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https://www.readbyqxmd.com/read/30287424/acute-kidney-injury-among-hospitalized-children-in-china
#1
Xin Xu, Sheng Nie, Aihua Zhang, Jianhua Mao, Hai-Peng Liu, Huimin Xia, Hong Xu, Zhangsuo Liu, Shipin Feng, Wei Zhou, Xuemei Liu, Yonghong Yang, Yuhong Tao, Yunlin Feng, Chunbo Chen, Mo Wang, Yan Zha, Jian-Hua Feng, Qingchu Li, Shuwang Ge, Jianghua Chen, Yongcheng He, Siyuan Teng, Chuanming Hao, Bi-Cheng Liu, Ying Tang, Wenjuan He, Pinghong He, Fan Fan Hou
BACKGROUND AND OBJECTIVES: High-quality epidemiologic data on AKI in children are particularly lacking in developing countries. This study aimed to assess the epidemiology and clinical correlates of AKI among hospitalized children in China. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a multicenter study, in a cohort of hospitalized children aged 1 month to 18 years, from 25 general and children's hospitals in China during 2013-2015. We obtained patient-level data from the electronic hospitalization information system and laboratory databases of all children who had at least two serum creatinine tests within any 7-day window during their first 30 days of hospitalization...
October 4, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/30248465/outcomes-in-patients-with-fungal-endocarditis-a-multicenter-observational-cohort-study
#2
Rinaldo Focaccia Siciliano, Danielle Menosi Gualandro, Odeli Nicole Encinas Sejas, Bruno Giuliano Ignoto, Bruno Caramelli, Alfredo Jose Mansur, Roney Orismar Sampaio, Ligia Camera Pierrotti, Giovanna Barbosa, Wilma Golebiovski, Clara Weksler Cristiane Lamas, Natália Rodrigues Querido Fortes, Claudio Querido Fortes, Flavio Tarasoutchi, Tania Mara Varejão Strabelli
PURPOSE: To compare the clinical and epidemiological features, treatment and outcome of patients with isolated right-sided and left-sided fungal endocarditis and to determine the risk factors for in-hospital mortality in patients with Candida sp. endocarditis. METHODS: A retrospective review of all consecutive cases of fungal endocarditis from five hospitals was performed. We compared clinical features between patients with isolated right-sided and left-sided endocarditis...
September 21, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/30236796/metabolic-syndrome-and-hip-fracture-epidemiology-and-perioperative-outcomes
#3
Kyle H Cichos, Jessica L Churchill, Sierra G Phillips, Shawna L Watson, Gerald McGwin, Elie S Ghanem, Brent A Ponce
INTRODUCTION: Hip fractures and metabolic syndrome (MetS) are becoming major global healthcare burdens as populations age. This study sought to determine the impact of MetS in hip fracture patients on perioperative outcomes following operative fixation or arthroplasty. METHODS: Data from the 2004-2014 Nationwide Inpatient Sample was used to select 3,348,207 discharges with hip fracture. MetS patients were identified by having at least 3 of 4 component comorbidities: hypertension, dyslipidemia, obesity, and diabetes...
September 8, 2018: Injury
https://www.readbyqxmd.com/read/30234899/cardiac-sarcoidosis-and-ventricular-arrhythmias-a-rare-association-of-a-rare-disease-a-retrospective-cohort-study-from-the-national-inpatient-sample-and-current-evidence-for-management
#4
Amr Salama, Abdullah Abdullah, Abdul Wahab, George Eigbire, Ryan Hoefen, Richard Alweis
BACKGROUND: Sarcoidosis is an increasingly recognized multi-systemic condition. Cardiac sarcoidosis is associated with ventricular arrhythmias and higher mortality rates. Little epidemiological data is available regarding the disease and associated ventricular arrhythmias. METHODS: Data from the National Inpatient Sample (NIS) database 2012-2014, were reviewed. Discharges associated with sarcoidosis were identified as the target population using relevant ICD-9-CM codes...
