keyword
MENU ▼
Read by QxMD icon Read
search

Predictive value

keyword
https://www.readbyqxmd.com/read/29031218/termination-patterns-of-stimulus-induced-rhythmic-periodic-or-ictal-patterns-and-spontaneous-electrographic-seizures
#1
Emily L Johnson, Peter W Kaplan, Eva K Ritzl
OBJECTIVE: To investigate the ability of the evolution and termination patterns to distinguish stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs) from spontaneous electrographic seizures, a challenge to the neurophysiologist and clinician. METHODS: We screened the prospectively collected database of patients undergoing continuous EEG (cEEG) and identified 25 cases of SIRPIDs. We compared patients with SIRPIDs to 25 patients with spontaneous seizures...
September 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29031015/the-venous-thromboembolic-risk-and-the-clot-wave-analysis-a-useful-relationship
#2
Maria Filomena Ruberto, Francesco Marongiu, Antonella Mandas, Antonella Mameli, Mariagrazia Porru, Elisabetta Cianchetti, Doris Barcellona
BACKGROUND: Hospitalized patients with acute medical conditions have higher venous thromboembolism (VTE) risk. A patient with a final Padua Prediction Score (PPS) of ≥4 is considered to be at high risk for VTE. The aim of this study was to investigate on a possible relationship between PPS, the dynamics of the clot formation, i.e. the clot waveform analysis (CWA) of aPTT, fibrinogen and D-Dimer in a large group of medical patients. METHODS: CWA in terms of velocity (first derivative), acceleration (second derivative), density (Delta) of aPTT, fibrinogen, D-Dimer and PPS for VTE were determined in 801 medical patients divided in three groups (without antithrombotic prophylaxis and high PPS, without antithrombotic prophylaxis and low PPS, with antithrombotic prophylaxis and high PPS) and a group of healthy subjects...
October 14, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29029343/an-evaluation-of-different-partitioning-strategies-for-bayesian-estimation-of-species-divergence-times
#3
Konstantinos Angelis, Sandra Álvarez-Carretero, Mario Dos Reis, Ziheng Yang
The explosive growth of molecular sequence data has made it possible to estimate species divergence times under relaxed-clock models using genome-scale data sets with many gene loci. In order to improve both model realism and to best extract information about relative divergence times in the sequence data, it is important to account for the heterogeneity in the evolutionary process across genes or genomic regions. Partitioning is a commonly used approach to achieve those goals. We group sites that have similar evolutionary characteristics into the same partition and those with different characteristics into different partitions, and then use different models or different values of model parameters for different partitions to account for the among-partition heterogeneity...
July 4, 2017: Systematic Biology
https://www.readbyqxmd.com/read/29029029/a-manifesto-for-cardiovascular-imaging-addressing-the-human-factor
#4
Alan G Fraser
Our use of modern cardiovascular imaging tools has not kept pace with their technological development. Diagnostic errors are common but seldom investigated systematically. Rather than more impressive pictures, our main goal should be more precise tests of function which we select because their appropriate use has therapeutic implications which in turn have a beneficial impact on morbidity or mortality. We should practise analytical thinking, use checklists to avoid diagnostic pitfalls, and apply strategies that will reduce biases and avoid overdiagnosis...
September 28, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29028985/impact-of-coronary-lumen-reconstruction-on-the-estimation-of-endothelial-shear-stress-in-vivo-comparison-of-three-dimensional-quantitative-coronary-angiography-and-three-dimensional-fusion-combining-optical-coherent-tomography
#5
Jihoon Kweon, Soo-Jin Kang, Young-Hak Kim, June-Goo Lee, Seungbong Han, Hojin Ha, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Osung Kwon, Jung-Min Ahn, Pil Hyung Lee, Duk-Woo Park, Seung-Whan Lee, Cheol Whan Lee, Seong-Wook Park, Seung-Jung Park
Aims: It is not clearly elucidated how the fusion technique improves the accuracy of endothelial shear stress (ESS) prediction, in comparison with that of three-dimensional (3D) quantitative coronary angiography (QCA) alone. We aimed to evaluate the difference in geometric measurements and haemodynamic estimation between 3D QCA and a 3D fusion model combining 3D QCA and optical coherence tomography (OCT). Methods and results: Computational fluid dynamics was assessed in the coronary models of 20 patients...
