keyword
MENU ▼
Read by QxMD icon Read
search

Pediatric infectious diseases

keyword
https://www.readbyqxmd.com/read/30321596/immune-reconstitution-and-infection-patterns-following-early-alemtuzumab-and-reduced-intensity-transplantation-for-non-malignant-disorders-in-pediatric-patients
#1
Sima T Bhatt, Jeffrey J Bednarski, Julia Berg, Kathryn Trinkaus, Lisa Murray, Robert Hayashi, Ginny Schulz, Monica Hente, Michael Grimley, Ka Wah Chan, Naynesh Kamani, David Jacobsohn, Michael Nieder, Gregory Hale, Lolie Yu, Roberta Adams, Jignesh Dalal, Michael A Pulsipher, Paul Haut, Sonali Chaudhury, Jeffrey Davis, Jennifer Jaroscak, Martin Andreansky, Jennifer Willert, Shalini Shenoy
Hematopoietic stem cell transplantation (HSCT) is a therapeutic option for many nonmalignant disorders (NMD) and is curative or prevents disease progression. Reduced intensity conditioning (RIC) in HSCT for NMD may reduce regimen-related acute toxicities and late complications. Myeloablation is often replaced by immune suppression in RIC regimens to support donor engraftment. The pace of immune reconstitution following immune suppression by RIC regimens is influenced by agents used, donor source, and graft-versus-host disease (GVHD) prophylaxis/treatment...
October 12, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/30312755/cd3-cd19-depleted-matched-and-mismatched-unrelated-donor-hematopoietic-stem-cell-transplant-with-targeted-t-cell-addback-is-associated-with-excellent-outcomes-in-pediatric-patients-with-non-malignant-hematologic-disorders
#2
Joseph H Oved, Yongping Wang, David M Barrett, Ellen M Levy, Yanping Huang, Dimitrios S Monos, Stephan A Grupp, Nancy J Bunin, Timothy S Olson
Unrelated donor (URD) hematopoietic stem cell transplantation (HSCT) is increasingly being utilized to cure non-malignant hematologic diseases (NMHD) in patients who lack HLA matched related donors (MRD). Both graft rejection and graft vs host disease (GVHD) remain major barriers to safe and effective transplant for these patients requiring URDs. Partial T cell depletion combined with peripheral stem cell transplantation (pTCD-PSCT), has the potential advantages of providing a high stem cell dose to facilitate rapid engraftment, maintaining cells that may facilitate engraftment, and decreasing GVHD risk compared to T replete HSCT...
October 9, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/30304444/thrombotic-and-infectious-risks-of-parenteral-nutrition-in-hospitalized-pediatric-inflammatory-bowel-disease
#3
Matthew D Egberg, Joseph A Galanko, Edward L Barnes, Michael D Kappelman
Background: Malnutrition is common in inflammatory bowel disease (IBD), requiring timely and sufficient nutritional supplementation. In patients hospitalized for active disease, symptoms and/or altered intestinal function hinder enteral nutrition feasibility. In this scenario, parenteral nutrition (PN) is used. We aimed (1) to assess the frequency of PN use between 1997 and 2012 among hospitalized pediatric patients with IBD, (2) to determine the risk of in-hospital thrombus and infection associated with PN, and (3) to identify predictors of thrombus and infection in pediatric IBD hospitalizations utilizing PN...
October 10, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/30300040/advances-and-challenges-in-recombinant-mycobacterium-bovis-bcg-based-hiv-vaccine-development-lessons-learned
#4
Athina Kilpeläinen, Milena Maya-Hoyos, Narcís Saubí, Carlos Y Soto, Joan Joseph Munne
Introduction HIV/AIDS, tuberculosis, and malaria are responsible for most human deaths produced by infectious diseases worldwide. Vaccination against HIV requires generation of memory T cells and neutralizing antibodies, mucosal immunity, and stimulation of an innate immune responses. In this context, the use of Mycobacterium bovis BCG as a live vaccine vehicle is a promising approach for T-cell induction. Areas covered In this review, we provide a comprehensive summary of the literature regarding immunogenicity studies in animal models performed since 2005...
October 9, 2018: Expert Review of Vaccines
https://www.readbyqxmd.com/read/30291520/world-society-for-pediatric-infectious-diseases-declaration-on-combating-antimicrobial-resistance-in-children
#5
EDITORIAL
Jim Buttery, Yonghong Yang, Mike Sharland
No abstract text is available yet for this article.
