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https://www.readbyqxmd.com/read/30098473/the-prospective-relationship-between-postpartum-ptsd-and-child-sleep-a-2-year-follow-up-study
#1
Susan Garthus-Niegel, Antje Horsch, Myriam Bickle Graz, Julia Martini, Tilmann von Soest, Kerstin Weidner, Malin Eberhard-Gran
BACKGROUND: The main aim of this study was to examine the prospective impact of maternal postpartum PTSD on several standardized child sleep variables two years postpartum in a large, population-based cohort of mothers. Moreover, we investigated the influence of numerous potential confounding maternal and child factors. Finally, we tested potential reverse temporal associations between child sleep eight weeks postpartum and maternal PTSD symptoms two years postpartum. METHODS: This study is part of the population-based Akershus Birth Cohort, a prospective cohort study at Akershus University Hospital, Norway...
July 24, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/30098263/-application-of-next-generation-sequencing-for-the-detection-of-chromosomal-aneuploidies-and-copy-number-variations-in-abortus-tissues
#2
Junkun Chen, Liqin Hu, Jingzhen Yang, Ping Liu
OBJECTIVE: To detect numerical chromosomal aberrations and copy number variations (CNVs) in abortus tissue samples with a benchtop semiconductor sequencing platform (SSP). METHODS: One hundred and forty patients with early spontaneous abortions at between 7 and 16 weeks were selected. Following DNA extraction, library preparation, high-throughput sequencing was carried out. RESULTS: Chromosomal anomalies were detected in 82 cases (58.57%), which included 67 aneuploidies and 15 CNVs...
August 10, 2018: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/30097044/preventing-at-risk-children-from-developing-antisocial-and-criminal-behaviour-a-longitudinal-study-examining-the-role-of-parenting-community-and-societal-factors-in-middle-childhood
#3
Madeleine Stevens
BACKGROUND: Many childhood risk factors are known to be associated with children's future antisocial and criminal behaviour, including children's conduct disorders and family difficulties such as parental substance abuse. Some families are involved with many different services but little is known about what middle childhood factors moderate the risk of poor outcomes. This paper reports the quantitative component of a mixed methods study investigating what factors can be addressed to help families improve children's outcomes in the longer term...
August 10, 2018: BMC Psychology
https://www.readbyqxmd.com/read/30096612/associations-between-maternal-residential-proximity-to-air-emissions-from-industrial-facilities-and-low-birth-weight-in-texas-usa
#4
Xi Gong, Yan Lin, Michelle L Bell, F Benjamin Zhan
BACKGROUND: Most previous studies examining associations between maternal exposures to air pollutants during pregnancy and low birth weight (LBW) in offspring focused on criteria air pollutants (PM2.5 , PM10 , O3 , NO2 , SO2 , CO, and Pb). The relationship between non-criteria air pollutants and LBW is understudied and requires greater coverage. OBJECTIVES: This study investigated associations between maternal residential exposure to industrial air pollutants during pregnancy and LBW in offspring...
August 7, 2018: Environment International
https://www.readbyqxmd.com/read/30096609/maternal-cell-phone-use-during-pregnancy-and-child-cognition-at-age-5-years-in-3-birth-cohorts
#5
Madhuri Sudan, Laura Ellen Birks, Juan J Aurrekoetxea, Amparo Ferrero, Mara Gallastegi, Mònica Guxens, Mina Ha, Hyungryul Lim, Jorn Olsen, Llúcia González-Safont, Martine Vrijheid, Leeka Kheifets
BACKGROUND: There have been few studies of children's cognitive development in relation to mothers' cell phone use, and most were limited to outcomes at age 3 years or younger. We examined the relationship between maternal cell phone use during pregnancy and cognitive performance in 5-year old children. METHODS: This study included data from 3 birth cohorts: the Danish National Birth Cohort (DNBC) (n = 1209), Spanish Environment and Childhood Project (INMA) (n = 1383), and Korean Mothers and Children's Environment Health Study (MOCEH) (n = 497)...
