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Shan Wang

Yanju Yang, Haipeng Zhang, Yuhua Shan, Juanjuan Wang, Xiaoqing Qian, Tianzhu Meng, Jinbo Zhang, Zucong Cai
Denitrification is one of the most important N loss pathways in paddy soil. The nitrification rate is a key natural feature for controlling denitrification N loss in paddy soil. However, the relationship between nitrification and denitrification under different conditions in paddy soil remains unknown. By using 15 N tracing, we investigated the response of denitrification loss to soil moisture and glucose addition in six paddy soils, whose net nitrification rates ranged from 0.36 mg N kg-1  day-1 to 5...
October 9, 2018: Science of the Total Environment
Yu-Shan Sandy Huang, Rebecca L Greenbaum, Julena M Bonner, Cynthia S Wang
We utilize the social intuitionist approach to moral judgment and moral disengagement theory to understand why and when employees sabotage customers. We contend that when customers mistreat employees (i.e., customer mistreatment), employees experience intuitive emotional reactions in the form of hostility, which automatically activates devaluation of targets, a specific facet of moral disengagement. In turn, employees become unencumbered by moral self-regulation and sabotage customers who mistreat them (i.e...
October 15, 2018: Journal of Applied Psychology
Yun-Wei Pang, Xiao-Long Jiang, Ya-Chun Wang, Yang-Yang Wang, Hai-Sheng Hao, Shan-Jiang Zhao, Wei-Hua Du, Xue-Ming Zhao, Lin Wang, Hua-Bin Zhu
Paraquat (PQ), a broad-spectrum agricultural pesticide, causes cellular toxicity by increasing oxidative stress levels in various biological systems, including the reproductive system. PQ exposure causes embryotoxicity and reduces the developmental abilities of embryos. However, there is little information regarding the toxic effects of PQ on oocyte maturation. In this study, we studied the toxic effects of PQ exposure and the effects of melatonin on PQ-induced damage in bovine oocytes. PQ exposure disrupted nuclear and cytoplasmic maturation, which was manifested as decreased cumulus cell expansion, reduced first polar body extrusion, and abnormal distribution patterns of cortical granules and mitochondria...
October 15, 2018: Journal of Pineal Research
Yiyan Wang, Lubin Xie, Erpo Tian, Xiaoheng Li, Zina Wen, Linchao Li, Lanlan Chen, Ying Zhong, Ren-Shan Ge
Oncostatin M (OSM) is a pleiotropic cytokine within the interleukin six family of cytokines, which regulate cell growth and differentiation in a wide variety of biological systems. However, its action and underlying mechanisms on stem Leydig cell development are unclear. The objective of the present study was to investigate whether OSM affects the proliferation and differentiation of rat stem Leydig cells. We used a Leydig cell regeneration model in rat testis and a unique seminiferous tubule culture system after ethane dimethane sulfonate (EDS) treatment to assess the ability of OSM in the regulation of proliferation and differentiation of rat stem Leydig cells...
October 15, 2018: Journal of Cellular and Molecular Medicine
Jian Zhou, Hui-Chuan Sun, Zheng Wang, Wen-Ming Cong, Jian-Hua Wang, Meng-Su Zeng, Jia-Mei Yang, Ping Bie, Lian-Xin Liu, Tian-Fu Wen, Guo-Hong Han, Mao-Qiang Wang, Rui-Bao Liu, Li-Gong Lu, Zheng-Gang Ren, Min-Shan Chen, Zhao-Chong Zeng, Ping Liang, Chang-Hong Liang, Min Chen, Fu-Hua Yan, Wen-Ping Wang, Yuan Ji, Wen-Wu Cheng, Chao-Liu Dai, Wei-Dong Jia, Ya-Ming Li, Ye-Xiong Li, Jun Liang, Tian-Shu Liu, Guo-Yue Lv, Yi-Lei Mao, Wei-Xin Ren, Hong-Cheng Shi, Wen-Tao Wang, Xiao-Ying Wang, Bao-Cai Xing, Jian-Ming Xu, Jian-Yong Yang, Ye-Fa Yang, Sheng-Long Ye, Zheng-Yu Yin, Bo-Heng Zhang, Shui-Jun Zhang, Wei-Ping Zhou, Ji-Ye Zhu, Rong Liu, Ying-Hong Shi, Yong-Sheng Xiao, Zhi Dai, Gao-Jun Teng, Jian-Qiang Cai, Wei-Lin Wang, Jia-Hong Dong, Qiang Li, Feng Shen, Shu-Kui Qin, Jia Fan
Background: Hepatocellular carcinoma (HCC) (about 85-90% of primary liver cancer) is particularly prevalent in China because of the high prevalence of chronic hepatitis B infection. HCC is the fourth most common malignancy and the third leading cause of tumor-related deaths in China. It poses a significant threat to the life and health of Chinese people. Summary: This guideline presents official recommendations of the National Health and Family Planning Commission of the People's Republic of China on the surveillance, diagnosis, staging, and treatment of HCC occurring in China...
