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premature rupture membranes

Jean-Charles Pasquier, Olivier Claris, Muriel Rabilloud, René Ecochard, Jean-Charles Picaud, Stéphanie Moret, Danielle Buch, Georges Mellier
OBJECTIVES: Preterm premature rupture of fetal membranes (PPROM) exposes the fetus to preterm birth, and optimal timing for delivery is controversial. The aim of this study was to compare intentional early delivery ("active management") with expectant management in very preterm birth (28-32 weeks). STUDY DESIGN: We conducted a prospective randomized controlled trial with intent-to-treat analysis, at 19 tertiary-care hospitals in France and 1 in Geneva, Switzerland...
December 5, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Kartik K Venkatesh, Kelly K Ferguson, Nicole A Smith, David E Cantonwine, Thomas F McElrath
OBJECTIVE:  To estimate the association between antenatal depression and spontaneous preterm birth (SPTB) relative to medically indicated preterm birth (MPTB). STUDY DESIGN:  This was a secondary analysis of a nested case-control study of preterm birth (PTB). The exposure was a clinical diagnosis of antenatal depression. The outcome was PTB at <37 weeks classified as SPTB (spontaneous labor, preterm premature rupture of membranes, placental abruption, and cervical shortening); and MPTB (preeclampsia and intrauterine growth restriction)...
December 14, 2018: American Journal of Perinatology
Rebecca J Baer, Christina D Chambers, Kelli K Ryckman, Scott P Oltman, Larry Rand, Laura L Jelliffe-Pawlowski
We examined the association between gastroschisis and preterm birth (PTB, <37 weeks) by subtype. The sample was drawn from singleton live births in California from 2007 to 2012 contained in a birth cohort file maintained by the California Office of Statewide Health Planning and Development (n = 2,891,965; 1,421 with gastroschisis). Relative risks (RRs) and 95% confidence intervals (CIs) were calculated for PTB by gestational age (<34, 34-36, and any <37 weeks) and by type (spontaneous labor with intact membranes, preterm premature rupture of the membranes [PPROM], provider initiated) and were adjusted for maternal characteristics...
December 14, 2018: American Journal of Medical Genetics. Part A
Min Jiang, Miskatul Mustafa Mishu, Dan Lu, Xianghua Yin
OBJECTIVE: The aim is to examine risk factors and neonatal outcomes of preterm birth and to provide basis in preventing preterm birth. MATERIALS AND METHODS: we carried out our study on 1328 term controls and 1328 preterm birth cases. By using multivariable logistic regression procedures we estimated odds ratio (OR) of potential preterm birth risk factors. T-test and chi-square test were used to estimate differences between groups. RESULTS: Maternal age, prior history of pregnancy and abortion, prenatal care, complications of pregnancy (includes hypertension, intrahepatic cholestasis of pregnancy (ICP), fetal growth restriction (FGR), premature rupture of the membranes (PROM), placenta previa, abnormal presentation, abnormal S/D ratio et al...
December 2018: Taiwanese Journal of Obstetrics & Gynecology
Isabelle Monier, Nathalie Lelong, Pierre-Yves Ancel, Alexandra Benachi, Babak Khoshnood, Jennifer Zeitlin, Béatrice Blondel
OBJECTIVE: To estimate the prevalence and indications of terminations of pregnancy (TOP) between 22+0 and 31+6 weeks of gestational age in France and to examine the characteristics of women by indication of TOP. STUDY DESIGN: From the EPIPAGE 2 population-based cohort study of preterm births in France in 2011, we selected 5009 singleton live births, stillbirths and TOP that occurred between 22 and 31 weeks. We estimated the proportion of TOP by gestational age. We then classified terminations by indications into 4 categories: fetal anomalies (TOPFA), preterm premature rupture of the membranes (PPROM), maternal conditions and fetal growth restriction (FGR)...
December 3, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Silvina E Cocucci, Mirtha G Santacruz Silvero, Mirta O Losada, María S Touzón, Hilda RudaVega, Manuel Vazquez Blanco, Sergio L Provenzano, Carlos A Vay, Ángela M R Famiglietti, Beatriz E Perazzi
The etiology leading to neonatal damage is multifactorial, being genital infections one of the causes. The objective of the study was to identify microorganisms of the maternal genital tract that are associated with neonatal damage, in order to prevent future perinatal complications. Seven hundred and eleven pregnant patients attended their prenatal control during the period January 2010-July 2013. Ureaplasma urealyticum and Mycoplasma hominis presence was investigated in umbilical cord blood by metabolic substrates (Micofast-Biomerieux) and that of T...
