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Andre Olivier

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https://www.readbyqxmd.com/read/30303876/mutations-of-ras-raf-proto-oncogenes-impair-survival-after-cytoreductive-surgery-and-hipec-for-peritoneal-metastasis-of-colorectal-origin
#1
Marcel André Schneider, Janina Eden, Basile Pache, Felix Laminger, Victor Lopez-Lopez, Thomas Steffen, Martin Hübner, Friedrich Kober, Sebastian Roka, Pedro Cascales Campos, Lilian Roth, Anurag Gupta, Alexander Siebenhüner, Vahan Kepenekian, Guillaume Passot, Philippe Gertsch, Olivier Glehen, Kuno Lehmann
BACKGROUND: Adequate selection of patients with peritoneal metastasis (PM) for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) remains critical for successful long-term outcomes. Factors reflecting tumor biology are currently poorly represented in the selection process. The prognostic relevance of RAS/RAF mutations in patients with PM remains unclear. METHODS: Survival data of patients with colorectal PM operated in 6 European tertiary centers were retrospectively collected and predictive factors for survival identified by Cox regression analyses...
November 2018: Annals of Surgery
https://www.readbyqxmd.com/read/30293028/designing-biochar-properties-through-the-blending-of-biomass-feedstock-with-metals-impact-on-oxyanions-adsorption-behavior
#2
Alba Dieguez-Alonso, Andrés Anca-Couce, Vladimír Frišták, Eduardo Moreno-Jiménez, Markus Bacher, Thomas D Bucheli, Giulia Cimò, Pellegrino Conte, Nikolas Hagemann, Andreas Haller, Isabel Hilber, Olivier Husson, Claudia I Kammann, Norbert Kienzl, Jens Leifeld, Thomas Rosenau, Gerhard Soja, Hans-Peter Schmidt
Metal-blending of biomass prior to pyrolysis is investigated in this work as a tool to modify biochar physico-chemical properties and its behavior as adsorbent. Six different compounds were used for metal-blending: AlCl3 , Cu(OH)2 , FeSO4 , KCl, MgCl2 and Mg(OH)2 . Pyrolysis experiments were performed at 400 and 700 °C and the characterization of biochar properties included: elemental composition, thermal stability, surface area and pore size distribution, Zeta potential, redox potential, chemical structure (with nuclear magnetic resonance) and adsorption behavior of arsenate, phosphate and nitrate...
September 20, 2018: Chemosphere
https://www.readbyqxmd.com/read/30291335/obinutuzumab-plus-lenalidomide-galen-for-the-treatment-of-relapse-refractory-aggressive-lymphoma-a-phase-ii-lysa-study
#3
Roch Houot, Guillaume Cartron, Fontanet Bijou, Sophie de Guibert, Gilles A Salles, Christophe Fruchart, Krimo Bouabdallah, Marie Maerevoet, Pierre Feugier, Steven Le Gouill, Hervé Tilly, Rene-Olivier Casasnovas, Cécile Moluçon-Chabrot, Eric Van Den Neste, Pierre Zachee, Marc Andre, Christophe Bonnet, Corinne Haioun, Achiel Van Hoof, Koen Van Eygen, Lysiane Molina, Emmanuelle Nicolas-Virelizier, Philippe Ruminy, Franck Morschhauser
No abstract text is available yet for this article.
