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https://www.readbyqxmd.com/read/29996998/fragmented-qrs-complexes-after-acute-myocardial-infarction-are-independently-associated-with-unfavorable-left-ventricular-remodeling
#1
Derek S Chew, Stephen B Wilton, Katherine Kavanagh, Haris M Vaid, Danielle A Southern, Linda Ellis, Andrew G Howarth, James A White, Derek V Exner
BACKGROUND: Recovery of left ventricular ejection fraction (LVEF) after acute myocardial infarction (MI) is not universal and is difficult to predict. Fragmented QRS (fQRS) complexes are thought to be markers of myocardial scar. We hypothesized that fQRS complexes on 12‑lead surface ECGs during the initial post-MI period would be associated with adverse LV remodeling over the following year. METHODS: Change in LVEF between the early (0-2 month) and later (2-12 month) post-MI periods was assessed in two independent cohorts of post-MI patients with initial LV dysfunction...
July 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29974889/fragmented-qrs-fqrs-complex-predicts-adverse-cardiac-events-of-st-segment-elevation-myocardial-infarction-patients-undergoing-percutaneous-coronary-intervention-and-thrombolysis
#2
Wei Xia, Xiao-Yan Feng
BACKGROUND ST-segment elevation myocardial infarction (STEMI) is an acute and life-threatening disease. Adverse cardiac events (ACEs) are defined as cardiovascular death or worsening congestive heart failure in STEMI patients. The present study investigated the predictive role of fragmented QRS complex (fQRS) in risks of ACEs in STEMI. MATERIAL AND METHODS This study was a retrospective analysis involving patients who underwent percutaneous coronary intervention (PCI) or thrombolysis. STEMI patients were divided into the fQRS group (259 cases) and the non-fQRS group (161 cases)...
July 5, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29953954/progression-of-electrocardiographic-abnormalities-associated-with-initial-ventricular-fibrillation-in-asymptomatic-patients-with-brugada-syndrome
#3
Hiroshi Morita, Masakazu Miyamoto, Atsuyuki Watanabe, Saori Tsukuda, Yoshimasa Morimoto, Satoshi Kawada, Koji Nakagawa, Nobuhiro Nishii, Hiroshi Ito
BACKGROUND: Various risk stratifications in asymptomatic patients with Brugada syndrome (BrS) have been proposed, but the electrophysiological change that promotes ventricular fibrillation (VF) is still unknown. OBJECTIVE: The aim of this study was to clarify the changes in electrocardiographic (ECG) markers at the onset of VF from ECGs recorded when patients were still asymptomatic. METHODS: The subjects of this study included 14 patients with VF and 48 consecutive asymptomatic patients with BrS...
June 25, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29932268/fragmented-qrs-and-mortality-in-patients-undergoing-percutaneous-intervention-for-st-elevation-myocardial-infarction-systematic-review-and-meta-analysis
#4
Napatt Kanjanahattakij, Pattara Rattanawong, Tanawan Riangwiwat, Narut Prasitlumkum, Nath Limpruttidham, Pakawat Chongsathidkiet, Wasawat Vutthikraivit, Erin Crossey
BACKGROUND: Fragmented QRS reflects disturbances in the myocardium predisposing the heart to ventricular tachyarrhythmias. Recent studies suggest that fragmented QRS (fQRS) is associated with mortality in ST-elevation myocardial infarction (STEMI) patients who underwent percutaneous coronary intervention (PCI). However, a systematic review and meta-analysis of the literature has not been done. We assessed the association between fQRS and overall mortality in STEMI patients who subsequently underwent PCI by a systematic review and meta-analysis...
June 22, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29858880/fragmentation-of-qrs-complex-during-ventricular-pacing-is-associated-with-ventricular-arrhythmic-events-in-patients-with-left-ventricular-dysfunction
#5
Freddy Del-Carpio Munoz, Peter A Noseworthy, S Michael Gharacholou, Christopher G Scott, Vuyisile T Nkomo, Francisco Lopez-Jimenez, Yong-Mei Cha, Thomas M Munger, Paul A Friedman, Samuel J Asirvatham
BACKGROUND: QRS fragmentation (fQRS) during baseline ventricular conduction, a myocardial fibrosis marker, is associated with increased risk of ventricular tachyarrhythmias but may not manifest unless ventricular activation change is provoked. We examined the association of fQRS during right ventricular (RV) pacing with death and ventricular tachyarrhythmia in patients with left ventricular (LV) dysfunction undergoing electrophysiology study (EPS). METHODS AND RESULTS: Study participants had LV dysfunction (ejection fraction < 50%) undergoing EPS from January 2002 to May 2014 at Mayo Clinic in Rochester, Minnesota...
