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Lloyd Steele, James Palmer, Amelia Lloyd, James Fotheringham, Javaid Iqbal, Ever D Grech
BACKGROUND: Lower socioeconomic status (SES) has been associated with worse outcomes after acute myocardial infarction. Data for survival after ST-elevation myocardial infarction (STEMI) by SES in the current era of primary percutaneous coronary intervention (PCI) is more limited. METHODS: Data was collected for all patients with acute STEMI undergoing primary PCI at The South Yorkshire Cardiothoracic Centre, UK between 2009 and 2014. A Cox regression analysis was used to assess differences in survival by SES quartile (using an area-level measure)...
November 23, 2018: International Journal of Cardiology
Aurélie Loyeau, Hakim Benamer, Sophie Bataille, Sarah Tepper, Thévy Boche, Lionel Lamhaut, Virginie Pirès, Benoit Simon, François Dupas, Lisa Weisslinger, Gaëlle Le Bail, Alexandre Allonneau, Jean-Michel Juliard, Yves Lambert, Frédéric Lapostolle
INTRODUCTION: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. OBJECTIVE: To compare the evolution of the age pyramid of patients with ST-elevation myocardial infarction (STEMI) according to gender. METHODS: Data from patients with STEMI managed in pre-hospital settings prospectively collected in the greater Paris area...
December 3, 2018: Journal of Clinical Medicine
Caroline E Gebhard, Catherine Gebhard, Foued Maafi, Marie-Jeanne Bertrand, Barbara E Stähli, Monika Maredziak, Susan Bengs, Ahmed Haider, Zheng W Zhang, David C Smith, Hung Q Ly
BACKGROUND: Pre-hospital delays have been associated with poor outcomes in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). It is currently unknown how environmental variables affect treatment delays in these patients. METHODS AND RESULTS: The association between environmental variables, time to treatment including transportation times and adverse in-hospital events was assessed in 1828 consecutive patients with STEMI undergoing primary PCI between 2010 and 2014 in the Montreal metropolitan area...
November 26, 2018: Science of the Total Environment
Bernhard Schwaab, Uwe Zeymer, Christina Jannowitz, David Pittrow, Anselm Gitt
AIMS: The PATIENT CARE registry aimed to document clinical characteristics of patients during cardiac rehabilitation after myocardial infarction, including the current pharmacological treatment, risk factor modification and achievement of treatment targets for low-density lipoprotein cholesterol (LDL-C). METHODS: Multicentre, prospective non-interventional study at 20 cardiac rehabilitation in-patient centres across Germany. RESULTS: A total of 1408 patients post myocardial infarction were analysed...
December 3, 2018: European Journal of Preventive Cardiology
Jin-Sun Park, Kyoung-Woo Seo, Byoung-Joo Choi, So-Yeon Choi, Myeong-Ho Yoon, Gyo-Seung Hwang, Seung-Jea Tahk, Joon-Han Shin
The ratio between the absolute number of neutrophils and the number of lymphocytes (NLR) has recently emerged as a potential new biomarker predicting worse clinical conditions ranging from infectious disease to cardiovascular disease. Prognostic significance of NLR in patients with ST-elevation myocardial infarction (STEMI) is not established. This study aimed to investigate prognostic impact of NLR in patients with STEMI.We analyzed the data and clinical outcomes of 30-day survivors with STEMI who received successful coronary intervention from 2006 to 2010...
November 2018: Medicine (Baltimore)
Yi-Hsueh Liu, Wen-Hsien Lee, Chun-Yuan Chu, Ho-Ming Su, Tsung-Hsien Lin, Hsueh-Yei Yen, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu, Po-Chao Hsu
RATIONALE: Infective endocarditis (IE) complicated with obstructive ST elevation myocardial infarction (STEMI) has been reported in the literature and which were mostly related to coronary artery embolism, obstruction, or compression. However, there has been no reported case discussing about IE complicated with nonobstructive STEMI. PATIENT CONCERNS: In this report, we report a 38-year-old female suffering from intermittent fever and was later diagnosed as IE. Initially antibiotic was given and mitral valve surgery was also arranged due to large vegetation with severe mitral regurgitation...
