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Opthalmology

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https://www.readbyqxmd.com/read/27796155/investigation-of-the-effects-of-systemic-isotretinoin-treatment-on-retinal-nerve-fiber-layer-and-macula
#1
Uğur Yılmaz, Erkut Kucuk, Cagdas Koc, Ayse Ozkose
PURPOSE: To investigate the effects of systemic isotretinoin therapy on retina by measuring retinal nevre fiber layer(RNFL) and macular thicknesses. METHOD: This prospective, cross-sectional study was conducted in patients prescribed systemic isotretinoin therapy. 72 eyes of 36 patients were included in the study. The patients were followed during three months. Detailed opthalmologic examination including anterior and posterior segment examination, best corrected visual acuity and intraocular pressure measurement, RNFL and macular thicknesses measurement by Spectral Domain Cirrus Optical Coherence Tomography Model 400 (Carl Zeiss Meditech, Jena, Germany) were performed at baseline, first, second and third months after the beginning of systemic isotretinoin therapy in ophthalmology clinic...
October 31, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27608700/systemic-lupus-erythematosus-presenting-as-neuroretinitis
#2
Gouranga Santra, Indrani Das
Neuroretinitis is the inflammation of retina and optic nerve. It is associated with optic disc edema accompanied by peripapillary or macular hard exudates. A 17 yr old female presented with headache and nausea of five days duration. She had periorbital edema and mild splenomegaly. Neurological assessment was non-contributory. She was found to have pancytopenia, albuminuria and a high ESR. Thereafter she developed blurring of vision of both eyes. Opthalmological examination showed it to be due to bilateral neuroretinitis...
October 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27575526/-turner-syndrome-study-of-42-cases
#3
M Pilar Bahíllo-Curieses, Pablo Prieto-Matos, Rocío Quiroga González, Laura Regueras Santos, Amaya Blanco Barrio, Sara Rupérez Peña
BACKGROUND AND OBJECTIVE: Turner syndrome (TS) is characterized by short stature, gonadal dysgenesis, and total or partial loss of X chromosome. PATIENTS AND METHODS: A historical cohorts study of patients with TS≤18 years old followed up in public hospitals in Castilla y Leon was undertaken. RESULTS: Forty-two female patients were included (prenatal diagnosis 11.9%, neonatal diagnosis 14.3%) with current median age 11.9±4.2 years. Short stature was the reason for consultation in 87...
October 21, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27393804/retinal-blood-vessel-extraction-using-tunable-bandpass-filter-and-fuzzy-conditional-entropy
#4
Sudeshna Sil Kar, Santi P Maity
BACKGROUND AND OBJECTIVES: Extraction of blood vessels on retinal images plays a significant role for screening of different opthalmologic diseases. However, accurate extraction of the entire and individual type of vessel silhouette from the noisy images with poorly illuminated background is a complicated task. To this aim, an integrated system design platform is suggested in this work for vessel extraction using a sequential bandpass filter followed by fuzzy conditional entropy maximization on matched filter response...
September 2016: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27293250/xanthelasma-palpebrarum-with-arcus-cornea-a-clinical-and-biochemical-study
#5
Pragya Ashok Nair, Chaitali R Patel, Jaishree D Ganjiwale, Nilofar Gulamsha Diwan, Nidhi Bhimjibhai Jivani
BACKGROUND: Xanthelasma palpebrarum (XP) is characterized by sharply demarcated yellowish flat plaques on upper and lower eyelids. It is commonly seen in women with a peak incidence at 30-50 years. It is also considered as the cutaneous marker of underlying atherosclerosis along with the disturbed lipid metabolism. XP and corneal arcus are associated with increased levels of serum cholesterol and low-density lipoprotein (LDL) cholesterol. AIMS AND OBJECTIVES: To study the clinical pattern of XP, its relationship with lipid profile and association with arcus cornea...
May 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/26894082/antecedent-drug-exposure-aetiology-and-management-protocols-in-steven-johnson-syndrome-and-toxic-epidermal-necrolysis-a-hospital-based-prospective-study
#6
Samina Farhat, Muddasir Banday, Iffat Hassan
AIM: The study sought to identify the magnitude and characteristic of severe cutaneous adverse reactions (SCAR's) like Steven-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). MATERIALS AND METHODS: A prospective study was conducted by the Department of Pharmacology in association with Department of Dermatology in SMHS hospital. The study was carried out from June 2013-June 2015 on hospitalized cases of cutaneous adverse drug reaction reporting in hospital...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26842341/predictive-factors-for-ocular-complications-caused-by-anticancer-drug-s-1
#7
Rika Yamada, Chie Sotozono, Takahiro Nakamura, Akihiro Nishida, Shinya Nakanishi, Masaki Hirabatake, Akihito Tsuji, Yasuo Kurimoto
PURPOSE: To identify predictive factors for ocular complications caused by the anticancer drug S-1. METHODS: A questionnaire was administered to 39 patients who underwent S-1 chemotherapy at Kobe City Medical Center General Hospital, with the aim to determine whether these patients were aware of the ocular complications caused by S-1. Cognition rate was determined. The 26 patients who requested opthalmological examination for further evaluation studied further and classified into two groups-those who had developed corneal epithelial complications, conjunctival injection or chemosis, or lacrimal duct blockages (referred to as the positive group) and those without these findings (referred to as the negative group)...
