Mohammad Salem Baba, Bashir Ahmad Laway, Raiz Ahmad Misgar, Arshad Iqbal Wani, Mir Iftikhar Bashir, Imtiyaz Ahmad Bhat, Malik Gawharul Haq, Zafar Amin Shah
BACKGROUND: Hyperprolactinemia is associated with obesity, dyslipidemia, insulin resistance, and low-grade inflammation which may promote endothelial dysfunction (EnD). Limited work has been done on EnD in prolactinomas and we, therefore, studied serum markers of inflammation and EnD in patients with prolactinomas before and after treatment with dopamine agonists. METHODOLOGY: Fifty-six treatment naïve patients with prolactinomas and fifty-three (apparently healthy age and sex-matched) controls were enrolled in the study and subjected to clinical assessment and laboratory investigations including blood glucose, total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, urea, creatinine, uric acid, erythrocyte sedimentation rate (ESR), highly sensitive C-reactive protein (hsCRP) and markers of EnD i...
2023: Indian Journal of Endocrinology and Metabolism