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https://www.readbyqxmd.com/read/29771855/does-multimodal-rehabilitation-for-ankle-instability-improve-patients-self-assessed-functional-outcomes-a-network-meta-analysis
#1
Konstantinos Tsikopoulos, Dimitris Mavridis, Dimitrios Georgiannos, Haris S Vasiliadis
BACKGROUND: Although there are many nonsurgical treatment options for the primary management of chronic ankle instability, the most effective nonoperative intervention has not been defined. QUESTIONS/PURPOSES: The purpose of this study was to perform a network meta-analysis to compare the results of different standalone and/or combined nonsurgical interventions on chronic ankle instability as measured by (1) the Cumberland Ankle Instability Tool (CAIT) at 0 to 6 months after treatment and (2) treatment-related complications...
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29770316/preputialplasty-can-be-considered-an-alternative-to-circumcision-when-how-why-experience-of-italian-centre
#2
Rossella Angotti, Francesco Molinaro, Francesco Ferrara, Chiara Pellegrino, Edoardo Bindi, Giulia Fusi, Mario Messina
Background: Phimosis is a condition in which the foreskin cannot be portrayed on the glans. It is a physiological and common condition in the pediatric age. The pathological form derives from an inflammatory or traumatic lesion. Circumcision is the most common surgical treatment of phimosis but it is a controversial practice, especially in occidental world. Methods: We enrolled 61 patients with pathological phimosis (22/balanoposthitis, 18/painful erection, 21/urinary discomfort) between 2015-2017...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29769101/a-new-strategy-for-volumetric-modulated-arc-therapy-planning-using-autoplanning-based-multicriteria-optimization-for-nasopharyngeal-carcinoma
#3
Juanqi Wang, Zhi Chen, Weiwei Li, Wei Qian, Xiaosheng Wang, Weigang Hu
BACKGROUND: A new strategy for making the appropriate choice of the representative optimization parameters in planning processes and accurate selection criteria during Pareto surface navigation for general multicriteria optimization (MCO) was recommended in the study. The purpose was to combine both benefits of AutoPlanning optimization and MCO (APMCO) for achieving an individual volumetric-modulated arc therapy (VMAT) plan according to the clinically achieved patient-specific tradeoff among conflicting priorities...
May 16, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29763803/study-of-the-mozart-effect-in-children-with-epileptic-electroencephalograms
#4
Eliza Grylls, Max Kinsky, Amy Baggott, Cecile Wabnitz, Ailsa McLellan
PURPOSE: To establish if listening to Mozart's Sonata for two pianos in D major (K448) has an anti-epileptic effect on the EEGs (electroencephalograms) of children. METHODS: Forty five children (2-18 years; mean 7 years 10 months) who had epileptiform activity on EEG were recruited from those attending for scheduled EEG investigations. Mozart's Sonata for two pianos in D major (K448) and an age-appropriate control music were played during the EEG. There were five consecutive states during the record, each lasting 5 min; before Mozart music (baseline), during Mozart music, after Mozart music/before control music, during control music and after control music...
May 9, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29763654/obturator-neuromodulation-with-laparoscopic-placement-of-an-obturator-lead-for-the-treatment-of-intractable-opioid-dependent-chronic-pelvic-pain-due-to-obturator-neuralgia
#5
Richard P Marvel
Chronic pelvic pain(CPP) is a common condition in women that can have a devastating effect on quality of life. Some of the most severe forms of CPP are related to peripheral nerve injuries causing persistent neuropathic pain. This is a case of a young woman with severe opioid dependent chronic pelvic and right groin pain due to obturator neuralgia. She had failed a multitude of treatments including multiple medications, manual physical therapy, nerve blocks, surgical neurolysis and spinal cord stimulation without significant benefit...
