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Coeliac disease

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https://www.readbyqxmd.com/read/27918167/-coeliac-disease-as-a-possible-cause-of-some-gynecological-and-obstetric-abnormalities
#1
K Fiolková, K Biringer, M Hrtánková, R Fiolka, J Danko
OBJECTIVE: To bring a review of available literature sources on the prevalence of coeliac disease and its possible impact on gynecological and obstetric disorders. DESIGN: Review article. SETTING: Gynecology and Obstetrics Clinic, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia. METHODS: Analysis of literary sources. CONCLUSION: Coeliac disease is an autoimmune enteropathy caused by abnormal immune system response to gluten...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27913607/autoimmune-comorbidities-in-hashimoto-s-thyroiditis-different-patterns-of-association-in-adulthood-and-childhood-adolescence
#2
R M Ruggeri, F Trimarchi, G Giuffrida, R Certo, E Cama, A Campennì, A Alibrandi, F De Luca, M Wasniewska
OBJECTIVE: Hashimoto's thyroiditis (HT), the most common autoimmune thyroid disease at any age, is often associated with other autoimmune diseases. The present study was aimed to describe the type and frequency of non-thyroidal autoimmune diseases (NTADs) in HT patients and to delineate the clinical pattern of diseases clustering in pediatric/adolescent and adult age. DESIGN: Cross-sectional study. METHODS: 1053 newly diagnosed HT patients (500 adults (467 F, mean age 40...
February 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27910801/epidemiologic-and-therapeutic-aspects-of-refractory-coeliac-disease-a-systematic-review
#3
Sara Anna Rowinski, Erik Christensen
INTRODUCTION: Refractory coeliac disease (RCD) is a rare and severe malabsorptive disease. The condition has two subtypes: RCDI and RCDII. Different treatments have been tested: and because RCD has a poor prognosis due to progress to enteropathy-associated T-cell lymphoma, the aim was to review the epidemiologic aspects and the therapeutic options for RCD. METHODS: A systematic literature search was performed in 18 databases, and 122 records were identified. Incidence, prevalence, treatment methods and their efficacy were evaluated...
December 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27900523/liver-test-abnormalities-predict-complicated-disease-behaviour-in-patients-with-newly-diagnosed-crohn-s-disease
#4
Jessika Barendregt, Myrthe de Jong, Jeoffrey J Haans, Bart van Hoek, James Hardwick, Roeland Veenendaal, Andrea van der Meulen, Nidhi Srivastava, Rogier Stuyt, Jeroen Maljaars
BACKGROUNDS: In coeliac disease, the prevalence of liver test abnormalities (LTAs) is higher in patients with more severe mucosal inflammation. In Crohn's disease, prognosis is related to the severity of mucosal inflammation. AIM: The aim of this study was to investigate whether the presence of LTA predicts the occurrence of complicated disease behaviour in newly diagnosed Crohn's disease. METHODS: A retrospective cohort study was performed in patients newly diagnosed with Crohn's disease between 2002 and 2011...
November 29, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27885681/dynamics-of-occurrence-of-refractory-coeliac-disease-and-associated-complications-over-25%C3%A2-years
#5
W Eigner, K Bashir, C Primas, L Kazemi-Shirazi, F Wrba, M Trauner, H Vogelsang
BACKGROUND: Refractory coeliac disease, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma are rare but prognostically important complications in coeliac disease. AIM: To analyse potential changes in occurrence of complicated coeliac disease over the last 25 years. METHODS: One thousand one hundred and thirty eight patients were included and evaluated based on their time of first presentation at the Medical University of Vienna, Austria...
November 25, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27852116/non-coeliac-gluten-wheat-sensitivity-advances-in-knowledge-and-relevant-questions
#6
Umberto Volta, Giacomo Caio, Tennekoon B Karunaratne, Armin Alaedini, Roberto De Giorgio
Non-coeliac gluten/wheat sensitivity (NCG/WS) is a syndrome characterized by intestinal and extra-intestinal symptoms occurring a few hours or days after the ingestion of gluten and wheat proteins in patients testing negative for coeliac disease and wheat allergy. Areas covered: The present review deals with recent scientific acquisitions of this gluten-related syndrome, including pathogenetic mechanisms, clinical picture, symptom score, biomarkers and double-blind placebo-controlled trial for diagnosis, and treatment...