September 20, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/30179138/churg-strauss-syndrome-presenting-as-acute-necrotizing-eosinophilic-myocarditis-concise-review-of-the-literature
#5
Muhammad Ali Chaudhry, Luanda Grazette, Andrew Yoon, Adrian Correa, Michael W Fong
Acute eosinophilic myocarditis (EM) is a rare form of heart failure that is characterized by myocardial eosinophilic infiltration usually in association with peripheral eosinophilia. The underlying cause is variable and can include allergic reactions, parasitic infection, idiopathic hypereosinophilic syndrome, malignancy, Loeffler's syndrome, Churg-Strauss syndrome (CSS), early giant cell myocarditis and malignancy. The course is potentially fatal, and early diagnosis and treatment with steroids is essential...
September 3, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/30140928/enrollment-of-older-patients-women-and-racial-and-ethnic-minorities-in-contemporary-heart-failure-clinical-trials-a-systematic-review
#6
Ayman Samman Tahhan, Muthiah Vaduganathan, Stephen J Greene, Gregg C Fonarow, Mona Fiuzat, Mariell Jessup, JoAnn Lindenfeld, Christopher M O'Connor, Javed Butler
Importance: Despite the importance of age, sex, and race/ethnicity representativeness in clinical trials, limited data exist regarding the enrollment trends of these groups in contemporary heart failure (HF) trials. Objective: To characterize the representation of older patients, women, and racial and ethnic minorities in HF trials. Evidence Review: We performed a systematic search of HF trials enrolling more than 400 participants published between January 2001 and December 2016 using PubMed/Medline and ClinicalTrials...
August 22, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/30138176/update-on-perioperative-acute-kidney-injury
#7
Alexander Zarbock, Jay L Koyner, Eric A J Hoste, John A Kellum
Acute kidney injury (AKI) in the perioperative period is a common complication and is associated with increased morbidity and mortality. A standard definition and staging system for AKI has been developed, incorporating a reduction of the urine output and/or an increase of serum creatinine. Novel biomarkers may detect kidney damage in the absence of a change in function and can also predict the development of AKI. Several specific considerations for AKI risk are important in surgical patients. The surgery, especially major and emergency procedures in critically ill patients, may cause AKI...
August 22, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/30061497/the-centrality-of-sepsis-a-review-on-incidence-mortality-and-cost-of-care
#8
REVIEW
Jihane Hajj, Natalie Blaine, Jola Salavaci, Douglas Jacoby
Sepsis is a serious and fatal medical condition that has overburdened the US healthcare system. The purpose of this paper is to provide a review of published literature on severe sepsis with a distinct focus on incidence, mortality, cost of hospital care, and postdischarge care. A review of the nature of postsepsis syndrome and its impact on septic patients is also included. The literature review was conducted utilizing the PubMed database, identifying 34 studies for inclusion. From the evaluation of these studies, it was determined that the incidence of sepsis continues to be on the rise according to three decades of epidemiological data...
July 30, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29957138/early-onset-prosthetic-valve-endocarditis-experience-at-a-cardiothoracic-surgical-hospital-2006-2016
#9
Rafael Quaresma Garrido, José Oscar Dos Reis Brito, Ralph Fernandes, Giovanna Ferraiuoli Barbosa, Marcelo Goulart Correia, Wilma Felix Golebiovski, Clara Weksler, Cristiane C Lamas
BACKGROUND: Early onset prosthetic valve endocarditis (EO-PVE) is an serious complication associated with heart valve replacement surgery. OBJECTIVES: To describe the epidemiologic, clinical, and laboratory profile of patients with EO-PVE in a cardiac surgical hospital. PATIENTS AND METHODS: A retrospective analysis of an endocarditis database, implemented prospectively, with a post hoc study driven by analysis of cases of adults with definite endocarditis occurring up to 12 months after heart valve surgery...
July 2018: Surgical Infections
https://www.readbyqxmd.com/read/29932968/time-trends-in-the-prevalence-of-cancer-and-non-cancer-diseases-among-older-u-s-adults-medicare-based-analysis
#10
Igor Akushevich, Julia Kravchenko, Arseniy P Yashkin, Anatoliy I Yashin
Longer lifespan is accompanied by a larger number of chronic diseases among older adults. Because of a growing proportion of older adults in the U.S., this brings the problem of age-related morbidity to the forefront as a major contributor to rising medical expenditures. We evaluated 15-year time trends (from 1998 to 2013) in the prevalence of 48 acute and chronic non-cancer diseases and cancers in older U.S. adults aged 65+ and estimated the annual percentage changes of these prevalence trends using SEER-Medicare and HRS-Medicare data...
