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https://www.readbyqxmd.com/read/28641501/hematological-characterizations-and-molecular-diagnostic-aspects-of-hb-wiangpapao-%C3%AE-44-ce2-pro%C3%A2-ser-%C3%AE-1-ccg-tcg-hba1-c-133c-t-a-new-%C3%AE-globin-variant-found-in-a-pregnant-thai-woman
#1
Sitthichai Panyasai, Sakorn Pornprasert
We report the hematological parameters and provide a rapid molecular analysis method for detection of Hb Wiangpapao [α44(CE2)Pro→Ser, CCG>TCG; HBA1: c.133C>T], a new α-globin variant found in a pregnant Thai woman. Her red cell indices were measured by an automated blood counter. The results were: red blood cell (RBC) count 4.03 × 10(12)/L, Hb 13.1 (g/dL), packed cell volume (PCV) 0.39 L/L, mean corpuscular volume (MCV) 97.0 fL, mean corpuscular hemoglobin (Hb) (MCH) 32.5 pg, mean corpuscular Hb concentration (MCHC) 33...
June 23, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28637721/red-blood-cell-distribution-width-as-a-risk-factor-for-inhospital-mortality-in-obstetric-patients-admitted-to-an-intensive-care-unit-a-single-centre-retrospective-cohort-study
#2
Yufeng Chu, Zhongshang Yuan, Mei Meng, Haiyan Zhou, Chunting Wang, Gong Yang, Hongsheng Ren
BACKGROUND: Red blood cell distribution width (RDW) has been shown to predict mortality in critically ill patients. To our knowledge, whether or not RDW is associated with clinical outcomes of obstetric patients requiring critical care has not been evaluated. METHODS: This was a single centre, retrospective, observational study of obstetric patients admitted to the intensive care unit (ICU). Patients were excluded from the analysis if they had known haematological diseases or recently underwent blood transfusion...
June 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28635513/evaluation-of-platelet-indices-and-red-cell-distribution-width-as-new-biomarkers-for-the-diagnosis-of-acute-appendicitis
#3
Noha Boshnak, Mohamed Boshnaq, Hatem Elgohary
BACKGROUND: Debate around the value of laboratory tests in establishing the diagnosis of acute appendicitis (AA) still continues. This prospective study aimed to investigate the changes in mean platelet volume (MPV), platelet distribution width (PDW), and red cell distribution width (RDW) with the diagnosis of acute appendicitis. METHOD: 200 patients who underwent emergency appendectomy were included. According to postoperative histology, patients were divided into three groups: acute non-complicated, acute complicated appendicitis (positive appendicectomy groups), and negative appendectomy group...
February 16, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28625233/-elevation-of-red-cell-distribution-width-during-hospitalization-predicts-mortality-in-patients-with-sepsis
#4
Yan Gong, Xianming Long, Jun Jin, Xinjing Yang, Jianhong Fu, Fang Huang, Jian Huang, Qiang Guo, Jun Wang
OBJECTIVE: To investigate the association of red cell distribution width (RDW) with prognosis in patients with sepsis. METHODS: Patients with sepsis admitted to intensive care unit (ICU) of the First Hospital of Soochow University from January 2011 to December 2016 were enrolled. All clinical data were collected for participants, which mainly included basic data, main underlying disease, site of infection, acute physiology and chronic health evaluation II(APACHE II) score, blood routine test, biochemical test, blood gas analysis, coagulation index, procalcitonin (PCT), hospitalization days, and 28-day and 90-day mortality...
June 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28605139/clinical-implications-of-pretreatment-inflammatory-biomarkers-as-independent-prognostic-indicators-in-prostate-cancer
#5
Zhaohui Sun, Ying Ju, Fuyan Han, Xiya Sun, Fang Wang
OBJECTIVES: Research on the relationship between inflammatory biomarkers and malignant tumors has become a hotspot. Many studies have demonstrated that neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and red blood cell distribution width (RDW) could act as independent prognostic indicators for several solid tumors. This study aimed to evaluate the clinical implications of pretreatment inflammatory biomarkers, including NLR, PLR, and RDW as independent prognostic indicators in prostate cancer (PCa)...
