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premature rupture membranes

Veronika Aleksandrovych, Paweł Basta, Krzysztof Gil
Adenomyosis seems to be the most widespread coexistent pathology included under the umbrella of common benign disorders of the human uterus. The incidence of adenomyosis is under discussion since different imaging criteria are used. In the majority of cases, prevalence is determined among women with uterine fibroids and endometriosis or severe gynecological symptoms. This common benign pathology is asymptomatic in 1/3 of cases. Up to 50% of women with infertility are affected by adenomyosis. It seems to be an important risk factor for spontaneous pre-term delivery and pre-term premature rupture of the membranes...
August 7, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Youhei Tsunoda, Takehiko Fukami, Koichi Yoneyama, Ikuno Kawabata, Toshiyuki Takeshita
OBJECTIVE: To examine whether the presence of amniotic fluid sludge (AFS) could increase the risk of preterm delivery in women with a cervical length of less than 25 mm. MATERIALS AND METHODS: This is a retrospective cohort study of 110 women who were 14-30 weeks pregnant with a singleton gestation and a cervical length of less than 25 mm. The primary outcomes were defined as preterm delivery before 34 weeks and preterm delivery before 37 weeks. The secondary outcome was defined as preterm premature rupture of membranes (PPROM) prior to preterm delivery...
August 6, 2018: Journal of Maternal-fetal & Neonatal Medicine
Céline Petit, Philippe Deruelle, Hélène Behal, Thameur Rakza, Sara Balagny, Damien Subtil, Elodie Clouqueur, Charles Garabedian
INTRODUCTION: Home care management offers a suitable alternative option of hospitalization for management of preterm premature rupture of membranes (PPROM). Eligibility criteria have not been clearly established. Our aim was to determine predictive factors of complication during home care management of PPROM, in order to define optimal eligibility criteria. MATERIAL AND METHODS: Retrospective cohort study of all singleton pregnancy with PPROM managed as outpatient between 2009 and 2015...
August 6, 2018: Acta Obstetricia et Gynecologica Scandinavica
Fatma Dursun, Serdar Ceylaner
Aromatase deficiency is a rare autosomal recessive disorder in which affected patients cannot have a normal estrogen synthesis. Herein, we report a 46, XX patient born with virilised external genitalia. A novel homozygous mutation in the CYP19A1 gene, causing aromatase deficiency, was detected. A 30-day infant was referred to pediatric endocrinology because of a uterus, detected in an ultrasonography examination. He was born at 23th gestational week with C-section because of preeclampsia and premature membrane rupture...
August 3, 2018: Journal of Clinical Research in Pediatric Endocrinology
Maha Hussain Alhainiah, Hasan S O Abdulljabbar, Yasir Ahmad Bukhari
Introduction: The incidence of grand multiparty in Saudi Arabia is high; there are no adequate studies about the grand multiparty. Aim: The aim to determine the prevalence, fetal and maternal outcomes in grand multipara women in comparison to primipara's women. Methods: A retrospective study, the data was collected from our hospital records of labour and delivery unit started from January 2016 to December 2016. Results: The analysis was done in 415 charts divided into two group 1 consist of (120 primigravidas) used as the control and group 2 the study group (295 grand multiparas)...
June 2018: Materia Socio-medica
Ruth McCuaig, Diana Wong, Fergus W Gardiner, William Rawlinson, Jane E Dahlstrom, Stephen Robson
INTRODUCTION: Preterm birth is a common cause of adverse neonatal and childhood outcomes. It is commonly associated with infection of the maternal-fetal interface. The relationship between periodontitis and preterm labour is controversial. METHODS: Control placental tissues from uncomplicated term births were compared with those from spontaneous preterm births for incidence of common periodontal bacteria. A chi-square analysis was used to compare the populations, with significance determined at p=<0...
August 2018: Placenta
Nicole Ochsenbein-Kölble, Simone Brandt, Peter Bode, Franziska Krähenmann, Margaret Hüsler, Ueli Möhrlen, Luca Mazzone, Martin Meuli, Roland Zimmermann
INTRODUCTION: Among the risks associated with open fetal surgery, myometrium and fetal membrane issues are vexing problems since they may lead to uterine dehiscence or preterm premature rupture of membranes resulting in uterine rupture or preterm birth or both. The aim of this study was to examine whether stapled and sutured hysterotomy scars demonstrate partial or complete healing. METHODS: Hysterotomy sites after open fetal surgery were clinically evaluated in 36 women during Caesarean section, classified into the categories intact, thin, and partially or completely dehiscent, then completely excised and histologically analyzed in 25 cases...