October 5, 2018: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/30270054/overview-of-the-current-status-of-familial-hypercholesterolaemia-care-in-over-60-countries-the-eas-familial-hypercholesterolaemia-studies-collaboration-fhsc
#4
Antonio J Vallejo-Vaz, Martina De Marco, Christophe A T Stevens, Asif Akram, Tomas Freiberger, G Kees Hovingh, John J P Kastelein, Pedro Mata, Frederick J Raal, Raul D Santos, Handrean Soran, Gerald F Watts, Marianne Abifadel, Carlos A Aguilar-Salinas, Mutaz Al-Khnifsawi, Fahad A AlKindi, Fahad Alnouri, Rodrigo Alonso, Khalid Al-Rasadi, Ahmad Al-Sarraf, Tester F Ashavaid, Christoph J Binder, Martin P Bogsrud, Mafalda Bourbon, Eric Bruckert, Krzysztof Chlebus, Pablo Corral, Olivier Descamps, Ronen Durst, Marat Ezhov, Zlatko Fras, Jacques Genest, Urh Groselj, Mariko Harada-Shiba, Meral Kayikcioglu, Katarina Lalic, Carolyn S P Lam, Gustavs Latkovskis, Ulrich Laufs, Evangelos Liberopoulos, Jie Lin, Vincent Maher, Nelson Majano, A David Marais, Winfried März, Erkin Mirrakhimov, André R Miserez, Olena Mitchenko, Hapizah M Nawawi, Børge G Nordestgaard, György Paragh, Zaneta Petrulioniene, Belma Pojskic, Arman Postadzhiyan, Ashraf Reda, Željko Reiner, Wilson E Sadoh, Amirhossein Sahebkar, Abdullah Shehab, Aleksander B Shek, Mario Stoll, Ta-Chen Su, Tavintharan Subramaniam, Andrey V Susekov, Phivos Symeonides, Myra Tilney, Brian Tomlinson, Thanh-Huong Truong, Alexandros D Tselepis, Anne Tybjærg-Hansen, Alejandra Vázquez-Cárdenas, Margus Viigimaa, Branislav Vohnout, Elisabeth Widén, Shizuya Yamashita, Maciej Banach, Dan Gaita, Lixin Jiang, Lennart Nilsson, Lourdes E Santos, Heribert Schunkert, Lale Tokgözoğlu, Josip Car, Alberico L Catapano, Kausik K Ray
BACKGROUND AND AIMS: Management of familial hypercholesterolaemia (FH) may vary across different settings due to factors related to population characteristics, practice, resources and/or policies. We conducted a survey among the worldwide network of EAS FHSC Lead Investigators to provide an overview of FH status in different countries. METHODS: Lead Investigators from countries formally involved in the EAS FHSC by mid-May 2018 were invited to provide a brief report on FH status in their countries, including available information, programmes, initiatives, and management...
October 2018: Atherosclerosis
https://www.readbyqxmd.com/read/30268650/agreement-between-arthroscopic-and-imaging-study-findings-in-chronic-anterior-talo-fibular-ligament-injuries
#5
Marc Elkaïm, André Thès, Ronny Lopes, Michael Andrieu, Guillaume Cordier, François Molinier, Jonathan Benoist, Fabrice Colin, Olivier Boniface, Stéphane Guillo, Thomas Bauer
BACKGROUND: Imaging studies done to evaluate chronic ankle instability (CAI) often fail to accurately detail injuries to the anterior talo-fibular ligament (ATFL) and may, therefore, also fail to provide guidance for selecting the most appropriate surgical procedure. Arthroscopy is now an indispensable tool for accurately diagnosing ATFL injuries. This study looked at agreement between arthroscopy and imaging study assessments of ATFL injuries. The primary objective was to adapt an arthroscopic classification of chronic ATFL lesions to the pre-operative imaging study findings in order to estimate the performance of computed tomography (CT)-arthrography, ultrasonography, and magnetic resonance imaging (MRI) in diagnosing ATFL lesions, using arthroscopy as the reference standard...
September 26, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/30268068/matrix-metalloproteinase-10-deficiency-delays-atherosclerosis-progression-and-plaque-calcification
#6
Ana Purroy, Carmen Roncal, Josune Orbe, Olivier Meilhac, Miriam Belzunce, Guillermo Zalba, Ricardo Villa-Bellosta, Vicente Andrés, William C Parks, José A Páramo, José A Rodríguez
BACKGROUND AND AIMS: Matrix metalloproteinases (MMPs) have been implicated in atherosclerosis and vascular calcification. Among them, we reported that MMP10 is present in human atheroma, associated with atherosclerosis. However, it remains unclear whether MMP10 is involved in atherogenesis and vascular calcification. METHODS: MMP10 was measured in serum from patients with subclinical atherosclerosis and analyzed in carotid endarterectomies by immunostaining. ApoE-deficient mice (Apoe-/- ) were crossed to MMP10-deficient (Mmp10-/- ) mice and followed up to 20 months...