June 12, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28600101/non-cardiac-factors-for-prediction-of-response-to-cardiac-resynchronization-therapy-the-value-of-baseline-and-of-serial-changes-in-red-cell-distribution-width
#6
Erberto Carluccio, Paolo Biagioli, Gianfranco Alunni, Adriano Murrone, Gianluca Zingarini, Stefano Coiro, Antonella D'Antonio, Anna Mengoni, Maria Francesca Cerasa, Giuseppe Ambrosio
BACKGROUND: Increased red blood cell distribution width (RDW) has been associated with poor outcome after cardiac resynchronization therapy (CRT). However, whether baseline RDW, and its serial changes after CRT implant, have incremental prognostic value is unknown. METHODS AND RESULTS: In 148 consecutive patients (age, 68±9years; 122 men) undergoing CRT, RDW was assessed before and 3months after implant. Patients were categorized according to baseline RDW (≤14...
June 2, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28597705/evaluation-of-applying-a-combination-of-red-cell-indexes-and-formulas-to-differentiate-%C3%AE-thalassemia-trait-from-iron-deficiency-anemia-in-the-thai-population
#7
Sakorn Pornprasert, Choosak Thongsat, Uraiporn Panyachadporn
Red cell indexes and formulas have been established as simple, fast, and inexpensive tools to differentiate β-thalassemia (β-thal) trait from iron deficiency anemia. However, none of them showed 100.0% sensitivity and specificity. Moreover, one index may show greater sensitivity and specificity in one population but is ineffective in another population. This study evaluated the diagnostic reliability of a combination of two red cell indexes [red blood cell (RBC) and red blood cell distribution width (RDW)] and nine formulas called '11T score' for differentiation of β-thal trait and iron deficiency anemia in the Thai population...
June 9, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28596707/red-cell-distribution-width-rdw-as-a-biomarker-for-respiratory-failure-in-a-pediatric-icu
#8
Tom Schepens, Jozef J De Dooy, Walter Verbrugghe, Philippe G Jorens
BACKGROUND: The red cell distribution width (RDW) is a widely available, inexpensive, and highly reproducible test that reflects the range of the red cell sizes. Any process that releases reticulocytes in the circulation will result in an increase in RDW. Elevated RDW values are linked to worsened pulmonary function in the adult population. We performed a retrospective cohort study to describe the association between RDW and respiratory failure in critically ill children in a in a pediatric intensive care unit (PICU) in a tertiary university hospital...
2017: Journal of Inflammation
https://www.readbyqxmd.com/read/28591051/association-between-red-blood-cell-distribution-width-and-henoch-schonlein-purpura-nephritis
#9
Hui Xu, Wei Li, Jian-Hua Mao, Yan-Xiang Pan
To investigate whether red blood cell distribution width (RDW) is a marker of the risk of Henoch-Schonlein purpura (HSP) nephritis (HSPN), a total of 669 HSP patients and 168 healthy controls were included in this retrospective study. Two hundred fifty-six (38.3%) of the patients had kidney involvement. Compared with the HSP group, RDW was significantly higher in the HSPN group (P < .001). Binary logistic regression identified that HSPN was independently associated with age, RDW, platelet, and total cholesterol (odds ratio = 1...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28583511/blood-count-values-and-ratios-for-predicting-sleep-apnea-in-obese-children
#10
Ibrahim Erdim, Omer Erdur, Fatih Oghan, Fatih Mete, Mustafa Celik
OBJECTIVES: To detect whether the mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are contributing factors in the diagnosis and severity of sleep apnea in obese children. INTRODUCTION: Obesity is a public health problem, and its prevalence increases daily. Although PSG is the gold standard test in the investigation of sleep apnea, the application of this test requires equipment, personnel, time, and cost. There is no simple laboratory test for diagnosing and determining the severity of sleep apnea...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28582601/hematologic-ris-for-healthy-water-buffaloes-bubalus-bubalis-in-southern-mexico
#11
Oswaldo M Torres-Chable, Nadia F Ojeda-Robertos, Alfonso J Chay-Canul, Jorge A Peralta-Torres, Carlos Luna-Palomera, Nahum Brindis-Vazquez, Bradley J Blitvich, Carlos Machain-Williams, Julian E Garcia-Rejon, Carlos M Baak-Baak, Karin S Dorman, Miguel A Alegria-Lopez
BACKGROUND: Baseline hematologic data are used by veterinarians and wildlife biologists to perform health assessments on target animal species. Hematologic measurements are influenced by various factors including geography. Baseline hematologic RIs have been established for domestic water buffaloes (Bubalus bubalis) from various countries in the Eastern Hemisphere, but these data are not readily available for the Western Hemisphere. OBJECTIVE: The aim of this study was to determine hematologic values for domestic water buffaloes from several commercial farms in southern Mexico...
