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MR texture analysis

Olga Volotskova, Xuiqi Fang, Michael Keidar, Hersh Chandarana, Indra J Das
PURPOSE: To correlate the dose response and changes in microscopic structures of the radiochromic films exposed to the clinical magnetic field in the range 1.5-3T with standard and flattening filter-free (FFF) photon beams. METHODS: The radiochromic film was cut into 5x5cm2 sheets/samples from one batch. These samples were exposed to a 1.5 Tesla (T) and/or 3T B-field from an MRI scanner using an abdominal sequence for 7 min before and after irradiation with 6 MV and/or 6 MV FFF beams...
October 20, 2018: Medical Physics
Roman M Prechtl, Daniel Wefers, Frank Jakob, Rudi F Vogel
Microbial exopolysaccharides (EPS) like xanthan are widely exploited as natural biopolymers in diverse industrial sectors. In foods, in-situ EPS formation by starter cultures allows the manufacturing of "clean labeled" products with improved textural and nutritional properties. We performed structural analyses of the cell surface-associated EPS produced by Lactobacillus plantarum TMW 1.1478, which is a promising starter culture for fermented foods. Chromatographic analyses and NMR experiments suggested an acetylated heptameric repeating unit comprised of glucose, rhamnose and galactose as major components, whereas analysis of the macromolecular HePS structure suggested an apparent molecular mass of Mr ∼2 × 106 and a root mean square (RMS) radius of ca...
December 15, 2018: Carbohydrate Polymers
Zhenyu Shu, Songhua Fang, Zhongxiang Ding, Dewang Mao, Peipei Pang, Xiangyang Gong
OBJECTIVE: To explore the application value of texture analysis of magnetic resonance images (MRI) in predicting the efficacy of neoadjuvant chemoradiotherapy(nCRT) for rectal cancer. METHODS: A total of 34 rectal cancer patients who were hospitalized at Zhejiang Provincial People's Hospital from February 2015 to April 2017 were prospectively enrolled and received 3.0T MRI examination at pre-nCRT (1 day before nCRT), early stage (at 10-day after nCRT) and middle stage (at 20-day after nCRT)...
September 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Camila Lopes Vendrami, Yuri S Velichko, Frank H Miller, Argha Chatterjee, Carolina Parada Villavicencio, Vahid Yaghmai, Robert J McCarthy
OBJECTIVE: The objective of this study was to determine whether quantitative texture analysis of MR images would improve the ability to distinguish papillary renal cell carcinoma (RCC) subtypes, compared with analysis of qualitative MRI features alone. MATERIALS AND METHODS: A total of 47 pathologically proven papillary RCC tumors were retrospectively evaluated, with 31 (66%) classified as type 1 tumors and 16 (34%) classified as type 2 tumors. MR images were reviewed by two readers to determine tumor size, signal intensity, heterogeneity, enhancement pattern, margins, perilesional stranding, vein thrombosis, and metastasis...
September 21, 2018: AJR. American Journal of Roentgenology
Su Joa Ahn, Jung Hoon Kim, Sang Joon Park, Seung Tack Kim, Joon Koo Han
PURPOSE: To investigate whether pre-operative gadoxetic acid-enhanced MRI can predict early recurrence after curative resection of single HCC using image features and texture analysis. MATERIALS AND METHODS: 179 patients with single HCC and who underwent pre-operative MRI were included. Two reviewers analyzed MR findings, including the tumor margin, peritumoral enhancement, peritumoral hypointensity on the hepatobiliary phase (HBP), diffusion restriction, capsule, tumoral fat, washout, portal-vein thrombus, signal intensity on HBP, and satellite nodule...
September 18, 2018: Abdominal Radiology
Christian B van der Pol, Andrew Chung, Christopher Lim, Niket Gandhi, Wendy Tu, Matthew D F McInnes, Nicola Schieda
While many institutions perform MRI during the work-up of urinary bladder cancer, others use MRI rarely if at all, possibly due to a variation in the reported staging accuracy and unfamiliarity with the potential benefits of performing MRI. Through increased application of functional imaging techniques including diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) imaging, there has been a resurgence of interest regarding evaluation of bladder cancer with MRI. Several recent meta-analyses have shown that MRI is accurate at differentiating between ≤T1 and T2 disease (with pooled sensitivity/specificity of ∼90/80%) and differentiating between T2 and ≥T3 disease...
October 2018: Journal of Magnetic Resonance Imaging: JMRI
M Ravanelli, A Grammatica, E Tononcelli, R Morello, M Leali, S Battocchio, G M Agazzi, M Buglione di Monale E Bastia, R Maroldi, P Nicolai, D Farina
BACKGROUND AND PURPOSE: The incidence of Oropharyngeal Squampus Cell Carcinoma (OPSCC) cases is increasing especially in the Western countries due to the spreading of human papilloma virus (HPV) infection. Radiological investigations, MRI in particular, are used in the daily clinical practice to stage OPSCC. The aim of this study was to investigate the association of quantitative MR imaging features including diffusion-weighted imaging and human papillomavirus status in oropharyngeal squamous cell carcinoma...