May 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29761488/psychological-therapies-for-treatment-resistant-depression-in-adults
#6
REVIEW
Sharea Ijaz, Philippa Davies, Catherine J Williams, David Kessler, Glyn Lewis, Nicola Wiles
BACKGROUND: Antidepressants are a first-line treatment for adults with moderate to severe major depression. However, many people prescribed antidepressants for depression don't respond fully to such medication, and little evidence is available to inform the most appropriate 'next step' treatment for such patients, who may be referred to as having treatment-resistant depression (TRD). National Institute for Health and Care Excellence (NICE) guidance suggests that the 'next step' for those who do not respond to antidepressants may include a change in the dose or type of antidepressant medication, the addition of another medication, or the start of psychotherapy...
May 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29760849/acute-pulmonary-embolism-in-emergency-department-patients-despite-therapeutic-anticoagulation
#7
Michelle Y Liu, Dustin W Ballard, Jie Huang, Adina S Rauchwerger, Mary E Reed, Sean C Bouvet, David R Vinson
Introduction: Emergency department (ED) patients with acute pulmonary embolism (PE) despite therapeutic anticoagulation at the time of diagnosis are uncommonly encountered and present a diagnostic and management challenge. Their characterization and outcomes are poorly described. We sought to describe the prevalence and characteristics of therapeutically anticoagulated patients among a population of patients with acute PE in a community setting and to describe treatment changes and 30-day outcomes...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29760552/patients-receiving-chiropractic-care-in-a-neurorehabilitation-hospital-a-descriptive-study
#8
Robert D Vining, Stacie A Salsbury, W Carl Cooley, Donna Gosselin, Lance Corber, Christine M Goertz
Objectives: Individuals rehabilitating from complex neurological injury require a multidisciplinary approach, which typically does not include chiropractic care. This study describes inpatients receiving multidisciplinary rehabilitation including chiropractic care for brain injury, spinal cord injury (SCI), stroke, and other complex neurological conditions. Design: Chiropractic services were integrated into Crotched Mountain Specialty Hospital (CMSH) through this project...
2018: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/29757068/physiotherapy-interventions-for-patients-with-chronic-pelvic-pain-a-systematic-review-of-the-literature
#9
Pedro Fuentes-Márquez, Irene Cabrera-Martos, Marie Carmen Valenza
OBJECTIVE: To summarize the available scientific evidence on physiotherapy interventions in the management of chronic pelvic pain (CPP). DATA SOURCES: A systematic review of randomized controlled trials was performed. An electronic search of MEDLINE, CINAHL, and Web of Science databases was performed to identify relevant randomized trials from 2010-2016. STUDY SELECTION: Manuscripts were included if at least one of the comparison groups received a physiotherapy intervention...
May 14, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29756790/a-manual-based-phenomenological-art-therapy-for-individuals-diagnosed-with-moderate-to-severe-depression-patd-a-randomized-controlled-study
#10
Christina Blomdahl, Suzanne Guregård, Marie Rusner, Helle Wijk
OBJECTIVE: This study investigated the effects of manual-based Phenomenological Art Therapy for individuals living with depression in addition to treatment as usual (PATd/TAU) compared with only treatment as usual (TAU) for individuals diagnosed with moderate to severe depression. METHOD: 79 adults (men = 29.1%) were included in this randomized-controlled-trial (RCT), multicenter study in Sweden with an intention-to-treat design. Participants were randomized into either the PATd/TAU-group (n = 43) or TAU-group (n = 36)...