June 5, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28578411/red-cell-distribution-width-as-a-significant-indicator-of-medication-and-prognosis-in-type-2-diabetic-patients
#12
Xiao-Fen Xiong, Yuan Yang, Xianghui Chen, Xuejing Zhu, Chun Hu, Yachun Han, Li Zhao, Fuyou Liu, Lin Sun
Whether red cell distribution width (RDW) can be a potential indicator for diabetic nephropathy (DN) is unknown. A total of 809 type 2 diabetes mellitus (T2D) patients were divided into 4 groups according to the quartiles (Q) of the RDW (%): Q1 ≤ 12.4 (n = 229), 12.4 < Q2 ≤ 12.9 (n = 202), 12.9 < Q3 < 13.5 (n = 168), Q4 ≥ 13.5 (n = 210). Results showed that the levels in Q4 group was higher in age, disease duration, systolic blood pressure, blood urea nitrogen, creatinine, uric acid and proteinuria but lower in hemoglobin, serum albumin and glycosylated hemoglobin compared to Q1 group...
June 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28577677/corrigendum-to-association-of-standard-clinical-and-laboratory-variables-with-red-blood-cell-distribution-width-rdw-am-heart-j-2016-22-28
#13
Patrícia O Guimarães, Jie-Lena Sun, Kristian Kragholm, Svati H Shah, Karen S Pieper, William E Kraus, Elizabeth R Hauser, Christopher B Granger, L Kristin Newby
No abstract text is available yet for this article.
June 2017: American Heart Journal
https://www.readbyqxmd.com/read/28576526/assessment-of-red-blood-cell-distribution-width-and-mean-platelet-volume-in-children-with-epistaxis
#14
Selin Üstün Bezgin, Taliye Çakabay, Işık Odaman Al
OBJECTIVE: This study aimed to investigate whether there is a relationship between red blood cell distribution width, mean platelet volume and epistaxis in children. METHODS: Between January 2015 and July 2016, 105 children who were referred to our clinic with epistaxis and 100 sex- and age-matched controls were retrospectively analyzed. Red blood cell distribution width (RDW) and mean platelet volume (MPV) values were determined in both groups. RESULTS: RDW values were found significantly (P < 0...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28556786/elevated-hemoglobin-level-is-associated-with-advanced-fibrosis-in-pediatric-non-alcoholic-fatty-liver-disease
#15
Valentina Giorgio, Antonella Mosca, Arianna Alterio, Anna Alisi, Antonio Grieco, Valerio Nobili, Luca Miele
OBJECTIVES: Hemoglobin (Hb) and red blood cell distribution width (RDW) have been reported to be a risk marker of metabolic syndrome (MS) and nonalcoholic fatty liver disease (NAFLD). No study exists on pediatric populations. We aimed to determine the association between hematological parameters, and the severity of disease in children with biopsy proven NAFLD. METHODS: 117 children (85 males, mean age 12 years) with ultrasound (US) evidence of NAFLD undergoing liver biopsy for diagnosis of non alcoholic steatohepatitis (NASH), were prospectively enrolled between January 2011 and May 2013 in the setting of a tertiary care centre...
