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https://www.readbyqxmd.com/read/29667413/peroral-endoscopic-myotomy-in-pediatric-jackhammer-esophagus
#1
Rosa Ramos, Martín Alejandro Guidi, Maria Kakisu, Ana Rocca, Paulo Sakai
The jackhammer esophagus is a rare hypercontractile disorder and diagnosis is based on high-resolution manometry. Peroral endoscopic myotomy (POEM) of the spastic esophagus segments has been described. We report a pediatric patient with jackhammer esophagus that was treated endoscopically.
April 18, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29660156/evaluation-of-symptomatic-esophagogastric-junction-outflow-obstruction
#2
Andrew Ming Liang Ong, Vikneswaran Namasivayam, Yu Tien Wang
BACKGROUND: Esophagogastric junction outflow obstruction (EGJOO) may be due to anatomical abnormalities but it is unclear how to evaluate them after high resolution manometry (HRM). We aimed to determine 1) clinical and HRM parameters differentiating anatomical EGJOO from functional EGJOO, 2) investigations chosen and yield for anatomical EGJOO and 3) clinical outcomes of functional EGJOO. METHODS: Medical records of consecutive patients with symptomatic EGJOO from February 2012 to December 2015 were reviewed...
April 16, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29657705/laparoscopic-transhiatal-resection-of-a-large-mid-esophageal-diverticulum-a-case-report
#3
Tomislav Tokic, Iva Kirac, Davor Hrabar, Branko Troskot, Miroslav Bekavac-Beslin
This is a description of transhiatal laparoscopic approach for mid-esophageal diverticulum. Traditionally mid-esophageal diverticula are approached by thoracotomy or thoracoscopy, with the laparoscopic technique being reserved for epiphrenic diverticula. A 78-year-old Caucasian female with a secondary dilatative ischemic cardiomyopathy presented with dysphagia, tenderness in the epigastrium and a considerable weight loss. A large mid-esophageal diverticulum was found on barium swallow and confirmed by CT scan...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29656582/hyperactive-cyclic-motor-activity-in-the-distal-colon-after-colonic-surgery-as-defined-by-high-resolution-colonic-manometry
#4
R Vather, G O'Grady, A Y Lin, P Du, C I Wells, D Rowbotham, J Arkwright, L K Cheng, P G Dinning, I P Bissett
BACKGROUND: Recovery after colonic surgery is invariably delayed by disturbed gut motility. It is commonly assumed that colonic motility becomes quiescent after surgery, but this hypothesis has not been evaluated rigorously. This study quantified colonic motility through the early postoperative period using high-resolution colonic manometry. METHODS: Fibre-optic colonic manometry was performed continuously before, during and after surgery in the left colon and rectum of patients undergoing right hemicolectomy, and in healthy controls...
April 14, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29652729/anorectal-manometry-may-reduce-the-number-of-rectal-suction-biopsy-procedures-needed-to-diagnose-hirschsprung-s-disease
#5
Rob J Meinds, Monika Trzpis, Paul M A Broens
OBJECTIVES: To evaluate whether anorectal manometry (ARM), which is used to test the rectoanal inhibitory reflex (RAIR), is a safe alternative for reducing the number of invasive rectal suction biopsy (RSB) procedures needed to diagnose Hirschsprung's disease (HD). METHODS: Between 2010 and 2017, we prospectively collected the ARM results of 105 patients suspected of having HD. Following the outcome, the patients either underwent additional tests to confirm HD or they were treated conservatively...
April 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29644765/correlation-between-novel-3d-high-resolution-manometry-esophagogastric-junction-metrics-and-ph-metry-in-reflux-disease-patients
#6
Y Xiao, Z Lin, Y Li, J E Pandolfino, M Chen, P J Kahrilas
BACKGROUND AND AIMS: We recently developed 2 novel 3D high-resolution manometry (HRM) metrics of esophagogastric junction (EGJ) contractility to differentiate the lower esophageal sphincter (LES) and crural diaphragm (CD) elements of EGJ pressure. This study aimed to compare these metrics to the EGJ-contractile integral (EGJ-CI) and to analyze their correlation with esophageal acid exposure time (AET) on pH-metry. METHODS: Thirty-one gastro-oesophageal reflux disease (GERD) patients and 20 control subjects underwent 24-hour pH-metry and HRM using a 3D-HRM catheter...
April 11, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29643293/-a-case-of-non-cardiac-chest-pain-caused-by-esophageal-motility-disorder-observed-on-esophageal-high-resolution-manometry
#7
Kazumasa Muta, Eikichi Ihara, Yusuke Kitagawa, Shohei Hamada, Keita Fukaura, Tsutomu Iwasa, Akira Aso, Haruei Ogino, Kazuhiko Nakamura, Yoshihiro Ogawa
A 20-year-old man was referred to our hospital with dysphagia and chest pain. Heart disease was denied. No abnormality was observed in upper esophagogastroduodenoscopy and fluoroscopy;furthermore, no gastric acid-related symptoms were observed on combined esophageal multichannel intraluminal impedance and pH monitoring. Esophageal high-resolution manometry (HRM) performed by liquid swallow revealed normal peristalsis;however, HRM performed while the patient was taking solid meals showed abnormal contraction, and the patient simultaneously complained of chest pain...
