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https://www.readbyqxmd.com/read/30264201/acceptance-of-a-new-non-invasive-fetal-monitoring-system-and-attitude-for-telemedicine-approaches-in-obstetrics-a-case-control-study
#1
Katharina Schramm, Florian Lapert, Juliane Nees, Carlijn Lempersz, S Guid Oei, Markus W Haun, Imad Maatouk, Thomas Bruckner, Christof Sohn, Sarah Schott
PURPOSE: Reduction of maternal morbidity and mortality is a major worldwide objective anchored in the millennium goals of the United Nations. To improve fetal and maternal care, a constant attempt to discover groundbreaking technologies is ongoing. One approach is the enhancement of non-invasive fetal ECG devices. Most importantly, acceptance of new technologies by pregnant women is a prerequisite for successful implementation. METHODS: This questionnaire-based study conducted at the University Hospital Heidelberg, Germany between May and June 2017 evaluates pregnant women's attitudes towards a new device for fetal ECG monitoring and its potential home usage...
September 27, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/30042023/simultaneous-monitoring-of-mouse-respiratory-and-cardiac-rates-through-a-single-precordial-electrode
#2
Motoshige Sato, Nobuyoshi Matsumoto, Asako Noguchi, Toya Okonogi, Takuya Sasaki, Yuji Ikegaya
Normal respiratory and circulatory functions are crucial for survival. However, conventional methods of monitoring respiration, some of which use sensors inserted into the nasal cavity, may interfere with naïve respiratory rates. In this study, we conducted a single-point measurement of electrocardiograms (ECGs) from the pectoral muscles of anesthetized and waking mice and found low-frequency oscillations in the ECG baseline. Using the fast Fourier transform of simultaneously recorded respiratory signals, we demonstrated that the low-frequency oscillations corresponded to respiratory rhythms...
June 2018: Journal of Pharmacological Sciences
https://www.readbyqxmd.com/read/29676832/circulating-mirnas-in-acute-new-onset-atrial-fibrillation-and-their-target-mrna-network
#3
Ananília Medeiros Gomes da Silva, Jéssica Nayara Góes de Araújo, Katiene Macêdo de Oliveira, Ana Eloísa Melo Novaes, Mariana Borges Lopes, Júlio César Vieira de Sousa, Antônio Amorim de Araújo Filho, André Ducati Luchessi, Adriana Augusto de Rezende, Mário Hiroyuki Hirata, Vivian Nogueira Silbiger
BACKGROUND: MicroRNAs (miRNAs) are involved in the pathogenesis of atrial fibrillation (AF), acting on development and progression. Our pilot study investigated the expression of six miRNAs and their miRNA-mRNA interactions in patients with acute new-onset AF, well-controlled AF, and normal sinus rhythm (controls). METHODS AND RESULTS: Plasma of acute new-onset AF patients (n = 5) was collected in the emergency room when patients presented with irregular and fast-atrial fibrillation rhythm...
August 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29552426/physiological-recording-in-the-mri-environment-prime-mri-compatible-hemodynamic-recording-system
#4
John W Kakareka, Anthony Z Faranesh, Randall H Pursley, Adrienne Campbell-Washburn, Daniel A Herzka, Toby Rogers, Josh Kanter, Kanishka Ratnayaka, Robert J Lederman, Thomas J Pohida
Hemodynamic recording during interventional cardiovascular procedures is essential for procedural guidance, monitoring patient status, and collection of diagnostic information. Recent advances have made interventions guided by magnetic resonance imaging (MRI) possible and attractive in certain clinical scenarios. However, in the MRI environment, electromagnetic interference (EMI) can cause severe distortions and artifacts in acquired hemodynamic waveforms. The primary aim of this paper was to develop and validate a system to minimize EMI on electrocardiogram (ECG) and invasive blood pressure (IBP) signals...
