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OTC antibiotic

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https://www.readbyqxmd.com/read/30103200/evaluation-of-antibiotic-oxytetracycline-removal-in-water-using-a-gas-phase-dielectric-barrier-discharge-plasma
#1
Shoufeng Tang, Deling Yuan, Yandi Rao, Jingyi Zhang, Ying Qu, Jianmin Gu
Degradation of oxytetracycline (OTC), a primary member of antibiotics in water, was performed by a gas phase dielectric barrier discharge (GPDBD) plasma reactor. The influences of operation conditions including applied voltages, air bubbling rates, initial OTC concentrations and initial pH values on OTC abatement were investigated respectively. The results showed that the decontamination process can be fitted by first order kinetics, and the removal ratio and rate were affected obviously by those parameters...
August 10, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/30098505/oxytetracycline-effects-in-specific-biochemical-pathways-of-detoxification-neurotransmission-and-energy-production-in-oncorhynchus-mykiss
#2
S Rodrigues, S C Antunes, A T Correia, B Nunes
Oxytetracycline (OTC) is a tetracycline antibiotic, widely used in human and veterinary medicines, including in aquaculture. Given this use, OTC has been detected in different aquatic environments. Some recent works have demonstrated unintentional biological activity of OTC in non-target aquatic organisms. This study investigated the acute and chronic effects of OTC on the physiology of the fish species Oncorhynchus mykiss (rainbow trout), namely through the quantification of the activity of enzymes involved in different biochemical pathways, such as detoxification (phase II - glutathione S-transferases - GSTs, uridine-diphosphate-glucuronosyltransferases - UGTs), neurotransmission (acetylcholinesterase - AChE) and energy production (lactate dehydrogenase - LDH)...
August 8, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/30075378/the-role-of-antibiotics-in-mercury-methylation-in-marine-sediments
#3
Peng Liang, Shengchun Wu, Chan Zhang, Jialin Xu, Peter Christie, Jin Zhang, Yucheng Cao
The role of antibiotics commonly used in fish culture activities in methylmercury (MeHg) formation in mariculture sediments (MS) and in reference sediments (RS) was studied using simulation microcosms. MS and RS were split into three equal batches. Two batches were spiked with Hg(NO3 )2 aqueous solution at levels of 2 and 8 mg kg-1 (dry weight basis) and the remainder served as a control batch. Tetracycline (TC) and oxytetracycline (OTC) (2.5 g and 10 g of each) were added to each treatment. Sediment THg concentration decreased during the culture period possibly due to complexation of Hg with the antibiotics resulting in the dissolution of Hg compounds from the sediment...
July 26, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/30073592/phosphate-affects-adsorption-and-desorption-of-oxytetracycline-in-the-seawater-sediment-systems
#4
Jia Li, Hua Zhang, Guodong Yuan
The fate and transport of antibiotics in the aquatic environment are usually influenced by the combined effects of environmental factors. In this study, batch-type experiments were conducted to investigate the combined effects of phosphate and salinity on oxytetracycline (OTC) adsorption on, and desorption from, two marine sediments. Pseudo-second-order kinetic model fitted the kinetic data better than pseudo-first-order model. The pseudo-second-order kinetic rate (k2 ) of OTC increased significantly with increasing phosphate concentrations...
August 2, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/30029318/spatiotemporal-profile-of-tetracycline-and-sulfonamide-and-their-resistance-on-a-catchment-scale
#5
Yan Xu, Changsheng Guo, Jiapei Lv, Song Hou, Yi Luo, Yuan Zhang, Jian Xu
Tetracyclines and sulfonamides are the two classes of antibiotics commonly used in the medical, industrial and agricultural activities. Their extensive usage has caused the proliferation and propagation of resistant bacteria (ARB) and resistance genes (ARGs) in the environment. In this study, the occurrence and distribution of tetracyclines (TC, OTC and CTC) and sulfonamides (SMX, SCX and TMP), their associated ARB and ARGs were quantified in water and sediments collected from the mainstream of Liaohe River, northeast China...