September 2018: Liver Cancer
Shan Jiang, Ting Lin, Qingji Xie, Lijing Wang
The RAD51 (DNA repair protein RAD51) recombinases are essential for homologous recombination, DNA repair, and genome stability. Overexpression of RAD51 proteins has been observed in many cancer cells, such as thyroid carcinoma, breast cancer, pancreatic cancer, and others. In Metazoa, there are multiple members of RAD51 (RAD51, RAD51B, RAD51C, RAD51D, DMC1) (DNA meiotic recombinase 1), XRCC2 (X-ray repair cross-complementing 2), and XRCC3. In this study, we used a protein sequence similarity network (SSN) to analyze the evolutionary relationship within this protein family...
2018: Frontiers in Genetics
Ruoyu Guo, Yantao Liang, Yu Xin, Long Wang, Shanli Mou, Chunjie Cao, Ruize Xie, Chuanlun Zhang, Jiwei Tian, Yongyu Zhang
As photoautotrophs, phytoplankton are generally present in the euphotic zone of the ocean, however, recently healthy phytoplankton cells were found to be also ubiquitous in the dark deep sea, i.e., at water depths between 2000 and 4000 m. The distributions of phytoplankton communities in much deeper waters, such as the hadal zone, are unclear. In this study, the vertical distribution of the pico- and nano-phytoplankton (PN) communities from the surface to 8320 m, including the epipelagic, mesopelagic, bathypelagic, and hadal zones, were investigated via both 18S and p23S rRNA gene analysis in the Challenger Deep of the Mariana Trench...
2018: Frontiers in Microbiology
Yu-Jun Tan, Yu-Shan Ren, Lei Gao, Lan-Fang Li, Li-Juan Cui, Bin Li, Xin Li, Jian Yang, Ming-Zhi Wang, Yuan-Yuan Lv, Xiao-Li Xu, Jing-Chun Yao, Zhong Liu, Gui-Min Zhang, Jie Li
Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities. In the present study, the sub-chronic toxicity profile of Arctigenin following 28 days of consecutive exposure was investigated in rats. The results showed that during the drug exposure period, Arctigenin -12 mg/kg administration resulted in focal necrosis and lymphocytes infiltration of heart ventricular septal muscle cells...
2018: Frontiers in Pharmacology
Lu Fan, Ye Fan, Li Liu, Weiwei Tao, Xin Shan, Yu Dong, Lin Li, Sen Zhang, Hanqing Wang
Chelerythrine (CH), is a kind of benzo[c] phenanthridine alkaloid isolated from plants such as Chelidonium, with pharmacological activities as antitumor, antibiosis and anti-inflammation. However, few studies have demonstrated whether CH could protect against lipopolysaccharide (LPS)-induced acute lung injury (ALI), and the underlying mechanism is also uncertain. The purpose of the present study was to investigate the anti-inflammatory effects of CH on LPS-induced ALI in mice and in RAW264.7 cells. In this study, we demonstrated that treatment with CH significantly ameliorated LPS-induced pathological changes in the lung...
2018: Frontiers in Pharmacology
Ziye Xu, Wenjing You, Fengqin Wang, Yizhen Wang, Tizhong Shan
Adipose tissues, function as energy metabolism and endocrine organ, are closely associated with metabolic diseases such as obesity, insulin resistance and diabetes. Liver kinase B1 (Lkb1) and mechanistic target of rapamycin (mTOR) play crucial roles in regulating energy metabolism and cell growth in adipose tissue. Our recent study generated an adipocyte-specific Lkb1 and mTOR double knockout (DKO) mouse model and found that DKO of Lkb1 and mTOR caused reduction of brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) mass but increase of liver mass...
October 14, 2018: Adipocyte
Jin-Hu Wang, Min-Ju Li, Da-Xing Tang, Shan Xu, Jun-Qing Mao, Jia-Bin Cai, Min He, Qiang Shu, Can Lai
BACKGROUND: Clear cell sarcoma of the kidney (CCSK) is a rare and aggressive malignant renal tumor. We describe our experience with neoadjuvant transcatheter arterial chemoembolization (TACE) and systematic chemotherapy for the treatment of advanced CCSK in children. METHODS: Between January 2010 and December 2016, seven patients (3 boys and 4 girls; median 2.2 years) with advanced CCSK received preoperative TACE of renal artery and systemic chemotherapy. The chemoembolic emulsion for TACE consisted of cisplatin, pirarubicin, vindesine, and iodized oil...
October 2, 2018: Journal of Pediatric Surgery
Cong Shan, Lianxu Wang, Zhongxu Li, Xin Zhong, Yaheng Hou, Long Zhang, Fengwei Shi
Biomass aerogel is a promising catalyst and has attracted extensive attention. However, most of the biomass aerogels are fragile, which limits their practical application. Herein, we significantly enhance the mechanical property of biomass aerogel catalysts by 30 times through incorporating graphene oxide into polyacrylamide and Cu-cross-linked alginate formed supper-strong double network aerogels. In addition to enhance the mechanical property, the graphene oxide also significantly increases the catalytic activity...