September 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29923940/factors-associated-with-mechanical-ventilation-use-in-children-with-sickle-cell-disease-and-acute-chest-syndrome
#11
Takuto Takahashi, Yusuke Okubo, Maria A Pereda, Atsuhiko Handa, Scott Miller
OBJECTIVES: Acute chest syndrome is the leading cause of death in children with sickle cell disease and is generally due to respiratory failure. Epidemiologic factors for a need for mechanical ventilation in children with acute chest syndrome require further clarification. DESIGN: Retrospective observational study. SETTING: Nationally representative pediatric inpatient records in the United States by using the Kids' Inpatient Database for the years 2003, 2006, 2009, and 2012...
September 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29913923/national-guidelines-for-evaluating-pain-patients-legal-right-to-prioritised-health-care-at-multidisciplinary-pain-clinics-in-norway-implemented-2009
#12
Karen Walseth Hara, Petter Borchgrevink
Background All nations are posed with the challenge of deciding how to allocate limited health care resources. A Patients' Rights Law from 1999 gives patients in Norway with a serious health condition, for which there is efficacious and cost-effective treatment, a legal right to receive health care from the National Health Care system. Methods Recently national guidelines have been produced for implementing these legal rights within 32 fields of specialist health care. One of these fields deals with serious chronic pain conditions...
January 1, 2010: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29902694/challenges-of-evaluating-chronic-heart-failure-and-acute-heart-failure-events-in-research-studies-using-large-health-care-databases
#13
REVIEW
Miguel Cainzos-Achirica, Cristina Rebordosa, Emili Vela, Montse Cleries, Kunihiro Matsushita, Estel Plana, Elena Rivero-Ferrer, Cristina Enjuanes, Santiago Jimenez-Marrero, Luis Alberto Garcia-Rodriguez, Josep Comin-Colet, Susana Perez-Gutthann
Epidemiological studies on heart failure (HF) using large health care databases are becoming increasingly frequent, as they represent an invaluable opportunity to characterize the importance and risk factors of HF from a population perspective. Nevertheless, because of its complex diagnosis and natural history, the heterogeneous use of the relevant terminology in routine clinical practice, and the limitations of some disease coding systems, HF can be a challenging condition to assess using large health care databases as the main source of information...
August 2018: American Heart Journal
https://www.readbyqxmd.com/read/29863638/characteristics-risk-factors-and-outcomes-of-extracorporeal-membrane-oxygenation-use-in-pediatric-cardiac-icus-a-report-from-the-pediatric-cardiac-critical-care-consortium-registry
#14
Marissa A Brunetti, J William Gaynor, Lauren B Retzloff, Jessica L Lehrich, Mousumi Banerjee, Venugopal Amula, David Bailly, Darren Klugman, Josh Koch, Javier Lasa, Sara K Pasquali, Michael Gaies
OBJECTIVES: Cardiopulmonary failure in children with cardiac disease differs from the general pediatric critical care population, yet the epidemiology of extracorporeal membrane oxygenation support in cardiac ICUs has not been described. We aimed to characterize extracorporeal membrane oxygenation utilization and outcomes across surgical and medical patients in pediatric cardiac ICUs. DESIGN: Retrospective analysis of the Pediatric Cardiac Critical Care Consortium registry to describe extracorporeal membrane oxygenation frequency and outcomes...
June 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29803531/vertigo-and-dizziness-understanding-and-managing-fall-risk
#15
REVIEW
Jennifer C Alyono
Vertigo and dizziness are common conditions among older adults. They are closely associated with fall risk and portend major implications for geriatric injury and disability. Management can be particularly challenging, because symptoms are often nonspecific and may reflect multiple etiologies. Chronic dizziness can reflect dysfunction in the vestibular, somatosensory, or visual systems or in their central integration. Systemic processes, such as postural hypotension, arrhythmias, heart failure, medication use, and lower extremity weakness or frailty, also contribute...