October 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29996545/characterizing-the-interaction-between-antibiotics-and-humic-acid-by-fluorescence-quenching-method
#6
Runze Wang, Shengke Yang, Jie Fang, Zongzhou Wang, Yangyang Chen, Dan Zhang, Chunyan Yang
The method of Three-Dimensional Excitation Emission Matrix Fluorescence Spectrophotometer was used to identify the interaction mechanism between humic acid (HA) and antibiotics. The effects of antibiotic concentration, temperature, and pH on the bonding strength between HA and antibiotics were investigated. The results showed that with the increase of antibiotics concentration, the quenching effect on HA was enhanced. The quenching of HA by both oxytetracycline (OTC) and sulfadiazine (SD) is a single static quenching of the complexes, and the interaction forces are mainly a hydrogen bond and the van der Waals force...
July 10, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29987471/the-joint-toxicity-effect-of-five-antibiotics-and-dibutyl-phthalate-to-luminescent-bacteria-vibrio-fischeri
#7
Sheng Wei, Fenghe Wang, Yajun Chen, Tao Lan, Shengtian Zhang
Antibiotics and phthalate esters are two kinds of emerging pollutants and are ubiquitous in the aquatic ecosystem. To date, few studies analyzed the combined toxicity of the mixtures of antibiotics and phthalate esters, and their joint toxicity effect mode remains unknown. Here, we investigated the single and joint toxicity of dibutyl phthalate (DBP) and five antibiotics, namely, oxytetracycline hydrochloride (OTC), chlortetracycline hydrochloride (CTC), sulfamethazine (SMZ), sulfamerazine (SMR), and sulfadiazine (SD), to luminescent bacteria of Vibrio fischeri...
July 10, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29976180/promoting-quality-use-of-medicines-in-south-east-asia-reports-from-country-situational-analyses
#8
Kathleen Anne Holloway, Anita Kotwani, Gitanjali Batmanabane, Budiono Santoso, Sauwakon Ratanawijitrasin, David Henry
BACKGROUND: Irrational use of medicines is widespread in the South-East Asia Region (SEAR), where policy implementation to encourage quality use of medicines (QUM) is often low. The aim was to determine whether public-sector QUM is better in SEAR countries implementing essential medicines (EM) policies than in those not implementing them. METHODS: Data on six QUM indicators and 25 EM policies were extracted from situational analysis reports of 20 country (2-week) visits made during 2010-2015...
July 5, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29965628/-distribution-and-treatment-of-antibiotics-in-typical-wwtps-in-small-towns-in-china
#9
Yu-Feng Chai, Yu-Xiu Zhang, Mei-Xue Chen, Rui Wang, Meng-Meng Liu, Jia-Xi Zheng, Yuan-Song Wei
As a new, persistent pollutant in the environment, antibiotics are one of the most important pollutants in sewage treatment plants. The objective of this work was to investigate the concentration distribution and removal efficiency of antibiotics for three typical wastewater treatment technologies applied in small towns (CASS, A2 /O, and Orbal oxidation ditch) using solid phase extraction-liquid chromatography-tandem mass spectrometry. Sixteen typical antibiotics, including four tetracyclines, three β -lactams, four macrolides, three quinolones, and two sulfonamides, were analyzed in the influent and effluent...
June 8, 2018: Huan Jing Ke Xue= Huanjing Kexue
https://www.readbyqxmd.com/read/29965486/-oxytetracycline-wastewater-treatment-in-microbial-fuel-cells-and-the-analysis-of-microbial-communities
#10
Wei-Fu Yan, Yong Xiao, Shu-Hua Wang, Rui Ding, Feng Zhao
Oxytetracycline (OTC) as an important broad spectrum antibiotic has been widely used in animal husbandry. However, the abuse of OTC not only has a direct adverse impact on ecosystems, but also exacerbates the appearance of antibiotic resistance bacteria and antibiotic resistance genes. OTC-containing wastewater was treated using microbial fuel cells (MFCs), and the removal efficiency of OTC in MFCs in different operation periods was investigated. Result showed that the removal efficiency of 10 mg·L-1 OTC by MFCs within 132 h was up to 99...