November 23, 2016: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27849120/review-gut-microbiota-and-functional-diseases-of-the-gastrointestinal-tract
#7
Nicola Imperatore, Raffaella Tortora, Filomena Morisco, Nicola Caporaso
INTRODUCTION: Functional gastrointestinal disorders (FGIDs) are a common group of chronic gastrointestinal (GI) diseases defined by symptom-based diagnostic criteria, which consider chronic or recurrent symptoms of the GI tract in the absence of other organic or biochemical reasons. Recent evidences have been highlighted the role of gut microbiota in the pathophysiology of the FGIDs. EVIDENCE ACQUISITION: We focused our attention on critically analysis of the existing literature on the role of gut microbiota in FGIDs, by evaluating the differences of composition, functions and role of intestinal flora in FGIDs of the upper and lower gastrointestinal tract...
November 16, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27827438/changes-in-duodenal-tissue-associated-microbiota-following-hookworm-infection-and-consecutive-gluten-challenges-in-humans-with-coeliac-disease
#8
Paul Giacomin, Martha Zakrzewski, Timothy P Jenkins, Xiaopei Su, Rafid Al-Hallaf, John Croese, Stefan de Vries, Andrew Grant, Makedonka Mitreva, Alex Loukas, Lutz Krause, Cinzia Cantacessi
A reduced diversity of the gastrointestinal commensal microbiota is associated with the development of several inflammatory diseases. Recent reports in humans and animal models have demonstrated the beneficial therapeutic effects of infections by parasitic worms (helminths) in some inflammatory disorders, such as inflammatory bowel disease (IBD) and coeliac disease (CeD). Interestingly, these studies have described how helminths may alter the intestinal microbiota, potentially representing a mechanism by which they regulate inflammation...
November 9, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27821042/two-jenuno-jenunal-intussusceptions-in-a-patient-with-coeliac-disease
#9
K Moubax, F Mana, H Reynaert, D Urbain
We present a case of a 41-year-old woman with severe abdominal pain caused by two jejuno-jejunal intussusceptions. Further investigation showed coeliac disease as the underlying cause. The patient recovered rapidly on a gluten-free diet. So coeliac disease could be the underlying cause of idiopathic intussusception more often than previously thought and intussusception should be suspected in patients with known coeliac disease presenting with abdominal pain. (Acta gastro-enterol. belg., 2016, 79, 000-000).
July 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/27803799/approach-to-patients-with-refractory-coeliac-disease
#10
REVIEW
Ikram Nasr, Iman Nasr, Hannah Campling, Paul J Ciclitira
Refractory coeliac disease (RCD) is a recognised complication, albeit very rare, of coeliac disease (CD). This condition is described when individuals with CD continue to experience enteropathy and subsequent or ongoing malabsorption despite strict adherence to a diet devoid of gluten for at least 12 months and when all other causes mimicking this condition are excluded. Depending on the T-cell morphology and T-cell receptor (TCR) clonality at the β/γ loci, RCD can be subdivided into type 1 (normal intra-epithelial lymphocyte morphology, polyclonal TCR population) and type 2 (aberrant IELs with clonal TCR)...
2016: F1000Research
https://www.readbyqxmd.com/read/27799282/disease-activity-indices-in-coeliac-disease-systematic-review-and-recommendations-for-clinical-trials
#11
Pieter Hindryckx, Barrett G Levesque, Tom Holvoet, Serina Durand, Ceen-Ming Tang, Claire Parker, Reena Khanna, Lisa M Shackelton, Geert D'Haens, William J Sandborn, Brian G Feagan, Benjamin Lebwohl, Daniel A Leffler, Vipul Jairath
OBJECTIVE: Although several pharmacological agents have emerged as potential adjunctive therapies to a gluten-free diet for coeliac disease, there is currently no widely accepted measure of disease activity used in clinical trials. We conducted a systematic review of coeliac disease activity indices to evaluate their operating properties and potential as outcome measures in registration trials. DESIGN: MEDLINE, EMBASE and the Cochrane central library were searched from 1966 to 2015 for eligible studies in adult and/or paediatric patients with coeliac disease that included coeliac disease activity markers in their outcome measures...
October 31, 2016: Gut
https://www.readbyqxmd.com/read/27797273/wheat-challenge-in-self-reported-gluten-sensitivity-a-comparison-of-scoring-methods
#12
Gry I Skodje, Christine Henriksen, Trude Salte, Thea Drivenes, Ieva Toleikyte, Astrid M Lovik, Marit B Veierød, Knut E A Lundin
BACKGROUND: The condition non-coeliac gluten sensitivity (NCGS) is clinically similar to coeliac disease, but lack objective diagnostic criteria. Symptom relief on gluten-free diet followed by gluten containing food challenge may confirm the condition in clinical settings. AIM: To describe the results of an open bread challenge in patients with suspected NCGS, and to compare the results with recently suggested cut-offs for symptom change. MATERIAL AND METHODS: Fifty-six patients (12 males) self-instituted on gluten-free diet with negative coeliac disease diagnostics were examined for NCGS by an open bread challenge...