January 1, 2019: Carbohydrate Polymers
Shuo Wang, Li C Yan, Shan S Zheng, Tian T Li, Ling Y Fan, Tao Huang, Chao Li, Yuan H Zhao
Although mode of action (MOA) plays a key role in the understanding of the toxic mechanism of chemicals, the MOAs of class-based compounds to tadpoles have not been investigated. To explore the MOAs, acute toxicity (expressed as log 1/LC50 ) to Rana chensinensis tadpoles were determined and molecular descriptors were calculated. Quantitative structure-activity relationship (QSAR) showed that toxicity to tadpoles is closely related to the chemical octanol/water partition coefficient (log KOW ), energy of the lowest unoccupied molecular orbital (ELUMO ), and number of hydrogen bond donors and acceptors (NHDA ), representing the bio-uptake potential in tadpoles, the electrophilicity and hydrogen bonding capacity with target site(s), respectively...
October 11, 2018: Ecotoxicology and Environmental Safety
Xin-Ming Gao, Dan-Li Mu, Cong-Cong Hou, Jun-Quan Zhu, Shan Jin, Chun-Lin Wang
Kinesin-14 KIFC1 plays an important role in vesicular transport, microtubule organization, and spermiogenesis. In this study, we first investigated the microtubule distribution and expression pattern of KIFC1 during spermiogenesis of P. esculenta. Microtubules are abundant during spermiogenesis of P. esculenta and may be related to the generation and maintenance of pseudopodia-like cytoplasmic protrusions and nuclear reshaping. The Pe-KIFC1 protein is conserved with a motor domain where microtubule and ATP binding sites are predicted, a coiled-coil domain and a divergent tail domain...
October 11, 2018: Gene
Shan Wang, Longjian Huang, Yong Zhang, Yuchen Peng, Xiaoliang Wang, Ying Peng
It has been reported that oxidative stress could result in damage to the developing brain. L-3-n-butylphthalide (L-NBP) could inhibit neuronal cell apoptosis and has neurogenesis effect in different animal and cellular models. However, whether L-NBP could protect the process of neurogenesis in neural stem cells (NSCs) against oxidative stress injury is still unclear. Here, in the present study, we evaluated the neuroprotective effect of L-NBP in NSCs against H2 O2 -induced injury and the possible mechanisms...
October 11, 2018: Neuroscience
Xiuli Jiang, Lei Jiang, Aijing Shan, Yutong Su, Yulong Cheng, Dalong Song, He Ji, Guang Ning, Weiqing Wang, Yanan Cao
BACKGROUND: Effective targeting therapies for common chronic liver disease nonalcoholic steatohepatitis (NASH) are in urgent need. MicroRNA-targeted therapeutics would be potentially an effective treatment strategy of hepatic diseases. Here we investigated the functional role of miR-221/222 and the therapeutic effects of antimiRs-221/222 in NASH mouse models. METHODS: We generated the miR-221/222flox/flox mice on a C57BL/6 J background and the hepatic miR-221/222 knockout (miR-221/222-LKO) mice...
October 10, 2018: EBioMedicine
Shan Chen, Hai Sen Xia, Feng Zhu, Guang Zhong Yin, Zheng Kang Qian, Cai Xia Jiang, Xiao Chu Gu, Xu Yuan Yin, Wen Jie Tang, Tian Hong Zhang, Ji Jun Wang, Qiu Fang Jia, Li Hui
Albumin is a metal-binding protein with free-radical scavenging properties and is recognized as a vital antioxidant. Moreover, an excess of free radicals may contribute to depressive symptoms and the psychopathology of psychiatric disorders. This study examined serum albumin levels, depressive symptoms, and their association in patients with schizophrenia. Thirty-four patients with schizophrenia (diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition) and 136 healthy controls were consecutively enrolled in this case-control study...
October 5, 2018: Psychiatry Research
Yulanticha Diaz Ahwalia Aziza, Shan-Tair Wang, Mei-Chih Huang
OBJECTIVE: The aim of this study was to investigate the needs and associating factors, psychological distress of parents when taking care of children with cancer in Indonesia. METHODS: A cross-sectional study was conducted among 100 parents of children with cancer from the pediatric ward of two hospitals in Indonesia. The parents were assessed using the Indonesian version of the Supportive Care Needs Survey for Partner and Caregiver (unmet needs) and the Hospital Anxiety Depression Scale (psychological distress)...
October 13, 2018: Psycho-oncology
Tongtong Wang, Qian Du, Xingchen Wu, Yingying Niu, Lijuan Guan, Zhenyu Wang, Xiaomin Zhao, Shan-Lu Liu, Dewen Tong, Yong Huang
No abstract text is available yet for this article.
November 1, 2018: Journal of Virology
Chun Sun, Lu Sun, Kai Jiang, Dong-Mei Gao, Xiao-Nan Kang, Cun Wang, Shu Zhang, Shan Huang, Xue Qin, Yan Li, Yin-Kun Liu
No abstract text is available yet for this article.
October 9, 2018: International Journal of Biochemistry & Cell Biology
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