June 2, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29796231/linear-phase-sharp-transition-bpf-to-detect-noninvasive-maternal-and-fetal-heart-rate
#6
Niyan Marchon, Gourish Naik, K R Pai
Fetal heart rate (FHR) detection can be monitored using either direct fetal scalp electrode recording (invasive) or by indirect noninvasive technique. Weeks before delivery, the invasive method poses a risk factor to the fetus, while the latter provides accurate fetal ECG (FECG) information which can help diagnose fetal's well-being. Our technique employs variable order linear phase sharp transition (LPST) FIR band-pass filter which shows improved stopband attenuation at higher filter orders. The fetal frequency fiduciary edges form the band edges of the filter characterized by varying amounts of overlap of maternal ECG (MECG) spectrum...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29776809/the-presence-of-fragmented-qrs-is-associated-with-increased-epicardial-adipose-tissue-and-subclinical-myocardial-dysfunction-in-healthy-individuals
#7
Mehmet Yaman, Ugur Arslan, Adil Bayramoglu, Osman Bektas, Zeki Yuksel Gunaydin, Ahmet Kaya
AIM: The aim of this study was to measure epicardial adipose tissue (EAT) and to assess left ventricular (LV) systolic and diastolic function in a healthy population grouped according to the presence of fragmented QRS (fQRS). METHODS: In this prospective case-control study, the study population consisted of 308 healthy individuals who were divided into two groups according to the existence of fQRS: 180 fQRS(+) individuals (with fQRS), and 128 age- and gender-matched fQRS(-) individuals (without fQRS)...
June 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29759533/12-lead-electrocardiogram-to-localize-region-of-abnormal-electroanatomic-substrate-in-arrhythmogenic-right-ventricular-cardiomyopathy
#8
Cory M Tschabrunn, Haris M Haqqani, Pasquale Santangeli, Erica S Zado, Francis E Marchlinski
OBJECTIVES: The purpose of this study was to evaluate the relationship between electrocardiogram (ECG) QRS fragmentation (fQRS) and right ventricular (RV) endocardial (ENDO) and epicardial (EPI) electroanatomic substrate abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). BACKGROUND: fQRS is frequently observed in patients with ARVC and reflects delayed conduction due to RV fibrosis. METHODS: A total of 30 consecutive patients met the task force criteria for ARVC (19 men, mean age 41...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29732745/combining-fragmented-qrs-and-timi-score-for-predicting-in-hospital-short-term-prognosis-after-acute-myocardial-infarction
#9
Qin-Hui Sheng, Chih Chi Hsu, Jian-Ping Li, Tao Hong, Yong Huo
Acute myocardial infarction (AMI) has a high mortality rate and poor prognosis for patients. The primary causes of death are arrhythmia and heart failure. For patients admitted because of myocardial infarction, various risk evaluations are initiated to foresee possible complications. The thrombolysis in myocardial infarction (TIMI) risk score, which can be used to predict the prognosis and the need for revascularisation, is the most convenient and commonly used system, but is inadequate for AMI patients on admittance...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29728953/electrocardiography-based-prediction-of-hypertrophy-pattern-and-fibrosis-amount-in-hypertrophic-cardiomyopathy-comparative-study-with-cardiac-magnetic-resonance-imaging
#10
Chul Hwan Park, Hyemoon Chung, Yoonjung Kim, Jong-Youn Kim, Pil-Ki Min, Kyung-A Lee, Young Won Yoon, Tae Hoon Kim, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Eui-Young Choi
Although, cardiac magnetic resonance imaging (CMR) is a gold standard for risk stratification of hypertrophic cardiomyopathy (HCM), is limited in some situations. We sought to evaluate the predictive power of quantitative electrocardiography in assessing hypertrophy pattern and fibrosis in HCM. Eighty-eight patients with HCM were studied. Voltage of R-S-T waves, number of fragmented QRS (fQRS) complexes, and T wave morphology were measured by 12-lead electrocardiography. Sixteen segmental thickness, late gadolinium enhancement (LGE), native T1, extracellular volume fraction (ECV), and T2, left ventricular (LV) mass and %LGE were measured by CMR...