March 8, 2018: Huan Jing Ke Xue= Huanjing Kexue
https://www.readbyqxmd.com/read/29964860/-effects-of-tetracycline-antibiotics-on-growth-and-characteristics-of-enrichment-and-transformation-in-two-vegetables
#11
Sun-Lin Chi, Wei-Zhong Wang, Wei-Hong Xu, Tao Li, Yan-Hua Li, Chun-Lai Zhang
Pot experiments were carried out to study different levels (0, 50, and 150 mg·kg-1 ) of three tetracycline antibiotics[tetracycline (TC), oxytetracycline (OTC), and chlortetracycline (CTC)] on the growth, concentration of tetracycline antibiotics, and their characteristics of enrichment and transformation in two kinds of vegetables (lettuce and Chinese cabbage). The results showed that the fresh weight of shoots and roots of lettuce decreased by 1.56%-26.84% and 17.36%-51.04%, respectively, when exposed to tetracycline antibiotics compared to the control, while the fresh weight of shoots and roots of Chinese cabbage increased by 3...
February 8, 2018: Huan Jing Ke Xue= Huanjing Kexue
https://www.readbyqxmd.com/read/29882793/fast-response-and-reusable-oxytetracycline-colorimetric-strips-based-on-nickel-ii-ions-immobilized-carboxymethylcellulose-polyacrylonitrile-nanofibrous-membranes
#12
Mohammed Awad Abedalwafa, Yan Li, De Li, Xiaojun Lv, Lu Wang
Driven by economic interests, the abuse of antibiotics has become a significant concern for humans worldwide. As one of the most commonly used antibiotics, oxytetracycline (OTC) residue in animal-derived foods occurs occasionally, which has caused danger to humanity. However, there is still no simple and efficient solution to detect OTC residue. Here, an easily-operated colorimetric strategy for OTC detection was developed based on nickel ions (Ni2+ ) immobilized carboxymethylcellulose/polyacrylonitrile nanofibrous membranes (Ni@CMC/PAN NFMs)...
June 6, 2018: Materials
https://www.readbyqxmd.com/read/29807293/factors-influencing-the-removal-of-antibiotic-resistant-bacteria-and-antibiotic-resistance-genes-by-the-electrokinetic-treatment
#13
Hongna Li, Binxu Li, Zhiguo Zhang, Yunlong Tian, Jing Ye, Xiwu Lv, Changxiong Zhu
The performance of the electrokinetic remediation process on the removal of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) was evaluated with different influencing factors. With chlortetracycline (CTC), oxytetracycline (OTC), and tetracycline (TC) as template chemicals, the removal of both ARB and ARGs was enhanced with the increase of voltage gradient (0.4-1.2 V cm-1 ) and prolonged reaction time (3-14 d). The greatest removal (26.01-31.48% for ARB, 37.93-83.10% for ARGs) was obtained applying a voltage of 1...
September 30, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29803848/microbial-shifts-in-the-swine-nasal-microbiota-in-response-to-parenteral-antimicrobial-administration
#14
Mohamed Zeineldin, Brian Aldridge, Benjamin Blair, Katherine Kancer, James Lowe
The continuous administration of antimicrobials in swine production has been widely criticized with the increase of antimicrobial-resistant bacteria and dysbiosis of the beneficial microbial communities. While an increasing number of studies investigate the effects of antimicrobial administration on swine gastrointestinal microbiota biodiversity, the impact of their use on the composition and diversity of nasal microbial communities has not been widely explored. The objective of this study was to characterize the short-term impact of different parenteral antibiotics administration on the composition and diversity of nasal microbial communities in growing pigs...
August 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29803031/degradation-of-oxytetracycline-under-autotrophic-nitrifying-conditions-in-a-membrane-aerated-biofilm-reactor-and-community-fingerprinting
#15
Aytekin Çelik, Eoin Casey, Halil Hasar
Pharmaceuticals in waterbodies are a growing concern due to their extensive uses and adverse effects on aquatic life. Oxytetracycline (OTC) is one of tetracycline antibiotic group used for treatment of animals and humans. This study evaluates the simultaneous oxidation of OTC and ammonium under autotrophic nitrifying conditions by using a membrane aerated biofilm reactor (MABR) as it provides an appropriate environment for the antibiotic-degrading bacteria. The results showed that MABR achieved fluxes of 1...
