keyword
https://read.qxmd.com/read/32568191/national-dementia-biobank-a-strategy-for-the-diagnosis-and-study-of-neurodegenerative-diseases-in-m%C3%A3-xico
#1
JOURNAL ARTICLE
Aldelmo Emmanuel Reyes-Pablo, B Berenice Campa-Córdoba, Nabil Itzi Luna-Viramontes, Miguel Ángel Ontiveros-Torres, Ignacio Villanueva-Fierro, Marely Bravo-Muñoz, Bárbara Sáenz-Ibarra, Oralia Barbosa, Parménides Guadarrama-Ortíz, Linda Garcés-Ramírez, Fidel de la Cruz, Charles R Harrington, Sandra Martínez-Robles, Erik González-Ballesteros, George Perry, Mar Pacheco-Herrero, José Luna-Muñoz
We recently developed the National Dementia Biobank in México (BioBanco Nacional de Demencias, BND) as a unit for diagnosis, research, and tissue transfer for research purposes. BND is associated with the Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico (UNAM), Mexico. The donation of fluids, brain, and other organs of deceased donors is crucial for understanding the underlying mechanisms of neurodegenerative diseases and for the development of successful treatment...
2020: Journal of Alzheimer's Disease: JAD
https://read.qxmd.com/read/32338488/-pathological-and-clinical-comparison-of-parkinson%C3%A2-s-disease-dementia-and-dementia-with-lewy-bodies
#2
REVIEW
Viktor Bencs, János Bencze, V László Módis, Viktória Simon, János Kálmán, Tibor Hortobágyi
Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) are two major neurodegenerative diseases sharing common clinical, pathophysiological and morphologic features. The pathological hallmark of both diseases is the presence of Lewy-bodies (LB). The main constituent of these inclusions is the pathologically aggregated α-synuclein protein. In DLB, LBs are predominantly located in the cortex, whereas in PDD, the subcortical regions are predominantly affected. Furthermore, in DLB, coexisting Alzheimer's disease (AD), pathology with β-amyloid plaques and neurofibrillary tangles are more common...
May 1, 2020: Orvosi Hetilap
https://read.qxmd.com/read/32186624/-reserva-cognitiva-y-demencias-limitaciones-del-efecto-protector-en-el-envejecimiento-y-el-deterioro-cognitivolimited-protective-effects-of-cognitive-reserve-on-the-progression-of-cognitive-impairment
#3
JOURNAL ARTICLE
David Toloza Ramírez, Diana Martella
Aging constitutes a series of physical, physiological and cognitive changes, affecting independence in the activities of daily living. During this stage, neurodegenerative diseases and cognitive impairment are common. Cognitive Reserve allows to face neuropathological changes and maintain cognitive function in the presence of brain damage. However, there are cases where a high cognitive reserve fails to attenuate and delay the effects of neuropathology, allowing the progression of cognitive damage to advanced stages...
December 2019: Revista Médica de Chile
https://read.qxmd.com/read/31282168/-prevalence-of-sarcopenia-and-characteristics-of-sarcopenic-subjects-in-patients-over-80-years-with-hip-fracture
#4
JOURNAL ARTICLE
Carmen Sánchez-Castellano, Sagrario Martín-Aragón, Nieves Vaquero-Pinto, Paloma Bermejo-Bescós, Ana Merello de Miguel, Alfonso-José Cruz-Jentoft
Aim: to estimate the prevalence of sarcopenia in very old patients admitted to an Orthogeriatric Unit for the treatment of a hip fracture (HF), and to compare characteristics of patients with and without sarcopenia. Methods: one hundred and fifty consecutive patients ≥ 80 years old admitted with HF were included. Sarcopenia was diagnosed with low muscle mass (bioimpedance, using two different cut-off points, Janssen and Masanés) and low grip strength (Jamar's dynamometer). Socio-demographic, nutritional variables (MNA-SF, body mass index [BMI], phase angle), cognitive (Pfeiffer, Reisberg's GDS) and functional variables (Barthel index, FAC) were registered, as well as the number of recent falls and medications on admission...