May 14, 2018: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/29756522/preclinical-testing-of-therapies-for-traumatic-brain-injury
#11
Douglas DeWitt, Bridget E Hawkins, C Edward Dixon, Patrick M Kochanek, William M Armstead, Cameron 'Dale' Bass, Helen M Bramlett, András Büki, W Dalton Dietrich, Adam R Ferguson, Edward D Hall, Ronald L Hayes, Col Sidney R Hinds Ii, Michelle LaPlaca, Joseph Long, David Meaney, Stefania Mondello, Linda Noble-Haeusslein, Samuel M Poloyac, Donald S Prough, Claudia S Robertson, Kathryn E Saatman, Sandy Richard Shultz, Deborah A Shear, Douglas H Smith, Alex Valadka, Pamela J VandeVord, Liying Zhang
Despite the large number of promising neuroprotective agents identified in experimental traumatic brain injury (TBI) studies, none has yet shown meaningful improvements in long-term outcome in clinical trials. To develop recommendations and guidelines for preclinical testing of pharmacological or biological therapies for TBI, the Moody Project for Translational Traumatic Brain Injury Research hosted a symposium attended by investigators with extensive experience in pre-clinical TBI testing. The symposium participants discussed issues related to preclinical TBI testing including experimental models, therapy and outcome selection, study design, data analysis, and dissemination...
May 14, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29756120/quantitative-image-analysis-for-evaluation-of-tumor-response-in-clinical-oncology
#12
Wen-Li Cai, Guo-Bin Hong
The objective, accurate, and standardized evaluation of tumor response to treatment is an indispensable procedure in clinical oncology. Compared to manual measurement, computer-assisted linear measurement can significantly improve the accuracy and reproducibility of tumor burden quantification. For irregular-shaped and infiltrating or diffuse tumors, which are difficult to quantify by linear measurement, computer-assisted volumetric measurement may provide a more objective and sensitive quantification to evaluate tumor response to treatment than linear measurement does...
March 2018: Chronic Diseases and Translational Medicine
https://www.readbyqxmd.com/read/29754382/3d-2d-model-to-image-registration-by-imitation-learning-for-cardiac-procedures
#13
Daniel Toth, Shun Miao, Tanja Kurzendorfer, Christopher A Rinaldi, Rui Liao, Tommaso Mansi, Kawal Rhode, Peter Mountney
PURPOSE: In cardiac interventions, such as cardiac resynchronization therapy (CRT), image guidance can be enhanced by involving preoperative models. Multimodality 3D/2D registration for image guidance, however, remains a significant research challenge for fundamentally different image data, i.e., MR to X-ray. Registration methods must account for differences in intensity, contrast levels, resolution, dimensionality, field of view. Furthermore, same anatomical structures may not be visible in both modalities...
May 12, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29752186/midterm-and-long-term-results-of-ethanol-embolization-of-auricular-arteriovenous-malformations-as-first-line-therapy
#14
Chen Hua, Yunbo Jin, Xi Yang, Yun Zou, Tianyou Wang, Hao Gu, Congzhen Qiao, Zimin Zhang, Xiaoxi Lin
OBJECTIVE: The objective of this study was to assess the midterm and long-term results of patients with auricular arteriovenous malformations (AVMs) treated by ethanol embolization. METHODS: Medical records of 35 patients (20 male, 15 female; age range, 10-59 years) with auricular AVMs between 2006 and 2016 were reviewed. The short-term results of 4 of the 35 patients were reported in 2009. They were included in this study with updated follow-up data. The data from the 31 new included patients have not been reported previously...
May 8, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29752028/the-cognitive-orientation-to-daily-occupational-performance-co-op-approach-best-responders-in-children-with-cerebral-palsy-and-brain-injury
#15
Michelle Jackman, Iona Novak, Natasha A Lannin, Claire Galea, Elspeth Froude
BACKGROUND: Identifying the characteristics of individuals who are most likely to respond to a certain rehabilitation intervention is advantageous for the child, family, clinicians and the healthcare system. AIM: To investigate the individual characteristics of children with cerebral palsy or brain injury who responded best to the Cognitive Orientation to daily Occupational Performance (CO-OP) Approach. METHODS: Post hoc analyses were conducted on 30 participants who participated in CO-OP within a larger randomized controlled trial...