2018: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/29622812/advances-in-the-management-of-oesophageal-motility-disorders-in-the-era-of-high-resolution-manometry-a-focus-on-achalasia-syndromes
#8
Peter J Kahrilas, Albert J Bredenoord, Mark Fox, C Prakash Gyawali, Sabine Roman, André J P M Smout, John E Pandolfino
This corrects the article DOI: 10.1038/nrgastro.2017.132.
April 6, 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29619102/dynamic-slow-motion-video-endoscopy-as-an-adjunct-to-impedance-audiometry-in-the-assessment-of-eustachian-tube-function
#9
Sanoop E Sanu, Shilpa Divakaran, Sabarinath Vijayakumar, Sunil Kumar Saxena, Arun Alexander, Suryanarayanan Gopalakrishnan
Introduction  Eustachian tube (ET) dysfunction plays an important role not only in the pathophysiology of various middle ear disorders, but also in predicting the outcome of the treatment. As there is no single test that assesses both the anatomic and physiological functions of the ET, a combination of tympanometry and dynamic slow motion video endoscopy may improve the sensitivity of ET function assessment. Objective  To find out if there is any correlation between dynamic slow motion nasal video endoscopy and impedance audiometry in assessing ET function in patients with middle ear diseases...
April 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29618340/3d-high-resolution-anorectal-manometry-in-patients-with-perianal-fistulas-comparison-with-3d-anal-ultrasound
#10
Richelle J F Felt-Bersma, Maarten S Vlietstra, Paul F Vollebregt, Ingrid J M Han-Geurts, Vera Rempe-Sorm, Grietje J H Vander Mijnsbrugge, Charlotte B H Molenaar
BACKGROUND: Perianal fistula surgery can damage the anal sphincters which may cause faecal incontinence. By measuring regional pressures, 3D-HRAM potentially provides better guidance for surgical strategy in patients with perianal fistulas. The aim was to measure regional anal pressures with 3D-HRAM and to compare these with 3D-EUS findings in patients with perianal fistulas. METHODS: Consecutive patients with active perianal fistulas who underwent both 3D-EUS and 3D-HRAM at a clinic specialised in proctology were included...
April 4, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29617746/thoracoabdominal-pressure-gradient-and-gastroesophageal-reflux-insights-from-lung-transplant-candidates
#11
T Masuda, S K Mittal, B Kovacs, M Smith, R Walia, J Huang, R M Bremner
Advanced lung disease is associated with gastroesophageal reflux disease (GERD). The thoracoabdominal pressure gradient (TAPG) facilitates gastroesophageal reflux, but the effects of TAPG on gastroesophageal reflux in patients with pulmonary disease have not been well defined. Patients diagnosed with end-stage lung disease are expected to have the most extreme derangement in respiratory mechanics. The aim of this study is to explore the relationship between TAPG and reflux in lung transplant (LTx) candidates...
March 31, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29608597/a-clinical-study-of-peroral-endoscopic-myotomy-reveals-that-impaired-lower-esophageal-sphincter-relaxation-in-achalasia-is-not-only-defined-by-high-resolution-manometry
#12
Hiroki Sato, Kazuya Takahashi, Ken-Ichi Mizuno, Satoru Hashimoto, Junji Yokoyama, Shuji Terai
BACKGROUND AND AIM: Achalasia is an esophageal motility disorder characterized by impaired lower esophageal sphincter (LES) relaxation. On high-resolution manometry (HRM), impaired LES relaxation is defined by elevated integrated relaxation pressure (IRP). However, a new category of achalasia within the normal IRP range has been suggested. METHODS: HRM was performed using a Starlet device and an IRP threshold of 26 mmHg. Peroral endoscopic myotomy (POEM) was performed for cases of achalasia diagnosed using established methods...