November 2018: Medicine (Baltimore)
Mamatha Punjee Rajarao, Abdul Malik Al Kharoosi, Prashanth Panduranga
High-sensitivity cardiac troponin T (hs-cTnT) is widely used in Oman and other Gulf countries. The availability of newer generation hs-cTnT has increased the sensitivity of diagnosing non-ST-elevation acute coronary syndrome (ACS). They utilize same antibodies as fourth-generation assay but can measure 10-fold lower levels of cTnT. Any detectable level above the 99th percentile of population suggests myocardial damage. However, the cause could be non-ACS. Therefore, the increase in sensitivity of hs-cTnT assays for ACS comes at the cost of a reduced ACS specificity because more patients with other causes of myocardial injury are detected than with previous cTnT assays...
April 2018: Heart Views: the Official Journal of the Gulf Heart Association
Randol Kennedy, Percy Adonteng-Boateng
No abstract text is available yet for this article.
November 29, 2018: American Journal of Medicine
Johanna E Bischof, Christine I Worrall, Stephen W Smith
OBJECTIVE: In the presence of inferior myocardial infarction (MI), ST depression (STD) in lead I has been claimed to be accurate for diagnosis of right ventricular (RV) MI. We sought to evaluate this claim and also whether ST Elevation (STE) in lead V1 would be helpful, with or without STD in V2. METHODS: Retrospective study of consecutive inferior STEMI, comparing ECGs of patients with, to those without, RVMI, as determined by angiographic coronary occlusion proximal to the RV marginal branch...
November 2018: Journal of Electrocardiology
Emrah Bozbeyoğlu, Emre Aslanger, Özlem Yıldırımtürk, Barış Şimşek, Can Yücel Karabay, Ayça Türer, Ömer Kozan, Muzaffer Değertekin
BACKGROUND: In a minority of the patients presenting with ST-segment elevation (STE) myocardial infarction (MI), electrocardiogram (ECG) may show a balanced STE in both anterior and inferior lead groups and may cause diagnostic confusion about involved myocardial territory. In this study, we sought ECG clues which may facilitate discriminating (1) MI location and then (2) culprit artery in patients with difficult-to-discern ECGs. MATERIAL AND METHODS: Consecutive patients with the diagnosis of STEMI were scanned and patients with ECGs displaying both anterior and inferior STE were enrolled...
November 2018: Journal of Electrocardiology
Aakash Bavishi, Travis Howard, Jooho P Kim, Brent Hiramoto, Jacob B Pierce, Parrykumar Mendapara, Jonathan Alhalel, Han-Wei Wu, Nina Srdanovich, Neil J Stone
Previous studies assessing healthcare provider compliance to the 2013 American College of Cardiology/American Heart Association (ACC/AHA) cholesterol guidelines indicate a significant underuse of statin therapy at appropriate intensity. However, data are limited in primary prevention patients. Our study aimed to evaluate the impact of the 2013 ACC/AHA guidelines through a retrospective analysis of primary prevention patients presenting with first time acute coronary syndrome (ACS). We retrospectively calculated the 10-year predicted Atherosclerotic Cardiovascular Disease (10yASCVD) risk in 1,265 patients ages 40 to 75 who presented with ACS and no previous ASCVD...
November 7, 2018: American Journal of Cardiology
Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D'Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo, Raffaele Marfella
OBJECTIVES: We evaluate whether the thrombus aspiration (TA) before primary percutaneous coronary intervention (PPCI) may improve STEMI outcomes in hyperglycemic patients. BACKGROUND: The management of hyperglycemic patients during STEMI is unclear. METHODS: We undertook an observational cohort study of 3166 first STEMI. Patients were grouped on the basis of whether they received TA or not. Moreover, among these patients we selected a subgroup of STEMI patients with hyperglycemia during the event (glycaemia > 140 mg/dl)...
November 29, 2018: Cardiovascular Diabetology
Robin Hofmann, Stefan K James
No abstract text is available yet for this article.
November 28, 2018: European Heart Journal
Yanguo Xin, Xin Chen, Wenyu Hu
No abstract text is available yet for this article.