August 7, 2018: Environment International
https://www.readbyqxmd.com/read/30096149/transcription-factor-ascl2-is-required-for-development-of-the-glycogen-trophoblast-cell-lineage
#6
Aaron B Bogutz, Rosemary Oh-McGinnis, Karen J Jacob, Rita Ho-Lau, Ting Gu, Marina Gertsenstein, Andras Nagy, Louis Lefebvre
The basic helix-loop-helix (bHLH) transcription factor ASCL2 plays essential roles in diploid multipotent trophoblast progenitors, intestinal stem cells, follicular T-helper cells, as well as during epidermal development and myogenesis. During early development, Ascl2 expression is regulated by genomic imprinting and only the maternally inherited allele is transcriptionally active in trophoblast. The paternal allele-specific silencing of Ascl2 requires expression of the long non-coding RNA Kcnq1ot1 in cis and the deposition of repressive histone marks...
August 10, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/30095996/cardiac-myocyte-proliferation-and-maturation-near-term-is-inhibited-by-early-gestation-maternal-testosterone-exposure
#7
Sonnet S Jonker, Samantha Louey, Charles E Roselli
Polycystic ovary syndrome (PCOS) is a complex and common disorder in women, and those affected experience an increased burden of cardiovascular disease. It is an intergenerational syndrome, as affected women with high androgen levels during pregnancy "program" fetal development, leading to a similar phenotype in their female offspring. The effect of excess maternal testosterone exposure on fetal cardiomyocyte growth and maturation is unknown. METHODS Pregnant ewes received biweekly injections of vehicle (Control) or 100 mg testosterone propionate between 30-59 days of gestation (dGA; Early T) or 60-90 dGA (Late T)...
August 10, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/30095570/seasonal-variations-in-microtia-of-chinese-population
#8
Jin-Tian Hu, Qi Chen, Hui-Ying Song, Yi-Lin Cao, Yong-Biao Zhang, Xu Zhou, Tun Liu, Qing-Guo Zhang
BACKGROUND: Seasonality of congenital birth defect could help to identify environmental risk factors. Data concerning the seasonality of the prevalence of microtia are little. This article aims to determine whether births of microtia follow a certain pattern. METHODS: Data were obtained from 2669 patients with microtia who were admitted to Second Ear Reconstruction Center of Plastic Surgery Hospital, Chinese Academy of Medical Science from January 2007 to December 2013...
August 7, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/30095392/early-life-obesity-increases-the-risk-for-asthma-in-san-francisco-born-latina-girls
#9
Margaret McCallister, Rosalinda Medrano, Janet Wojcicki
BACKGROUND: Previous studies showed that youths who are obese are more likely to have asthma; however, some studies found important sex differences in the risk for asthma. METHODS: We retrospectively assessed the asthma incidence in a Latino cohort of children recruited from birth and followed up until 9 years of age. We subsequently assessed risk factors for asthma and for an early asthma (defined as <4 years of age) diagnosis in relation to obesity. Asthma was assessed via maternal reports and medical records review of the children at 9 years of age...
July 1, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/30094895/periodontal-diseases-and-adverse-pregnancy-outcomes
#10
Shihoko Komine-Aizawa, Sohichi Aizawa, Satoshi Hayakawa
From last decade of the 20th century, numerous epidemiological studies and intervention trials have attempted to prove the relationships between maternal periodontal diseases and adverse pregnancy outcomes (APO). Periodontal diseases are considered a risk factor for APO, including preterm birth, fetal growth restriction, low birthweight, pre-eclampsia and gestational diabetes. However, the efficacy of periodontal treatment during pregnancy is controversial. Two pathogenic mechanisms might explain the potential effect of periodontal diseases on pregnancy outcomes...