July 26, 2018: Fetal Diagnosis and Therapy
Sha Huang, Wei Xia, Xia Sheng, Lin Qiu, Bin Zhang, Tian Chen, Shunqing Xu, Yuanyuan Li
OBJECTIVES: Maternal exposure to lead (Pb) has been suggested to correlate with adverse birth outcomes, but evidence supporting an association between Pb exposure and premature rupture of membranes (PROM) is limited. The aim of our study was to investigate whether maternal Pb exposure was associated with PROM and preterm PROM. DESIGN: Cross-sectional cohort study. STUDY POPULATION: The present study involved 7290 pregnant women from the Healthy Baby Cohort in Wuhan, China, during 2012-2014...
July 23, 2018: BMJ Open
Jennifer B Griffin, Lennex Yu, Donna Watson, Nikki Turner, Tony Walls, Anna S Howe, Yannan Jiang, Helen Petousis-Harris
BACKGROUND: New Zealand has funded the administration of tetanus, diphtheria and acellular pertussis (Tdap) vaccine during pregnancy to prevent infant pertussis since 2013. The aim of this study was to assess the safety of Tdap vaccine administered to pregnant women as part of a national maternal immunisation programme. METHODS: We conducted a national retrospective observational study using linked administrative New Zealand datasets. The study population consisted of pregnant women eligible to receive funded Tdap vaccination from 28 to 38 weeks gestation in 2013...
July 18, 2018: Vaccine
Nafiseh Saghafi, Leila Pourali, Kiarash Ghazvini, Asieh Maleki, Mahdis Ghavidel, Mohsen Karbalaeizadeh Babaki
Background: One of the most important etiologies in pretermpremature rupture of membranes (PPROM) is cervical bacterial colonization. Objective: This study evaluated cervical bacterial colonization in women with PPROM and the pregnancy outcomes. Materials and Methods: In this cohort study, 200 pregnant women with PPROM at 27-37 wk of gestation who were admitted in an academic hospital of Mashhad University of Medical Sciences from March 2015 to July 2016 were studied...
May 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
Tuija Hautakangas, Outi Palomäki, Karoliina Eidstø, Heini Huhtala, Jukka Uotila
BACKGROUND: Purpose of this study was to investigate differences between primiparous term pregnancies, one leading to vaginal delivery (VD) and the other to acute cesarean section (CS) due to labor dystocia in the first stage of labor. We particularly wanted to assess the influence of body mass index (BMI) on CS risk. METHODS: A retrospective case-control study in a tertiary delivery unit with 5200 deliveries annually. Cases were 296 term primiparous women whose intended vaginal labor ended in acute CS because of dystocia...
July 18, 2018: BMC Pregnancy and Childbirth
Maurício Mendes Barbosa, Eduardo Félix Martins Santana, Hérbene José Figuinha Milani, Julio Elito Júnior, Edward Araujo Júnior, Antônio Fernandes Moron, Luciano Marcondes Machado Nardozza
Objective: To evaluate the initial maternal and perinatal outcomes of fetoscopic laser photocoagulation for the treatment of twin-to-twin transfusion syndrome (TTTS) in a referral center in Brazil. Methods: This prospective observational study analyzed 24 fetoscopic laser photocoagulation procedures at 18-26 weeks of gestation. TTTS severity was determined using the Quintero classification. Blood vessels that crossed the interamniotic membrane were nonselectively photocoagulated...
July 2018: Obstetrics & Gynecology Science
Annie M Dude, William A Grobman
OBJECTIVE:  The objective of this study was to examine whether a medically indicated preterm delivery is relatively more likely following longer interdelivery intervals. STUDY DESIGN:  This is a case-control study of women with two consecutive deliveries of a live singleton at the same institution between 2005 and 2015, with the subsequent delivery occurring preterm. Preterm deliveries were classified as spontaneous if women delivered following preterm labor, preterm premature rupture of membranes, or placental abruption...
July 17, 2018: American Journal of Perinatology
César H Meller, María E Carducci, José M Ceriani Cernadas, Lucas Otaño
Preterm premature rupture of membranes occurs in around 3% of pregnancies, and several aspects related to its management are still controversial. The objective of this update is to provide a detailed review of strategies aimed at reducing morbidity and mortality associated with this maternal condition. We will discuss the available evidence regarding the maternal use of antibiotics, the use of corticosteroids according to gestational age, the use of magnesium sulphate for fetal neuroprotection, the use of tocolytic agents, and the best moment for and route of delivery...