March 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/26689876/lyme-disease-associated-neuroretinitis-case-report
#8
Melinda Vanya, Imre Fejes, Maria Jako, Areta Tula, Gabriella Terhes, Marta Janaky, Gyorgy Bartfai
We describe a rare case of Lyme disease complicated by unilateral neuroretinitis in the right eye. We report a case of a 27-year-old woman with blurred vision on her right eye. Because of the suspicion of optic neuritis (multiplex sclerosis) neurological examination was ordered. Surprisingly, computer tomography of the brain revealed incomplete empty sella, which generally results not monocular, but bilateral optic nerve swelling. Opthalmological examination (ophthalmoscopy and optical coherence tomography) indicated not only monocular optic nerve, but retinal oedema next to the temporal part of the right optic disk...
December 2015: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/26023269/vision-related-problems-among-the-workers-engaged-in-jewellery-manufacturing
#9
Urmi Ravindra Salve
BACKGROUND: American Optometric Association defines Computer Vision Syndrome (CVS) as "complex of eye and vision problems related to near work which are experienced during or related to computer use." This happens when visual demand of the tasks exceeds the visual ability of the users. Even though problems were initially attributed to computer-related activities subsequently similar problems are also reported while carrying any near point task. Jewellery manufacturing activities involves precision designs, setting the tiny metals and stones which requires high visual attention and mental concentration and are often near point task...
January 2015: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/25830057/repeated-intramuscular-dose-toxicity-test-of-watersoluble-carthami-flos-wcf-pharmacopuncture-in-sprague-dawley-rats
#10
Yoo-Min Choi, Da-Jung Jung, Seok-Hee Kim, Jong-Uk Kim, Tae-Han Yook
OBJECTIVES: Water-soluble carthami flos (WCF) is a new mixture of Carthami flos (CF) pharmacopuncture. We conducted a 4-week toxicity test of repeated intramuscular injections of WCF in Sprague-Dawley rats. METHODS: Forty male and 40 female rats were divided into 4 groups of 10 male and 10 female SD rats: The control group received 0.5 mL/animal/day of normal saline whereas the three experimental groups received WCF at doses of 0.125, 0.25, and 0.5 mL/animal/day, respectively...
March 2015: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/25568537/treatment-of-congenital-aniridia-associated-with-subluxated-infantile-cataract
#11
Vahid Jusufovic, Emir Cabric, Allen Popovic-Beganovic, Zlatko Musanovic, Jasmin Zvornicanin
A 5 year old boy was presented at Eye clinic University clinical center Tuzla with congenital aniridia in both eyes. Clinical examination revealed visual acuity of 0,08 without correction in right and 0.7 with -5.0 Dsph and -1.0 Dcyl Axx 109° in left eye. Opthalmologic examination showed bilateral aniridia associated with moderate cataract in the right and incipient cataract in the left eye. In the right eye, zonular weakness with incipient capsular displacement and esotropia of Δ6º, were noted. The patient underwent phacoemulsification, implantation of capsular tension ring and Artificial Iris implant in the capsular bag...
June 2014: Medical Archives
https://www.readbyqxmd.com/read/25546496/poliosis-circumscripta-unmasking-a-scalp-melanoma
#12
L Yeo, E Husain, S Rajpara
A 28-year-old man presented with a 1-year history of a localized patch of grey hair and an underlying darkly pigmented lesion on his right occipital area. Clinical appearance revealed poliosis overlying an asymmetrical plaque with variable degrees of brown pigmentation and white discolouration. Owing to the suspicious nature of the lesion, excision with a 2 mm margin was performed. Histology revealed an invasive melanoma with extensive regression and prominent involvement of multiple hair follicles. Scalp melanoma with associated poliosis is extremely rare, and has only been reported once in the literature to date...
December 2015: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/25195356/treatment-of-congenital-aniridia-associated-with-subluxated-infantile-cataract
#13
Vahid Jusufovic, Emir Cabric, Allen Popovic-Beganovic, Zlatko Musanovic, Jasmin Zvornicanin
A 5 year old boy was presented at Eye clinic University clinical center Tuzla with congenital aniridia in both eyes. Clinical examination revealed visual acuity of 0.08 without correction in right and 0.7 with -5.0 Dsph and -1.0 Dcyl Axx 109 degrees in left eye. Opthalmologic examination showed bilateral aniridia associated with moderate cataract in the right and incipient cataract in the left eye. In the right eye, zonular weakness with incipient capsular displacement and esotropia of delta6 degrees, were noted...