May 4, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29709101/genotype-phenotype-relationship-and-risk-stratification-in-loss-of-function-scn5a-mutation-carriers
#11
Tomas Robyns, Dieter Nuyens, Bert Vandenberk, Cuno Kuiperi, Anniek Corveleyn, Jeroen Breckpot, Christophe Garweg, Joris Ector, Rik Willems
INTRODUCTION: Loss-of-function (LoF) mutations in the SCN5A gene cause multiple phenotypes including Brugada Syndrome (BrS) and a diffuse cardiac conduction defect. Markers of increased risk for sudden cardiac death (SCD) in LoF SCN5A mutation carriers are ill defined. We hypothesized that late potentials and fragmented QRS would be more prevalent in SCN5A mutation carriers compared to SCN5A-negative BrS patients and evaluated risk markers for SCD in SCN5A mutation carriers. METHODS: We included all SCN5A loss-of-function mutation carriers and SCN5A-negative BrS patients from our center...
April 30, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29676061/use-of-fragmented-qrs-in-prognosticating-clinical-deterioration-and-mortality-in-pulmonary-embolism-a-meta-analysis
#12
REVIEW
Amro Qaddoura, Geneviève C Digby, Conrad Kabali, Piotr Kukla, Gary Tse, Benedict Glover, Adrian M Baranchuk
BACKGROUND: Fragmented QRS (fQRS) on electrocardiography is potentially valuable in prognosticating acute pulmonary embolism (PE). ECG is one of the first tests performed in the emergency department, quickly interpretable, noninvasive, inexpensive, and available in remote areas. We aimed to review fQRS's role in PE prognostication. METHODS: We searched MEDLINE, EMBASE, Google Scholar, Web of Science, abstracts, conference proceedings, and reference lists until October 2017...
April 19, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29622965/the-relation-between-coronary-artery-disease-severity-and-fragmented-qrs-complex-in-patients-with-left-bundle-branch-block
#13
Mohamed M Al-Daydamony, Tamer M Mustafa
Background: The diagnosis of coronary artery disease (CAD) in patients with LBBB represents a clinical challenge. The presence of fragmented QRS (fQRS) complex on surface ECG may be related to myocardial ischemia, scarring or fibrosis. Objectives: To investigate the relation between fQRS and the presence and severity of CAD in patients with LBBB. Patients and methods: 56 patients with symptoms suggesting CAD and complete LBBB were submitted to full history taking and clinical examination, complete 12-leads electrocardiography (ECG) to confirm the diagnosis of LBBB and to diagnose the fragmented wide QRS (f-wQRS) complex, echocardiography, and coronary angiography; lesions with ⩾70% narrowing in major epicardial artery or ⩾50% narrowing in the left main coronary artery were considered significant; and Gensini score was calculated...
June 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29512627/evaluation-of-the-association-between-serum-uric-acid-level-andthe-predicted-risk-score-of-sudden-cardiac-death-in-five-years-in-patients-with-hypertrophic-cardiomyopathy
#14
Sinem Özyılmaz, Muhammet Hulusi Satılmışoğlu, Mehmet Gül, Hüseyin Uyarel, Osman Akin Serdar
OBJECTIVE: The aim of this study was to determine the relationship between serum uric acid (UA) level and the predicted risk score for sudden cardiac death in 5 years (the HCM Risk-SCD), galectin-3 level, and positive fragmented QRS (fQRS) on electrocardiography (ECG) in patients with hypertrophic cardiomyopathy (HCM). METHODS: This was a prospective, observational study. In all, 115 consecutive patients (age >17 years) with HCM and 80 healthy participants were included in the study...
March 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29375220/relationship-between-fragmented-qrs-and-nt-probnp-in-patients-with-st-elevation-myocardial-infarction-who-underwent-primary-percutaneous-coronary-intervention
#15
Qi Zhao, Ruoxi Zhang, Jingbo Hou, Bo Yu
Background: To investigate the relationship between the presence of fragmented QRS (fQRS) on electrocardiogram (ECG) and plasma NT-proBNP levels in patients with ST-elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). The in-hospital prognostic value of the presence of fQRS was also assessed. Methods: In this retrospective study, 216 patients with STEMI who were undergoing primary PCI were included. fQRS was identified in ECG following primary PCI...