August 9, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/30094758/sb203580-attenuates-acute-lung-injury-and-inflammation-in-rats-with-acute-pancreatitis-in-pregnancy
#11
Yu Zhou, Hongmiao Xia, Liang Zhao, Fangchao Mei, Man Li, Yundong You, Kailiang Zhao, Weixing Wang
Acute pancreatitis in pregnancy (APIP) can lead to multiple maternal and fetal organ injury and mitogen-activated protein kinase (MAPK) signaling pathway may be involved in it; however, whether APIP can result in acute lung injury and P38MAPK signaling pathway is involved in the pathogenesis has not been elucidated. The present study was undertaken to investigate the participation of P38MAPK signaling pathway and the protective effect of SB203580, an inhibitor of P38MAPK on acute lung injury induced by APIP...
August 9, 2018: Inflammopharmacology
https://www.readbyqxmd.com/read/30094645/prenatal-stress-maternal-immune-dysregulation-and-their-association-with-autism-spectrum-disorders
#12
REVIEW
David Q Beversdorf, Hanna E Stevens, Karen L Jones
PURPOSE OF REVIEW: While genetic factors are a major etiological contributor to autism spectrum disorder (ASD), evidence also supports a role for environmental factors. Herein, we will discuss two such factors that have been associated with a significant proportion of ASD risk: prenatal stress exposure and maternal immune dysregulation, and how sex and gender relate to these factors. RECENT FINDINGS: Recent evidence suggests that maternal stress susceptibility interacts with prenatal stress exposure to affect offspring neurodevelopment...
August 9, 2018: Current Psychiatry Reports
https://www.readbyqxmd.com/read/30094531/physical-activity-patterns-and-correlates-of-9-month-old-chinese-infants-in-the-macau-population
#13
Zhenzhen Jia, Joni Zhang, Dulce Trindade, Tanja Sobko
Objectives Many obesity-related chronic diseases originate from unhealthy childhood habits. The aim of this study was to describe 9-month-old infants' physical activity levels and patterns and to examine the correlates. Understanding these factors is necessary for improving the effectiveness of physical activity intervention programs for infants. Methods In total, 143 infant-mother dyads from Macau, SAR China, participated in this study. Physical activity (PA) was assessed by using the Actigraph GT3X+ accelerometer and the demographic variables were collected by questionnaires...
August 9, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/30094052/recent-trends-risk-factors-and-disparities-in-low-birth-weight-in-california-2005-2014-a-retrospective-study
#14
Anura W G Ratnasiri, Steven S Parry, Vivi N Arief, Ian H DeLacy, Laura A Halliday, Ralph J DiLibero, Kaye E Basford
Background: Low birth weight (LBW) is a leading risk factor for infant morbidity and mortality in the United States. There are large disparities in the prevalence of LBW by race and ethnicity, especially between African American and White women. Despite extensive research, the practice of clinical and public health, and policies devoted to reducing the number of LBW infants, the prevalence of LBW has remained unacceptably and consistently high. There have been few detailed studies identifying the factors associated with LBW in California, which is home to a highly diverse population...
2018: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/30093745/screening-for-mental-health-disorders-among-pregnant-women-availing-antenatal-care-at-a-government-maternity-hospital-in-bengaluru-city
#15
Avita Rose Johnson, Meera George, B Ramakrishna Goud, T Sulekha
Introduction: Antepartum anxiety and depression are two of the most common risk factors for the development of postpartum depression. Women are at a higher risk of developing depression and suffering from mental disorders during pregnancy and the postnatal period. Psychopathological symptoms during pregnancy have physiological consequences for the fetus, such as impaired blood flow leading to low birth weight, as well as cognitive delay and behavioral problems. Objectives: To screen antenatal women for common mental health disorders and to determine the factors associated with mental health disorders during pregnancy...
