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Hisako Hara, Makoto Mihara
BACKGROUND: Detecting more number of functional lymphatic vessels is the essential point in lymphaticovenous anastomosis (LVA). The purpose of this prospective study was to elucidate the efficacy of multi-area injection in indocyanine green (ICG) lymphography in LVA. METHODS: We injected ICG into the first web spaces of the feet or the second web space of the hands, subcutaneously. In multi-area injection group, we injected additional ICG in other areas. We determined the incision design of LVA on the line at about 5 cm distal to dermal backflow point...
December 3, 2018: Microsurgery
Kosuke Ishikawa, Taku Maeda, Emi Funayama, Toshihiko Hayashi, Naoki Murao, Masayuki Osawa, Hiroshi Furukawa, Akihiko Oyama, Yuhei Yamamoto
PURPOSE: Vascularized lymph node transfer is becoming more common in the treatment of lymphedema, but suitable small animal models for research are lacking. Here, we evaluated the feasibility of pedicled vascularized inguinal lymph node transfer in mice. METHODS: Twenty-five mice were used in the study. An inguinal lymph node-bearing flap with a vascular pedicle containing the superficial caudal epigastric vessels was transferred into the ipsilateral popliteal fossa after excision of the popliteal lymph node...
December 3, 2018: Microsurgery
Hiroshi Ashiba, Ryohei Nakayama
Sentinel lymph node (SLN) biopsy for evaluating lymph node metastasis during breast cancer surgery is associated with several problems, such as the consequent increase in operation time and the possibility of abrupt changes in the treatment plan during the operation. Although it is desirable to distinguish SLNs with and without cancer metastasis before surgery, there is no established examination for this purpose. This study aimed to develop a computerized scheme for evaluating metastasis in SLNs by analyzing computed tomography lymphography images and the three-dimensional versions of these images...
November 29, 2018: Radiological Physics and Technology
Amit Goyal
The 'standard of care' method for sentinel node mapping is the combination technique using radioisotope and blue dye although some centres use radioisotope or blue dye alone. Radioisotope usage requires licensing, has regulatory issues around handling and disposal of waste, and logistically may be unavailable or difficult to implement in some centres or less developed country. This has led to the development of alternative methods such as superparamagnetic iron oxide (SPIO), fluorescence techniques using indocyanine green (ICG) or fluorescein, computed tomography lymphography, and contrast-enhanced ultrasound scan (CEUS) using microbubbles...
October 2018: Breast Care
Corinne Becker, Lionel Arrivé, Giuseppe Mangiameli, Ciprian Pricopi, Fanomezantsoa Randrianambinina, Francoise Le Pimpec-Barthes
Post-traumatic localized hand lymphedema is a rare situation and its diagnosis may be difficult, causing lack of care leading to failure of care. Our case study is of two young women with massive post-traumatic hand lymphedema who were treated for algodystrophy for 2 years, and whose bandages and physiotherapy were unsuccessful. Major social and psychological consequences due to difficulty with diagnosis and management resulting in inappropriate tests and therapeutic treatment were prescribed due to these issues...
2018: SICOT-J
Hiroo Suami, Louise Koelmeyer, Helen Mackie, John Boyages
Upper extremity lymphoedema after axillary node dissection is an iatrogenic disease particularly associated with treatment for breast or skin cancer. Anatomical studies and lymphangiography in healthy subjects identified that axillary node dissection removes a segment of the lymphatic drainage pathway running from the upper limb to the sub-clavicular vein, creating a surgical break. It is reasonable to infer that different patterns of lymphatic drainage may occur in the upper limb following surgery and contribute to the various presentations of lymphoedema from none to severe...
December 2018: Surgical Oncology
Yushi Suzuki, Hisashi Sakuma, Shun Yamazaki
OBJECTIVE: Lymphaticovenous anastomosis (LVA) is one of the surgical treatments for lymphedema. Lymphaticovenous side-to-end anastomosis (LVSEA) and lymphaticovenous end-to-end anastomosis (LVEEA) are the most commonly used procedures; however, only a few reports have evaluated direct anastomosis. We used indocyanine green fluorescence lymphography to evaluate and to compare both techniques. METHODS: Eighteen patients (67 anastomoses) with secondary upper extremity lymphedema were evaluated 6 months postoperatively...
November 12, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
In Gyu Kwon, Taeil Son, Hyoung-Il Kim, Woo Jin Hyung
Importance: Fluorescent imaging with indocyanine green can be used to visualize lymphatics. Peritumoral injection of indocyanine green may allow for visualization of every draining lymph node from a primary lesion on near-infrared imaging. Objectives: To evaluate the role of fluorescent lymphography using near-infrared imaging as an intraoperative tool for achieving complete lymph node dissection and compare the number of lymph nodes retrieved with the use of near-infrared imaging and the number of lymph nodes retrieved without the use of near-infrared imaging...
November 14, 2018: JAMA Surgery
Marco G Patti, Francisco Schlottmann, Marco Di Corpo
No abstract text is available yet for this article.
