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Surgical histopathology

G J Chai, Y D Meng, Y Liu, M Zhao
Summary External auditory canal HIV-associated Kaposi sarcoma is rare. A 47-year-old male patient found a lump locked in the right external auditory canal gradually enlarging during the 4 months. Preoperative examination suggested that the patient had infected with HIV. After surgical removal of the mass, the result of histopathological examination is Kaposi sarcoma. Postoperatively, the patient take tenofovir, lamivudine and efavirenz regularly. After follow-up for 2 years, no local recurrence or metastasis could be found after excision...
December 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Q L Xiong, X F Jiao, L S Wu, X Zhang, Y Q Tian, D H Huang
Summary Two patients both complained of one year history of hoarseness and the clinical manifestations and imageology among 2 patients were lack of specificity. The pathological tissue was successfully eradicated by surgical removal. Histopathology established laryngeal malignant melanoma as the diagnosis. The clinical manifestations and imageology were lack specificity between laryngeal malignant melanoma, laryngeal cancer and other malignant tumor, the diagnosis is difficult, often confirmed by postoperative pathology, the treatment is often by surgery and have a poor prognosis...
December 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Hadrien Stolz, Thierry Rod Fleury, Sana Boudabbous, Didier Hannouche
Cartilaginous tumours are rare and often incidentally discovered on imaging. They can also be responsible for osteoarticular symptoms (pain, joint stiffness, deformity or fracture) and will require a clinical, radiological and a histopathological assessment. Depending on the lesion, the management may consist of observation or a complex surgical procedure that will take place after a multidisciplinary discussion including the radiologist, the pathologist and the orthopaedic surgeon. The discovery of such cartilage tumours often induces a significant dose of anxiety in the affected patients...
December 12, 2018: Revue Médicale Suisse
Hitoshi Kondo, Yumiko Kagawa, Kinji Shirota, Peter F Moore, Masahiko Nagata
A 5-year-old, spayed female French Bulldog presented with multiple papules on the skin of the scapular area. Histopathological examination of punch biopsy samples revealed dense infiltration of small lymphoid cells in the superficial dermis and in areas surrounding hair follicles. Immunohistochemical analysis indicated that these cells were positive for CD3, CD4, and TCRαβ, but negative for CD1c, CD8α, CD8β, CD11c, CD20, CD45RA, CD90, MHC-II, and TCRγδ. In addition, CD45 was highly expressed, and the proliferation fraction was very low...
December 12, 2018: Veterinary Medicine and Science
Meng-Chen Zhang, Xue-Hua Li, Si-Yun Huang, Ren Mao, Zhuang-Nian Fang, Qing-Hua Cao, Zhong-Wei Zhang, Xu Yan, Min-Hu Chen, Zi-Ping Li, Can-Hui Sun, Shi-Ting Feng
OBJECTIVES: Intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) provides information on both perfusion and diffusion and has been used to evaluate Crohn's disease (CD) activity and fibrosis in children; however, there are no reports on its use in adults. We aimed to determine its value for detecting and grading intestinal fibrosis in adults with CD compared with contrast-enhanced imaging and traditional diffusion-weighted imaging using surgical histopathology as a reference standard...
December 13, 2018: European Radiology
Sakthivel Chinnakkulam Kandhasamy, Anubhav Sangwan, Ashok K Sahoo, Gopalakrishnan Gunasekaran, Neelam Sahani, Thangadurai Ramasamy Raju, Subhashini Puducherry Ravichandran
Cecal leiomyomas are rare benign tumors of smooth muscle arising from the colonic muscularis mucosa or muscularis propria. They are usually asymptomatic in nature and, if symptomatic, may present as pain in the abdomen, intestinal obstruction, or bleeding. In some cases, leiomyoma can cause free perforation leading to peritonitis. Contrast-enhanced computed tomography (CECT) and colonoscopy were the diagnostic modalities used for evaluation. It is extremely unusual for a benign lesion of the cecum to present as a ruptured subcutaneous abscess...
October 9, 2018: Curēus
Nizhen Xu, Yanbing Jian, Yaxi Wang, Wen Tian
The aim of the present study was to investigate potential predictive factors of lymph node metastasis (LNM) and distant metastasis (DM) of medullary thyroid cancer (MTC). A total of 61 patients newly diagnosed with MTC at the General Hospital of the Chinese People's Liberation Army between January 2001 and January 2016 were enrolled and divided into two groups according to the results of preoperative examinations and surgical histopathology as follows: Group NM (without metastases), and group M (with metastases)...
