypothesized that the addition of milk fat globule membranes (MFGMs) to infant formula would improve its lipolysis, making it more similar to human milk (HM) and superior to commercial infant formula (CIF) in fat digestion. Therefore, we prepared two model infant formulas (MIFs) by adding MFGMs to dairy ingredients in different ways and compared their fat digestion behavior with those of HM and CIF. MFGMs were added alone (MIF1) and with other milk-based materials (MIF2) before homogenization. The addition of MFGMs reduced the flocculation of lipids and proteins in the gastric phase and promoted lipolysis in the intestine phase...
March 13, 2024: Food Chemistry
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