August 26, 2019: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/30868902/-assessment-of-the-risk-of-undernutrition-in-institutionalized-patients-under-the-degree-of-dependence
#5
JOURNAL ARTICLE
María Ángeles Penacho Lázaro, Alicia Calleja Fernández, Sandra Castro Penacho, Ana María Tierra Rodríguez, Alfonso Vidal Casariego
Background: there is a high number of dependent older adults with risk of malnutrition in the institutionalized geriatric population. Among others, the related factors are weight loss inherent to age, which favors frailty and sarcopenia, low body mass index (BMI) and the worsening of chronic diseases, which entails a deterioration in the quality of life. Objective: to analyze the relationship between dependence and nutritional status in elderly institutionalized people. Method: prospective observational and descriptive study in a sample of elderly institutionalized people...
April 10, 2019: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/29733071/symmetrical-and-bilateral-basal-ganglia-calcification-case-series-and-literature-review
#6
REVIEW
Amado Jiménez-Ruiz, Omar Cárdenas-Sáenz, José Luis Ruiz-Sandoval
Introduction: Symmetric, bilateral basal ganglia calcification is rare finding that sometimes occurs asymptomatically. Its prevalence increases with age, and the most affected site is the globus pallidus. Report of cases: A series of seven cases with clinical and imaging diagnosis of basal ganglia calcification, recorded during the 2012 to 2016 period at the Department of Internal Medicine of the Hospital Civil de Guadalajara "Fray Antonio Alcalde, is presented...
2018: Gaceta Médica de México
https://read.qxmd.com/read/29107401/-map-of-alzheimer-s-disease-and-other-dementias-in-spain-mapea-project
#7
JOURNAL ARTICLE
Pablo Martínez-Lage, Manuel Martín-Carrasco, Enrique Arrieta, Jesús Rodrigo, Francesc Formiga
INTRODUCTION: In the current context of increased life expectancy and progressive aging of the population a very significant increase in the number of people with cognitive impairment and dementia is expected. Consequently, Spain will face an enormous social and health problem in the next decades. The Mapa de la enfermedad de Alzheimer y otras demencias en España project aims to analyse plans, prevention and early diagnosis activities, process of care and resources available across the 17 Spanish regions for the management of cognitive impairment and dementia in order to identify improvement areas, as well as to provide a list of recommendations...
January 2018: Revista Española de Geriatría y Gerontología
https://read.qxmd.com/read/28793095/vulnerability-of-caregivers-of-the-elderly-with-dementia-a-cross-sectional-descriptive-study
#8
JOURNAL ARTICLE
Bruna Silva Leite, Alessandra Conceição Leite Funchal Camacho, Fabiana Lopes Joaquim, Jonas Lírio Gurgel, Thiago Rodrigues Lima, Raquel Santos de Queiroz
OBJECTIVE: to evaluate the sociodemographic and clinical profile of the caregivers and its relation with the overburden from the care of the elderly with dementia. METHOD: a cross-sectional descriptive study; the sample was non-probabilistic, developed with caregivers of elderly people with dementia. The field of investigation was the Health Care Center of the Elderly and their Caregivers (CASIC), in the city of Niterói, Rio de Janeiro, Brazil. Data collection took place from February to June 2016, with the following instruments: a sociodemographic questionnaire and Zarit scale...
July 2017: Revista Brasileira de Enfermagem
https://read.qxmd.com/read/28591300/risk-factors-for-unstable-blood-glucose-level-integrative-review-of-the-risk-factors-related-to-the-nursing-diagnosis
#9
REVIEW
Andressa Magalhães Teixeira, Rosangela Tsukamoto, Camila Takáo Lopes, Rita de Cassia Gengo E Silva
Objective: to identify evidence in the literature on the possible risk factors for the risk of unstable blood glucose diagnosis in individuals with type 2 diabetes mellitus, and to compare them with the risk factors described by NANDA International. Method: an integrative literature review guided by the question: what are the risk factors for unstable blood glucose level in people with type 2 diabetes mellitus? Primary studies were included whose outcomes were variations in glycemic levels, published in English, Portuguese or Spanish, in PubMed or CINAHL between 2010 and 2015...
June 5, 2017: Revista Latino-americana de Enfermagem
https://read.qxmd.com/read/28562815/health-conditions-and-memory-performance-a-study-with-older-adult-women
#10
JOURNAL ARTICLE
Alice Milani Nespollo, Samira Reschetti Marcon, Nathalie Vilma Pollo de Lima, Tatiane Lebre Dias, Mariano Martínez Espinosa
Objective: to verify the correlation between health condition and memory performance of older adult women in the community. Method: Analytical cross-sectional study developed with 28 older adult women living in Cuiabá-MT. They answered the Mini-Mental State Examination (MMSE), and a shortened Geriatric Depression Scale (GDS-15) to screen for dementia and depression symptoms. Memory skills were assessed through Rey Auditory Verbal Learning Test (RAVLT). Results: The mean age was 66...