September 19, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/30259574/2018-annual-report-of-the-european-liver-transplant-registry-eltr-50-year-evolution-of-liver-transplantation
#7
René Adam, Vincent Karam, Valérie Cailliez, John G O Grady, Darius Mirza, Daniel Cherqui, Jurgen Klempnauer, Mauro Salizzoni, Johann Pratschke, Neville Jamieson, Ernest Hidalgo, Andreas Paul, Rafael Lopez Andujar, Jan Lerut, Lutz Fisher, Karim Boudjema, Constantino Fondevila, Olivier Soubrane, Philippe Bachellier, Antonio D Pinna, Gabriela Berlakovich, William Bennet, Massimo Pinzani, Peter Schemmer, Krzysztof Zieniewicz, Carlos Jimenez Romero, Paolo De Simone, Bo-Goran Ericzon, Stefan Schneeberger, Stephen J Wigmore, Joan Fabregat Prous, Michele Colledan, Robert J Porte, Sezai Yilmaz, Daniel Azoulay, Jacques Pirenne, Pal-Dag Line, Pavel Trunecka, Francis Navarro, Andres Valdivieso Lopez, Luciano De Carlis, Sebastian Rufian Pena, Eberhard Kochs, Christophe Duvoux
The purpose of this registry study was to provide an overview of trends and results of liver transplantation in Europe from 1968 to 2016. This data on liver transplantation (LT) was collected prospectively from 169 centers from 32 countries, in the European Liver Transplant Registry (ELTR) beginning in 1968. This overview provides epidemiological data, as well as information on evolution of techniques, and outcomes in liver transplantation in Europe over more than 5 decades; something that cannot be obtained from only a single center experience...
September 26, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/30245066/arthroscopic-treatment-of-chronic-ankle-instability-prospective-study-of-outcomes-in-286-patients
#8
Ronny Lopes, Michael Andrieu, Guillaume Cordier, François Molinier, Jonathan Benoist, Fabrice Colin, André Thès, Marc Elkaïm, Olivier Boniface, Stéphane Guillo, Thomas Bauer
BACKGROUND: Chronic ankle instability (CAI) is the main complication of ankle sprains and requires surgery if non-operative treatment fails. Surgical ankle stabilisation techniques can be roughly classified into two groups, namely, repair involving retensioning and suturing of the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL) and reconstruction using a tendon graft. Arthroscopic repair and reconstruction techniques for CAI have been introduced recently. The objective of this prospective multicentre study was to assess the feasibility, morbidity, and short-term outcomes of these arthroscopic ankle-stabilisation techniques...
September 21, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/30243676/arthroscopic-classification-of-chronic-anterior-talo-fibular-ligament-lesions-in-chronic-ankle-instability
#9
André Thès, Haruki Odagiri, Marc Elkaïm, Ronny Lopes, Michael Andrieu, Guillaume Cordier, François Molinier, Jonathan Benoist, Fabrice Colin, Olivier Boniface, Stéphane Guillo, Thomas Bauer
BACKGROUND: The surgical treatment of chronic ankle instability (CAI) relies chiefly on anterior talo-fibular ligament (ATFL) repair (with or without augmentation) or anatomical reconstruction with a tendon graft. Arthroscopy enables not only a complete assessment and the same-stage treatment of concomitant articular lesions, but also an accurate assessment of ligament lesions. Pre-operative imaging studies (MRI, CT, US) may fail to provide sufficient detail about chronic ATFL lesions to guide the decision between repair and reconstruction...
