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https://www.readbyqxmd.com/read/30116449/association-of-tp-te-qt-ratio-with-ventricular-tachycardia-in-patients-with-idiopathic-outflow-tract-ventricular-premature-contraction
#1
Arina Prihestri Nugraheni, Irsad Andi Arso, Erika Maharani
Background: Idiopathic outflow tract ventricular premature contraction (VPC) can evolve into ventricular tachycardia (VT) via triggered activity mechanism. Transmural dispersion of repolarization (TDR) might play a role in idiopathic outflow tract VT by inducing phase 2 early afterdepolarization (EAD) and serve as the functional substrate for VT. Tp-Te/QT ratio as an arrhythmogenesis index has been reported to be associated with the incidence of ventricular arrhythmia. This study aims to investigate the association between Tp-Te/QT ratio with VT incidence in idiopathic outflow tract VPC...
August 2018: Cardiology Research
https://www.readbyqxmd.com/read/30102251/parallel-use-of-a-convolutional-neural-network-and-bagged-tree-ensemble-for-the-classification-of-holter-ecg
#2
Filip Plesinger, Petr Nejedly, Ivo Viscor, Josef Halamek, Pavel Jurak
The automated detection of arrhythmia in a Holter ECG signal is a challenging task due to its complex clinical content and data quantity. It is also challenging due to the fact that Holter ECG is usually affected by noise. Such noise may be the result of the regular activity of patients using the Holter ECG - partially unplugged electrodes, short-time disconnections due to movement, or disturbances caused by electric devices or infrastructure. Furthermore, regular patient activities such as movement also affect the ECG signals and, in connection with artificial noise, may render the ECG non-readable or may lead to misinterpretation of the ECG...
August 13, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/30101452/twenty-four-hour-ambulatory-ecg-monitoring-relevancy-in-myotonic-dystrophy-type-1-follow-up-prognostic-value-and-heart-rate-variability-evolution
#3
Alexandre Gamet, Bruno Degand, François Le Gal, Nicolas Bidegain, Anne Delaubier, Brigitte Gilbert-Dussardier, Luc Christiaens, Rodrigue Garcia
BACKGROUND: Patient prognosis in type 1 myotonic dystrophy (DM1) is very poor. Annual 24-hour holter ECG monitoring is recommended but its relevance is debated. Main objective was to determine whether holter ECG parameters could predict global death in DM1 patients and secondarily to assess whether they could predict cardiovascular events and sudden cardiac death, to compare DM1 patients and healthy controls, and to assess their evolution in DM1 over a 5-year period. METHODS: This retrospective study included genetically confirmed DM1...
August 12, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/30088700/effectiveness-comparison-of-various-atrial-fibrillation-ablation-methods-in-patients-with-common-venous-trunk
#4
Edward Koźluk, Dorota Zyśko, Agnieszka Piątkowska, Marek Kiliszek, Piotr Lodziński, Sylwia Małkowska, Paweł Balsam, Dariusz Rodkiewicz, Małgorzata Żukowska, Grzegorz Opolski
BACKGROUND: Atrial fibrillation (AF) is a common clinical problem. The left atrium anatomy makes up a factor that may significantly affect the effectiveness of the AF ablation. OBJECTIVES: The aim of the study was to evaluate a long-term effectiveness ablation in patients with common pulmonary vein trunk (CPVT) and AF. MATERIAL AND METHODS: The outcomes of 129 procedures in 95 patients with CPVT out of 1,475 procedures carried out in 1,150 patients with AF treated with ablation, were analyzed...
August 8, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/30082088/the-43rd-international-society-for-computerized-electrocardiology-ecg-initiative-for-the-automated-detection-of-strict-left-bundle-branch-block
#5
Robbert Zusterzeel, Jose Vicente, Roberto Ochoa-Jimenez, Jun Zhu, Jean-Philippe Couderc, Esther Akinnagbe-Zusterzeel, David G Strauss
The presence of left bundle branch block (LBBB) is an important predictor of benefit from cardiac resynchronization therapy (CRT). New "strict" electrocardiographic (ECG) criteria for LBBB have been shown to better predict benefit from CRT. The "strict" LBBB criteria include: QRS duration ≥140 ms (men) or ≥130 ms (women), QS- or rS-configurations of the QRS complex in leads V1 and V2, and mid-QRS notching or slurring in ≥2 of leads V1, V2, V5, V6, I and aVL. The "strict" LBBB criteria are not regularly used and most hospital automated ECG systems and physicians still use more conventional LBBB criteria...