2018: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29494497/an-interoperable-system-toward-cardiac-risk-stratification-from-ecg-monitoring
#5
Cristina Soguero-Ruiz, Inmaculada Mora-Jiménez, Javier Ramos-López, Teresa Quintanilla Fernández, Antonio García-García, Daniel Díez-Mazuela, Arcadi García-Alberola, José Luis Rojo-Álvarez
Many indices have been proposed for cardiovascular risk stratification from electrocardiogram signal processing, still with limited use in clinical practice. We created a system integrating the clinical definition of cardiac risk subdomains from ECGs and the use of diverse signal processing techniques. Three subdomains were defined from the joint analysis of the technical and clinical viewpoints. One subdomain was devoted to demographic and clinical data. The other two subdomains were intended to obtain widely defined risk indices from ECG monitoring: a simple-domain (heart rate turbulence (HRT)), and a complex-domain (heart rate variability (HRV))...
March 1, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29443088/simultaneous-video-eeg-ecg-monitoring-to-identify-neurocardiac-dysfunction-in-mouse-models-of-epilepsy
#6
Vikas Mishra, Nicole M Gautier, Edward Glasscock
In epilepsy, seizures can evoke cardiac rhythm disturbances such as heart rate changes, conduction blocks, asystoles, and arrhythmias, which can potentially increase risk of sudden unexpected death in epilepsy (SUDEP). Electroencephalography (EEG) and electrocardiography (ECG) are widely used clinical diagnostic tools to monitor for abnormal brain and cardiac rhythms in patients. Here, a technique to simultaneously record video, EEG, and ECG in mice to measure behavior, brain, and cardiac activities, respectively, is described...
January 29, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29284918/telemedicine-in-cardiology-perspectives-in-bosnia-and-herzegovina
#7
REVIEW
Nabil Naser, Salih Tandir, Edin Begic
Introduction: Aim of article was to present perspectives of telemedicine in the field of cardiology in Bosnia and Herzegovina. Material and methods: Article has descriptive character and present review of literature. Results: Information technology can have the application in the education of students, starting from basic medical sciences up to clinical subjects. Information technologies are used for ECG analysis, 24h ECG Holter monitoring, which detects different rhythm disorders...
December 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29283067/safety-limits-of-antidepressant-use-plus-combinations-focus-on-cardiovascular-function
#8
Florindo Stella, Julia C Loureiro, Marcos V Pais, Paulo R Canineu, Orestes V Forlenza
BACKGROUND: Antidepressants have been widely prescribed for depression, anxiety, sleep disorders, and in the management of behavioural symptoms of adult-old patients. Although generally safe, newer generation antidepressants are not devoid of the risk of inducing clinically relevant adverse events. OBJECTIVES: To investigate the association between newer generation antidepressants and the occurrence of cardiovascular adverse events and electrocardiogram (ECG) abnormalities...
2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29245320/qtc-prolongation-and-torsades-de-pointes-due-to-a-coadministration-of-fluoxetine-and-amiodarone-in-a-patient-with-implantable-cardioverter-defibrillator-case-report-and-review-of-the-literature
#9
REVIEW
Anhua Wei, Jinlan Peng, Zhichun Gu, Juan Li
RATIONALE: Drug-induced prolongation of the corrected QT interval (QTc) may lead to serious and potentially life-threatening ventricular tachyarrhythmia, such as torsades de pointes (Tdp), which is worthy of clinical attention. Here, we report 1 case of Tdp after a coadministration of fluoxetine and amiodarone. PATIENT CONCERNS: A 62-year-old Chinese male who placed with the implanted cardioverter-defibrillator (ICD) appeared the QTc prolongation and Tdp after the concurrent administration of fluoxetine and amiodarone...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29181725/association-between-left-atrial-phasic-conduit-function-and-early-atrial-fibrillation-recurrence-in-patients-undergoing-electrical-cardioversion
#10
Anna Degiovanni, Enrico Boggio, Eleonora Prenna, Chiara Sartori, Federica De Vecchi, Paolo N Marino
BACKGROUND: Diastolic dysfunction promotes atrial fibrillation (AF) inducing left atrial (LA) remodeling, with chamber dilation and fibrosis. Predominance of LA phasic conduit (LAC) function should reflect not only chamber alterations but also underlying left ventricular (LV) filling impairment. Thus, LAC was tested as possible predictor of early AF relapse after electrical cardioversion (EC). METHODS: 96 consecutive patients, who underwent EC for persistent non-valvular AF, were prospectively enrolled...