January 2018: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29363882/baseline-fragmented-qrs-increases-the-risk-of-major-arrhythmic-events-in-hypertrophic-cardiomyopathy-systematic-review-and-meta-analysis
#16
Pattara Rattanawong, Tanawan Riangwiwat, Chanavuth Kanitsoraphan, Pakawat Chongsathidkiet, Napatt Kanjanahattakij, Wasawat Vutthikraivit, Eugene H Chung
BACKGROUND: Fragmented QRS reflects disturbances in the myocardium predisposing the heart to ventricular tachyarrhythmias. Recent studies suggest that fragmented QRS (fQRS) is associated with worse major arrhythmic events in hypertrophic cardiomyopathy (HCM). However, a systematic review and meta-analysis of the literature has not been done. We assessed the association between fQRS and major arrhythmic events in hypertrophic cardiomyopathy by a systematic review of the literature and a meta-analysis...
July 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29306465/prognostic-significance-of-qrs-fragmentation-and-correlation-with-infarct-size-in-patients-with-anterior-st-segment-elevation-myocardial-infarction-treated-with-percutaneous-coronary-intervention-insights-from-the-infuse-ami-trial
#17
Björn Redfors, Ioanna Kosmidou, Aaron Crowley, Akiko Maehara, Ori Ben-Yehuda, Arslan Arif, José M Dizon, Gary S Mintz, Gregg W Stone
BACKGROUND: QRS fragmentation (fQRS) is believed to reflect myocardial scar formation in patients with coronary disease. Whether early formation of fQRS in patients with ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) is correlated with infarct size and prognosis is unknown. We assessed the prognostic value of fQRS at 60min post-PCI and its correlation with infarct size in patients with anterior STEMI managed with primary PCI. METHODS: The INFUSE-AMI trial enrolled 452 patients with anterior STEMI undergoing primary PCI...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29275955/inter-and-intra-observer-variability-of-visual-fragmented-qrs-scoring-in-ischemic-and-non-ischemic-cardiomyopathy
#18
Bert Vandenberk, Tomas Robyns, Griet Goovaerts, Mathias Claeys, Frederik Helsen, Sofie Van Soest, Christophe Garweg, Joris Ector, Sabine Van Huffel, Rik Willems
BACKGROUND: Fragmented QRS (fQRS) on a 12-lead ECG has been linked with adverse outcome. However, the visual scoring of ECGs is prone to inter- and intra-observer variability. METHODS: Five observers, two experienced and three novel, assessed fQRS in 712 digital ECGs, 100 were re-evaluated to assess intra-observer variability. Fleiss and Cohen's Kappa were calculated and compared between subgroups. RESULTS: The inter-observer variability for assessing fQRS in all leads combined was substantial with a Kappa of 0...
May 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29240450/letter-in-response-to-tp-e-interval-and-tp-e-qt-ratio-before-and-after-catheter-ablation-in-patients-with-premature-ventricular-complexes
#19
Ahmet Korkmaz, Deniz Sahin, Umit Guray
No abstract text is available yet for this article.
January 2018: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29216794/fragmented-qrs-complexes-are-associated-with-left-ventricular-dysfunction-in-patients-with-type-2-diabetes-mellitus-a-two-dimensional-speckle-tracking-echocardiography-study
#20
Adil Bayramoğlu, Hakan Taşolar, Yasemin Kaya, Osman Bektaş, Ahmet Kaya, Mehmet Yaman, Zeki Yüksel Günaydın
BACKGROUND: Heart failure may develop independently of coronary artery disease in diabetes mellitus (DM) patients. Fragmented QRS (fQRS) is a marker of myocardial fibrosis or scar tissue and is related to an increase in cardiovascular adverse events. In this study, we examined the utility of speckle tracking echocardiography (STE) in assessing LV function in DM patients with fQRS. METHODS AND RESULTS: The current study included 178 consecutive patients diagnosed with type-2 DM...
December 7, 2017: Acta Cardiologica
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