August 15, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29766261/comprehensive-evaluation-of-autohydrogenotrophic-membrane-biofilm-reactor-treating-otc-enriched-water-medium
#16
Aytekin Celik, Müslün Sara Tunc, Ozge Hanay, Ergin Taskan, Halil Hasar
In the recent years, there has been considerable debate about the potential impacts of antibiotics present in various environments on the public health and ecology. Oxytetracycline (OTC) is one of tetracycline antibiotic group used for growth and treatment of animals and humans. In this study, OTC and nitrate (NO3 -N) were simultaneously reduced using a hydrogen-based membrane biofilm reactor (H2 -MBfR). The system successfully accomplished OTC and nitrate removals. The fluxes of OTC and NO3 -N were 8.96 mg OTC/m2  day and 1100 mg N/m2  day, respectively...
May 15, 2018: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/29763802/sorption-of-norfloxacin-sulfamerazine-and-oxytetracycline-by-koh-modified-biochar-under-single-and-ternary-systems
#17
Jiwei Luo, Xue Li, Chengjun Ge, Karin Müller, Huamei Yu, Peng Huang, Jiatong Li, Daniel C W Tsang, Nanthi S Bolan, Jörg Rinklebe, Hailong Wang
Pollution of water by single antibiotics has been investigated in depth. However, in reality, a wide range of different contaminants is often mixed in the aquatic environment (contaminant cocktail). Here, single and competitive sorption dynamics of ionizable norfloxacin (NOR), sulfamerazine (SMR) and oxytetracycline (OTC) by both pristine and modified biochars were investigated. Sorption kinetics of the three antibiotics was faster in ternary-solute than single-solute system. Sorption efficiency was enhanced in the competitive system for NOR by the pristine biochar, and for OTC by both the pristine biochar and the modified biochar, while SMR sorption by the pristine biochar and the KOH-modified biochar was inhibited...
September 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29710673/biotic-and-abiotic-dissipation-of-tetracyclines-using-simulated-sunlight-and-in-the-dark
#18
M Conde-Cid, D Fernández-Calviño, J C Nóvoa-Muñoz, M Arias-Estévez, M Díaz-Raviña, M J Fernández-Sanjurjo, A Núñez-Delgado, E Álvarez-Rodríguez
Veterinary antibiotics reaching soils and water bodies are considered emerging pollutants deserving special attention. In this work, dissipation of tetracycline (TC), oxytetracycline (OTC) and chlortetracycline (CTC) is investigated. Dissipation experiments in filtered water, using simulated sunlight, resulted in the following degradation sequence: TC < OTC ≈ CTC, with half-life values of 229, 101 and 104 min, respectively; however, no dissipation took place in the dark. Dissipation of the three tetracyclines in culture medium and with simulated sunlight was much higher, giving the sequence TC ≈ OTC < CTC, with half-lives of 9, 10 and 7 min, respectively; in the dark, TC and OTC did not suffer dissipation, but it was around 28% for CTC at the end of the experiment (480 min)...
September 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29674151/use-of-a-hyperaccumulator-and-biochar-to-remediate-an-acid-soil-highly-contaminated-with-trace-metals-and-or-oxytetracycline
#19
Zhu Li, Mingyun Jia, Peter Christie, Shafaqat Ali, Longhua Wu
Biochars and hyperaccumulators have been widely used for the remediation of trace metal contaminated soils through immobilization and phytoextraction. These two options have rarely been used simultaneously despite their potential to achieve a greater decline in trace metal availability and higher removal efficiency in polluted soils. This study investigated the combined effects of biochar and the cadmium/zinc (Cd/Zn) hyperaccumulator Sedum plumbizincicola in a pot experiment and examined the effect of an antibiotic (oxytetracycline, OTC) in an acid soil spiked with Cd/Zn alone and with OTC...
August 2018: Chemosphere
https://www.readbyqxmd.com/read/29665533/the-effect-of-antibiotics-on-the-persistence-of-herbicides-in-soil-under-the-combined-pollution
#20
Wenqi Jiang, Jing Gao, Zheng Cheng, Peng Wang, Zhiqiang Zhou, Donghui Liu
Antibiotic contamination in agricultural lands through manure application causes changes in soil enzyme activity and the abundance of microbes, which may affect the fate of agrochemicals. A clear understanding of antibiotic-pesticide interactions is very limited. The objective of this study was to investigate the effect of oxytetracycline (OTC) on the persistence of triazine and chloroacetanilide herbicides in soil under a combined application scenario. Soil enzyme activity and the abundance of soil microbes disturbed by OTC were measured...
August 2018: Chemosphere
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