April 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29114227/non-linear-heart-rate-and-blood-pressure-interaction-in-response-to-lower-body-negative-pressure
#11
Ajay K Verma, Da Xu, Amanmeet Garg, Anita T Cote, Nandu Goswami, Andrew P Blaber, Kouhyar Tavakolian
Early detection of hemorrhage remains an open problem. In this regard, blood pressure has been an ineffective measure of blood loss due to numerous compensatory mechanisms sustaining arterial blood pressure homeostasis. Here, we investigate the feasibility of causality detection in the heart rate and blood pressure interaction, a closed-loop control system, for early detection of hemorrhage. The hemorrhage was simulated via graded lower-body negative pressure (LBNP) from 0 to -40 mmHg. The research hypothesis was that a significant elevation of causal control in the direction of blood pressure to heart rate (i...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29060653/a-robust-automatic-mechanism-for-electrocardiogram-interpretation-in-telehealthcare
#12
Te-Wei Ho, Feipei Lai
Telehealthcare has become increasingly popular in clinical practice as a means of providing ubiquitous healthcare through long-term informative interactions and health monitoring. We have delivered a synchronized telehealthcare program since 2009. We have implemented a web-based clinical decision support system with a knowledge-based electrocardiogram (ECG) recognition mechanism as an augmentation service to assist medical practitioners doing decision making in clinical practice. To evaluate the capability and usage limits of this automatic ECG interpretation, the aim of this study was to validate the stability and robustness of proposed mechanism using stress testing through six simulation scenarios...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059981/towards-precise-tracking-of-electric-mechanical-cardiac-time-intervals-through-joint-ecg-and-bcg-sensing-and-signal-processing
#13
Haihong Zhang, Zimin Wang, Kejun Dong, Soon Huat Ng, Zhiping Lin
Automatic tracking of intra-beat cardiac activities in ballistocardiogram (BCG) is a highly interesting yet technically challenging topic for cardiac monitoring, due to the signal's high susceptibility to various forms of distortions. In this paper, we aim to further investigate the BCG waveform detection from a signal processing and analysis viewpoint. We collect synchronized electrocardiography(ECG) and BCG recordings from four healthy human subjects using an in-house built multi-physiological monitoring device...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28643129/magnetohydrodynamic-voltage-recorder-for-comparing-peripheral-blood-flow
#14
Kevin J Wu, T Stan Gregory, Michael C Lastinger, Jonathan R Murrow, Zion Tsz Ho Tse
Blood flow is a clinical metric for monitoring of cardiovascular diseases but current measurements methods are costly or uncomfortable for patients. It was shown that the interaction of the magnetic field (B 0 ) during MRI and blood flow in the body, through the magnetohydrodynamic (MHD) effect, produce voltages (V MHD ) observable through intra-MRI electrocardiography (ECG), which are correlated with regional blood flow. This study shows the reproducibility of V MHD outside the MRI and its application in a portable flow monitoring device...
October 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28572771/measures-of-heart-rate-variability-in-24-h-ecgs-depend-on-age-but-not-gender-of-healthy-children
#15
Waldemar Bobkowski, Magdalena E Stefaniak, Tomasz Krauze, Katarzyna Gendera, Andrzej Wykretowicz, Jaroslaw Piskorski, Przemyslaw Guzik
Many methods computing heart rate variability (HRV) have been applied in studies in children. Not all of these methods have a comprehensive physiological interpretation, and not all of studies are in agreement with the Task Force Standards on HRV from 1996, and the New Joint Position Statement on the advances of HRV from 2015. The study aim was to analyse HRV in the 24-h ECGs of healthy children by the Poincare plots and Lomb-Scargle periodograms, and to follow proper HRV recommendations. Additionally, we investigated the associations between age, children's sex and measured HRV indices...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28057550/pharmacokinetics-of-lbpt-and-its-primary-metabolites-as-well-as-tolerability-in-the-first-in-human-study
#16
RANDOMIZED CONTROLLED TRIAL
Hongyun Wang, Hongzhong Liu, Ming Liu, Wenjie Wang, Liya Zhu, Haihong Huang, Pei Hu, Ji Jiang
BACKGROUND: LBPT is a novel platelet-activating factor (PAF) receptor antagonist that is developed for the treatment of rheumatoid arthritis. The purpose of this first-in-human study was to evaluate the tolerability and safety of LBPT, to investigate the pharmacokinetics of LBPT and its primary metabolites, as well as to assess the food effect on the pharmacokinetics in healthy Chinese subjects. MATERIALS AND METHODS: LBPT was evaluated in 2 clinical studies. The first study was a double blind, placebo-controlled and ascending dose study...