November 14, 2018: JAMA Surgery
Christopher J Coroneos, Franklin C Wong, Sarah M DeSnyder, Simona F Shaitelman, Mark V Schaverien
BACKGROUND: Bioimpedance spectroscopy (BIS) is an established tool for the measurement of extracellular fluid in lymphedema. This study assesses the validity of BIS measurements using the l-Dex® for evaluating the effectiveness of interventions to treat lymphedema. Measurements are correlated with limb volume, assessment of pitting edema, physiologic measures of lymphatic function, and response to surgical intervention. Three l-Dex BIS metrics are compared. METHODS AND RESULTS: This retrospective study of prospectively collected data identified consecutive patients with lymphedema...
November 2, 2018: Lymphatic Research and Biology
T Aung, C Taeger, S Geis, D Schiltz, E Brix, C Wenzel, P Lamby, A Kehrer, L Prantl, V Brebant
INTRODUCTION: Supermicrosurgical lymphaticovenular anastomosis (LVA) toward becoming a treatment alternative for treatment and for surgical management of refractory lymphedema. Effective LVA requires supermicrosurgical systems to detect and anastomose lymphatic vessels, as they have a small vessel gauge measuring less than 0.5 mm. METHOD: The antro- and retrograd deep LVAs were performed with the combination of superior-edge-of-the-knee incision method and ventral ankle joint incision method...
October 15, 2018: Clinical Hemorheology and Microcirculation
Hayato Konno, Yoshihiro Minamiya
Many researchers have reported that the sentinel node (SN) theory has been established for lung cancer. However, sentinel node navigation surgery (SNNS) has not yet become a routine medical procedure in lung cancer surgery. SN identification is important for efficient retrieval of micrometastases. Methods for identifying SNs include the dye method and the radioisotope (RI) method, but methods such as the indocyanine green (ICG) method, computed tomographic lymphography (CTLG), and the magnetic method are also being studied...
September 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Kei Takase
Recent introduction of multidetector-row computed tomography(MDCT) with more than 64 scanners enabled high-speed scanning in wide range of the body. Electrocardiogram (ECG) gated scanning and 4-dimensional imaging provides precise evaluation of cardiac and vascular diseases. Fine vascular structures such as the artery of Adamkiewicz can be visualized due to improved spatial and temporal resolution of CT and magnetic resonance imaging(MRI). Interventional radiology also plays important roles in combination with surgical treatment...
September 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Yukio Seki, Akiyoshi Kajikawa, Takumi Yamamoto, Takayuki Takeuchi, Takahiro Terashima, Norimitsu Kurogi
BACKGROUND: Lymphaticovenular anastomosis (LVA) is generally an effective procedure for breast cancer treatment-related upper extremity lymphedema (UEL). Clinical improvement is, however, limited by the degree of sclerosis of the lymphatic vessels. We have developed a method by which we use dynamic ultrasonography to depict vessels through which lymph can be propelled into the LVA under the power of the patient's natural hand movements. METHODS: We assessed the dynamic-LVA method by comparing clinical details of 15 cases of breast cancer treatment-related lymphedema treated by dynamic LVA and 15 corresponding cases treated by conventional LVA...
September 20, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Marzanna T Zaleska, Waldemar L Olszewski
BACKGROUND: Evaluation of intermittent pneumatic compression (IPC) in lymphedema is classically based on measurements of circumferences and volume of the edematous limb. However, although important, it provides only a general information without insight into what proceeds under the skin with respect to hydromechanical and structural changes. AIM AND METHODS: We present the multimodal evaluation of the effectiveness of IPC device in limb edema by measuring tissue stiffness, fluid pressure, and flow volume, and lymphoscintigraphic and near-infrared fluorescence (NIRF) indocyanine green (ICG) lymphography imaging of edema fluid movement, before and after one 45-60 minute compression cycle in over 50 patients with lymphedema stage II and III...
October 3, 2018: Lymphatic Research and Biology
Lionel Arrivé, Corinne Becker
No abstract text is available yet for this article.
October 2018: Plastic and Reconstructive Surgery
Hidehiko Yoshimatsu, Takumi Yamamoto, Kenta Tanakura, Yuma Fuse, Akitatsu Hayashi
No abstract text is available yet for this article.
October 2018: Plastic and Reconstructive Surgery
Johannes Grüntzig, Frank Hollmann
Due to its accessible position and tissue heterogeneity, the eye is ideally suited for studying the lymphatic system. As early as the 19th century, questions about the origin and function of this system were discussed. For example, whether Schlemm's canal, which is of particular importance in the pathogenesis of glaucoma, is a lymphatic vessel, or does this vascular system begin with finger-shaped protuberances? Despite the discovery of lymphatic endothelial molecules and the use of molecular imaging technologies, these questions are still discussed controversially today...
September 18, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
Jian Dong, Wenbin Shen, Rengui Wang
No abstract text is available yet for this article.
October 2018: AJR. American Journal of Roentgenology
Lionel Arrivé, Laurence Monnier-Cholley, Sanaâ El Mouhadi
No abstract text is available yet for this article.
October 2018: AJR. American Journal of Roentgenology
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