September 19, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/30242204/meningococcus-serogroup-c-clonal-complex-st-10217-outbreak-in-zamfara-state-northern-nigeria
#10
Brenda A Kwambana-Adams, Rahab C Amaza, Catherine Okoi, Murtala Rabiu, Archibald Worwui, Ebenezer Foster-Nyarko, Bernard Ebruke, Abdul K Sesay, Madikay Senghore, Abdullahi S Umar, Rabi Usman, Adamu Atiku, Garba Abdullahi, Yahaya Buhari, Rabiu Sani, Husaini U Bako, Bashir Abdullahi, Alliyu I Yarima, Badaru Sikiru, Aderinola Olaolu Moses, Michael O Popoola, Eme Ekeng, Adebola Olayinka, Nwando Mba, Adamu Kankia, Ibrahim N Mamadu, Ifeanyi Okudo, Mary Stephen, Olivier Ronveaux, Jason Busuttil, Jason M Mwenda, Mohammed Abdulaziz, Sulaiman A Gummi, Adebayo Adedeji, Andre Bita, Linda Omar, Mamoudou Harouna Djingarey, Wondimagegnehu Alemu, Umberto D'Alessandro, Chikwe Ihekweazu, Martin Antonio
After the successful roll out of MenAfriVac, Nigeria has experienced sequential meningitis outbreaks attributed to meningococcus serogroup C (NmC). Zamfara State in North-western Nigeria recently was at the epicentre of the largest NmC outbreak in the 21st Century with 7,140 suspected meningitis cases and 553 deaths reported between December 2016 and May 2017. The overall attack rate was 155 per 100,000 population and children 5-14 years accounted for 47% (3,369/7,140) of suspected cases. The case fatality rate (CFR) among children 5-9 years was 10%, double that reported among adults ≥ 30 years (5%)...
September 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30236390/predictors-and-clinical-impact-of-late-ventricular-arrhythmias-in-patients-with-continuous-flow-left-ventricular-assist-devices
#11
Vincent Galand, Erwan Flécher, Vincent Auffret, Stéphane Boulé, André Vincentelli, Camille Dambrin, Pierre Mondoly, Frédéric Sacher, Karine Nubret, Michel Kindo, Thomas Cardi, Philippe Gaudard, Philippe Rouvière, Magali Michel, Jean-Baptiste Gourraud, Pascal Defaye, Olivier Chavanon, Constance Verdonk, Walid Ghodbane, Edeline Pelcé, Vlad Gariboldi, Matteo Pozzi, Jean-François Obadia, Pierre-Yves Litzler, Frédéric Anselme, Gerard Babatasi, Annette Belin, Fabien Garnier, Marie Bielefeld, David Hamon, Costin Radu, Bertrand Pierre, Thierry Bourguignon, Romain Eschalier, Nicolas D'Ostrevy, Marie-Cécile Bories, Eloi Marijon, Fabrice Vanhuyse, Hugues Blangy, Jean-Philippe Verhoye, Christophe Leclercq, Raphaël P Martins
OBJECTIVES: This study aimed to evaluate the incidence, clinical impact, and predictors of late ventricular arrhythmias (VAs) in left ventricular assist device (LVAD) recipients aiming to clarify implantable cardioverter-defibrillator (ICD) indications. BACKGROUND: The arrhythmic risk and need for ICD in patients implanted with an LVAD are not very well known. METHODS: This observational study was conducted in 19 centers between 2006 and 2016...
September 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/30224647/de-novo-mutations-in-msl3-cause-an-x-linked-syndrome-marked-by-impaired-histone-h4-lysine-16-acetylation
#12
M Felicia Basilicata, Ange-Line Bruel, Giuseppe Semplicio, Claudia Isabelle Keller Valsecchi, Tuğçe Aktaş, Yannis Duffourd, Tobias Rumpf, Jenny Morton, Iben Bache, Witold G Szymanski, Christian Gilissen, Olivier Vanakker, Katrin Õunap, Gerhard Mittler, Ineke van der Burgt, Salima El Chehadeh, Megan T Cho, Rolph Pfundt, Tiong Yang Tan, Maria Kirchhoff, Björn Menten, Sarah Vergult, Kristin Lindstrom, André Reis, Diana S Johnson, Alan Fryer, Victoria McKay, Richard B Fisher, Christel Thauvin-Robinet, David Francis, Tony Roscioli, Sander Pajusalu, Kelly Radtke, Jaya Ganesh, Han G Brunner, Meredith Wilson, Laurence Faivre, Vera M Kalscheuer, Julien Thevenon, Asifa Akhtar
The etiological spectrum of ultra-rare developmental disorders remains to be fully defined. Chromatin regulatory mechanisms maintain cellular identity and function, where misregulation may lead to developmental defects. Here, we report pathogenic variations in MSL3, which encodes a member of the chromatin-associated male-specific lethal (MSL) complex responsible for bulk histone H4 lysine 16 acetylation (H4K16ac) in flies and mammals. These variants cause an X-linked syndrome affecting both sexes. Clinical features of the syndrome include global developmental delay, progressive gait disturbance, and recognizable facial dysmorphism...