December 2018: Molecular and Clinical Oncology
Susumu Matsukuma, Kiyohaya Obara, Yoshitaka Utsumi, Kosuke Miyai, Hiroaki Takeo, Yoshiro Oshika, Koji Sensaki
Cytokeratin 5/6 (CK5/6), p63, and p40 are commonly used as immunohistochemical markers for squamous cell carcinoma (SqCC) of the lung. To elucidate their positivity in primary pulmonary choriocarcinoma (PPC), the present study examined 4 PPCs, including 1 surgically removed PPC and 3 postmortem PPCs. All PPCs consisted of nested cytotrophoblastic tumor cells and occasional syncytiotrophoblastic tumor cells although 1 surgically removed PPC was markedly affected by pre-operative therapy-associated necrosis and 3 postmortem PPCs coexisted with adenocarcinoma...
December 2018: Oncology Letters
Nitasha Gandhi, Harit Talwar, Sumir Gandhi, Vijay Alageshan, George Abraham, Surbhi Mehdiratta
Squamous cell carcinoma (SCC) of the oral cavity is relatively common in the Indian subcontinent with surgical resection and adjuvant radiotherapy/chemotherapy being the treatment modality of choice. Prosthetic rehabilitation with an obturator following resection is more economical and yields satisfactory results. Better patient acceptance and comfort necessitates hollowing the prosthesis to a great extent. This novel method modifies the existing lost-wax technique in fabricating a definitive hollow maxillary obturator...
July 2018: National Journal of Maxillofacial Surgery
Kara Ozlem, Yakan Birkan, Kara Mustafa, Kaymak Emin
OBJECTIVE: It is aimed to evaluate the protective effect of bilberry on I/R injury in rat ovary. MATERIALS AND METHODS: A total 48 female Wistar-Albino rats were utilized to form five groups: Group 1 (control group) (n = 8), neither drug was given and nor procedure was performed. Group 2 (bilberry control group) (n = 10), single dose 200 mg/kg bilberry was administered by gavage and no procedure was performed. Group 3 (I/R group) (n = 10), no drug was given, 1-h ischemia and 2-h reperfusion was performed...
December 2018: Taiwanese Journal of Obstetrics & Gynecology
Sheyda Jouhari, Afsaneh Mohammadzadeh, Haleh Soltanghoraee, Zohreh Mohammadi, Shaheen Khazali, Ebrahim Mirzadegan, Niknam Lakpour, Farnaz Fatemi, Simin Zafardoust, Arash Mohazzab, Mohammad Mehdi Naderi
OBJECTIVE: Silymarin as an herbal drug has potent antioxidant effects that could make it a good choice for endometriosis therapy. The aim of the current study was to determine the effects of silymarin as an herbal drug on induced endometrial lesion in rat model of endometriosis. MATERIALS AND METHODS: A total of 32 mature, female Sprague-Dawley rats were allocated into 4 experimental groups. The duration of study was about 6 months. Endometriosis implants were surgically prepared and autografted into 32 rats...
December 2018: Taiwanese Journal of Obstetrics & Gynecology
Wei Jiang, Lijin Zhang, Bin Wu, Zhenlei Zha, Hu Zhao, Yuan Jun, Yuefang Jiang
OBJECTIVE: Numerous studies have shown that lymphovascular invasion (LVI) is linked to biochemical recurrence (BCR) in prostate cancer (PCa) patients following radical prostatectomy (RP). However, the actual clinicopathological impacts of LVI remain unclear. Thus, we performed a meta-analysis to evaluate the pathologic and prognostic impacts of LVI in PCa patients. METHODS: Following the guidance of the PRISMA statement, relevant studies were collected systematically from the PubMed, EMBASE, and Web of Science databases to identify relevant studies published before June 2018...
December 2018: Medicine (Baltimore)
Maria Lucia Caruso, Federica Di Pinto, Antonia Ignazzi, Sergio Coletta, Anna Maria Valentini, Elisabetta Cavalcanti, Francesco De Michele
RATIONALE: Inflammatory bowel disease (IBD) patients manifest symptoms of disturbed gut function, such as neural sensory-motor changes. Programmed cell death-ligand 1 (PD-L1), normally present in neural tissue, exists in close apposition to the mucosal immune system and intestinal epithelium, and a bi-directional communication is known to occur at these interfaces. Somatostatin has been shown to suppress the inflammatory reaction, and has been used in several clinical trials to treat inflammatory disorders, such rheumatoid arthritis...
December 2018: Medicine (Baltimore)
Tiantian Han, Ying Jin, Yan Li, Yalan Bi, Lingya Pan
In the recent 20 years, primary vaginal adenosis is extremely rare and the data of clinical presentations, management, and outcome have not been studied systematically.In this retrospective study, women with vaginal adenosis between January 1997 and June 2017 were identified from the hospital's medical records. Data on patient age, history, symptoms, mass location, size, diagnosis, complications, treatment, and recurrence were analyzed by SPSS 20.0.Twenty women were histopathologically diagnosed as having vaginal adenosis (mean age, 37...