September 13, 2018: AJNR. American Journal of Neuroradiology
Xiao-Ning Shao, Ying-Jie Sun, Kun-Tao Xiao, Yong Zhang, Wen-Bo Zhang, Zhi-Feng Kou, Jing-Liang Cheng
The diagnosis of dilated cardiomyopathy (DCM) remains a challenge in clinical radiology. This study aimed to investigate whether texture analysis (TA) parameters on magnetic resonance T1 mapping can be helpful for the diagnosis of DCM.A total of 50 DCM cases were retrospectively screened and 24 healthy controls were prospectively recruited between March 2015 and July 2017. T1 maps were acquired using the Modified Look-Locker Inversion Recovery (MOLLI) sequence at a 3.0 T MR scanner. The endocardium and epicardium were drawn on the short-axis slices of the T1 maps by an experienced radiologist...
September 2018: Medicine (Baltimore)
Yan Ren, Xi Zhang, Wenting Rui, Haopeng Pang, Tianming Qiu, Jing Wang, Qian Xie, Teng Jin, Hua Zhang, Hong Chen, Yong Zhang, Hongbing Lu, Zhenwei Yao, Junhai Zhang, Xiaoyuan Feng
BACKGROUND: Noninvasive detection of isocitrate dehydrogenase 1 mutation (IDH1(+)) and loss of nuclear alpha thalassemia/mental retardation syndrome X-linked expression ((ATRX(-)) are clinically meaningful for molecular stratification of low-grade gliomas (LGGs). PURPOSE: To study a radiomic approach based on multiparametric MR for noninvasively determining molecular status of IDH1(+) and ATRX(-) in patients with LGG. STUDY TYPE: Retrospective, radiomics...
September 8, 2018: Journal of Magnetic Resonance Imaging: JMRI
Laura Filograna, Jacopo Lenkowicz, Francesco Cellini, Nicola Dinapoli, Stefania Manfrida, Nicola Magarelli, Antonio Leone, Cesare Colosimo, Vincenzo Valentini
OBJECTIVES: Recently, radiomic analysis has gained attention as a valuable instrument for the management of oncological patients. The aim of the study is to isolate which features of magnetic resonance imaging (MRI)-based radiomic analysis have to be considered the most significant predictors of metastasis in oncological patients with spinal bone marrow metastatic disease. MATERIALS AND METHODS: Eight oncological patients (3 lung cancer; 1 prostatic cancer; 1 esophageal cancer; 1 nasopharyngeal cancer; 1 hepatocarcinoma; 1 breast cancer) with pre-radiotherapy MR imaging for a total of 58 dorsal vertebral bodies, 29 metastatic and 29 non-metastatic were included...
September 6, 2018: La Radiologia Medica
Rishi Philip Mathew, Sudhakar Kundapur Venkatesh
PURPOSE OF REVIEW: The purpose of this review is to discuss the current imaging techniques for non-invasive assessment of liver fibrosis (LF). RECENT FINDINGS: Elastography-based techniques are the most widely used imaging methods for the evaluation of LF. Currently, MR elastography (MRE) is the most accurate non-invasive method for detection and staging of LF. Ultrasound-based vibration-controlled transient elastography (VCTE) is the most widely used as it can be easily performed at the point of care but has technical limitations especially in the obese...
August 29, 2018: Current Gastroenterology Reports
Jie Meng, Shunli Liu, Lijing Zhu, Li Zhu, Huanhuan Wang, Li Xie, Yue Guan, Jian He, Xiaofeng Yang, Zhengyang Zhou
This prospective study explored the application of texture features extracted from T2WI and apparent diffusion coefficient (ADC) maps in predicting recurrence of advanced cervical cancer patients treated with concurrent chemoradiotherapy (CCRT). We included 34 patients with advanced cervical cancer who underwent pelvic MR imaging before, during and after CCRT. Radiomic feature extraction was performed by using software at T2WI and ADC maps. The performance of texture parameters in predicting recurrence was evaluated...
July 30, 2018: Scientific Reports
Hubert Stefan Bickel
BACKGROUND: Due to often overlapping imaging features, solid renal tumors pose a diagnostic challenge. In addition, personalized therapies require exact tumor subtyping. To reduce complications, this should ideally be performed noninvasively. AIMS: The aim of this work was to provide an overview on the current state of the art and new developments in the field of noninvasive radiological phenotyping of the most common types of adult renal tumors. RESULTS: Multimodal and multiparametric imaging already enables an exact, noninvasive differentiation between many types of benign and malignant renal tumors...