2018: PloS One
https://www.readbyqxmd.com/read/29605979/acotiamide-has-no-effects-on-esophageal-motor-activity-or-esophagogastric-junction-compliance
#13
Hironobu Mikami, Norihisa Ishimura, Mayumi Okada, Daisuke Izumi, Eiko Okimoto, Shunji Ishihara, Yoshikazu Kinoshita
Background/Aims: The novel prokinetic drug acotiamide is used for treatment of functional dyspepsia. It is still unclear how acotiamide has effects on esophageal motor function. Esophageal peristalsis and esophagogastric junction (EGJ) compliance has an important role for prevention of esophageal mucosal damage caused by gastroesophageal reflux, however, few studies have analyzed the effects of acotiamide on those former activities and none have investigated its effects on EGJ compliance...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29605977/esophageal-motor-disorders-are-a-strong-and-independant-associated-factor-of-barrett-s-esophagus
#14
Camille Bazin, Alban Benezech, Marine Alessandrini, Jean-Charles Grimaud, Veronique Vitton
Background/Aims: Esophageal motor disorder (EMD) has been shown to be associated with gastroesophageal reflux disease (GERD). However, the association of EMD with a Barrett's esophagus (BE) is controversial. Our objective was to evaluate whether the presence of EMD was an independent factor associated with BE. Methods: A retrospective case-control study was conducted in GERD patients who all had oeso-gastroduodenal endoscopy and high-resolution esophageal manometry...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29605727/abnormal-high-resolution-manometry-findings-and-outcomes-after-paraesophageal-hernia-repair
#15
Andrea Wirsching, Qing Zhang, Susan E McCormick, Michal Hubka, Donald E Low
BACKGROUND: Abnormal esophageal peristalsis diagnosed by high resolution manometry (HRM) is found frequently as part of the preoperative evaluation of paraesophageal hernia (PEH) patients. The clinical relevance of these findings is currently largely unknown. STUDY DESIGN: From 2013 to 2016, 212 patients undergoing PEH repair were prospectively recorded in an IRB approved database. Preoperative HRM was available for reanalysis according to the latest Chicago Classification (v...
March 29, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29605413/distal-esophageal-spasm-a-review
#16
REVIEW
Mohamed Khalaf, Sejal Chowdhary, Puja Sukhwani Elias, Donald Castell
Distal esophageal spasm is a rare motility disorder presenting principally with non-obstructive dysphagia and non-cardiac chest pain. In symptomatic patients, the manometric diagnosis is made when > 10% of the wet swallows have simultaneous and/or premature contractions intermixed with normal peristalsis. We characterize manometry and barium as complimentary diagnostic approaches, and given the intermittent nature of the disorder, one should be always aware that IT IS ALMOST IMPOSSIBLE TO RULE OUT SPASM...
March 29, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29603510/esophageal-provocation-tests-are-they-useful-to-improve-diagnostic-yield-of-high-resolution-manometry
#17
REVIEW
D A Carlson, S Roman
High resolution manometry (HRM) is the gold standard to diagnose esophageal motility disorders but has some limitations. The inclusion of provocative tests might enhance the diagnostic yield of HRM. These tests are easy to perform and to add to the regular manometry protocol. Multiple rapid swallows (MRS; 5 2-mL swallows) is useful to assess the contractile reserve and deglutitive inhibition. The optimal number of MRS to perform might be 3 as suggested by Mauro et al. in this issue of Neurogastroenterology & Motility...
April 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29602998/clinical-feasibility-of-a-new-full-thickness-endoscopic-plication-device-gerdx%C3%A2-for-patients-with-gerd-results-of-a-prospective-trial
#18
Michael Weitzendorfer, Georg O Spaun, Stavros A Antoniou, Kai Witzel, Klaus Emmanuel, Oliver O Koch
BACKGROUND: Previous studies suggest clinical effectiveness of endoscopic full-thickness plication in selected patients with gastroesophageal reflux disease (GERD). The aim of this study was to assess the clinical safety and efficiency of the GERDx™ device by evaluating clinical parameters, reflux symptom scores, and quality of life (QoL). METHODS: Prospective one-arm trial evaluating the outcome of forty patients with GERD subjected to endoscopic plication with the GERDx™ device...
March 30, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29601320/esophageal-pressure-monitoring-why-when-and-how
#19
Takeshi Yoshida, Laurent Brochard
PURPOSE OF REVIEW: Esophageal manometry has shown its usefulness to estimate transpulmonary pressure, that is lung stress, and the intensity of spontaneous effort in patients with acute respiratory distress syndrome. However, clinical uptake of esophageal manometry in ICU is still low. Thus, the purpose of review is to describe technical tips to adequately measure esophageal pressure at the bedside, and then update the most important clinical applications of esophageal manometry in ICU...
March 29, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29600403/effect-of-subsequent-vaginal-delivery-on-bowel-symptoms-and-anorectal-function-in-women-who-sustained-a-previous-obstetric-anal-sphincter-injury
#20
Polly A Jordan, Madhu Naidu, Ranee Thakar, Abdul H Sultan
INTRODUCTION AND HYPOTHESIS: Our primary objective was to prospectively evaluate anorectal symptoms, anal manometry and endoanal ultrasound (EAUS) in women who followed the recommended mode of subsequent delivery following index obstetric anal sphincter injuries (OASIs) using our unit's standardised protocol. Our secondary objectives were to evaluate the role of internal anal sphincter defects and also to compare outcomes in a subgroup of symptomatic women with normal anorectal physiology...
March 29, 2018: International Urogynecology Journal
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