October 5, 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/30281549/disease-and-treatment-related-morbidity-in-adolescents-with-perinatal-hiv-infection-in-asia
#6
Adam W Bartlett, Thahira Jamal Mohamed, Tavitiya Sudjaritruk, Nia Kurniati, Revathy Nallusamy, Rawiwan Hansudewechakul, Penh Sun Ly, Khanh Huu Truong, Pagakrong Lumbiganon, Thanyawee Puthanakit, Kulkanya Chokephaibulkit, Lam Van Nguyen, Viet Chau Do, Nagalingeswaran Kumarasamy, Khairulddin Nik Nik Yusoff, Moy Siew Fong, Dewi Kumara Wati, Annette H Sohn, Azar Kariminia
BACKGROUND: Perinatally HIV-infected adolescents (PHIVA) are exposed to a chronic systemic infection and long-term antiretroviral therapy (ART), leaving them susceptible to morbidities associated with inflammation, immunodeficiency, and drug toxicity. METHODS: Data collected 2001-2016 from PHIVA aged 10-19 years within a regional Asian cohort were analysed using competing risk time-to-event and Poisson regression analyses to describe the nature and incidence of morbidity events and hospitalisations, and identify factors associated with disease-related, treatment-related, and overall morbidity...
September 29, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/30274507/the-changes-of-prevalence-and-etiology-of-pediatric-pneumonia-from-national-emergency-department-information-system-in-korea-between-2007-and-2014
#7
Eun Ju Shin, Yunsun Kim, Jin-Young Jeong, Yu Mi Jung, Mi-Hee Lee, Eun Hee Chung
PURPOSE: Understanding changes in pathogen and pneumonia prevalence among pediatric pneumonia patients is important for the prevention of infectious diseases. METHODS: We retrospectively analyzed data of children younger than 18 years diagnosed with pneumonia at 117 Emergency Departments in Korea between 2007 and 2014. RESULTS: Over the study period, 329,380 pediatric cases of pneumonia were identified. The most frequent age group was 1-3 years old (48...
September 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/30269306/chinese-clinical-practice-guidelines-for-acute-infectious-diarrhea-in-children
#8
Jie Chen, Chao-Min Wan, Si-Tang Gong, Feng Fang, Mei Sun, Yuan Qian, Ying Huang, Bao-Xi Wang, Chun-Di Xu, Li-Yan Ye, Mei Dong, Yu Jin, Zhi-Hua Huang, Qin-Bing Wu, Chao-Min Zhu, You-Hong Fang, Qi-Rong Zhu, Yong-Sui Dong
BACKGROUND: The guidelines addressed the evidence-based indications for the management of children with acute infectious diarrhea in Chinese pediatric population. DATA SOURCES: The experts group of evidence development put forward clinical problems, collects evidence, forms preliminary recommendations, and then uses open-ended discussions to form recommendations. The literature review was done for developing this guideline in databases including PubMed, Cochrane, EMBASE, China Biomedical Database, and Chinese Journal Full-text Database up to June 2013...
October 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/30266790/dynamics-and-determinants-of-the-force-of-infection-of-dengue-virus-from-1994-to-2015-in-managua-nicaragua
#9
Leah C Katzelnick, Rotem Ben-Shachar, Juan Carlos Mercado, Isabel Rodriguez-Barraquer, Douglas Elizondo, Sonia Arguello, Andrea Nuñez, Sergio Ojeda, Nery Sanchez, Brenda Lopez Mercado, Lionel Gresh, Raquel Burger-Calderon, Guillermina Kuan, Aubree Gordon, Angel Balmaseda, Eva Harris
Dengue virus (DENV) is the most prevalent human vector-borne viral disease. The force of infection (FoI), the rate at which susceptible individuals are infected in a population, is an important metric for infectious disease modeling. Understanding how and why the FoI of DENV changes over time is critical for developing immunization and vector control policies. We used age-stratified seroprevalence data from 12 years of the Pediatric Dengue Cohort Study in Nicaragua to estimate the annual FoI of DENV from 1994 to 2015...
October 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/30266431/perceptions-attitudes-and-practices-of-french-junior-physicians-regarding-antibiotic-use-and-resistance
#10
C Lévin, N Thilly, M Dousak, G Beraud, M Klesnik, S Uhan, D Nathwani, B Beovic, C Pulcini
OBJECTIVES: To assess the perceptions, attitudes, and practices of French junior physicians regarding antibiotic use and resistance, and then to identify the characteristics of junior physicians associated with appropriate practices of antibiotic use. METHOD: European junior physicians received an email invitation to complete a 49 item web questionnaire between September 2015 and January 2016. We present the French data. Multivariate regression models were used to identify the characteristics of junior physicians associated with appropriate prescription practices and with consideration of the antibiotic prescription consequences...
