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https://www.readbyqxmd.com/read/29040492/foreign-body-impaction-in-the-esophagus-are-there-underlying-motor-disorders
#1
S Mazzadi, G B Salis, A García, H Iannicillo, V Fucile, J C Chiocca
Results: Compared with the control group, the impacted subjects presented marked reduction in amplitude and duration of esophageal contraction in the proximal esophagus. Conclusions: These motor disorders could be responsible for the foreign body impaction in the esophagus. However, we believe this patient group should be further studied by 24-hour esophageal manometry to reach a more accurate diagnosis by studying each patient's entire circadian cycle.
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29036585/ambulatory-ph-impedance-pressure-monitoring-as-a-diagnostic-tool-for-the-reflux-cough-syndrome
#2
T V K Herregods, A Pauwels, J Jafari, D Sifrim, A J P M Smout, A J Bredenoord, J Tack
Gastroesophageal reflux is considered to be a significant contributing factor to chronic unexplained cough. Patients are often presumed to have reflux-induced cough and are exposed to high-dose and long-term empirical therapy with proton pump inhibitors (PPIs) despite the limited treatment efficacy in this population. We aimed to assess the diagnostic value of 24-hour ambulatory pH-impedance-pressure monitoring for the diagnosis of reflux-induced chronic cough. In this multicenter study, we evaluated 192 patients with chronic cough using 24-hour pH-impedance-pressure monitoring off PPIs...
September 27, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29027725/severity-of-ineffective-esophageal-motility-is-associated-with-utilization-of-skeletal-muscle-relaxant-medications
#3
V Rangan, N S George, F Khan, Z Geng, S Gabbard, A Kichler, H Gittleman, R Fass
BACKGROUND: Ineffective esophageal motility (IEM) is the most common finding on high-resolution esophageal manometry (HREM). The underlying mechanisms for IEM remain to be fully elucidated. The aim of this study was to determine if utilization of skeletal muscle relaxants is associated with IEM, and with more severe subtypes of the disorder. METHODS: Patients with diagnosis of IEM were gender and age matched to patients with normal HREM. Demographic information, symptoms, endoscopic findings, medication usage and medical comorbidities were recorded...
October 13, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29024314/clinicomanometric-factors-associated-with-clinically-relevant-esophagogastric-junction-outflow-obstruction-from-the-sandhill-high-resolution-manometry-system
#4
B G Song, Y W Min, H Lee, B-H Min, J H Lee, P-L Rhee, J J Kim
BACKGROUND: Integrated relaxation pressure (IRP) is a key metric for diagnosing esophagogastric junction outflow obstruction (EGJOO). However, its normal value might be different according to the manufacturer of high-resolution manometry (HRM). This study aimed to investigate optimal value of IRP for diagnosing EGJOO in Sandhill HRM and to find clinicomanometric variables to segregate clinically relevant EGJOO. METHODS: We analyzed 262 consecutive subjects who underwent HRM between June 2011 and December 2016 showing elevated median IRP (> 15 mm Hg) but did not satisfy criteria for achalasia...
October 10, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29019566/preoperative-manometry-for-the-selection-of-obese-people-candidate-to-sleeve-gastrectomy
#5
Antonio Carlos Valezi, Fernando Augusto Herbella, Jorge Mali-Junior, Mariano de Almeida Menezes, Mário Liberatti, Rafael Onuki Sato
BACKGROUND: Sleeve gastrectomy may alter esophageal motility and lower esophageal sphincter pressure. AIM: To detect manometric changings in the esophagus and lower esophageal sphincter before and after sleeve gastrectomy in order to select patients who could develop postoperative esophageal motilitity disorders and lower esophageal sphincter pressure modifications. METHODS: Seventy-three patients were selected. All were submitted to manometry before the operation and one year after...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/29019565/sleeve-gastrectomy-and-fundoplication-as-a-single-procedure-in-patients-with-obesity-and-gastroesophageal-reflux
#6
Juan Pablo Lasnibat, Italo Braghetto, Luis Gutierrez, Felipe Sanchez
BACKGROUND: Bariatric surgery in Chile has seen an exponential increase in recent years, especially in sleeve gastrectomy. Its use is currently discussed in patients suffering from gastroesophageal reflux disease. Different options have been considered for the management of these patients but up to now laparoscopic Roux-en-Y gastric bypass seems to be the best option. Sleeve gastrectomy plus concomitant fundoplication or hiatal hernia repair also has been suggested in patients having reflux or small hiatal hernia...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/29018480/comparison-of-esophageal-function-tests-in-chinese-patients-with-functional-heartburn-and-reflux-hypersensitivity
#7
Feng Gao, Yan Gao, Xue Chen, Jie Qian, Jie Zhang
OBJECTIVE: To investigate the differences in the results of esophageal function tests for functional heartburn (FH) and reflux hypersensitivity (RH). METHODS: Patients with FH and RH and healthy volunteers (HVs) from the Department of Gastroenterology, Beijing Anzhen Hospital and Beijing Chao-Yang hospital, who underwent high-resolution manometry and impedance (HRIM), and 24-hour multichannel intraluminal impedance and pH recording (MII/pH) between 2014 and 2016, were enrolled in this study...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28993985/gastroesophageal-reflux-after-sleeve-gastrectomy-a-prospective-mechanistic-study
#8
Muriel Coupaye, Caroline Gorbatchef, Daniela Calabrese, Ouidad Sami, Simon Msika, Benoit Coffin, Séverine Ledoux
BACKGROUND: Evolution of gastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) is controversial. Some authors report worsening or improvement of preoperative GERD, others the occurrence of de novo GERD between 5 and 69%. AIMS: The aims of this study are to evaluate the evolution of GERD after SG by ambulatory 24-h pH monitoring (APM) and to determine pre- and postoperative clinical and manometric factors associated with its evolution. METHODS: Between 2013 and 2015, 47 patients operated in our center performed APM before and 1 year (14...