2014: Medicinski Arhiv
https://www.readbyqxmd.com/read/25104550/nurses-caring-for-ent-patients-in-a-district-general-hospital-without-a-dedicated-ent-ward-score-significantly-less-in-a-test-of-knowledge-than-nurses-caring-for-ent-patients-in-a-dedicated-ent-ward-in-a-comparable-district-general-hospital
#14
COMPARATIVE STUDY
C R Foxton, D Black, J Muhlschlegel, A Jardine
OBJECTIVES: To assess whether there is a difference in ENT knowledge amongst nurses caring for patients on a dedicated ENT ward and nurses caring for ENT patients in a similar hospital without a dedicated ENT ward. DESIGN: A test of theoretical knowledge of ENT nursing care was devised and administered to nurses working on a dedicated ENT ward and then to nurses working on generic non-subspecialist wards regularly caring for ENT patients in a hospital without a dedicated ENT ward...
December 2014: Clinical Otolaryngology
https://www.readbyqxmd.com/read/25029211/dental-care-access-among-individuals-with-down-syndrome-a-malaysian-scenario
#15
COMPARATIVE STUDY
Farah Salwa Abdul Rahim, Alizae Marny Mohamed, Murshida Marizan Nor, Roslan Saub
OBJECTIVE: The purpose of this cross-sectional study was to assess the legal representatives' perceptions on dental care access of individuals with Down syndrome (DS) compared to their non-DS siblings in Peninsular Malaysia. METHODS: This cross-sectional study was conducted throughout community-based rehabilitation centers (CBRC) and the Down Syndrome Organization. Legal representatives of individuals with DS within the criteria were given a structured and validated questionaire...
November 2014: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/24937936/the-safety-and-efficacy-of-day-care-cataract-surgery
#16
Emir Cabric, Jasmin Zvornicanin, Vahid Jusufovic
PURPOSE: To evaluate safety and efficacy of day care cataract surgery in developing country. PATIENTS AND METHODS: This prospective study included 200 patients planned for cataract surgery during October and November 2012 divided in to two groups, day care cataract surgery (DCCS) and inpatient cataract surgery (ICS), with same number of male and female patients right and left eyes. All patients had same operative conditions and postoperative follow up. RESULTS: The average age of patients in this study was 68...
2014: Medical Archives
https://www.readbyqxmd.com/read/24919034/response-adaptive-allocation-for-circular-data
#17
Atanu Biswas, Somak Dutta, Arnab Kumar Laha, Partho K Bakshi
Response-adaptive designs are used in phase III clinical trials to allocate a larger proportion of patients to the better treatment. Circular data is a natural outcome in many clinical trial setup, e.g., some measurements in opthalmologic studies, degrees of rotation of hand or waist, etc. There is no available work on response-adaptive designs for circular data. With reference to a dataset on cataract surgery we provide some response-adaptive designs where the responses are of circular nature and propose some test statistics for treatment comparison under adaptive data allocation procedure...
2015: Journal of Biopharmaceutical Statistics
https://www.readbyqxmd.com/read/24882964/suspected-bacterial-endophthalmitis-following-sustained-release-dexamethasone-intravitreal-implant-a-case-report
#18
Mücella Arıkan Yorgun, Melek Mutlu, Yasin Toklu, Hasan Basri Cakmak, Nurullah Cağıl
A 58-year-old man admitted to our opthalmology department with the complaint of branch retinal vein occlusion. He was treated with intravitreal Ozurdex in the right eye. Two days after the injection, the patient presented with ocular pain and the visual acuity was hand movement. A diagnosis of endophthalmitis was made. We performed emergent pars plana vitrectomy (PPV) and the implant was removed from the vitreous cavity using a retinal forceps. A combination of vancomycin 1.0 mg and amikacin 0.4 mg was injected intravitreally...
June 2014: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/24704940/unilateral-endoscopic-optic-nerve-decompression-for-idiopathic-intracranial-hypertension-a-series-of-10-patients
#19
Altay Sencer, Mehmet Osman Akcakaya, Bora Basaran, Ali Guven Yorukoglu, Aydin Aydoseli, Yavuz Aras, Fahir Sencan, Banu Satana, Ismet Aslan, Omer Faruk Unal, Nail Izgi, Ali Canbolat
OBJECTIVE: Several surgical treatment modalities, including lumboperitoneal or ventriculoperitoneal shunt surgery, subtemporal decompression, endovascular venous sinus stenting, optic nerve decompression (OND), were used in the management of idiopathic intracranial hypertension (IIH). Each surgical technique has different advantages and disadvantages. Endoscopic OND is rarely used in the management of IIH. There are only four reported cases. The aim of this study is to describe the surgical results of patients treated with this less invasive surgical technique...
November 2014: World Neurosurgery
https://www.readbyqxmd.com/read/24693308/transient-visual-loss-in-a-hepatitis-c-patient-treated-with-pegylated-interferon-alfa-2a-and-ribavirin
#20
Ligita Jancoriene, Dovile Norvydaite, Saulius Galgauskas, Evelina Balciunaite
INTRODUCTION: Patients with Hepatitis C are commonly treated with combination of Pegylated Interferon alfa-2a and Ribavirin. Less than 1% of patients receiving this treatment experience very uncommon ophthalmological side effects such as optic neuropathy and vision disorder, which are usually subclinical, mild and reversible, not requiring the withdrawal of the treatment. Retinopathy is the most commonly reported ocular side effect of interferon use, usually presenting with cotton wool spots and retinal hemorrhages...
February 2014: Hepatitis Monthly
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