September 25, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29028932/surgical-pleth-index-prediction-of-postoperative-pain-in-children
#6
T Ledowski, D Sommerfield, L Slevin, J Conrad, B S von Ungern-Sternberg
Background: Surgical Pleth Index (SPI) is a non-invasive, dimensionless score (0-100) aimed to allow an estimate of intraoperative nociception. Thus, it may be a useful tool to guide intraoperative analgesia. However, no optimum SPI target range for the use in children has yet been defined. It was the aim of this study to define a clinically appropriate SPI target to predict moderate-severe postoperative pain in children. Methods: After ethics approval 105 children (2-16 yr) undergoing elective sevoflurane/opioid-based anaesthesia were included...
October 4, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29028901/a-collaborative-filtering-based-approach-to-biomedical-knowledge-discovery
#7
Jake Lever, Sitanshu Gakkhar, Michael Gottlieb, Tahereh Rashnavadi, Santina Lin, Celia Siu, Maia Smith, Martin Jones, Martin Krzywinski, Steven J Jones
Motivation: The increase in publication rates makes it challenging for an individual researcher to stay abreast of all relevant research in order to find novel research hypotheses. Literature-based discovery methods make use of knowledge graphs built using text mining and can infer future associations between biomedical concepts that will likely occur in new publications. These predictions are a valuable resource for researchers to explore a research topic. Current methods for prediction are based on the local structure of the knowledge graph...
September 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29028891/on-the-mechanisms-of-protein-interactions-predicting-their-affinity-from-unbound-tertiary-structures
#8
Manuel Alejandro Marín-López, Joan Planas-Iglesias, Joaquim Aguirre-Plans, Jaume Bonet, Javier Garcia-Garcia, Narcis Fernandez-Fuentes, Baldo Oliva
Motivation: The characterization of the protein-protein association mechanisms is crucial to understanding how biological processes occur. It has been previously shown that the early formation of non-specific encounters enhances the realization of the stereospecific (i.e. native) complex by reducing the dimensionality of the search process. The association rate for the formation of such complex plays a crucial role in the cell biology and depends on how the partners diffuse to be close to each other...
September 27, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29028764/the-prognostic-value-of-mri-in-moderate-and-severe-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#9
Hourmazd Haghbayan, Amélie Boutin, Mathieu Laflamme, François Lauzier, Michèle Shemilt, Lynne Moore, Ryan Zarychanski, Vincent Douville, Dean Fergusson, Alexis F Turgeon
OBJECTIVES: Traumatic brain injury is a major cause of death and disability, yet many predictors of outcome are not precise enough to guide initial clinical decision-making. Although increasingly used in the early phase following traumatic brain injury, the prognostic utility of MRI remains uncertain. We thus undertook a systematic review and meta-analysis of studies evaluating the predictive value of acute MRI lesion patterns for discriminating clinical outcome in traumatic brain injury...
October 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29028737/resting-pd-pa-and-haemodynamic-relevance-of-coronary-stenosis-as-evaluated-by-fractional-flow-reserve
#10
Giuseppe De Luca, Monica Verdoia, Lucia Barbieri, Paolo Marino, Harry Suryapranata
BACKGROUND: Fractional flow reserve (FFR) currently represents the gold standard in the evaluation of the haemodynamic relevance of coronary stenoses. However, both intracoronary and intravenous adenosine may be tolerated poorly by some patients. Therefore, considerable interest had been focused in the last few years on new adenosine-free indexes to define the haemodynamic relevance of coronary stenoses. So far, few data have been reported on resting Pd/Pa and its correlation with FFR as evaluated with high-dose intracoronary adenosine administration, which is the aim of the current study...