August 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29753371/cardiovascular-events-in-alcoholic-syndrome-with-alcohol-withdrawal-history-results-from-the-national-inpatient-sample
#16
Parasuram Krishnamoorthy, Aditi Kalla, Vincent M Figueredo
BACKGROUND: Epidemiologic studies suggest reduced cardiovascular disease (CVD) events with moderate alcohol consumption. However, heavy and binge drinking may be associated with higher CVD risk. Utilizing the Nationwide Inpatient Sample, we studied the association between a troublesome alcohol history (TAH), defined as those with diagnoses of both chronic alcohol syndrome and acute withdrawal history and CVD events. METHODS: Patients >18 years with diagnoses of both chronic alcohol syndrome and acute withdrawal using the International Classification of Diseases-Ninth Edition-Clinical Modification (ICD-9-CM) codes 303...
May 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29731500/sleep-disordered-breathing-a-real-therapeutic-target-for-hypertension-pulmonary-hypertension-ischemic-heart-disease-and-chronic-heart-failure
#17
REVIEW
Takaaki Nakamoto
Sleep-disordered breathing (SDB) is a risk factor for cardiovascular disease including acute coronary syndrome and acute myocardial infarction, and treating SDB prevents their development and recurrence and improves a patient's prognosis. Therefore, SDB is considered a therapeutic target for cardiovascular disease. In 2010, the Japanese Circulation Society published guidelines for the diagnosis and treatment of SDB in patients with cardiovascular disease. However, therapeutic intervention for patients with SDB was recently reported not to suppress the development or deterioration of cardiovascular disease in three middle- to large-sized randomized clinical trials: the SERVE-HF trial, which examined the effects of adaptive servo-ventilation (ASV) on patients with chronic heart failure (CHF) and central sleep apnea; the CAT-HF trial, which examined the effects of ASV therapy on patients with CHF after acute deterioration; and the SAVE study, which examined the secondary preventive effect of continuous positive airway pressure (CPAP) on patients with ischemic heart disease who had mild to moderate obstructive sleep apnea...
2018: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/29663995/-risk-factors-of-atrial-fibrillation-in-critical-ill-patients
#18
Jianyu Fu, Hongying Bi, Yunsong Xia, Hui Fang, Xu Liu, Yan Tang, Difen Wang
OBJECTIVE: To observe the clinical features of atrial fibrillation (AF) patients, and to explore the correlation between the routine detection index and the new-onset AF and to find out risk factors for new AF in critically ill patients. METHODS: A prospective observational study was conducted. The patients with AF admitted to intensive care unit (ICU) of the Affiliated Hospital of Guizhou Medical University from March 2016 to June 2017 were enrolled. The patients were divided into new-onset AF group and past-existed AF group according to their past history of AF (including persistent AF, paroxysmal AF or permanent AF)...
April 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29650544/evaluation-and-management-of-right-sided-heart-failure-a-scientific-statement-from-the-american-heart-association
#19
REVIEW
Marvin A Konstam, Michael S Kiernan, Daniel Bernstein, Biykem Bozkurt, Miriam Jacob, Navin K Kapur, Robb D Kociol, Eldrin F Lewis, Mandeep R Mehra, Francis D Pagani, Amish N Raval, Carey Ward
BACKGROUND AND PURPOSE: The diverse causes of right-sided heart failure (RHF) include, among others, primary cardiomyopathies with right ventricular (RV) involvement, RV ischemia and infarction, volume loading caused by cardiac lesions associated with congenital heart disease and valvular pathologies, and pressure loading resulting from pulmonic stenosis or pulmonary hypertension from a variety of causes, including left-sided heart disease. Progressive RV dysfunction in these disease states is associated with increased morbidity and mortality...
May 15, 2018: Circulation
https://www.readbyqxmd.com/read/29643111/cardiovascular-and-cerebrovascular-emergency-department-visits-associated-with-wildfire-smoke-exposure-in-california-in-2015
#20
Zachary S Wettstein, Sumi Hoshiko, Jahan Fahimi, Robert J Harrison, Wayne E Cascio, Ana G Rappold
BACKGROUND: Wildfire smoke is known to exacerbate respiratory conditions; however, evidence for cardiovascular and cerebrovascular events has been inconsistent, despite biological plausibility. METHODS AND RESULTS: A population-based epidemiologic analysis was conducted for daily cardiovascular and cerebrovascular emergency department (ED) visits and wildfire smoke exposure in 2015 among adults in 8 California air basins. A quasi-Poisson regression model was used for zip code-level counts of ED visits, adjusting for heat index, day of week, seasonality, and population...
April 11, 2018: Journal of the American Heart Association
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