Read by QxMD icon Read

Transcranial alternating current

Alessia Gallucci, Pedro H Lucena, Géraldine Martens, Aurore Thibaut, Felipe Fregni
Opioid misuse leading to dependence is a major health issue. Recent studies explored valid alternatives to treat pain in postsurgical settings. This systematic review aims to discuss the role of transcranial direct current stimulation (tDCS) in preventing and treating postoperative pain and opioid dependence. PubMed and Embase databases were screened, considering studies testing tDCS effects on pain and opioid consumption in surgical settings and opioid addiction. Eight studies met our inclusion criteria...
December 5, 2018: Pain Management
Danielle D Sliva, Christopher J Black, Paul Bowary, Uday Agrawal, Juan F Santoyo, Noah S Philip, Benjamin D Greenberg, Christopher I Moore, Stephanie R Jones
The (8-12 Hz) neocortical alpha rhythm is associated with shifts in attention across sensory systems, and is thought to represent a sensory gating mechanism for the inhibitory control of cortical processing. The present preliminary study sought to explore whether alpha frequency transcranial alternating current stimulation (tACS) could modulate endogenous alpha power in the somatosensory system, and whether the hypothesized modulation would causally impact perception of tactile stimuli at perceptual threshold...
2018: Frontiers in Psychology
Anli Liu, Mihály Vöröslakos, Greg Kronberg, Simon Henin, Matthew R Krause, Yu Huang, Alexander Opitz, Ashesh Mehta, Christopher C Pack, Bart Krekelberg, Antal Berényi, Lucas C Parra, Lucia Melloni, Orrin Devinsky, György Buzsáki
Noninvasive brain stimulation techniques are used in experimental and clinical fields for their potential effects on brain network dynamics and behavior. Transcranial electrical stimulation (TES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), has gained popularity because of its convenience and potential as a chronic therapy. However, a mechanistic understanding of TES has lagged behind its widespread adoption. Here, we review data and modelling on the immediate neurophysiological effects of TES in vitro as well as in vivo in both humans and other animals...
November 30, 2018: Nature Communications
Charles S H Robinson, Natalie B Bryant, Joshua W Maxwell, Aaron P Jones, Bradley Robert, Melanie Lamphere, Angela Combs, Hussein M Al Azzawi, Benjamin C Gibson, Joseph L Sanguinetti, Nicholas A Ketz, Praveen K Pilly, Vincent P Clark
BACKGROUND: Poor sleep quality is a common complaint, affecting over one third of people in the United States. While sleep quality is thought to be related to slow-wave sleep (SWS), there has been little investigation to address whether modulating slow-wave oscillations (SWOs) that characterize SWS could impact sleep quality. Here we examined whether closed-loop transcranial alternating current stimulation (CL-tACS) applied during sleep impacts sleep quality and efficiency. METHODS: CL-tACS was used in 21 participants delivered at the same frequency and in phase with endogenous SWOs during sleep...
November 22, 2018: Brain Sciences
Ignacio Jáuregui-Lobera, José V Martínez-Quiñones
Neuromodulation can affect the functioning of the central nervous system (CNS), and emotional/eating behavior is an exciting facet of that functioning. Therefore, it would be possible to offer an alternative (or complement) treatment to psychotropic medications and different psychological and nutritional approaches to both eating disorders (EDs) and obesity. Although there are a number of publications in these areas, a systematic review has not been conducted to date. Abstracts, letters, conference reports, dissertations, and reviews were excluded...
2018: Neuropsychiatric Disease and Treatment
Samar S Ayache, Moussa A Chalah
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, characterized by chronic inflammation, demyelination, synaptopathy and neurodegeneration. Patients may exhibit sensory, motor, cognitive, emotional and behavioral symptoms throughout their disease process. Nowadays, the challenge is to find optimal treatment for MS symptoms, especially that available pharmacological interventions are faced by modest therapeutic outcomes and numerous side effects. Thus, finding alternative strategies might be of help in this context...
December 2018: Neurodegenerative Disease Management
Suellen Marinho Andrade, Eliane Araújo de Oliveira, Nelson Torro Alves, Ana Cristina Gomes Dos Santos, Camila Teresa Ponce Leon de Mendonça, Danielle Dorand Amorim Sampaio, Edyllaine Elidy Querino Cavalcante da Silva, Égina Karoline Gonçalves da Fonsêca, Evelyn Thais de Almeida Rodrigues, Gabriela Nayara Siqueira de Lima, Jamerson Carvalho, Jessyca Alves Silvestre da Silva, Manuella Toledo, Marine Raquel Diniz da Rosa, Marcia Queiroz de Carvalho Gomes, Melquisedek Monteiro de Oliveira, Moema Teixeira Maia Lemos, Nágylla Gomes Lima, Penha Inácio, Petra Maria da Cruz Ribeiro E Rodrigues, Rayssa Gabriela Dantas Ferreira, Renata Cavalcante, Renata Emanuela Lyra de Brito Aranha, Regina Neves, Rodrigo Marmo da Costa E Souza, Thainá Magalhães Portugal, Wanessa Kallyne Nascimento Martins, Vivian Pontes, Thiago Monteiro de Paiva Fernandes, Israel Contador, Bernardino Fernández-Calvo
Despite advances in the treatment of Alzheimer's disease (AD), there is currently no prospect of a cure, and evidence shows that multifactorial interventions can benefit patients. A promising therapeutic alternative is the use of transcranial direct current stimulation (tDCS) simultaneously with cognitive intervention. The combination of these non-pharmacological techniques is apparently a safe and accessible approach. This study protocol aims to compare the efficacy of tDCS and cognitive intervention in a double-blind, randomized and factorial clinical trial...