August 1, 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/30061094/a-novel-12-lead-electrocardiographic-system-for-home-use-development-and-usability-testing
#6
Annemarijn Sm Steijlen, Kaspar Mb Jansen, Armagan Albayrak, Derk O Verschure, Diederik F Van Wijk
BACKGROUND: Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. Early diagnosis is of pivotal importance for patients with cardiac arrhythmias and ischemia to minimize the consequences like strokes and myocardial infarctions. The chance of capturing signals of arrhythmias or ischemia is substantially high when a 12-lead electrocardiogram (ECG) can be recorded at the moment when a patient experiences the symptoms. However, until now, available diagnostic systems (Holter monitors and other wearable ECG sensors) have not enabled patients to record a reliable 12-lead ECG at home...
July 30, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/30061062/bag3-myopathy-is-not-always-associated-with-cardiomyopathy
#7
Annarita Ghosh Andersen, Freja Fornander, Henrik Daa Schrøder, Thomas Krag, Volker Straub, Morten Duno, John Vissing
Bag3opathy is a rare myofibrillar myopathy (MFM) caused by a mutation in the Bcl-2 associated-athanogene-3 gene. Less than twenty patients have been described, almost all with severe cardiac involvement. We present a 26-year-old man with a c.626C>T (p.Pro209Leu) mutation in the Bcl-2 associated-athanogene-3 gene (BAG3). Our patient presented with problems running before he turned 10 and rapidly progressing, proximal muscle weakness and rigidity of the neck and back. Muscle biopsy showed Z-disc streaming, vacuoles, which is typical findings of Bag3opathy, as well as accumulation of filamentous materials...
July 5, 2018: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/30056397/clinical-course-and-treatment-of-children-and-adolescents-with-the-preexcitation-syndrome-own-studies
#8
Aleksandra Stasiak, Katarzyna Niewiadomska-Jarosik, Piotr Kędziora
INTRODUCTION: Essentially, preexcitation syndrome is the presence of an accessory pathway in the heart, which can lead to serious consequences, ranging from atrioventricular reentrant tachycardia to sudden cardiac death. Wolff-Parkinson-White syndrome is the most common preexcitation syndrome. AIM OF THE STUDY: The aim of the study was to evaluate the clinical course of the disease, as well as the treatment of children and adolescents hospitalized in the Department of Pediatric Cardiology in the years 2008-2015...
2018: Developmental Period Medicine
https://www.readbyqxmd.com/read/30056014/interpreting-the-normal-pacemaker-electrocardiograph
#9
REVIEW
Harry G Mond
Modern cardiac pacing systems have sophisticated software to document, evaluate and record intrinsic and paced rhythms as well as correct pacing abnormalities and rhythm disturbances by applying algorithms, which are generally company specific. To the cardiologist and technologist, these algorithms may be difficult to interpret on both the 12-lead electrocardiograph (ECG) and Holter ambulatory monitoring recordings, which are usually performed because of patient symptoms or physician concern. The tracings may appear bewildering and mimic pacemaker malfunction, thus leading to unnecessary tests or even surgery...
July 18, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/30054893/paroxysmal-atrial-fibrillation-detection-in-patients-with-acute-ischemic-stroke-through-prolonged-holter-prospective-study
#10
Mariana Alves, Marco Ribeiro Narciso, João Cruz, Marina Rocha, Teresa Fonseca
INTRODUCTION: The detection of paroxysmal atrial fibrillation (PAF) is crucial in the etiological study of an acute ischemic stroke (AIS), although this type of arrhythmia is often under-diagnosed. This prospective study aims to (1) evaluate the new-onset PAF detection rate among elderly patients with AIS in an acute setting, and (2) to assess the applicability of the STAF score (Score for the Targeting of Atrial Fibrillation) for such patients. METHODOLOGY: An observational and prospective study was performed over a period of 11 months...