July 2018: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/30093348/gestational-weight-gain-and-unplanned-or-emergency-cesarean-delivery-in-the-united-states
#16
Zelalem T Haile, Bhakti Chavan, Asli K Teweldeberhan, Ilana R Azulay Chertok, John Francescon
BACKGROUND: In the United States, the rates of cesarean delivery are well above the World Health Organization recommended target. Although obesity is a widely established risk factor for cesarean delivery, there is limited population-based research that examines the relationship between gestational weight gain and cesarean delivery. OBJECTIVE: To determine the association between gestational weight gain and unplanned or emergency cesarean delivery. METHODS: We examined 2107 mothers from the Infant Feeding Practices Study II 2005-2007...
August 6, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/30092923/perinatal-sleep-problems-causes-complications-and-management
#17
REVIEW
Allison K Wilkerson, Thomas W Uhde
Changes in sleep are ubiquitous in the perinatal period and it is important to be able to determine when these changes are significant enough to indicate sleep deficiency associated with increased risk for poor maternal and infant outcomes. Guidelines for identifying sleep deficiency include insomnia symptoms, excessively shortened sleep duration, and perception of insufficient or nonrestful sleep. Causes and complicating factors related to such sleep problems have been well-documented and are used to tailor behavioral and pharmacologic treatments for women who are pregnant or in the early postpartum period...
September 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/30092662/prevalence-and-relevant-factors-of-anxiety-and-depression-among-pregnant-women-in-a-cohort-study-from-south-east-china
#18
Youding Zhang, Xiamusiye Muyiduli, Shuojia Wang, Wen Jiang, Jinhua Wu, Minchao Li, Minjia Mo, Shuying Jiang, Zhaopin Wang, Bule Shao, Yu Shen, Yunxian Yu
OBJECTIVE: To describe the prevalence rate of prenatal anxiety and depression among pregnant women in a prospective cohort study and to explore the relevant factors of anxiety and depression during each trimester. METHODS: Pregnant women were recruited into the Zhoushan Pregnant Women Cohort at Zhoushan Maternal and Child Care Hospital from September 2011 to March 2015. A self-made questionnaire was used to collect information about social demography, reproductive history, physical activity, and life behaviour at the first, second and third trimester, respectively...
August 9, 2018: Journal of Reproductive and Infant Psychology
https://www.readbyqxmd.com/read/30092608/bioactive-components-in-human-milk-are-differentially-associated-with-rates-of-lean-and-fat-mass-deposition-in-infants-of-mothers-with-normal-vs-elevated-bmi
#19
B E Young, C Levek, R M Reynolds, M C Rudolph, P MacLean, T L Hernandez, J E Friedman, N F Krebs
OBJECTIVE: To model breastfed infant growth and body composition patterns over the first 4 months with multiple bioactive components of human milk (HM) and clinical factors (including maternal BMI status), which are related to growth. METHODS: Longitudinal observation of infant growth and body composition from 0 to 4 months among 41 predominantly breastfed infants (25 mothers of Normal-weight and 16 mothers with overweight/obesity). Fasted morning HM samples were collected at 5 time-points...
August 9, 2018: Pediatric Obesity
https://www.readbyqxmd.com/read/30092087/trends-and-factors-associated-with-pregnancies-among-adolescent-women-in-nepal-pooled-analysis-of-nepal-demographic-and-health-surveys-2006-2011-and-2016
#20
Samikshya Poudel, Nawaraj Upadhaya, Resham Bahadur Khatri, Pramesh Raj Ghimire
INTRODUCTION: Adolescent pregnancy is a significant cost to mother, newborn, and their family and society. Despite the enormous health and social impact of adolescent pregnancy, there is a dearth of nationally representative studies on factors associated with adolescent pregnancies in Nepal. Therefore, this study aimed to examine trends and factors associated with adolescent pregnancies in Nepal, using pooled data of three nationally representative demographic surveys. METHODS: Data for this study was derived from the recent three consecutive (2006, 2011 and 2016) Nepal Demographic and Health Surveys (NDHS)...
2018: PloS One
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