2018: Frontiers in Aging Neuroscience
Shota Miyaguchi, Naofumi Otsuru, Sho Kojima, Hirotake Yokota, Kei Saito, Yasuto Inukai, Hideaki Onishi
Transcranial alternating current stimulation (tACS) modulates neural connectivity in the cortical area under the electrodes. Although gamma tACS over the M1 and the cerebellar hemisphere has been shown to improve motor performance, the details of this effect remain unclear. This study aimed to clarify whether the effect of gamma tACS over the M1 and the cerebellar hemisphere is a phase-specific. We applied tACS at 70 Hz over the left M1 and the right cerebellar hemisphere to 20 healthy adults while they performed a visuomotor control task using their right index finger for 30 s...
November 13, 2018: Neuroscience Letters
Huanhuan Cui, Jinwen Wei, Yufeng Ke, Xingwei An, Chang Sun, Minpeng Xu, Hongzhi Qi, Dong Ming, Peng Zhou
Vigilant attention plays an important role in some industries and everyday life. However, the relationship between the variation of vigilant attention and phase synchronization is still unknown. This study utilized a revised version of the psychomotor vigilance test (PVT) to elicit vigilance decrement while collecting electroencephalogram (EEG) and using inter-site phase clustering (ISPC) to analyze phase synchronization. The theta tACS modulates phase synchronization between LPFC and MPFC so as to affect the performance of vigilant attention...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Thomas M Kinfe, René Hurlemann
Given that one third of patients with schizophrenia (SZ) only show limited response to established treatments, alternative therapeutic strategies such as non-invasive/invasive brain stimulation approaches have emerged as an adjunctive treatment option for distinct SZ symptom domains (e.g. acoustic hallucinations, negative/positive symptoms and cognitive impairment). aking comparative interventional studies and standardized technical parameters into consideration, current meta-analyses indicate that adjunctive electroconvulsive therapy, repetitive transcranial magnetic stimulation and transcranial direct current stimulation have a positive effect...
November 14, 2018: Der Nervenarzt
Gaëlle Dumel, Marie-Eve Bourassa, Camille Charlebois-Plante, Martine Desjardins, Julien Doyon, Dave Saint-Amour, Louis De Beaumont
Healthy aging is associated with decline of motor function that can generate serious consequences on the quality of life and safety. Our studies aim to explore the 3-month effects of a 5-day multisession anodal transcranial direct current stimulation (a-tDCS) protocol applied over the primary motor cortex (M1) during motor sequence learning in elderly. The present sham-controlled aging study investigated whether tDCS-induced motor improvements previously observed 1 day after the intervention persist beyond 3 months...
2018: Frontiers in Aging Neuroscience
Franziska Röhner, Carolin Breitling, Katharina S Rufener, Hans-Jochen Heinze, Hermann Hinrichs, Kerstin Krauel, Catherine M Sweeney-Reed
Transcranial electrical stimulation (TES) has been considered a promising tool for improving working memory (WM) performance. Recent studies have demonstrated modulation of networks underpinning WM processing through application of transcranial alternating current (TACS) as well as direct current (TDCS) stimulation. Differences between study designs have limited direct comparison of the efficacy of these approaches, however. Here we directly compared the effects of theta TACS (6 Hz) and anodal TDCS on WM, applying TACS to the frontal-parietal loop and TDCS to the dorsolateral prefrontal cortex (DLPFC)...
2018: Frontiers in Neuroscience
Wan-Yu Hsu, Theodore P Zanto, Adam Gazzaley
BACKGROUND: We have previously demonstrated that transcranial alternating current stimulation (tACS) can generate positive effects on multitasking performance and associated neurophysiological measures when it is applied with anti-phase theta band stimulation across bilateral prefrontal cortex (PFC) and a short (1-min) inter-session interval (ISI). However, it is unclear how altering the phase of stimulation and the duration of the ISI might impact positive tACS effects. Here, we investigated the role of tACS parameters in engendering performance improvements by manipulating these two stimulation parameters (i...