December 9, 2018: Revista Argentina de Microbiología
Tsehaynesh Aslake Wendmagegn, Gerezgiher Buruh Abera, Weyzer Tilahun Tsehaye, Kibrom Brhanu Gebresslasie, Berhe Girmay Tella
BACKGROUND: Surgical site infection (SSI) is an infection that occurs after surgery within 30 days in the part of the body where the surgery took place. Some of the common symptoms are: drainage of cloudy fluid from the surgical wound, pain or tenderness, localized swelling, redness, and raised body temperature. Lack of data on surgical site infection among women who underwent cesarean section (C/S) initiated us to undertake this paper which is targeted to assess the magnitude and determinants of SSI among women who underwent cesarean section...
December 12, 2018: BMC Pregnancy and Childbirth
Stefania Ronzoni, Valerie Steckle, Rohan D'Souza, Kellie E Murphy, Stephen Lye, Oksana Shynlova
Premature prelabor rupture of the membranes (PPROM) causes one-third of preterm births worldwide and is most likely caused by subclinical intrauterine infection and/or inflammation. We proposed that women with systemic inflammation at the time of PPROM would have shorter latency. Peripheral blood samples were collected from 20 singleton pregnant women with PPROM between 23 ± 1 and 33 ± 6 weeks. The first sample was drawn within 48 hours of admission, followed by weekly blood draws until delivery. Pregnancies complicated with acute chorioamnionitis, preeclampsia, intrauterine growth restriction, obesity, substance abuse, and chronic maternal disease were excluded...
December 12, 2018: Reproductive Sciences
Joanna Mader, Catherine Craig
We discuss the management of GBS positive women with PPROM, an aspect of obstetrical management that remains controversial despite the publication of new randomized control trials in recent years. Clinical practice guidelines from several countries' national organizations are compared and contrasted, and areas of uncertainty are identified.
December 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Phatsorn Sae-Lin, Prapat Wanitpongpan
AIM: To obtain the incidence of preterm premature rupture of membranes (PPROM) at Siriraj Hospital during 2012-2016 and to identify its possible risk factors in singleton pregnancies. METHODS: This study was a retrospective case-control study. The institutional ethical committee has approved the study. The medical records of eligible cases were reviewed. To assess the risk factors of PPROM, the data of the cases with PPROM in 2016 were compared with the data of pregnant women who did not have PPROM and delivered at term...
December 11, 2018: Journal of Obstetrics and Gynaecology Research
Ketut Surya Negara, Ketut Suwiyoga, Tjokorda Gede Astawa Pemayun, Anak Agung Raka Sudewi, Nyoman Mantik Astawa, I Gusti Nyoman Kamasan Arijana, Ketut Tunas
OBJECTIVE:  To determine the role of caspase-3, apoptosis-inducing factor (AIF), and B-cell lymphoma-2 (Bcl-2) expressions in term premature rupture of membrane (PROM). METHODS:  An analytic observational study with case-control design was conducted, involving 52 subjects (37-42 weeks of gestation) who were divided into 2 groups: 26 cases of term delivery with PROM, and 26 controls of term delivery without PROM. The expressions of caspase-3, AIF, and Bcl-2 in the amniotic membrane were determined by immunohistochemistry...
December 2018: Revista Brasileira de Ginecologia e Obstetrícia
Marcela López-Hurtado, Selene García-Romero, Marcos R Escobedo-Guerra, David Bustos-López, Fernando M Guerra-Infante
BACKGROUND: Endocervical infection by Chlamydia trachomatis is considered one of the leading causes of infertility worldwide. During pregnancy, it can lead to serious complications such as premature rupture of membranes and premature births. AIM: To determine the prevalence of genital infection by C. trachomatis in pregnancy and infertile women from Mexico City. METHODS: The detection of C. trachomatis was performed by real-time PCR with the commercial kit COBAS® TaqMan CT Test v2...
August 2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
Fábio Gonçalves Coutinho, Edna Maria de Albuquerque Diniz, Ingrid Kandler, Marco Antônio Cianciarullo, Natália Rodrigues Dos Santos
BACKGROUND: To determine the concentration of the Lipid Peroxidation Marker: Malondialdehyde (MDA), and Antioxidant Markers: Superoxide Dismutase (SOD), Glutathione Peroxidase (GPX), Catalase (CAL) in umbilical cord blood and in unstimulated saliva in the first 24 and 48 hours of life in the PTNB of mothers with and without risk factors for early-onset neonatal sepsis. METHODS: Cross-sectional study with the signing of informed consent by the pregnant women and application of a standard questionnaire classifying the PTNB in Group 1 or 2...