September 25, 2018: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/30256315/priority-needs-for-conducting-pandemic-relevant-clinical-research-with-children-in-europe-a-consensus-study-with-pediatric-clinician-researchers
#11
Micaela Gal, Nina Gobat, Nicholas A Francis, Kerenza Hood, Christopher C Butler, Julia Bielicki, Pieter L Fraaij, Mike Sharland, Jessica Jarvis, Annemarie M C van Rossum, Terho Heikkinen, Federico Martinon-Torres, Jethro Herberg, Angela Watkins, Steve A R Webb, Ronnie Moore, Prasanth Sukumar, Alistair Nichol
BACKGROUND: Infectious disease pandemics (IDP) pose a considerable global threat and can disproportionately affect vulnerable populations including children. Pediatric clinical research in pandemics is essential to improve children's healthcare and minimize risks of harm by interventions that lack an adequate evidence base for this population. The unique features of IDPs require consideration of special processes to facilitate clinical research. We aimed to obtain consensus on pediatric clinician-researchers' perceptions of the priorities to feasibly conduct clinical pediatric pandemic research in Europe...
September 25, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/30256312/term-elective-cesarean-delivery-and-offspring-infectious-morbidity-a-population-based-cohort-study
#12
Tamar Wainstock, Asnat Walfisch, Ilana Shoham-Vardi, Idit Segal, Ruslan Sergienko, Daniella Landau, Eyal Sheiner
BACKGROUND: Studies have found associations between delivery mode and offspring long-term health. We aimed to study the possible association between delivery mode and the risk for long-term infectious diseases of the offspring, during a follow- up period of up of 18 years. METHODS: A population based cohort analysis was performed comparing different subtypes of infectious morbidity leading to hospitalization among children, based on delivery mode (vaginal vs. elective cesarean)...
September 25, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/30254829/pyoderma-gangrenosum-like-wounds-in-leukocyte-adhesion-deficiency-case-report-and-review-of-literature
#13
Andrew M Simpson, Karin Chen, John F Bohnsack, Matthew N Lamont, Faizi A Siddiqi, Barbu Gociman
Leukocyte adhesion deficiency (LAD) is a rare primary immunodeficiency characterized by impairment of leukocyte migration during an inflammatory response. LAD patients can experience recurrent neutrophilic wounds similar to pyoderma gangrenosum (PG), predominantly of the skin and mucosal surfaces. There have been only a few reports addressing the management of extensive, life-threatening wounds in LAD patients. We describe here both the systemic and local management employed to successfully treat a severe PG-like cutaneous lesion in the setting of LAD in a 9-year-old female...
August 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/30254038/guideline-adoption-for-community-acquired-pneumonia-in-the-outpatient-setting
#14
Lilliam Ambroggio, Colleen Mangeot, Eileen Murtagh Kurowski, Camille Graham, Paul Korn, Marcie Strasser, Charles Cavallo, Katherine Brady, Suzanne Campanella, Caitlin Clohessy, William B Brinkman, Samir S Shah
BACKGROUND: The Pediatric Infectious Diseases Society and Infectious Diseases Society of America national childhood community-acquired pneumonia (CAP) guideline encouraged the standard evaluation and treatment of children who were managed as outpatients. Our objectives were to (1) increase adherence to guideline-recommended diagnostics and antibiotic treatment of CAP at 5 pediatric primary care practices (PPCPs) by using quality-improvement methods and (2) evaluate the association between guideline adherence and unscheduled follow-up visits...
October 2018: Pediatrics
https://www.readbyqxmd.com/read/30251234/sb5-an-adalimumab-biosimilar
#15
James E Frampton
SB5 (Imraldi® ) is a biosimilar of the reference anti-TNF monoclonal antibody adalimumab. It is approved for use in the following indications for which reference adalimumab is approved: rheumatoid arthritis (RA), juvenile idiopathic arthritis [polyarticular juvenile idiopathic arthritis (pJIA) and enthesitis-related arthritis (ERA)], axial spondyloarthritis [ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA)], psoriatic arthritis (PsA), psoriasis, pediatric plaque psoriasis, hidradenitis suppurativa (HS), Crohn's disease, pediatric Crohn's disease, ulcerative colitis (UC), and non-infectious uveitis...