October 23, 2018: Brain Stimulation
Sangtae Ahn, Juliann M Mellin, Sankaraleengam Alagapan, Morgan L Alexander, John H Gilmore, L Fredrik Jarskog, Flavio Fröhlich
Transcranial alternating current stimulation (tACS) modulates endogenous neural oscillations in healthy human participants by the application of a low-amplitude electrical current with a periodic stimulation waveform. Yet, it is unclear if tACS can modulate and restore neural oscillations that are reduced in patients with psychiatric illnesses such as schizophrenia. Here, we asked if tACS modulates network oscillations in schizophrenia. We performed a randomized, double-blind, sham-controlled clinical trial to contrast tACS with transcranial direct current stimulation (tDCS) and sham stimulation in 22 schizophrenia patients with auditory hallucinations...
October 24, 2018: NeuroImage
X Moisset, J-P Lefaucheur
The use of medications in chronic neuropathic pain may be limited with regard to efficacy and tolerance. Therefore, non-pharmacological approaches, using electrical stimulation of the cortex has been proposed as an alternative. First, in the early nineties, surgically-implanted epidural motor cortex stimulation (EMCS) was proven to be effective to relieve refractory neuropathic pain. Later, non-invasive stimulation techniques were found to produce similar analgesic effects, at least by means of repetitive transcranial magnetic stimulation (rTMS) targeting the primary motor cortex (M1)...
October 12, 2018: Revue Neurologique
B Chi, B Chau, E Yeo, P Ta
BACKGROUND: Treatment of spinal cord injury (SCI)-associated neuropathic pain is challenging, with limited efficacy and no definitive options, and SCI patients often show resistance to pharmacologic treatment. Virtual reality (VR) therapy is a non-invasive, non-pharmacologic alternative with minimal adverse effects. OBJECTIVE: To investigate the effect of VR therapy on SCI-associated neuropathic pain in a systematic review. METHODS: Articles needed to 1) be written in English; 2) include adult subjects, with at least half the study population with a SCI diagnosis; 3) involve any form of VR therapy; and 4) assess neuropathic pain by quantitative outcome measures...
October 9, 2018: Annals of Physical and Rehabilitation Medicine
Eduardo de Souza Nicolau, Kevin Augusto Farias de Alvarenga, Helia Tenza-Ferrer, Matheus Carvalho Alves Nogueira, Fernanda Donizete Rezende, Nycolle Ferreira Nicolau, Mélcar Collodetti, Débora Marques de Miranda, Luiz Alexandre Viana Magno, Marco Aurélio Romano-Silva
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique proposed as an alternative or complementary treatment for several neuropsychiatric diseases. The biological effects of tDCS are not fully understood, which is in part explained due to the difficulty in obtaining human brain tissue. This protocol describes a tDCS mouse model that uses a chronically implanted electrode allowing the study of the long-lasting biological effects of tDCS. In this experimental model, tDCS changes the cortical gene expression and offers a prominent contribution to the understanding of the rationale for its therapeutic use...
September 23, 2018: Journal of Visualized Experiments: JoVE
A K Martin, J Huang, A Hunold, M Meinzer
Theories of right temporoparietal junction (rTPJ) function in social cognition include self-other distinction, self-inhibition, or embodied rotation, whereas the dorsomedial prefrontal cortex (dmPFC) is associated with integrating social information. However, no study has provided causal evidence for dissociable roles of the rTPJ and dmPFC in social cognition. A total of 52 healthy young adults were stratified to receive either dmPFC or rTPJ anodal high-definition transcranial direct current stimulation (HD-tDCS) in a sham-controlled, double-blinded, repeated measures design...
October 1, 2018: Cerebral Cortex
Gabriele Fusco, Michele Scandola, Matteo Feurra, Enea F Pavone, Simone Rossi, Salvatore M Aglioti
Cognitive control during conflict monitoring, error processing, and post-error adjustment appear to be associated with the occurrence of midfrontal theta (MFϴ). While this association is supported by correlational EEG studies, much less is known about the possible causal link between MFϴ and error and conflict processing. In the present study, we aimed to explore the role of band-specific effects in modulating the error system during a conflict resolution. In turn, we delivered transcranial alternating current stimulation (tACS) at different frequency bands (delta δ, theta θ, alpha α, beta β, gamma γ) and sham stimulation over the medial frontal cortex (MFC) in 36 healthy participants performing a modified version of the Flanker task...
September 30, 2018: European Journal of Neuroscience
Sangtae Ahn, Julianna H Prim, Morgan L Alexander, Karen L McCulloch, Flavio Fröhlich
Chronic pain is associated with maladaptive reorganization of the central nervous system. Recent studies have suggested that disorganization of large-scale electrical brain activity patterns, such as neuronal network oscillations in the thalamocortical system, plays a key role in the pathophysiology of chronic pain. Yet, little is known about whether and how such network pathologies can be targeted with noninvasive brain stimulation as a nonpharmacological treatment option. We hypothesized that alpha oscillations, a prominent thalamocortical activity pattern in the human brain, are impaired in chronic pain and can be modulated with transcranial alternating current stimulation (tACS)...
September 27, 2018: Journal of Pain: Official Journal of the American Pain Society
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"