November 28, 2018: European Heart Journal
Elena Candela, Francisco Marín, José Miguel Rivera-Caravaca, Nuria Vicente Ibarra, Luna Carrillo, María Asunción Esteve-Pastor, Teresa Lozano, Manuel Jesús Macías, Vicente Pernias, Miriam Sandín, Esteban Orenes-Piñero, Miriam Quintana-Giner, Ignacio Hortelano, Beatriz Villamía, Andrea Veliz, Mariano Valdés, Juan G Martínez-Martínez, Juan M Ruiz-Nodar
INTRODUCTION AND AIMS: Patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) are often managed conservatively. Clinical practice guidelines recommend treating these patients with the same pharmacological drugs as those who receive invasive treatment. We analyze the use of new antiplatelet drugs (NADs) and other recommended treatments in people discharged following an NSTE-ACS according to the treatment strategy used, comparing the medium-term prognosis between groups. METHODS: Prospective observational multicenter registry study in 1717 patients discharged from hospital following an ACS; 1143 patients had experienced an NSTE-ACS...
2018: PloS One
Jörg Schlotterbeck, Madhumita Chatterjee, Meinrad Gawaz, Michael Lämmerhofer
A non-targeted lipidomics workflow based on C8 core-shell particle ultra high-performance liquid chromatography (UHPLC) hyphenated to ESI-QTOF-MS in data-independent acquisition (DIA) mode with sequential window acquisition of all theoretical fragment ion spectra (SWATH) was developed and applied to differential platelet lipidomics profiling of cardiovascular disease patients (stable angina pectoris (n = 10), ST-elevated myocardial infarction (n = 13)) against healthy controls (n = 10). DIA with SWATH generates comprehensive MS and MS/MS data throughout the entire chromatograms and all study samples...
January 10, 2019: Analytica Chimica Acta
Karl Heinrich Scholz, Tim Friede, Thomas Meyer, Claudius Jacobshagen, Björn Lengenfelder, Jens Jung, Claus Fleischmann, Hiller Moehlis, Hans G Olbrich, Rainer Ott, Albrecht Elsässer, Stephen Schröder, Christian Thilo, Werner Raut, Andreas Franke, Lars S Maier, Sebastian Kg Maier
BACKGROUND: In ST-segment elevation myocardial infarction (STEMI) patients treated with percutaneous coronary intervention, direct transport from the scene to the catheterisation laboratory bypassing the emergency department has been shown to shorten times to reperfusion. The aim of this study was to investigate the effects of emergency department bypass on mortality in both haemodynamically stable and unstable STEMI patients. METHODS: The analysis is based on a large cohort of STEMI patients prospectively included in the German multicentre Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction (FITT-STEMI) trial...
November 27, 2018: European Heart Journal. Acute Cardiovascular Care
Antonio Lippolis, Paola Maria Buzzi, Ilaria Jane Romano, Annalisa De Concilio, Francesco Gentile
No abstract text is available yet for this article.
November 6, 2018: Journal of Electrocardiology
Ruben W de Winter, Rob Adams, Giovanni Amoroso, Yolande Appelman, Lucia Ten Brinke, Bart Huybrechts, Pieternel van Exter, Robbert J de Winter
INTRODUCTION: The prevalence of the junctional ST-depression with tall symmetrical T-waves in a field triage system for ST-Elevation Myocardial Infarction (STEMI) is unknown. MATERIAL AND METHODS: We prospectively collected all transmitted 12-lead electrocardiograms (ECGs) from the STEMI field triage system in Amsterdam from 2011 to 2013. Electrocardiograms with junctional ST-depression with tall symmetrical T-waves were recognized and angiographic documentation and clinical follow up were collected...
October 18, 2018: Journal of Electrocardiology
Zhengxing Huang, Wei Dong
Acute coronary syndrome (ACS), as an emergent and severe syndrome due to decreased blood flow in the coronary arteries, is a leading cause of death and serious long-term disability globally. ACS is usually caused by one of three problems: ST elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI), or unstable angina (UA). Major adverse cardiac event (MACE) prediction, as a critical tool to estimate the likelihood an individual is at risk of ACS, has been widely adopted in the early prevention and intervention of ACS...
November 20, 2018: IEEE Journal of Biomedical and Health Informatics
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