May 2017: Revista Brasileira de Enfermagem
https://read.qxmd.com/read/28421789/-how-does-coconut-oil-affect-cognitive-performance-in-alzheimer-patients
#11
JOURNAL ARTICLE
José Enrique De la Rubia Ortí, Carmen Sánchez Álvarez, Pablo Selvi Sabater, Alma María Bueno Cayo, Sandra Sancho Castillo, Mariano Julián Rochina, Iván Hu Yang
Introduction: Alzheimer’s disease is one of the most prevalent neurodegenerative dementia in developed world. This fact, coupled with the lack cure, makes new no pharmacological therapeutic strategies such as nutrient management to investigate. In this regard, it stresses the possible influence of coconut oil as alternative energy source capable of stopping the progressively neuronal death that occurs in this disease. Objectives: To assess the cognitive impact of coconut oil in Alzheimer’s patients, and specifically in orientation, language-building, fixing, calculation-concentration and memory areas...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/27780616/perceived-quality-in-a-dementia-unit-patients-caregivers-as-information-providers
#12
JOURNAL ARTICLE
J J López-Picazo, J de Dios Cánovas-García, C Antúnez, J Marín, M M Antequera, L Vivancos, B Martínez, A Legaz, D Navarro, M Leal
INTRODUCTION: Dementia units (DU) provide comprehensive and specialised care to patients with dementia. However, assessment in these units normally focuses on patient management. The aim of this study was to determine satisfaction of the caregivers of patients managed in a DU and how they rated DU care. METHODS: We created a self-administered questionnaire which was completed by 236 caregivers visiting the DU in 2015. The questionnaire included 6 dimensions (accessibility, organisation, professionalism, relationship with staff, information, and facilities); data were analysed using problem rates...
2018: Neurología
https://read.qxmd.com/read/27571865/nutrition-and-cognitive-impairment
#13
REVIEW
Virgilio Hernando-Requejo
Dementia, closely linked to environmental predisposing factors such as diet, is a public health problem of increasing magnitude: currently there are more than 35 million patients with Alzheimer´s disease, and is expected to exceed 135 million by 2050. If we can delay the development of dementia 5 years will reduce its prevalence by 50%. Patients with dementia modify their diet, and it has been reported in them deficits, among others, of folic acid, vitamin B12, B6, C, E, A, D, K, beta carotene and omega 3 fatty acids, that must be resolved with proper diet and with extra contributions if needed in some cases...
July 12, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/27533264/neuropsychiatric-symptoms-of-the-elderly-with-alzheimer-s-disease-and-the-family-caregivers-distress
#14
JOURNAL ARTICLE
Luana Baldin Storti, Débora Teles Quintino, Natália Michelato Silva, Luciana Kusumota, Sueli Marques
OBJECTIVE: to analyze the relationship between the distress of the family caregiver and the presence of neuropsychiatric symptoms in elderly patients with Alzheimer's disease or mixed dementia. METHOD: a descriptive, cross-sectional study conducted in the Geriatric and Dementias Clinic of a general tertiary hospital, with 96 elderly people with Alzheimer's disease or mixed dementia and their family caregivers. Questionnaires to characterize the elderly and caregivers, and the Neuropsychiatric Inventory were used...
August 15, 2016: Revista Latino-americana de Enfermagem
https://read.qxmd.com/read/27462888/pain-assessment-in-elderly-with-dementia-brazilian-validation-of-the-pacslac-scale
#15
JOURNAL ARTICLE
Karol Bezerra Thé, Fernanda Martins Gazoni, Guilherme Liausu Cherpak, Isabel Clasen Lorenzet, Luciana Alves Dos Santos, Edlene Maria Nardes, Fânia Cristina Dos Santos
OBJECTIVE: To validate the Pain Assessment Checklist for Seniors with Limited Ability to Communicate - Portuguese in demented elderly and to analyze its measurement properties. METHODS: We evaluated 50 elderly with dementia, residing in a nursing home and with limited communication ability, when exposed to potentially painful situations. The tool was applied at two different moments. First, two interviewers applied it simultaneously, and the intensity of pain was asked based on the caregiver's opinion...