October 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29028601/developing-predictive-models-for-toxicity-of-organic-chemicals-to-green-algae-based-on-mode-of-action
#11
Serge Bakire, Xinya Yang, Guangcai Ma, Xiaoxuan Wei, Haiying Yu, Jianrong Chen, Hongjun Lin
Organic chemicals in the aquatic ecosystem may inhibit algae growth and subsequently lead to the decline of primary productivity. Growth inhibition tests are required for ecotoxicological assessments for regulatory purposes. In silico study is playing an important role in replacing or reducing animal tests and decreasing experimental expense due to its efficiency. In this work, a series of theoretical models was developed for predicting algal growth inhibition (log EC50) after 72 h exposure to diverse chemicals...
October 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/29028571/identifying-ovarian-tissue-in-the-bitch-using-anti-m%C3%A3-llerian-hormone-amh-or-luteinizing-hormone-lh
#12
Helene Alm, Bodil S Holst
Reliable methods for determining whether or not a bitch has ovarian tissue present are needed for cases with unknown neutering status. Vaginal cytology consistent with heat is indicative of functional ovarian tissue. Other methods are required when the bitch is not presented in suspected heat. Progesterone can be analyzed during 2 months after suspected heat. During other stages, assays for the analyses of anti-Müllerian hormone (AMH) and luteinizing hormone (LH) have been used. The AMH assay is expected to give detectable concentrations (positive) in bitches with ovarian tissue, and the LH assay should give negative results in intact bitches, except during the pre-ovulatory LH peak...
September 27, 2017: Theriogenology
https://www.readbyqxmd.com/read/29028360/a-predictive-model-for-the-growth-of-listeria-monocytogenes-in-commercial-blue-crab-callinectes-sapidus
#13
Salina Parveen, Channel White, Mark L Tamplin
During the processing and handling of commercial blue crab (Callinectes sapidus), Listeria monocytogenes can potentially contaminate cooked meat and grow to hazardous levels. To manage this risk, predictive models are useful tools for designing and implementing preventive controls; however, no model specific for blue crab meat has been published or evaluated. In this study, a cocktail of L. monocytogenes strains was added to pasteurized blue crab meat, which was incubated at storage temperatures from 0 to 35°C...
October 13, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/29028281/usefulness-of-the-index-of-nash-ion-for-the-diagnosis-of-steatohepatitis-in-patients-with-non-alcoholic-fatty-liver-an-external-validation-study
#14
Ramy Younes, Chiara Rosso, Salvatore Petta, Monica Cucco, Milena Marietti, Gian Paolo Caviglia, Alessia Ciancio, Maria Lorena Abate, Carlo Cammà, Antonina Smedile, Antonio Craxì, Giorgio Maria Saracco, Elisabetta Bugianesi
BACKGROUND & AIMS: The non-invasive identification of steatohepatitis (NASH) in patients with Non-Alcoholic Fatty Liver Disease is an unmet need in clinical practice. Index of NASH (ION) is a new tool for the prediction of NASH. We aimed to externally validate ION and to compare it with CK-18. Since necroinflammation precedes fibrosis, we also tested ION in combination with non-invasive tools for fibrosis. METHODS: We analyzed data from 292 Italian patients (169 Southern cohort, and 123 Northern cohort) with an histological diagnosis of NAFLD...
October 13, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29028279/liver-elastography-malignancy-prediction-lemp-score-for-noninvasive-characterization-of-focal-liver-lesions
#15
Ivica Grgurevic, Tomislav Bokun, Nermin N Salkic, Boris Brkljacic, Mirjana Vukelić-Markovic, Tajana Stoos-Veic, Gorana Aralica, Mislav Rakic, Tajana Filipec-Kanizaj, Annalisa Berzigotti
BACKGROUND & AIMS: To analyse elastographic characteristics of focal liver lesions (FLL)s and diagnostic performance of real-time two-dimensional shear-wave elastography (RT-2D-SWE) in order to differentiate benign and malignant FLLs. PATIENTS AND METHODS: Consecutive patients diagnosed with FLL by abdominal ultrasound (US) underwent RT-2D-SWE of FLL and non-infiltrated liver by intercostal approach over the right liver lobe. The nature of FLL was determined by diagnostic work-up, including at least one contrast-enhanced imaging modality (MDCT/MRI), check-up of target organs when metastatic disease was suspected and FLL biopsy in inconclusive cases...