October 2018: Revista da Associação Médica Brasileira
Anis Haddad, Olfa Zoukar, Houda Mhabrich, Awatef Hajjeji, Raja Faleh
In recent years, the incidence of placenta accreta and associated complications has increased significantly. The authors report the case of a pregnant woman in the 5th month of pregnancy for premature rupture of the membranes. The placenta was inserted low. The evolution was marked spontaneous work followed by the expulsion of the fetus. The delivery of the placenta was haemorrhagic and incomplete. Ultrasonic testing showed a placental fragment integrated in the thickness of the myometrium. Conservative treatment with methotrexate was published a few days later and MRI showed that the anterior uterine sac was filled with blood clots associated with pelvic effusion...
2018: Case Reports in Obstetrics and Gynecology
Lisa M Vallely, Dianne Egli-Gany, William Pomat, Caroline Se Homer, Rebecca Guy, Handan Wand, Bronwyn Silver, Alice R Rumbold, John M Kaldor, Nicola Low, Andrew J Vallely
INTRODUCTION: Several bacterial sexually transmitted and genital mycoplasma infections during pregnancy have been associated with poor pregnancy and perinatal outcomes. Comprehensive and systematic information about associations between sexually transmitted infections (STI) and genital infections in pregnancy and adverse perinatal outcomes is needed to improve understanding about the evidence for causal associations between these infections and adverse pregnancy and neonatal outcomes...
November 28, 2018: BMJ Open
M N Tarana, S M Shamsuzzaman
Pathogenic microorganisms are important cause of maternal and neonatal infections which are transmitted from colonized vagina of mother. The purpose of the present study was to detect the potential pathogens other than Group B Streptococcus in vaginal swab of pregnant women. This prospective cross sectional study was conducted from July 2013 to June 2014 at Dhaka Medical College Hospital, Dhaka, Bangladesh. A total of 224 vaginal swab samples were studied. Gram stain Nugent score was applied for all vaginal smear to detect bacterial vaginosis...
October 2018: Mymensingh Medical Journal: MMJ
Lei Hou, Xin Wang, Susan Hellerstein, Liying Zou, Yan Ruan, Weiyuan Zhang
OBJECTIVE: The purpose of this study is to assess the incidence of oligohydramnios at term and evaluate whether mode of delivery in patients with oligohydramnios influences perinatal outcomes in China. METHODS: A cross sectional survey of all deliveries in 39 hospitals in China from 1 January to 31 December, 2011 was evaluated for mode of delivery and perinatal outcomes in women with oligohydramnios compared to those without known oligohydramnios after excluding preterm births, polyhydramnios, and oligohydramnios secondary to premature rupture of membranes...
November 28, 2018: Journal of Maternal-fetal & Neonatal Medicine
Cha Han, Huiyang Li, Lulu Han, Chen Wang, Ye Yan, Wenhui Qi, Aiping Fan, Yingmei Wang, Fengxia Xue
The purpose of this study was to investigate the risk factors and pregnancy outcomes for aerobic vaginitis (AV) in late pregnancy. A total of 624 pregnant women who were treated in the perinatal unit at Tianjin Medical University General Hospital and 365 nonpregnant women who were evaluated at a health management center from January 2015 to June 2016 were recruited for this case-control study. A questionnaire covering personal hygiene habits and sociodemographic factors was administered to pregnant women to analyze risk factors for AV...
November 22, 2018: European Journal of Clinical Microbiology & Infectious Diseases
Clémentine Sciard, Sophie Collardeau-Frachon, Anthony Atallah, Danièle Combourieu, Jérôme Massardier, Sophie Heissat, Pascal Gaucherand, Laurent Guibaud, Mona Massoud
We report prenatal imaging features of four cases of neonatal hemochromatosis due to an alloimmune disease. All cases exhibited intra uterine growth restriction (IUGR) without arguments for a vascular etiology, associated with oligohydramnios. Placental hydrops was present in 75% of cases. Splenomegaly was identified in one case. Other causes of NH have been ruled out during diagnostic workup including karyotype, detection of IGFBP-1 to evaluate a premature rupture of membranes, maternal serologic tests. MRI was performed in two cases and showed an atrophic liver associated with a low signal intensity on T2-sequence in one case...
November 19, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Azadeh Memarian, Seyed Hossein Moosavinezhad Baboli, Nahid Dadashzadeh Asl
Head trauma may occur during delivery and can lead to a number of conditions. When an infant is injured during birth, the cause of injury is generally due to mechanical forces, such as compression, excessive or abnormal traction during delivery, and the use of forceps. A 39-year-old woman who was a primagravida (first pregnancy) with a gestational age of 26 weeks premature pregnancy was referred to a hospital in Tehran due to premature rupture of membranes (PROM) and fever. She arrived 2 h after rupture (noting that the rupture lasted for one week and then the baby was delivered)...
November 22, 2018: Medico-legal Journal
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