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Surgical histopathology

Mahdi Eskandarlou, Alireza Nemati, Mohammad Ali Seif-Rabiei
PURPOSE: We aimed to introduce a new surgical method for open appendectomy including a right groin incision with adipocutaneous flap and to compare its feasibility, safety, and cosmetic outcomes with classic McBurney's incision. METHODS: Patients with the diagnosis of acute appendicitis who were candidates for appendectomy surgery at General Surgery Department, Besat Hospital, Hamadan University of Medical Sciences, Iran, in 2016 and 2017, were enrolled in a randomized controlled clinical study...
October 20, 2018: Langenbeck's Archives of Surgery
Junko Mukohyama, Yasuo Sumi, Kiyonori Kanemitsu, Hiroshi Hasegawa, Masashi Yamamoto, Shingo Kanaji, Yoshiko Matsuda, Kimihiro Yamashita, Takeru Matsuda, Taro Oshikiri, Tetsu Nakamura, Satoshi Suzuki, Yoshihiro Kakeji
INTRODUCTION: Primary appendiceal cancer with fistula formation is extremely rare. We report a case of a patient with appendiceal cancer invading the ileum who underwent successful laparoscopic ileocecal resection. PRESENTATION OF CASE: A 76-year-old man who presented with fever and abdominal pain was diagnosed with acute appendicitis and received antibiotics at a local hospital. After a few days, he was referred to our hospital because of an abnormality found in the colonoscopy, which was an oozing ulcer in the terminal ileum...
October 8, 2018: International Journal of Surgery Case Reports
Susan G Brouwer de Koning, Elisabeth J M Baltussen, M Baris Karakullukcu, Behdad Dashtbozorg, Laura A Smit, Richard Dirven, Benno H W Hendriks, Henricus J C M Sterenborg, Theo J M Ruers
This ex-vivo study evaluates the feasibility of diffuse reflectance spectroscopy (DRS) for discriminating tumor from healthy tissue, with the aim to develop a technology that can assess resection margins for the presence of tumor cells during oral cavity cancer surgery. Diffuse reflectance spectra were acquired on fresh surgical specimens from 28 patients with oral cavity squamous cell carcinoma. The spectra (400 to 1600 nm) were detected after illuminating tissue with a source fiber at 0.3-, 0.7-, 1.0-, and 2...
October 2018: Journal of Biomedical Optics
Suyi Ooi, Matthew Gutman, Chris Xenos, Ronil Chandra, Catriona McLean
Intracranial epithelioid haemangioendothelioma (EHE) is a rare intermediate grade vascular tumour with heterogeneous clinical and histopathological behaviour. We present the surgical considerations of an exceptionally large skull-based EHE in an 11-year old female who presented to our institution with headaches and a protuberance over the left parietal area. Magnetic resonance imaging (MRI) demonstrated a left sided 10.5 × 6.6 × 11.1 cm extra-axial tumour arising from the parieto-temporaloccipital region which was continuous with the calvarium...
October 19, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Kyeong A So, In Ho Lee, Tae Jin Kim, Ki Heon Lee
PURPOSE: To evaluate the risk factors associated with persistent high-risk human papillomavirus (HR HPV) infections in patients undergoing cervical excision for treatment of high-grade squamous intraepithelial lesion (HSIL). METHODS: A retrospective cohort study included 160 patients who underwent cervical excision for treatment of HSIL between January 2014 and December 2014. The clinical characteristics, cervical cytology, and HPV test results were reviewed. Persistent HR HPV infections were identified within 6 months after treatment...
October 19, 2018: Archives of Gynecology and Obstetrics
Clara Q Wu, Lawrence Y Woo, Kurt C Giede, John Thiel, Erwin Karreman, Darrien D Rattray
OBJECTIVE: The risk of unexpected uterine leiomyosarcoma (LMS) following surgery for presumed benign leiomyoma is quoted to be between 1 in 498 and 1 in 5000. The objectives of the present study were to determine the prevalence of uterine LMS in a specific patient population and the rate of diagnosis of occult uterine LMS and to evaluate the risk of unintended morcellation of LMS in Saskatchewan. METHODS: This study was a Canadian Task Force Classification II-2 multicentre retrospective cohort study in academic-affiliated tertiary care centres...
October 16, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
M Martano, S Iussich, E Morello, P Buracco
Canine oral fibrosarcoma (oFSA) is a malignant, infiltrating, mesenchymal tumour affecting the oral cavity primarily of medium to large middle aged dogs. The diagnosis often is made late in the course of the disease, due to the frequent caudal location of the tumour, and histopathology is not always sufficient to discriminate undifferentiated oFSA from other poorly differentiated malignant mesenchymal tumours occurring at the same site, especially in small biopsy samples. The literature exclusively relating to oFSA is limited and outcome data following treatment are difficult to compare...