May 8, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29750006/a-novel-integrated-cognitive-behavioral-therapy-for-anxiety-and-medication-adherence-among-persons-living-with-hiv-aids
#16
Charles P Brandt, Daniel J Paulus, Monica Garza, Chad Lemaire, Peter J Norton, Michael J Zvolensky
Persons living with HIV/AIDS (PLHIV) are able to live full lifespans after infection, however, rates of anxiety disorders among this population are elevated compared to national samples. Importantly, these anxiety symptoms and disorders have a negative effect on medication adherence, quality of life and other psychological disorders, such as depression. In order to reduce the impact of anxiety among PLHIV, a six-session transdiagnostic CBT-based treatment manual for anxiety among PLHIV named the HIV/Anxiety Management-Reduction Treatment (HAMRT) was developed and implemented...
February 2018: Cognitive and Behavioral Practice
https://www.readbyqxmd.com/read/29747035/microscale-radiosynthesis-preclinical-imaging-and-dosimetry-study-of-18-f-ambf-3-tate-a-potential-pet-tracer-for-clinical-imaging-of-somatostatin-receptors
#17
Ksenia Lisova, Maxim Sergeev, Susan Evans-Axelsson, Andreea D Stuparu, Seval Beykan, Jeffrey Collins, Jason Jones, Michael Lassmann, Ken Herrmann, David Perrin, Jason T Lee, Roger Slavik, R Michael van Dam
BACKGROUND: Peptides labeled with positron-emitting isotopes are emerging as a versatile class of compounds for the development of highly specific, targeted imaging agents for diagnostic imaging via positron-emission tomography (PET) and for precision medicine via theranostic applications. Despite the success of peptides labeled with gallium-68 (for imaging) or lutetium-177 (for therapy) in the clinical management of patients with neuroendocrine tumors or prostate cancer, there are significant advantages of using fluorine-18 for imaging...
April 20, 2018: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/29746413/intravitreal-anti-vascular-endothelial-growth-factor-treatment-at-2-month-intervals-reduces-foveal-avascular-zone-enlargement-and-vision-loss-in-radiation-maculopathy-a-pilot-study
#18
Alejandra Daruich, Alexandre Matet, Ann Schalenbourg, Leonidas Zografos
PURPOSE: To evaluate, in eyes with radiation maculopathy, the effect of 2-month-interval anti-vascular endothelial growth factor therapy on best-corrected visual acuity and foveal avascular zone (FAZ) enlargement using optical coherence tomography angiography. METHODS: Consecutive treatment-naive patients with radiation maculopathy after proton beam irradiation for choroidal melanoma were retrospectively included. Clinical and optical coherence tomography angiography data at baseline and the 6-month visit were recorded...
May 3, 2018: Retina
https://www.readbyqxmd.com/read/29742583/adjunct-ketamine-use-in-the-management-of-severe-ethanol-withdrawal
#19
Anthony F Pizon, Michael J Lynch, Neal J Benedict, Joseph H Yanta, Adam Frisch, Nathan B Menke, Greg S Swartzentruber, Andrew M King, Michael G Abesamis, Sandra L Kane-Gill
OBJECTIVES: Ketamine offers a plausible mechanism with favorable kinetics in treatment of severe ethanol withdrawal. The purpose of this study is to determine if a treatment guideline using an adjunctive ketamine infusion improves outcomes in patients suffering from severe ethanol withdrawal. DESIGN: Retrospective observational cohort study. SETTING: Academic tertiary care hospital. PATIENTS: Patients admitted to the ICU and diagnosed with delirium tremens by Diagnostic and Statistical Manual of Mental Disorders V criteria...
May 8, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29739529/where-is-the-evidence-for-evidence-based-therapy
#20
REVIEW
Jonathan Shedler
The term evidence-based therapy is a de facto code word for manualized therapy, most often brief cognitive behavior therapy and its variants. It is widely asserted that "evidence-based" therapy is scientifically proven, superior to other forms of psychotherapy, and the gold standard of care. Research findings do not support such assertions. Research on evidence-based therapies demonstrates that they are weak treatments. They have not shown superiority to other forms of psychotherapy, few patients get well, and treatment benefits do not last...
June 2018: Psychiatric Clinics of North America
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