October 31, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27796452/development-and-optimisation-of-a-generic-micro-lc-esi-ms-method-for-the-qualitative-and-quantitative-determination-of-30-mer-toxic-gliadin-peptides-in-wheat-flour-for-food-analysis
#13
Bilgin Vatansever, Amalia Muñoz, Christoph L Klein, Knut Reinert
We sometimes see manufactured bakery products on the market which are labelled as being gluten free. Why is the content of such gluten proteins of importance for the fabrication of bakery industry and for the products? The gluten proteins represent up to 80 % of wheat proteins, and they are conventionally subdivided into gliadins and glutenins. Gliadins belong to the proline and glutamine-rich prolamin family. Its role in human gluten intolerance, as a consequence of its harmful effects, is well documented in the scientific literature...
October 28, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27794703/how-your-date-of-birth-may-determine-your-gluten-tolerance
#14
(no author information available yet)
The season in which you were born and even your place of birth could affect your risk of developing childhood coeliac disease.
September 7, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27787921/amelogenin-specific-iga-and-igg-in-children-with-untreated-coeliac-disease
#15
Sanja Petronijevic, Solveig Stig, Jian Gao, Trond S Halstensen
Children with untreated coeliac disease (CD) may develop enamel defects. Moreover, children with untreated CD have increased serum levels of gliadin reactive IgG, which may cross-react to amelogenin. The aim of this study was to investigate reactivity of anti-gliadin IgA and IgG to amelogenin in children with untreated CD. Blood samples from patients with CD (n = 75) and from disease controls (n = 24) were analysed for IgA and IgG reactivities to amelogenin (Emdogain) and to gliadin by ELISA. Whereas children with CD had statistically significantly higher serum levels of anti-amelogenin IgA, only those with the most severe CD (Marsh 3c) had significantly higher anti-amelogenin IgG immune reactivity than the disease controls...
December 2016: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/27782071/effect-of-bifidobacterium-breve-on-the-intestinal-microbiota-of-coeliac-children-on-a-gluten-free-diet-a-pilot-study
#16
Andrea Quagliariello, Irene Aloisio, Nicole Bozzi Cionci, Donata Luiselli, Giuseppe D'Auria, Llúcia Martinez-Priego, David Pérez-Villarroya, Tomaž Langerholc, Maša Primec, Dušanka Mičetić-Turk, Diana Di Gioia
Coeliac disease (CD) is associated with alterations of the intestinal microbiota. Although several Bifidobacterium strains showed anti-inflammatory activity and prevention of toxic gliadin peptides generation in vitro, few data are available on their efficacy when administered to CD subjects. This study evaluated the effect of administration for three months of a food supplement based on two Bifidobacterium breve strains (B632 and BR03) to restore the gut microbial balance in coeliac children on a gluten free diet (GFD)...
October 22, 2016: Nutrients
https://www.readbyqxmd.com/read/27769223/the-activities-of-a-dietitian-led-gastroenterology-clinic-using-extended-scope-of-practice
#17
Dominique Ryan, Fiona Pelly, Elizabeth Purcell
BACKGROUND: Extending the scope of practice of allied health professionals has been a strategy adopted in the United Kingdom to address issues within the health system. Australia's health system is currently undermined by similar issues, heightening government interest in adopting the extended scope health care model. The aim of the current study was to describe the activities and outcomes of a dietitian-led gastroenterology clinic which operated under an extended scope of practice model in an outpatient gastroenterology department at a tertiary hospital in regional Queensland, Australia, and to assess patient satisfaction with the initiative...
October 21, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27765787/nice-calls-for-wider-use-of-blood-tests-to-diagnose-coeliac-disease
#18
Jacqui Wise
No abstract text is available yet for this article.
October 20, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27743692/medical-students-perceptions-regarding-the-importance-of-nutritional-knowledge-and-their-confidence-in-providing-competent-nutrition-practice
#19
R Perlstein, S McCoombe, C Shaw, C Nowson
OBJECTIVES: The objective of this study was to examine the perceived importance, knowledge and confidence in nutritional management in a sample of Australian medical students undertaking a 4-year postgraduate medical degree. STUDY DESIGN/METHODS: In 2015, students in years 1-4 were anonymously surveyed to assess students' perceived importance of nutrition, and knowledge and confidence in nutritional management. RESULTS: A total of 131 first and second year (preclinical/yr 1-2) medical students (46% response rate) and 66 third and fourth year (clinical/yr 3-4) students (24% response rate) completed the questionnaire...
November 2016: Public Health
https://www.readbyqxmd.com/read/27728272/coeliac-disease-presenting-as-adult-onset-intractable-seizures
#20
A Raut, Bajrang K, U Sundar, S Honrao, N Inamdar
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
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