2016: Einstein
https://read.qxmd.com/read/25946535/-nutritional-approaches-to-modulate-oxidative-stress-that-induce-alzheimer-s-disease-nutritional-approaches-to-prevent-alzheimer-s-disease
#16
REVIEW
Humberto Herman Lara, Eduardo Javier Alanís-Garza, María Fernanda Estrada Puente, Lucía Liliana Mureyko, David Alejandro Alarcón Torres, Liliana Ixtepan Turrent
Alzheimer's disease is the most common cause of dementia in the world; symptoms first appear after age 65 and have a progressive evolution. Expecting an increase on its incidence and knowing there is currently no cure for Alzheimer's disease, it is a necessity to prevent progression. The change in diet due to globalization may explain the growth of the incidence in places such as Japan and Mediterranean countries, which used to have fewer incidences. There is a direct correlation between disease progression and the increased intake of alcohol, saturated fats, and red meat...
March 2015: Gaceta Médica de México
https://read.qxmd.com/read/25076274/-cultural-adaptation-of-the-scale-pain-assessment-in-advanced-dementia-painad-to-brazil
#17
JOURNAL ARTICLE
Gabriela Gallego Valera, Natália Lindemann Carezzato, Francisco Assis Carvalho Vale, Priscilla Hortense
OBJECTIVE: To translate and culturally adapt to Brazil the scale Pain Assessment in Advanced Dementia(PAINAD). METHOD: The cultural adaptation process followed the methodology of a theorical reference, in five steps: translation to Brazilian Portuguese, consensual version of translations, back-translation to the original language, revision by a committee of specialists in the field and a equivalency pre-test. The instrument was assessed and applied by 27 health professionals in the last step...
June 2014: Revista da Escola de Enfermagem da U S P
https://read.qxmd.com/read/24358684/-impact-of-vitamin-d-in-neurological-diseases-and-neurorehabilitation-from-dementia-to-multiple-sclerosis-part-i-the-role-of-vitamin-d-in-the-prevention-and-treatment-of-multiple-sclerosis
#18
REVIEW
Gábor Speer
The world-wide incidence of vitamin D deficiency is high, independently of age. Multiple sclerosis is a chronic disorder, occuring in those who possess or are exposed to a combination of genetic and environmental risk factors. One of the environmental factors associated with the development is vitamin D. Vitamin D is an immunomodulatory agent, its role is verified in many of autoimmune diseases. Vitamin D inhibits IL-6, IL-17 and IL-23 secretions which are crucial in Th1 and Th17 differentiation and also decreases proinflammatorical cytokine production...
September 30, 2013: Ideggyógyászati Szemle
https://read.qxmd.com/read/22633250/-pharmacological-treatment-of-dementia-when-how-and-for-how-long-recommendations-of-the-working-group-on-dementia-of-the-catalan-society-of-geriatrics-and-gerontology
#19
JOURNAL ARTICLE
Daniel Rodríguez, Francesc Formiga, Isabel Fort, María José Robles, Elena Barranco, Dolors Cubí
Dementia in general--and Alzheimer's disease (AD) in particular--are bound to loom large among the most acute healthcare, social, and public health problems of the 21st century. AD shows a degenerative progression that can be slowed down--yet not halted--by today's most widely accepted specific treatments (those based on cholinesterase inhibitors as well as those using memantine). There is enough evidence to consider these treatments advisable for the mild, moderate and severe phases of the illness. However, in the final stage of the disease, a decision has to be made on whether to withdraw such treatment or not...
2012: Revista Española de Geriatría y Gerontología
https://read.qxmd.com/read/22451126/-clinical-and-demographic-characteristics-of-the-cases-of-dementia-diagnosed-in-the-health-district-of-girona-throughout-the-period-2007-2010-data-from-the-girona-dementia-registry-redegi
#20
JOURNAL ARTICLE
L Calvo-Perxas, M T Osuna, J Gich, E Eligio-Hernandez, M Linares, M Vinas, I Casas, O Turro-Garriga, S Lopez-Pousa, J Garre-Olmo
INTRODUCTION: The Girona Dementia Registry (ReDeGi, from Spanish: Registro de Demencias de Girona) is a population-based epidemiological surveillance mechanism that registers the cases of dementia diagnosed by the reference centres in the Girona Health District. AIM: To report on the frequency of the diagnoses and their clinical and sociodemographic characteristics, as well as to compare differences depending on the different subtypes of dementia. PATIENTS AND METHODS: The method used consisted in a consecutive standardised register of the diagnoses involving dementia in specialised procedures in the Girona Health District between 2007 and 2010...
April 1, 2012: Revista de Neurologia
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