October 2018: Nature Genetics
https://www.readbyqxmd.com/read/30222616/modification-of-descending-analgesia-in-aging-critical-role-of-the-prefrontal-cortex
#13
Ségolène Lithfous, Olivier Després, Thierry Pebayle, André Dufour
OBJECTIVE: Aging has been associated with increases in pain threshold and reductions in tolerance threshold, as well as a deficiency in endogenous pain inhibition. Top-down pain modulation mainly involves the frontal cortex network, which is also one of the most vulnerable brain regions in aging. Because the frontal cortex also sustains executive functions, we aimed to determine if reductions in executive functions subtended by the frontal network are associated with the lack of descending inhibitor control in healthy elderly subjects...
September 15, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/30184451/rituximab-plus-lenalidomide-in-advanced-untreated-follicular-lymphoma
#14
RANDOMIZED CONTROLLED TRIAL
Franck Morschhauser, Nathan H Fowler, Pierre Feugier, Reda Bouabdallah, Hervé Tilly, M Lia Palomba, Christophe Fruchart, Edward N Libby, Rene-Olivier Casasnovas, Ian W Flinn, Corinne Haioun, Hervé Maisonneuve, Loic Ysebaert, Nancy L Bartlett, Kamal Bouabdallah, Pauline Brice, Vincent Ribrag, Nicolas Daguindau, Steven Le Gouill, Gian M Pica, Alejandro Martin Garcia-Sancho, Armando López-Guillermo, Jean-François Larouche, Kiyoshi Ando, Maria Gomes da Silva, Marc André, Pierre Zachée, Laurie H Sehn, Kensei Tobinai, Guillaume Cartron, David Liu, Jianming Wang, Luc Xerri, Gilles A Salles
BACKGROUND: Rituximab plus chemotherapy has been shown to be effective in patients with advanced-stage, previously untreated follicular lymphoma; nevertheless, most patients will have a relapse. Combination immunotherapy with lenalidomide and rituximab is an immunomodulatory regimen that has shown promising activity in patients with indolent B-cell non-Hodgkin's lymphoma. METHODS: We conducted this multicenter, international, phase 3 superiority trial to evaluate rituximab plus lenalidomide, as compared with rituximab plus chemotherapy, in patients with previously untreated follicular lymphoma...
September 6, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/30172658/intestinal-failure-in-adults-recommendations-from-the-espen-expert-groups
#15
Loris Pironi, Olivier Corcos, Alastair Forbes, Mette Holst, Francisca Joly, Cora Jonkers, Stanislaw Klek, Simon Lal, Annika Reintam Blaser, Katie E Rollins, Anna S Sasdelli, Jon Shaffer, Andre Van Gossum, Geert Wanten, Chiara Zanfi, Dileep N Lobo
BACKGROUND & AIMS: Intestinal failure (IF) is defined as "the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth". Functionally, it may be classified as type I acute intestinal failure (AIF), type II prolonged AIF and type III chronic intestinal failure (CIF) The ESPEN Workshop on IF was held in Bologna, Italy, on 15-16 October 2017 and the aims of this document were to highlight the current state of the art and future directions for research in IF...
August 18, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/30116770/identification-of-positively-and-negatively-selected-driver-gene-mutations-associated-with-colorectal-cancer-with-microsatellite-instability
#16
Vincent Jonchere, Laetitia Marisa, Malorie Greene, Alain Virouleau, Olivier Buhard, Romane Bertrand, Magali Svrcek, Pascale Cervera, Anastasia Goloudina, Erell Guillerm, Florence Coulet, Samuel Landman, Toky Ratovomanana, Sylvie Job, Mira Ayadi, Nabila Elarouci, Lucile Armenoult, Fatiha Merabtene, Sylvie Dumont, Yann Parc, Jérémie H Lefèvre, Thierry André, Jean-François Fléjou, Agathe Guilloux, Ada Collura, Aurélien de Reyniès, Alex Duval
Background & Aims: Recent studies have shown that cancers arise as a result of the positive selection of driver somatic events in tumor DNA, with negative selection playing only a minor role, if any. However, these investigations were concerned with alterations at nonrepetitive sequences and did not take into account mutations in repetitive sequences that have very high pathophysiological relevance in the tumors showing microsatellite instability (MSI) resulting from mismatch repair deficiency investigated in the present study...