July 27, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/30040135/diurnal-profile-of-the-qtc-interval-following-moxifloxacin-administration
#11
Jörg Täubel, Georg Ferber, Sara Fernandes, A John Camm
Understanding the physiological fluctuations in the corrected QT (QTc) interval is important to accurately interpret the variations in drug-induced prolongation. The present study aimed to define the time course of the effect of moxifloxacin on the QT interval to understand the duration of the responses to moxifloxacin. This retrospective analysis was performed on data taken from a thorough QT 4-way crossover study with 40 subjects. Each period consisted of a baseline electrocardiogram (ECG) day (day -1) and a treatment day (day 1)...
July 24, 2018: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/30017817/cardiac-impact-of-r-wave-triggered-irreversible-electroporation-therapy
#12
Michael Kostrzewa, Erol Tueluemen, Boris Rudic, Nils Rathmann, Ibrahim Akin, Thomas Henzler, Volker Liebe, Stefan O Schoenberg, Martin Borggrefe, Steffen J Diehl
BACKGROUND: Irreversible electroporation (IRE) is a novel tumor ablative therapy technique, using electric fields to induce apoptosis in target tissues. It is unclear whether these electric pulses of high field strength can cause cardiac damage and/or ablation induced arrhythmias. OBJECTIVE: To systematically evaluate the safety of ECG gated IRE in regards to cardiac side effects. METHODS: In all patients 12-lead electrocardiogram (ECG), signal-averaged ECG (SAECG) recordings were performed before and after IRE and 24-hour Holter recording on the day of the IRE procedure...
July 12, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/30017203/noninvasive-predictors-of-cardiac-arrhythmias-in-bodybuilders
#13
Kadir Uğur Mert, Serdar İlgüy, Gurbet Özge Mert, Muhammet Dural, Kemal Iskenderov
INTRODUCTION AND OBJECTIVE: Arrhythmias are often recorded in strength training athletes without cardiovascular abnormalities but may also be a sign of an underlying cardiovascular disease which carries a risk of sudden cardiac death (SCD). Nowadays, bodybuilding is a popular sport among adolescents and young adults. There have been few studies of arrhythmias comparing bodybuilders with healthy controls and excluding anabolic steroid use. We aimed to assess the structural, functional and electrical characteristics of bodybuilders' hearts compared with control subjects...
August 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/30010056/what-is-the-real-recurrence-rate-after-cryoballoon-based-pulmonary-vein-isolation-lessons-from-rhythm-follow-up-based-on-implanted-cardiac-devices-with-continuous-atrial-monitoring
#14
Christian-Hendrik Heeger, Verena Tscholl, Omar Salloum, Erik Wissner, Thomas Fink, Laura Rottner, Peter Wohlmuth, Barbara Bellmann, Mattias Roser, Shibu Mathew, Bruno Reißmann, Christine Lemeš, Tilman Maurer, Francesco Santoro, Britta Goldmann, Ulf Landmesser, Feifan Ouyang, Karl-Heinz Kuck, Andreas Rillig, Andreas Metzner
BACKGROUND: Second-generation cryoballoon (CB2)-based pulmonary vein isolation (PVI) has demonstrated encouraging clinical results in the treatment of paroxysmal (PAF) and persistent atrial fibrillation (PersAF). However rhythm follow-up after PVI is mainly based on Holter ECG of limited duration. OBJECTIVE: The aim of this study was to assess the real AF burden following CB2-based PVI in patients with implanted cardiac devices. METHODS: A total of 670 consecutive patients underwent CB2-based PVI in three EP centers...
July 12, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/30005745/imbalance-of-cardiac-autonomic-nervous-activity-and-increase-of-ventricular-repolarization-dynamicity-induced-by-thyroid-hormones-in-hyperthyroidism
#15
Zhongxiang Cai, Mingyan Dai, Yijie Zhang, Hui Zhong, Tuantuan Tan, Mingwei Bao
OBJECTIVE: To investigate the effects of thyroid hormones on cardiac autonomic nervous activity and ventricular repolarization dynamicity in hyperthyroidism. METHODS: 57 consecutive patients first diagnosed of hyperthyroidism (HT group) and 55 age and sex-matched healthy volunteers (Control group) from March 2012 to March 2013 in our center were enrolled. All subjects underwent standard 12‑lead ECG and 24 h Holter recording at baseline. For the HT group, free triiodothyronine (FT3 ), free thyroxine (FT4 ) and thyroid stimulating hormone (TSH) were monitored, and after they returned to normal all the examinations were redone...