November 2018: Veterinary Journal
Jian Wang, Wei Cheng, Shaoji Zhang, Yousheng Li, Jieshou Li
OBJECTIVES: Intestinal tuberculosis (ITB) remains prevalent and a big health hazard in China. The aim of this study was to retrospectively analyze its clinico-pathological features. METHODS: Retrospective study of 85 consecutive ITB patients in two tertiary hospitals in East China. Relevant clinical, laboratory examination, radiological, endoscopic and histopathological features of ITB were recorded. RESULTS: The mean age was 37.3±16.0 years; 56 patients (65...
October 18, 2018: Tropical Medicine & International Health: TM & IH
Noeul Kang, Yeonseok Choi, Yunjoo Im, Junsu Choe, Jhingook Kim, Joungho Han, Tae Jeong Kim, Hojoong Kim
Thoracolithiasis is a rare benign condition with mobile free bodies in the pleural cavity. It is asymptomatic and mostly found incidentally. Up to our knowledge there is no report of symptomatic numerous thoracolithiasis. We report a very rare case of thoracolithiasis in a 36-year-old female with chest discomfort. Images from computed tomography presented a chain of small non-enhancing nodules in the left hemi-diaphragmatic pleura. Exploratory thoracoscopy was performed and twenty-five mobile pearl like thoracolithiasis were discovered...
2018: Respiratory Medicine Case Reports
Brad A Hartl, Htet S W Ma, Shamira Sridharan, Katherine S Hansen, Michael S Kent, Fredric Gorin, Ruben C Fragoso, Laura Marcu
Current clinical imaging modalities do not reliably identify brain tissue regions with necrosis following radiotherapy. This creates challenges for stereotaxic biopsies and surgical-decision making. Time-resolved fluorescence spectroscopy (TRFS) provides a means to rapidly identify necrotic tissue by its distinct autofluorescence signature resulting from tissue breakdown and altered metabolic profiles in regions with radiation damage. Studies conducted in a live animal model of radiation necrosis demonstrated that necrotic tissue is characterized by respective increases of 27% and 108% in average lifetime and redox ratio, when compared with healthy tissue...
August 1, 2018: Biomedical Optics Express
Francesco Quaglino, Valentina Marchese, Riccardo Lemini, Alessandro Piovesan, Enrico Mazza, Tiziana Viora, Stefano Taraglio
INTRODUCTION: Parathyroid carcinoma (PC) is a slow-growing and very rare malignancy, representing less than 0.005% of all cancers. The rarity of PC makes it hard to create large-scale published series of patients affected by this condition. MATERIALS AND METHODS: We present four cases of PC treated in our Institution and analyze the most salient aspects of this disease highlighted in recent international literature. DISCUSSION AND COMMENTS: In our experience, in 3/4 cases, the clinical presentation of PC was not different compared to adenoma; therefore, the diagnosis was a post-operative histopathological surprise...
2018: Annali Italiani di Chirurgia
Francesco Quaglino, Valentina Marchese, Riccardo Lemini, Alessandro Piovesan, Enrico Mazza, Tiziana Viora, Stefano Taraglio
INTRODUCTION: Parathyroid carcinoma (PC) is a slow-growing and very rare malignancy, representing less than 0.005% of all cancers. The rarity of PC makes it hard to create large-scale published series of patients affected by this condition. MATERIALS AND METHODS: We present four cases of PC treated in our Institution and analyze the most salient aspects of this disease highlighted in recent international literature. DISCUSSION AND COMMENTS: In our experience, in 3/4 cases, the clinical presentation of PC was not different compared to adenoma; therefore, the diagnosis was a post-operative histopathological surprise...
June 11, 2018: Annali Italiani di Chirurgia
Saleh Baeesa, Peter Jarzem, Mohammed Mansi, Rakan Bokhari, Mahdi Bassi
OBJECTIVE: Spontaneous spinal epidural hematomas (SSEH) are a rare and morbid entity whose prognosis is affected by delayed diagnosis and surgical intervention. Correlation with the time of intervention and neurological recovery is not clearly described in the literature. We present a retrospective study of SSEH, to determine the correlation between the timing of surgical intervention and changes in the spinal cord signal on MRI with the neurological outcome. METHODS: The records of 14 patients who underwent surgical decompression of SSEH over 10-year duration were reviewed...