August 1, 2018: Archivos Argentinos de Pediatría
Alexis Bonfim-Melo, Eden R Ferreira, Pilar T V Florentino, Renato A Mortara
To complete its life cycle within the mammalian host, Trypanosoma cruzi , the agent of Chagas' disease, must enter cells. Trypomastigotes originating from the insect vector (metacyclic) or from infected cells (bloodstream/tissue culture-derived) are the classical infective forms of the parasite and enter mammalian cells in an actin-independent manner. By contrast, amastigotes originating from the premature rupture of infected cells or transformed from swimming trypomastigotes (designated extracellular amastigotes, EAs) require functional intact microfilaments to invade non-phagocytic host cells...
2018: Frontiers in Microbiology
Sabiniano Roman, Christopher Hillary, Brenda Narice, Anthony J Bullock, Dilly Oc Anumba, Sheila MacNeil
Preterm premature rupture of fetal membranes is a leading cause of preterm delivery. Preterm labour can compromise fetal survival, and even if a pregnancy affected by preterm premature rupture of fetal membrane continues, major complications associated with leakage of amniotic fluid and risk of infection can affect the normal development and survival of the baby. There are limited management options for preterm premature rupture of fetal membrane other than delivery of the baby if ascending infection (chorioamnionitis) is suspected...
January 1, 2018: Journal of Biomaterials Applications
Seung Mi Lee, Kyo Hoon Park, Eun Young Jung, Song Yi Kook, Hyunsoo Park, Se Jeong Jeon
OBJECTIVE: We aimed to assess the correlations among multiple cytokine concentrations in the maternal plasma, cervicovaginal fluid (CVF), and amniotic fluid (AF) compartments in women with preterm premature rupture of membranes (pPROM), and to develop a prediction model based on non-invasive measures, having better sensitivity and specificity for the identification of microbial invasion of amniotic cavity (MIAC). METHOD: This retrospective study included 75 consecutive women with pPROM (20+0-34+0 weeks), who underwent amniocentesis...
2018: PloS One
Geum Joon Cho, Yung-Taek Ouh, Log Young Kim, Tae-Seon Lee, Geun U Park, Ki Hoon Ahn, Soon-Cheol Hong, Min-Jeong Oh, Hai-Joong Kim
BACKGROUND: The aim of this study was to determine the effect of cerclage in women who underwent cervical conization. METHODS: Study data were collected from the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service for 2009-2013. Women who had a conization in 2009 and a subsequent first delivery between 2009 and 2013 in Korea were enrolled. RESULTS: Among the women who had conization in 2009, 1075 women had their first delivery between 2009 and 2013...
July 3, 2018: BMC Pregnancy and Childbirth
Geneviève Genest, Karen A Spitzer, Carl A Laskin
OBJECTIVE: Tumor necrosis factor inhibitors (TNFi) are increasingly used in pregnancy but are frequently withheld in the second or third trimesters. We evaluated the maternal and fetal outcomes of women who continued their TNFi throughout pregnancy compared to women who interrupted TNFi during pregnancy. METHODS: We retrospectively analyzed the outcomes of women seen in clinic with rheumatoid arthritis (RA), psoriatic arthritis, juvenile idiopathic arthritis (JIA), or ankylosing spondylitis, who were exposed to TNFi during pregnancy...
July 1, 2018: Journal of Rheumatology
Ioannis Tsakiridis, Apostolos Mamopoulos, Eleni-Markella Chalkia-Prapa, Apostolos Athanasiadis, Themistoklis Dagklis
Importance: Preterm premature rupture of membranes (PPROM) is a major cause of perinatal mortality and morbidity. Objective: The aim of this study was to compare recommendations from published national guidelines for pregnancies complicated with PPROM. Evidence Acquisition: A descriptive review of 3 national guidelines on PPROM was performed: the Royal College of Obstetricians and Gynaecologists on "Preterm Prelabour Rupture of Membranes," the American College of Obstetricians and Gynecologists on "Premature Rupture of Membranes," and the Society of Obstetricians and Gynaecologists of Canada on "Antibiotic Therapy in Preterm Premature Rupture of the Membranes...
June 2018: Obstetrical & Gynecological Survey
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