September 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29997001/evaluation-of-t-wave-alternans-in-pediatric-patients-with-chronic-renal-failure
#16
Olgu Hallioglu, Meryem Keceli, Gulcin Bozlu, Ali Delibas, Derya Karpuz, Hüseyin Selvi
INTRODUCTION: Microvolt T-wave alternans (TWA) is known to be useful in prediction of ischemia and sudden death in high-risk populations and there are no studies in children with chronic renal failure (CRF). Cardiac problems seem to be responsible for an important part of death in children and young adults with CRF. The aim of this study is to evaluate Holter microvolts TWA measurements in children with CRF comparing to the control group. METHODS: This prospective study included 40 patients with CRF and 48 healthy controls...
July 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29996995/t-wave-alternans-extracted-from-30-minute-short-resting-holter-ecg-recordings-predicts-mortality-in-heart-failure
#17
Petros Arsenos, Konstantinos A Gatzoulis, Polychronis Dilaveris, Skevos Sideris, Dimitrios Tousoulis
BACKGROUND: We extracted T Wave Alternans (TWA) from a 30 minute Short Resting Holter ECG (SRH ECG) in the supine position, as a Total Mortality (TM) predictor in Heart Failure (HF). METHODS: Signals from 146 HF patients (LVEF = 33 ± 10%), were analyzed with Modified Moving Average method. After 42.1 months, 26 patients died. RESULTS: (Deceased vs Living group): TWA:31 ± 18 μV vs 25 ± 13 μV(p = 0.05), LVEF:32 ± 10% vs 34 ± 9% (p = 0...
July 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29995813/autonomic-influences-related-to-frequent-ventricular-premature-beats-in-patients-without-structural-heart-disease
#18
Attila Frigy, Endre Csiki, Cosmin Caraşca, István Adorján Szabó, Victor-Dan Moga
To study the possible role of autonomic influences on the occurrence of frequent premature ventricular beats (VPBs) in subjects without structural heart disease.24-hour Holter ECG recordings (≥1500 VPBs/d, sinus rhythm) of 20 symptomatic patients (9 women, 11 men, mean age 58.9 years) without structural heart disease were used for the study. The circadian distribution pattern of VPBs was studied (paired t test) by dividing the day into 3 periods (16:00-22:00-06:00-16:00), and correlations were analyzed between the absolute (ln transformed) and relative (% of total beats) average hourly numbers of VPBs and the hourly mean values of global and vagal time domain parameters of heart rate variability (Pearson correlation)...
July 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29991415/obstructive-sleep-apnea-in-cardiac-rehabilitation-patients
#19
David Hupin, Vincent Pichot, Mathieu Berger, Emilia Sforza, Jérémy Raffin, Cécile Lietar, Erkan Poyraz, Delphine Maudoux, Jean-Claude Barthelemy, Frédéric Roche
STUDY OBJECTIVES: Although regular physical activity improves obstructive sleep apnea (OSA) in the general population, this finding has not been assessed in postmyocardial infarction (MI) patients in a rehabilitation setting (coronary artery disease, CAD). We aimed to determine whether cardiac rehabilitation may benefit post-MI patients in terms of OSA disease and associated autonomic nervous system (ANS) activity. METHODS: Consecutive post-MI patients participating in the ambulatory cardiac rehabilitation program of St-Etienne University Hospital were included in this study...
July 15, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29974203/an-open-label-multicenter-phase-ib-study-investigating-the-effect-of-apalutamide-on-ventricular-repolarization-in-men-with-castration-resistant-prostate-cancer
#20
Bodine P S I Belderbos, Ronald de Wit, Caly Chien, Anna Mitselos, Peter Hellemans, James Jiao, Margaret K Yu, Gerhardt Attard, Iurie Bulat, W Jeffrey Edenfield, Fred Saad
PURPOSE: Phase Ib study evaluating the effect of apalutamide, at therapeutic exposure, on ventricular repolarization by applying time-matched pharmacokinetics and electrocardiography (ECG) in patients with castration-resistant prostate cancer. Safety of daily apalutamide was also assessed. METHODS: Patients received 240 mg oral apalutamide daily. Time-matched ECGs were collected via continuous 12-lead Holter recording before apalutamide (Day - 1) and on Days 1 and 57 (Cycle 3 Day 1)...
July 5, 2018: Cancer Chemotherapy and Pharmacology
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