October 15, 2018: World Neurosurgery
Danielle Leal Vieira, André Ferreira Leite, Paulo Tadeu de Souza Figueiredo, Leonora Maciel Vianna, Carla Ruffeil Moreira-Mesquita, Nilce Santos de Melo
OBJECTIVE: To describe a clinical case of successful conservative management of Localized Juvenile Spongiotic Gingivitis Hyperplasia (LJSGH) using photodynamic therapy (PDT) and reviews the current literature on this pathology. BACKGROUND DATA: LJSGH is a recently described rare disease with controversial treatment results. As of today, 13 publications report surgical treatment approaches. The use of CO2 laser and cryotherapy was reported only in one study. The use of PDT was not previously reported...
October 18, 2018: Photomedicine and Laser Surgery
Maighan A Seagrove-Guffey, Haris Hatic, Haoran Peng, Kimberly C Bates, A Ola Odugbesan
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) was created to establish a standard terminology regarding thyroid nodules that can be shared between endocrinologists, pathologists, radiologists, and surgeons. Since its inception and use in 2009, multiple large hospitals and academic institutions have performed retrospective studies to compare their classification rates, specifically those of atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS), with the recommended rates created by the National Cancer Institute...
October 18, 2018: Cancer Cytopathology
Kun Wang, Feidan Yu, Keng Chen, Huanjiang Niu, Yirong Wang, Shuxu Yang, Xiujun Cai
RATIONALE: Osteoblastoma is an uncommon primary bone tumor that involves any part of the skeleton. But its occurrence in the skull is extremely rare. PATIENTS CONCERNS: A 30-year-old female was admitted to our hospital, because of the mass in the right frontal region with the history of headache for 3 years without nausea or vomiting. DIAGNOSIS: Initial differential diagnoses included hemangiopericytoma, atypical intraosseous meningioma, calvarial osteosarcoma, fibrous dysplasia, and histiocytosis, based on the results of enhanced CT and MRI...
October 2018: Medicine (Baltimore)
Jacek Szczygielski, Cosmin Glameanu, Andreas Müller, Markus Klotz, Christoph Sippl, Vanessa Hubertus, Karl-Herbert Schäfer, Angelika E Mautes, Karsten Schwerdtfeger, Joachim Oertel
Both hypothermia and decompressive craniectomy have been considered as a treatment for traumatic brain injury. In previous experiments we established a murine model of decompressive craniectomy and we presented attenuated edema formation due to focal brain cooling. Since edema development is regulated via function of water channel proteins, our hypothesis was that the effects of decompressive craniectomy and of hypothermia are associated with a change in aquaporin-4 (AQP4) concentration. Male CD-1 mice were assigned into following groups ( n = 5): sham, decompressive craniectomy, trauma, trauma followed by decompressive craniectomy and trauma + decompressive craniectomy followed by focal hypothermia...
2018: Frontiers in Neurology
Daniel Paramythiotis, Petros Bangeas, Anestis Karakatsanis, Alexandros Iliadis, Georgia Karayannopoulou, Antonios Michalopoulos
BACKGROUND: A mesenteric chylous cyst is defined as a cyst occurring in the mesentery of the gastrointestinal tract anywhere from the duodenum to the rectum and is diagnosed most often during the fifth decade of life. CASE PRESENTATION: In our case report, we describe a case of 38-year-old Greek woman who presented at our Emergency Department complaining of abdominal pain without any other symptoms. Her medical and family histories were clear and she had never had any abdominal interventions...
October 17, 2018: Journal of Medical Case Reports
Eduardo de Faria Castro Fleury, Gabriel Salum D'Alessandro, Sheila Cristina Lordelo Wludarski
Currently, attention has been given to complications related to breast implants, especially due to the presence of anaplastic large cell lymphoma (ALCL) related to silicone implants. Many manuscripts attempt to associate silicone presence with clinical complaints reported by patients, while others try to demonstrate the mechanisms of silicone bleeding by permeability loss of breast implant surfaces. There also are reports of foreign body type reactions from implant fibrous capsule to silicone corpuscles. However, there seems to be no study that correlates the clinical, radiological, and histological correlations of these lesions...
2018: Journal of Immunology Research
Shingo Matsuda, Yosuke Kajihara, Masaru Abiko, Takafumi Mitsuhara, Masaaki Takeda, Vega Karlowee, Satoshi Yamaguchi, Vishwa Jeet Amatya, Kaoru Kurisu
Concurrent multiple tumors developing in the spinal cord are rare, except for in genetic disorders, such as neurofibromatosis and von Hippel-Lindau disease. Furthermore, concurrent tumors arising in the same spinal level with discrete histopathology are much rarer. We report two such cases. Case 1: A 53-year-old man presented with intracranial hemorrhage that manifested as disturbed consciousness and right hemiparesis. Magnetic resonance (MR) angiography demonstrated severe stenosis of the terminal portion of the bilateral internal carotid arteries, implying Moyamoya disease...
October 2018: NMC Case Report Journal
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