October 9, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28992673/reflux-hypersensitivity-a-new-functional-esophageal-disorder
#9
REVIEW
Takahisa Yamasaki, Ronnie Fass
Reflux hypersensitivity, recently introduced by Rome IV as a new functional esophageal disorder, is currently considered as the presence of typical heartburn symptoms in patients with normal upper endoscopy and esophageal biopsies, normal esophageal pH test and with evidence of a close correlation between patients' heartburn and reflux events. Reflux hypersensitivity is very common and together with functional heartburn accounts for more than 90% of the heartburn patients who failed treatment with proton pump inhibitor twice daily...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28989555/noninvasive-evaluation-of-varying-pulse-pressures-in-vivo-using-brachial-sphymomanometry-applanation-tonometry-and-pulse-wave-ultrasound-manometry
#10
Ronny X Li, Ada Ip, Elena Sanz-Miralles, Elisa E Konofagou
The routine assessment and monitoring of hypertension may benefit from the evaluation of arterial pulse pressure (PP) at more central locations (e.g. the aorta) rather solely at the brachial artery. Pulse Wave Ultrasound Manometry (PWUM) was previously developed by our group to provide direct, noninvasive aortic PP measurements using ultrasound elasticity imaging. Using PWUM, radial applanation tonometry, and brachial sphygmomanometry, this study investigated the feasibility of noninvasively obtaining direct PP measurements at multiple arterial locations in normotensive, pre-hypertensive, and hypertensive human subjects...
June 2017: Artery Research
https://www.readbyqxmd.com/read/28988414/upper-esophageal-sphincter-augmentation-reduces-pharyngeal-reflux-in-nasogastric-tube-fed-patients
#11
Hongmei Jiao, Ling Mei, Chenyang Liang, Yun Dai, Zhifang Fu, Lihong Wu, Patrick Sanvanson, Reza Shaker
OBJECTIVES/HYPOTHESIS: Aspiration of gastric refluxate is one of the most commonly observed complications among long-term nasogastric tube (NGT) fed patients. The upper esophageal sphincter (UES) pressure barrier is the main defense mechanism against pharyngeal reflux of gastric contents. Our objective was to investigate the efficacy and safety of the UES assist device (UES-AD) in preventing gastric reflux through the UES in long-term NGT-fed patients. STUDY DESIGN: Self-Controlled Case series...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28987504/aga-institute-high-value-care-statement-is-high-resolution-manometry-always-needed-for-the-diagnosis-of-achalasia
#12
Dustin A Carlson, C Prakash Gyawali
No abstract text is available yet for this article.
October 5, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28984521/idiopathic-intracranial-hypertension-120-day-clinical-radiological-and-manometric-outcomes-after-stent-insertion-into-the-dural-venous-sinus
#13
Hasan Asif, Claudia L Craven, Almas H Siddiqui, Syed N Shah, Samir A Matloob, Lewis Thorne, Fergus Robertson, Laurence D Watkins, Ahmed K Toma
OBJECTIVE Idiopathic intracranial hypertension (IIH) is commonly associated with venous sinus stenosis. In recent years, transvenous dural venous sinus stent (DVSS) insertion has emerged as a potential therapy for resistant cases. However, there remains considerable uncertainty over the safety and efficacy of this procedure, in particular the incidence of intraprocedural and delayed complications and in the longevity of sinus patency, pressure gradient obliteration, and therapeutic clinical outcome. The aim of this study was to determine clinical, radiological, and manometric outcomes at 3-4 months after DVSS in this treated IIH cohort...
October 6, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28976308/a-procedure-for-the-automatic-analysis-of-high-resolution-manometry-data-to-support-the-clinical-diagnosis-of-esophageal-motility-disorders
#14
Alessandro Frigo, Mario Costantini, Chiara Giulia Fontanella, Stefano Merigliano, Emanuele Luigi Carniel
OBJECTIVE: Degenerative phenomena may affect esophageal motility as a relevant social-health problem. The diagnosis of such disorders is usually performed by the analysis of data from high resolution manometry (HRM). Inter- and intra-observer variability frequently affects the diagnosis, with potential interpretative and thus therapeutic errors, with unnecessary or worse treatments. This may be avoided with automatic procedures that minimize human intervention in data processing. METHODS: In order to support the traditional diagnostic process, an automatic procedure was defined considering a specific physio-mechanical model that is able to objectively interpret data from HRM...