March 30, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28027554/features-of-coronary-heart-disease-development-in-emergency-workers-of-the-chornobyl-accident-depending-on-the-action-of-radiation-and-non-radiation-risk-factors-and-genotypes-of-single-nucleotide-polymorphism-rs966221-of-phosphodiesterase-4d-gene
#17
D Belyi, G Pleskach, O Nastina, G Sidorenko, N Kursina, O Bazyka, O Kovalev, A Chumak, I Abramenko
OBJECTIVE: This study devoted to specific features of coronary heart disease (CHD) development in emergency work ers (EW) of the accident at the Chernobyl nuclear power plant (ChNPP) based on analysis the interaction between radiation and non radiation risk factors and single nucleotide polymorphism (SNP) rs966221 of phosphodiesterase (PDE) 4D gene. METHODS: It was examined 397 men with CHD, including 274 EW of 1986-1987 and 123 non irradiated persons (con trol group) who were 66±10 and 69±11 years old relatively...
December 2016: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/28009317/-evaluation-of-the-realtionship-of-different-pathogenic-factors-and-arrhythmias-in-patients-with-pulmonary-tuberculosis-and-diabetes
#18
Z Kurbanova, A Bahshaliyev, R Bayramov, J Ismailzada
Definition of the most important factors and their combination, causing the disturbances of heart rhythm in patients with the pulmonary tuberculosis and diabetes, now attracts more and more attention. For this purpose, extensively used the capabilities of multifactorial analysis, which allowed to evaluate the distribution of the pathological factors and their interaction with each other. The objects of the study were complex examination the data of 90 patients with pulmonary tuberculosis and diabetes (insulin-dependent diabetes-27, non-insulin- dependent diabetes-63)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28008519/the-importance-of-hemolysis-in-the-lethal-effects-of-equnatoxin-ii-a-protein-from-the-sea-anemone-actinia-equina-l
#19
Matjaž Bunc, Renata Bregar, Dušan Šuput
Equinatoxin II (EqT II) is one of the three isotoxins isolated from the sea anemone Actinia equina (L.). The cause of death due to i.v. application of Eq T II was attributed to its hemolytic activity and hiperkaliemia, and the direct cardio-respiratory effects of the toxin. The toxin also binds to plasma lipids and forms toxic conglomerates with them. In our study we tried to evaluate the importance of interaction of the toxin with blood components in the toxin lethality. Anaesthetized male Wistar rats were used...
January 2000: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27174779/does-total-antioxidant-capacity-modify-adverse-cardiac-responses-associated-with-ambient-ultrafine-accumulation-mode-and-fine-particles-in-patients-undergoing-cardiac-rehabilitation
#20
Meng Wang, Mark J Utell, Alexandra Schneider, Wojciech Zareba, Mark W Frampton, David Oakes, Philip K Hopke, Jelani Wiltshire, Cathleen Kane, Annette Peters, Susanne Breitner, David Chalupa, David Q Rich
BACKGROUND: Previous studies suggest that pathways reducing oxidative stress may have a protective effect against adverse cardiac responses associated with ambient PM. However, few studies have directly assessed total antioxidant capacity (TAC) as a potential effect modifier of cardiac responses to increased ambient PM. OBJECTIVES: We examined if TAC modifies the association between ambient PM and markers of heart rate variability (HRV), repolarization, systemic inflammation, and systolic blood pressure (SBP) in post-infarction patients...
August 2016: Environmental Research
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