2018: Cellular and Molecular Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/30116705/weight-loss-expectations-and-determinants-in-a-large-community-based-sample
#17
Benoit Pétré, André Scheen, Olivier Ziegler, Anne-Françoise Donneau, Nadia Dardenne, Eddy Husson, Adelin Albert, Michèle Guillaume
While weight-loss expectations have primarily been studied in people enrolled in weight-loss programs, the present study explores patient expectations about weight-loss and identifies related determinants in a large, non-clinical population. 3916 volunteers (age > 18 years) participated in 2012 in a community-based survey in the French-speaking region of Belgium. Participants were asked to define "dream", "goal", "happy", "acceptable", and "disappointed" weights...
December 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/30104792/patient-led-active-tuberculosis-case-finding-in-the-democratic-republic-of-the-congo
#18
Emmanuel André, Olivier Rusumba, Carlton A Evans, Philippe Ngongo, Pasteur Sanduku, Marhegane Munguakonkwa Elvis, Habimana Ndwanyi Celestin, Ishara Rusumba Alain, Eric Mulume Musafiri, Jean-Pierre Kabuayi, Olivier le Polain de Waroux, Nadia Aït-Khaled, Michel Delmée, Francis Zech
Objective: To investigate the effect of using volunteer screeners in active tuberculosis case-finding in South Kivu, the Democratic Republic of the Congo, especially among groups at high risk of tuberculosis infection. Methods: To identify and screen high-risk groups in remote communities, we trained volunteer screeners, mainly those who had themselves received treatment for tuberculosis or had a family history of the disease. A non-profit organization was created and screeners received training on the disease and its transmission at 3-day workshops...
August 1, 2018: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/30078706/dual-roles-of-poly-da-dt-tracts-in-replication-initiation-and-fork-collapse
#19
Anthony Tubbs, Sriram Sridharan, Niek van Wietmarschen, Yaakov Maman, Elsa Callen, Andre Stanlie, Wei Wu, Xia Wu, Amanda Day, Nancy Wong, Mianmian Yin, Andres Canela, Haiqing Fu, Christophe Redon, Steven C Pruitt, Yan Jaszczyszyn, Mirit I Aladjem, Peter D Aplan, Olivier Hyrien, André Nussenzweig
Replication origins, fragile sites, and rDNA have been implicated as sources of chromosomal instability. However, the defining genomic features of replication origins and fragile sites are among the least understood elements of eukaryote genomes. Here, we map sites of replication initiation and breakage in primary cells at high resolution. We find that replication initiates between transcribed genes within nucleosome-depleted structures established by long asymmetrical poly(dA:dT) tracts flanking the initiation site...
August 23, 2018: Cell
https://www.readbyqxmd.com/read/30064988/treatment-with-camu-camu-myrciaria-dubia-prevents-obesity-by-altering-the-gut-microbiota-and-increasing-energy-expenditure-in-diet-induced-obese-mice
#20
Fernando F Anhê, Renato T Nachbar, Thibault V Varin, Jocelyn Trottier, Stéphanie Dudonné, Mélanie Le Barz, Perrine Feutry, Geneviève Pilon, Olivier Barbier, Yves Desjardins, Denis Roy, André Marette
OBJECTIVE: The consumption of fruits is strongly associated with better health and higher bacterial diversity in the gut microbiota (GM). Camu camu ( Myrciaria dubia ) is an Amazonian fruit with a unique phytochemical profile, strong antioxidant potential and purported anti-inflammatory potential. DESIGN: By using metabolic tests coupled with 16S rRNA gene-based taxonomic profiling and faecal microbial transplantation (FMT), we have assessed the effect of a crude extract of camu camu (CC) on obesity and associated immunometabolic disorders in high fat/high sucrose (HFHS)-fed mice...
July 31, 2018: Gut
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