October 13, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29028212/a-novel-error-compensation-control-for-a-class-of-high-order-nonlinear-systems-with-input-delay
#16
Chao Shi, Zongcheng Liu, Xinmin Dong, Yong Chen
A novel tracking error-compensation-based adaptive neural control scheme is proposed for a class of high-order nonlinear systems with completely unknown nonlinearities and input delay. In the tracking errors of existing papers, there exist the following difficulties: first, output curve always lags behind the desired trajectory, second, some big peak errors cause a decrease in tracking precision, and third, a big initial value of the modified tracking error can make the closed-loop system unstable. To tackle them, three corresponding error-compensation terms are constructed, including a prediction and compensation term, an auxiliary signal produced by the constructed auxiliary system, and a damping term...
October 10, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/29028128/diagnostic-accuracy-of-magnetic-resonance-imaging-hepatic-proton-density-fat-fraction-in-pediatric-nonalcoholic-fatty-liver-disease
#17
Michael S Middleton, Mark L Van Natta, Elhamy R Heba, Adina Alazraki, Andrew T Trout, Prakash Masand, Elizabeth M Brunt, David E Kleiner, Edward Doo, James Tonascia, Joel E Lavine, Wei Shen, Gavin Hamilton, Jeffrey B Schwimmer, Claude B Sirlin
We assessed the performance of magnetic resonance imaging (MRI) proton density fat fraction (PDFF) in children to stratify hepatic steatosis grade before and after treatment in the Cysteamine Bitartrate Delayed-Release for the Treatment of Nonalcoholic Fatty Liver Disease in Children (CyNCh) trial, using centrally-scored histology as reference. Participants had multi-echo 1.5T or 3T MRI on scanners from three manufacturers. Of 169 enrolled children, 110 (65%) and 83 (49%) had MRI and liver biopsy at baseline and at end-of-treatment (EOT; 52-weeks), respectively...
October 13, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29028098/down-regulation-of-mir-329-3p-is-associated-with-worse-prognosis-in-patients-with-cervical-cancer
#18
Y-H Chang, F Yin, G-F Fan, M Zhao
OBJECTIVE: miR-329-3p has been reported to serve as a tumor suppressor in the progression of cervical cancer (CC). The aim of this study was to investigate the clinical significance of miR-329-3p in human CC. PATIENTS AND METHODS: Quantitative RT-PCR (qRT-PCR) was used to detect miR-329-3p expression in CC tissue samples and matched normal cervical tissues. The x2 test was used to analyze the association between miR-329-3p expression and clinical features of CC patients...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29028092/long-non-coding-rna-ror-is-a-novel-prognosis-factor-associated-with-non-small-cell-lung-cancer-progression
#19
C-H Qu, Q-Y Sun, F-M Zhang, Y-M Jia
OBJECTIVE: The aim of the present study was to determine the expression levels of long intergenic non-protein coding RNA, regulator of reprogramming (linc-ROR) in non-small-cell lung cancer (NSCLC) patients and to further explore the prognostic value of this lncRNA. PATIENTS AND METHODS: In our investigation, we determined the expression of linc-ROR in human NSCLC tissues and matched normal lung tissues by quantitative Real-time-PCR analysis. Also, correlations between linc-ROR expression and the clinicopathological features were evaluated...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29028091/investigation-of-serum-mir-411-as-a-diagnosis-and-prognosis-biomarker-for-non-small-cell-lung-cancer
#20
S-Y Wang, Y Li, Y-S Jiang, R-Z Li
OBJECTIVE: Biomarkers in blood have become increasingly appreciated in the diagnosis and prognosis of non-small cell lung cancer (NSCLC). The purpose of the current study was to explore potential diagnostic and prognostic value of serum miR-411 in NSCLC patients. PATIENTS AND METHODS: 153 patients with NSCLC and 75 healthy controls were enrolled in the study. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was performed to determine the expression level of serum miR-411 in NSCLC patients and healthy controls...
September 2017: European Review for Medical and Pharmacological Sciences
keyword
keyword
16189
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"