September 24, 2018: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/30247365/acog-committee-opinion-no-756-optimizing-support-for-breastfeeding-as-part-of-obstetric-practice
#16
(no author information available yet)
As reproductive health experts and advocates for women's health who work in conjunction with other obstetric and pediatric health care providers, obstetrician-gynecologists are uniquely positioned to enable women to achieve their infant feeding goals. Maternity care policies and practices that support breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during prenatal care, during their maternity stay, and after the birth occurs. Enabling women to breastfeed is a public health priority because, on a population level, interruption of lactation is associated with adverse health outcomes for the woman and her child, including higher maternal risks of breast cancer, ovarian cancer, diabetes, hypertension, and heart disease, and greater infant risks of infectious disease, sudden infant death syndrome, and metabolic disease...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30247361/acog-committee-opinion-no-756-summary-optimizing-support-for-breastfeeding-as-part-of-obstetric-practice
#17
(no author information available yet)
As reproductive health experts and advocates for women's health who work in conjunction with other obstetric and pediatric health care providers, obstetrician-gynecologists are uniquely positioned to enable women to achieve their infant feeding goals. Maternity care policies and practices that support breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during prenatal care, during their maternity stay, and after the birth occurs. Enabling women to breastfeed is a public health priority because, on a population level, interruption of lactation is associated with adverse health outcomes for the woman and her child, including higher maternal risks of breast cancer, ovarian cancer, diabetes, hypertension, and heart disease, and greater infant risks of infectious disease, sudden infant death syndrome, and metabolic disease...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30241165/advancing-reliable-data-for-cancer-control-in-the-central-america-four-region
#18
Marion Piñeros, Silvina Frech, Lindsay Frazier, Mathieu Laversanne, Joaquin Barnoya, Claudia Garrido, Eduardo Gharzouzi, Andrea Chacón, Soad Fuentes Alabi, Lisseth Ruiz de Campos, Jacqueline Figueroa, Ricardo Dominguez, Ofelia Rojas, Rosario Pereira, Carla Rivera, Douglas R Morgan
The Central America Four (CA-4) region, comprising Guatemala, Honduras, El Salvador, and Nicaragua, is the largest low- and middle-income country region in the Western Hemisphere, with over 36 million inhabitants. The CA-4 nations share a common geography, history, language, and development indices, and unified with open borders in 2006. The growing CA-4 cancer burden among the noncommunicable diseases is expected to increase 73% by 2030, which argues for a regional approach to cancer control. This has driven efforts to establish population-based cancer registries as a central component of the cancer control plans...
September 2018: Journal of Global Oncology
https://www.readbyqxmd.com/read/30234071/epidemiology-of-infantile-visceral-leishmaniasis-in-western-algerian-and-the-convenience-of-serum-for-the-disease-diagnosis-by-pcr-and-immunochromatography
#19
Hadj Slimane Touria, Senouci Kheira, Midoun Nori, Bouchetara Assia, Laradj Amel, Bittar Fadi
Epidemiological situation of infantile visceral leishmaniasis (IVL), which is a public health problem in Algeria, is almost unknown in the cities of Western part of the country. The aim of this study was to analyze the epidemiological, clinical, biological, therapeutic, and evolutionary aspects of IVL in Western Algeria, to evaluate the performance of the immunochromatography as a rapid diagnostic test of the disease, and to propose a diagnosis approach by real-time polymerase chain reaction (RT-PCR) assay from the serum...
2018: International Journal of Molecular and Cellular Medicine
https://www.readbyqxmd.com/read/30223896/improving-vaccination-uptake-in-pediatric-cochlear-implant-recipients
#20
Lisa Jin, Paula Téllez, Ruth Chia, Daphne Lu, Neil K Chadha, Julie Pauwels, Simon Dobson, Hazim Al Eid, Frederick K Kozak
BACKGROUND: An Infectious Disease vaccine specialist joined our institution's Cochlear Implant Team in 2010 in order to address the high percentage of non-compliance to immunization prior to surgery identified previously from an internal review. The purpose of this study was to (1) review the immunization status of cochlear implant recipients in 2010-2014, (2) assess if introducing a vaccine specialist made a significant change in vaccination compliance and (3) elucidate any barriers to vaccination compliance...
September 17, 2018: Journal of Otolaryngology—Head & Neck Surgery
keyword
keyword
161746
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"