October 2018: Der Radiologe
Nima Sadoughi, Satheesh Krishna, Matthew D F McInnes, Trevor A Flood, Rodney H Breau, Christopher Morash, Nicola Schieda
OBJECTIVE: The purpose of this study was to evaluate quantitative apparent diffusion coefficient (ADC) metrics for the downgrading of Gleason score (GS) 9 or 10 prostate cancer (PCa) diagnosed by means of nontargeted transrectal ultrasound-guided biopsy. MATERIALS AND METHODS: Between 2012 and 2015, 30 men with a diagnosis of GS 9 or 10 PCa at nontargeted transrectal ultrasound-guided biopsy underwent 3-T multiparametric MRI before radical prostatectomy (RP). Two radiologists blinded to the histopathologic results independently assessed multiparametric MR images using Prostate Imaging Reporting and Data System (PI-RADS) version 2...
September 2018: AJR. American Journal of Roentgenology
Brandon P Galm, E Leonardo Martinez-Salazar, Brooke Swearingen, Martin Torriani, Anne Klibanski, Miriam A Bredella, Nicholas A Tritos
BACKGROUND: There are limited predictors of prognosis in patients with clinically non-functioning pituitary adenomas (NFPAs). We hypothesized that MRI texture analysis may predict tumor recurrence or progression in patients with NFPAs undergoing transsphenoidal pituitary surgery (TSS). OBJECTIVE: To characterize texture parameters on preoperative MRI examinations in patients with NFPAs in relation to prognosis. METHODS: Retrospective study of patients with NFPAs who underwent TSS at our institution between 2009 and 2010...
September 2018: European Journal of Endocrinology
Huan Zhang, Wenhua Li, Feixiang Hu, Yiqun Sun, Tingdan Hu, Tong Tong
PURPOSE: The purpose of the study was to determine whether the pre-treated MR texture features of colorectal liver metastases (CRLMs) are predictive of therapeutic response after chemotherapy. METHODS: The study included twenty-six consecutive patients (a total of 193 liver metastasis) with unrespectable CRLMs at our institution from August 2014 to February 2016. Lesions were categorized into either responding group or non-responding group according to changes in size...
July 2, 2018: Abdominal Radiology
Ursula Heilmeier, John Mbapte Wamba, Gabby B Joseph, Karin Darakananda, Jennifer Callan, Jan Neumann, Thomas M Link
OBJECTIVE: To evaluate if baseline pathological knee conditions as assessed via single features of the MR-based Whole-Organ Magnetic Resonance Imaging Scoring (WORMS), standard T2, and T2 gray-level co-occurrence matrix (GLCM) texture parameters of knee cartilage can serve as potential long-term radiological predictors of incident total knee arthroplasty (TKA) 4-7 years later. MATERIALS AND METHODS: Baseline 3-T knee MRIs of 309 subjects from the Osteoarthritis Initiative (n = 81 TKA cases, with right-knee TKA 4-7 years after enrolment, and n = 228 TKA-free matched controls) were evaluated for the presence and severity of pathological knee conditions via modified WORMS...
June 30, 2018: Skeletal Radiology
Christophe Nioche, Fanny Orlhac, Sarah Boughdad, Sylvain Reuzé, Jessica Goya-Outi, Charlotte Robert, Claire Pellot-Barakat, Michael Soussan, Frédérique Frouin, Irène Buvat
Textural and shape analysis is gaining considerable interest in medical imaging, particularly to identify parameters characterizing tumor heterogeneity and to feed radiomic models. Here, we present a free, multiplatform, and easy-to-use freeware called LIFEx, which enables the calculation of conventional, histogram-based, textural, and shape features from PET, SPECT, MR, CT, and US images, or from any combination of imaging modalities. The application does not require any programming skills and was developed for medical imaging professionals...
August 15, 2018: Cancer Research
Manoj Mannil, Jakob M Burgstaller, Ulrike Held, Mazda Farshad, Roman Guggenberger
OBJECTIVES: The aim of this study was to apply texture analysis (TA) on paraspinal musculature in T2-weighted (T2w) magnetic resonance images (MRI) of symptomatic lumbar spinal stenosis (LSS) patients and correlate the findings with clinical outcome measures. METHODS: Ninety patients were prospectively enrolled in the multi-centric Lumbar Stenosis Outcome Study (LSOS). All patients received a T2w MRI, from which we selected axial images perpendicular to the intervertebral disc at level L3/4 for TA...
June 14, 2018: European Radiology
Ahmad Chaddad, Siham Sabri, Tamim Niazi, Bassam Abdulkarim
We propose a multiscale texture features based on Laplacian-of Gaussian (LoG) filter to predict progression free (PFS) and overall survival (OS) in patients newly diagnosed with glioblastoma (GBM). Experiments use the extracted features derived from 40 patients of GBM with T1-weighted imaging (T1-WI) and Fluid-attenuated inversion recovery (FLAIR) images that were segmented manually into areas of active tumor, necrosis, and edema. Multiscale texture features were extracted locally from each of these areas of interest using a LoG filter and the relation between features to OS and PFS was investigated using univariate (i...
June 19, 2018: Medical & Biological Engineering & Computing
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