April 27, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28555728/platelet-distribution-width-as-the-prognostic-marker-in-coronary-bifurcation-treatment
#16
Adam Kern, Robert J Gil, Krystian Bojko, Ewa Sienkiewicz, Beata Januszko-Giergielewicz, Jerzy Górny, Jacek Bil
INTRODUCTION: Mean platelet volume (MPV) was proved to be a reliable prognostic factor in cardiac patients. However, platelet distribution width (PDW) was disclosed to be more specific marker of platelet reactivity. The aim of study was to evaluate whether baseline PDW value can predict the outcome in patients undergoing percutaneous coronary interventions (PCI) with drug-eluting stent implantation within coronary bifurcation lesions. MATERIAL AND METHODS: It was a two-center observational study, which included patients who underwent PCI within bifurcation lesions between January 2014 and December 2014...
May 28, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28554095/the-association-between-red-cell-distribution-width-and-poor-outcomes-in-hospitalized-patients-with-influenza
#17
Guy Topaz, Yona Kitay-Cohen, Lee Peled, Wesal Gharra, Keren Kaminer, Mayan Eitan, Lamis Mahamid, Lotan Shilo
PURPOSE: To examine an association between red blood cell distribution width (RDW) and the prognosis of influenza patients. METHODS: We conducted a retrospective analysis of patients hospitalized with influenza during 2012-2015 in the internal medicine wards of one medical center. RDW measurements during hospitalization were analyzed. Primary outcome was complicated hospitalization (defined as at least one of: length of stay ≥7days, need for mechanical ventilation, septic shock, transfer to intensive-care, or 30-day mortality)...
May 23, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28546821/evaluation-of-neutrophil-lymphocyte-ratio-platelet-lymphocyte-ratio-and-red-blood-cell-distribution-width-platelet-ratio-for-diagnosis-of-premature-ovarian-insufficiency
#18
Gulsah Ilhan, Fatma Ferda Verit Atmaca, Esra Altan, Ali Galip Zebitay, Hamdullah Sozen, Hurkan Akyol, Meryem Kurek Eken
Objective: To evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and red blood cell distribution width (RDW) to platelet ratio (RPR)) can be used as reliable markers for the diagnosis of premature ovarian insufficiency (POI) and to determine if there is a relationship between these markers and follicle stimulating hormone (FSH), Anti-Müllerian Hormone (AMH) levels. Materials and methods: Written and electronic medical records were reviewed using searches for diagnoses with the terms of 'premature ovarian failure', 'premature ovarian insufficiency'...
December 2016: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/28544427/advanced-consumable-free-morphological-analysis-of-intact-red-blood-cells-by-a-compact-scanning-flow-cytometer
#19
K V Gilev, E S Yastrebova, D I Strokotov, M A Yurkin, N A Karmadonova, A V Chernyshev, V V Lomivorotov, V P Maltsev
Whereas modern automated blood cell analyzers measure the volume of individual red blood cells (RBCs), leading to four RBC indices (mean corpuscular volume, MCV; mean corpuscular hemoglobin, MCH; mean corpuscular hemoglobin concentration, MCHC; red cell distribution width, and RDW), the RBC shape has not been assessed by clinical screening tools. We applied the scanning flow cytometer (SFC) for complete characterization of intact RBC morphology in terms of diameter, maximal and minimal thicknesses, volume, surface area, sphericity index, spontaneous curvature, hemoglobin concentration, and content...
May 19, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28544156/m2bpgi-as-a-potential-diagnostic-tool-of-cirrhosis-in-chinese-patients-with-hepatitis-b-virus-infection
#20
Bin Wei, Shu Feng, Enqiang Chen, Dongdong Li, Tingting Wang, Yu Gou, Tingting Yang, Dongmei Zhang, Chuanmin Tao, Hong Tang
BACKGROUND: M2BPGi is a novel serum glycobiomarker of liver fibrosis. In this study, we aimed to evaluate the efficacy of M2BPGi for predicting liver fibrosis and disease progression in Chinese hepatitis B virus (HBV) infected patients. METHODS: We enrolled 228 HBV infected patients with different status of liver fibrosis diagnosed using FibroScan. We analyzed the diagnostic accuracy of M2BPGi, and compared it with AST-to-platelet ratio (APRI), FIB-4 index, AST to ALT ratio (AAR), and RDW to platelet ratio (RPR)...
May 24, 2017: Journal of Clinical Laboratory Analysis
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