October 2, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28975391/reduced-upper-obstructions-in-n3-and-increased-lower-obstructions-in-rem-sleep-stage-detected-with-manometry
#15
Markus Wirth, Juliane Schramm, Maximilian Bautz, Benedikt Hofauer, Günther Edenharter, Armin Ott, Clemens Heiser
In obstructive sleep apnea (OSA), airway obstruction occurs at different anatomic levels. The frequency and location of obstructions play a crucial role in the planning of surgical treatment. The aim of this study was to evaluate the pharyngeal obstruction levels in different sleep stages with manometry in OSA patients. In addition, the manometry results were compared with drug-induced sleep endoscopy (DISE). Forty-one patients with OSA received manometry measurements during one night of sleep. All patients were simultaneously evaluated with polysomnography...
October 3, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28953511/therapeutic-outcome-of-achalasia-based-on-high-resolution-manometry-a-korean-multicenter-study
#16
Hyuk Lee, Hyunsoo Chung, Tae Hee Lee, Kyoung Sup Hong, Young Hoon Youn, Jung Ho Park, Hyung Seok Park, Hyojin Park
BACKGROUND: Because achalasia subtype is associated with therapeutic response, it is possible that regional differences in subtype distribution could lead to differences in therapeutic outcomes. STUDY QUESTION: We aimed to evaluate and compare high-resolution manometry (HRM) profiles among the different subtypes of achalasia and to elucidate predictive factors associated with treatment outcomes. STUDY DESIGN: Patients who were diagnosed with achalasia using HRM at 4 Korean university hospitals were retrospectively identified and analyzed...
September 11, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28951582/expert-consensus-document-advances-in-the-physiological-assessment-and-diagnosis-of-gerd
#17
REVIEW
Edoardo Savarino, Albert J Bredenoord, Mark Fox, John E Pandolfino, Sabine Roman, C Prakash Gyawali
GERD is a common condition worldwide. Key mechanisms of disease include abnormal oesophagogastric junction structure and function, and impaired oesophageal clearance. A therapeutic trial of acid-suppressive PPI therapy is often the initial management, with endoscopy performed in the setting of alarm symptoms and to exclude other conditions. If symptoms persist and endoscopy does not reveal evidence of GERD, oesophageal function tests are performed, including oesophageal manometry and ambulatory reflux monitoring...
September 27, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28951579/expert-consensus-document-advances-in-the-management-of-oesophageal-motility-disorders-in-the-era-of-high-resolution-manometry-a-focus-on-achalasia-syndromes
#18
REVIEW
Peter J Kahrilas, Albert J Bredenoord, Mark Fox, C Prakash Gyawali, Sabine Roman, André J P M Smout, John E Pandolfino
High-resolution manometry (HRM) and new analysis algorithms, summarized in the Chicago Classification, have led to a restructured classification of oesophageal motility disorders. This advance has led to increased detection of clinically relevant disorders, in particular achalasia. It has become apparent that the cardinal feature of achalasia - impaired lower oesophageal sphincter (LES) relaxation - can occur in several disease phenotypes: without peristalsis (type I), with pan-oesophageal pressurization (type II), with premature (spastic) distal oesophageal contractions (type III), or with preserved peristalsis (outlet obstruction)...
September 27, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28950040/fecal-incontinence-in-patients-with-spina-bifida-the-target-is-the-rectum
#19
Charlène Brochard, Alain Ropert, Benoît Peyronnet, Hélène Ménard, Andréa Manunta, Michel Neunlist, Guillaume Bouguen, Laurent Siproudhis
AIMS: The prevalence rate of severe fecal incontinence (FI) in adults with spina bifida (SB) is high. The physiological basis of FI in SB has not been clearly established, which contributes to inadequate care. The aim was to better characterize a large cohort of adults with special consideration of anorectal physiology. METHODS: A multidisciplinary team from a French referral centre for SB prospectively collected data on patients who had an anorectal manometry. Factors associated with severe FI (Cleveland clinical incontinence score ≥ 9) were assessed in a multivariate analysis model...
September 26, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28948708/variation-in-high-resolution-esophageal-manometry-methodology-in-clinical-practice-results-from-an-international-survey
#20
R Sweis, H Heinrich, M Fox
BACKGROUND: Advances in clinical measurement of esophageal motility and function have improved the assessment of swallowing disorders and reflux symptoms. Variation in data acquisition, analysis, and reporting exists and impacts on diagnosis and management. AIMS AND METHODS: This study examined variation in esophageal manometry methodology between institutions to establish the status in current practice. A structured survey was distributed through international NGM societies using an Internet-based platform...
September 25, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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