December 2018: Medicine (Baltimore)
Kohei Morita, Hisashi Oshiro, Kumiko Mito, Makiko Naka Mieno, Mio Tamba-Sakaguchi, Toshiro Niki, Atsushi Miki, Masaru Koizumi, Yasunaru Sakuma, Toshihide Komatsubara, Naohiro Sata, Noriyoshi Fukushima
Little is known concerning the prognostic significance of the degree of lymphatic vessel invasion in pancreatic head cancer. To address this gap in knowledge, we retrospectively examined 60 patients with locally advanced, surgically resectable pancreatic head cancer who underwent pancreaticoduodenectomy and lymph node (LN) dissection.All cases were histopathologically diagnosed as ductal adenocarcinoma, stage II (25 pT3N0 cases, 35 pT3N1 cases). The following variables were investigated: age; sex; neoadjuvant therapy; adjuvant therapy; tumor size; tumor grade; invasion into the serosa, retropancreatic tissue, duodenum, bile duct, portal venous system and perineural area; cut margins; LN metastasis; and the number of invaded lymphatic vessels (LVI-score)...
December 2018: Medicine (Baltimore)
Krzysztof Kaliszewski, Dorota Diakowska, Marcin Ziętek, Bartłomiej Knychalski, Michał Aporowicz, Krzysztof Sutkowski, Beata Wojtczak
A thyroid nodule discovered during imaging study performed due to unrelated thyroid disease is known as a thyroid incidentaloma, while positron emission tomography (PET) associated incidental neoplasm of thyroid is known as a "PAIN" phenomenon.To evaluate which patients with "PAIN" phenomenon should undergo surgery in regards to cytology results.Retrospective review of 4716 patients consecutively admitted and surgically treated in tertiary surgical center. 49 (1.04%) patients with "PAIN" phenomenon were identified...
December 2018: Medicine (Baltimore)
Takahiro Kirisawa, Ko Kobayashi, Seisuke Nofuji, Fumimasa Fukuta, Kohei Hashimoto, Toshiaki Tanaka, Tadashi Hasegawa, Naoya Masumori
A 74-year-old man visited our clinic for treatment of a retroperitoneal tumor that had enlarged gradually. We performed surgical resection of the tumor because we suspected retroperitoneal liposarcoma radiographically. The histopathological diagnosis was an atypical spindle cell lipomatous tumor. No signs of recurrence or metastasis have been observed for one year after the operation.
November 2018: Hinyokika Kiyo. Acta Urologica Japonica
Abdulsamet Tanık, Arzum Güler Doğru, Veysi Akpolat, Filiz Acun Kaya, Ebru Sarıbaş, Mehmet Gül, Sevgi İrtegün Kandemir, Engin Deveci
Background/aim: In this experimental study, we aimed to evaluate the late period effects of the combination of Ankaferd Blood Stopper (ABS), which has bone wound healing effects, and β-tricalcium phosphate (TCP) on the regeneration of bone tissue through histopathological, immunohistochemical, and radiological (dual energy X-ray absorptiometry - DEXA) methods in nondiabetic rats. Materials and methods: Sixty-four Wistar albino male rats were used. In the calvaria of the rats, a bone defect 7...
December 12, 2018: Turkish Journal of Medical Sciences
A Furdová, P Babál, D Kobzová
INTRODUCTION: Orbital meningioma treatment has achieved significant success over the last period. Primary optic nerve sheath meningiomas by the clinically progressive finding, but still persistent sufficient visual acuity, can be treated by fractionated stereotactic radiotherapy. Surgery is indicated for secondary meningiomas of the orbit. Surgical treatment is indicated due to intracranial tumor propagation of meningioma from the chiasm towards the orbit. MATERIAL AND METHODS: In the period 2014 - 2016 we monitored in dispensary 15 patients with meningioma of the orbit, who were checked at least in yearly intervals and underwent magnetic resonance examination of the orbit and brain...
2018: Ceská a Slovenská Oftalmologie
Nina Meyerhoff, Michael Fehr, Jasmin Neßler, Alexandra Friederike Schütter, Peter Dziallas, Viktor Molnár, Carsten Ludwig, Sarah Zabke, Annika Lehmbecker, Andrea Tipold
Magnetic resonance imaging revealed spinal cord compression due to intervertebral disc herniation of Hansen type I and II in the thoracolumbar vertebral column in two middle-aged coatis ( Nasua nasua ) with chronic progressive paraparesis. Surgical treatment included hemilaminectomy and partial corpectomy in one and dorsal laminectomy in the other coati. Both coatis recovered well after surgery. One showed unremarkable gait 6 and 15 months post surgery, while the other one suffered from recurrence of paraparesis leading to euthanasia because of deterioration of neurological signs 20 months after the first surgery...
October 2018: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
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